Statistics of regulated genes

Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11
Lactococcus lactis subsp. lactis Il1403
Streptococcus agalactiae 2603V/R	12	3
Streptococcus dysgalactiae subsp. equisimilis GGS_124	6	2
Streptococcus equi subsp. zooepidemicus MGCS10565	10	2
Streptococcus gallolyticus UCN34
Streptococcus gordonii str. Challis substr. CH1
Streptococcus mitis B6
Streptococcus mutans UA159
Streptococcus pneumoniae TIGR4	15	3
Streptococcus pyogenes M1 GAS	12	3
Streptococcus sanguinis SK36
Streptococcus suis 05ZYH33	14	2
Streptococcus thermophilus CNRZ1066
Streptococcus uberis 0140J

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																Function
CRON 1.
hylD	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -32 score = 5.12804 sequence = AAAGTAAACCGGTAAACTCA Site: position = -251 score = 5.09009 sequence = GAAGTAAACCTGTTTACATG Site: position = -222 score = 5.85934 sequence = AAAGTAAACCGGTTTTGTCA Gene: SAG1902: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -33 score = 5.3494 sequence = TAAGTAAACCGGTAAACTAA Site: position = -280 score = 5.11186 sequence = AAAGTAAACTAGTTTTGTCA Gene: SDEG_0648: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -281 score = 6.0807 sequence = TAAGTAAACCTGTTTACCAA Site: position = -33 score = 5.3494 sequence = TAAGTAAACCGGTAAACTAA Gene: Sez_1304: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	* Streptococcus pneumoniae TIGR4 Site: position = -219 score = 5.62835 sequence = CTAGTAAACCGGTTTTGTCA Site: position = -37 score = 5.03919 sequence = AAAGTAAACCGGTAAACCTA Gene: SP_0321: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	* Streptococcus pyogenes M1 GAS Site: position = -33 score = 4.6043 sequence = TGAGTAAACCGGTAAACCGA Site: position = -281 score = 5.11186 sequence = AAAGTAAACTAGTTTTGTCA Gene: SPy0634: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	Streptococcus sanguinis SK36	* Streptococcus suis 05ZYH33 Site: position = -33 score = 4.91289 sequence = TAGGTAAACCGGTAAAGTTA Gene: SSU05_1221: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)
ugl	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1901: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0647: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1305: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0322: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus pyogenes M1 GAS Gene: SPy0632: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1220: Unsaturated glucuronyl hydrolase (EC 3.2.1.-)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Unsaturated glucuronyl hydrolase (EC 3.2.1.-)
hylE	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1900: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0646: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1306: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0323: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS Gene: SPy0631: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1219: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)
hylF	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1899: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0645: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1307: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0324: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS Gene: SPy0630: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1218: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)
hylG	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1898: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0644: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1308: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0325: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS Gene: SPy0629: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1217: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)
yajC	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0326: Preprotein translocase subunit YajC (TC 3.A.5.1.1)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1216: Preprotein translocase subunit YajC (TC 3.A.5.1.1)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Preprotein translocase subunit YajC (TC 3.A.5.1.1)
ohl	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1897: Oligohyaluronate lyase (EC 4.2.2.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0643: Oligohyaluronate lyase (EC 4.2.2.-)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	2 Streptococcus pneumoniae TIGR4 Gene: SP_0327: Oligohyaluronate lyase (EC 4.2.2.-) Gene: SP_0329: Oligohyaluronate lyase (EC 4.2.2.-)	Streptococcus pyogenes M1 GAS Gene: SPy0628: Oligohyaluronate lyase (EC 4.2.2.-)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1211: Oligohyaluronate lyase (EC 4.2.2.-)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Oligohyaluronate lyase (EC 4.2.2.-)
SP_1439	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0328: IS1380-Spn1, transposase	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	IS1380-Spn1, transposase
regR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1896: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0642: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1309: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0330: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus pyogenes M1 GAS Gene: SPy0627: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1210: Transcriptional regulator of hyaluronate and KDG utilization, LacI family	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Transcriptional regulator of hyaluronate and KDG utilization, LacI family
hyl	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -42 score = 5.03814 sequence = AGGAAAAACCGGTTTACAAT Gene: SAG1197: Hyaluronate lyase precursor (EC 4.2.2.1)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0654: Hyaluronate lyase precursor (EC 4.2.2.1)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1299: Hyaluronate lyase precursor (EC 4.2.2.1)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	* Streptococcus pneumoniae TIGR4 Site: position = -89 score = 6.23897 sequence = TAATTAAACCGGTTTACTTA Gene: SP_0314: Hyaluronate lyase precursor (EC 4.2.2.1)	* Streptococcus pyogenes M1 GAS Site: position = -54 score = 5.45941 sequence = TTAGTAAATCAATTTACTTT Gene: SPy1032: Hyaluronate lyase precursor (EC 4.2.2.1)	Streptococcus sanguinis SK36	4 Streptococcus suis 05ZYH33 Gene: SSU05_1214: Hyaluronate lyase precursor (EC 4.2.2.1) Gene: SSU05_1215: Hyaluronate lyase precursor (EC 4.2.2.1) Gene: SSU05_1212: Hyaluronate lyase precursor (EC 4.2.2.1) Gene: SSU05_1213: Hyaluronate lyase precursor (EC 4.2.2.1)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Hyaluronate lyase precursor (EC 4.2.2.1)
kduD	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -265 score = 5.12804 sequence = TGAGTTTACCGGTTTACTTT Site: position = -46 score = 5.09009 sequence = CATGTAAACAGGTTTACTTC Site: position = -75 score = 5.85934 sequence = TGACAAAACCGGTTTACTTT Gene: SAG1904: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -74 score = 5.11186 sequence = TGACAAAACTAGTTTACTTT Site: position = -45 score = 6.0807 sequence = TTGGTAAACAGGTTTACTTA Gene: SDEG_0650: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -293 score = 5.3494 sequence = TTAGTTTACCGGTTTACTTA Site: position = -45 score = 6.0807 sequence = TTGGTAAACAGGTTTACTTA Gene: Sez_1303: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	* Streptococcus pneumoniae TIGR4 Site: position = -253 score = 5.03919 sequence = TAGGTTTACCGGTTTACTTT Site: position = -71 score = 5.62835 sequence = TGACAAAACCGGTTTACTAG Gene: SP_0320: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	* Streptococcus pyogenes M1 GAS Site: position = -45 score = 6.0807 sequence = TTGGTAAACAGGTTTACTTA Site: position = -74 score = 5.11186 sequence = TGACAAAACTAGTTTACTTT Gene: SPy0636: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	Streptococcus sanguinis SK36	* Streptococcus suis 05ZYH33 Site: position = -75 score = 5.82847 sequence = TGACAAAACCGGTTTACTAT Gene: SSU05_1225: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)
kduI	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1905: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0651: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1302: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0319: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus pyogenes M1 GAS Gene: SPy0637: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1224: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)
kdgK	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1906: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0652: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1301: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0318: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus pyogenes M1 GAS Gene: SPy0638: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1223: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
kdgA	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1907: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0653: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1300: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0317: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus pyogenes M1 GAS Gene: SPy0639: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_1222: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)

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