Regulon of McbR in Corynebacterium urealyticum DSM 7109
| Regulator type: | Transcription factor |
| TF locus tag: | cur_0113 |
| Regulator family: | TetR |
| Regulation mode: | repressor |
| Biological process: | Methionine biosynthesis |
| Effector: | S-adenosylmethionine; S-adenosylhomocysteine |
| Regulog: | McbR - Corynebacteriaceae |
| Statistics of regulated genes: | |
| - Genes | 26 |
| - Operons | 13 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Corynebacteriaceae
- By TF family - TetR
- By effector - S-adenosylmethionine
- By effector - S-adenosylhomocysteine
- By pathway - Methionine biosynthesis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -256
Score: 5 Sequence: CAGACCAAGCTGTCTA
Locus tag: cur_1766
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14) |
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metE
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5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
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Position: -183
Score: 4.8 Sequence: TAGACCGCATGGTCTG
Position: -105
Score: 4.6 Sequence: TAGACAGTTCGGTATG
Position: -39
Score: 5 Sequence: TAGACAGATCGGTTCA
Locus tag: cur_0176
Name: CE2728 Funciton: Predicted permease protein |
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CE2728
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Predicted permease protein
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Position: -61
Score: 4.9 Sequence: TGAACAGATCTGTCTA
Locus tag: cur_0252
Name: cg2679 Funciton: Conserved hypothetical protein |
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cg2679
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Conserved hypothetical protein
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Position: -41
Score: 5 Sequence: TAGACAGATCTGTTCA
Locus tag: cur_0251
Name: cg2678 Funciton: Predicted ABC transporter, substrate-binding protein
Locus tag: cur_0250
Name: cg2677 Funciton: Predicted ABC transporter, permease protein 1
Locus tag: cur_0249
Name: cg2676 Funciton: Predicted ABC transporter, permease protein 2
Locus tag: cur_0248
Name: cg2675 Funciton: Predicted ABC transporter, ATP-binding protein |
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cg2678
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Predicted ABC transporter, substrate-binding protein
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cg2677
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Predicted ABC transporter, permease protein 1
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cg2676
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Predicted ABC transporter, permease protein 2
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cg2675
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Predicted ABC transporter, ATP-binding protein
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Position: -60
Score: 5.3 Sequence: TAGACAGATCAGTCTA
Locus tag: cur_1592
Name: cysK Funciton: Cysteine synthase (EC 2.5.1.47)
Locus tag: cur_1593
Name: cysE Funciton: Serine acetyltransferase (EC 2.3.1.30) |
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cysK
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Cysteine synthase (EC 2.5.1.47)
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cysE
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Serine acetyltransferase (EC 2.3.1.30)
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Position: -127
Score: 4.9 Sequence: TAGACCAAGTTGTCCA
Locus tag: cur_0411
Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
Locus tag: cur_0410
Name: metN Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: cur_0409
Name: metI Funciton: Methionine ABC transporter permease protein |
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metQ
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Methionine ABC transporter substrate-binding protein
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metN
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Methionine ABC transporter ATP-binding protein
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metI
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Methionine ABC transporter permease protein
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Position: -212
Score: 4.9 Sequence: TAGACCAAGTGGTATA
Position: -145
Score: 5.2 Sequence: TAGACAGAGCGGTTTA
Locus tag: cur_0423
Name: metY Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Locus tag: cur_0422
Name: metX Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31) |
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metY
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O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
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metX
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Homoserine O-acetyltransferase (EC 2.3.1.31)
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Position: -9
Score: 5 Sequence: TAGACAGAGATGTCTA
Locus tag: cur_1218
Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
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metF
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5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
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Position: -208
Score: 4.9 Sequence: CAGACCGTGCGGTCTA
Position: -124
Score: 5 Sequence: TAGACAATGCTGTCTA
Locus tag: cur_1758
Name: cysJ Funciton: Ferredoxin--NADP reductase (EC 1.18.1.2) |
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cysJ
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Ferredoxin--NADP reductase (EC 1.18.1.2)
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Position: -134
Score: 5.5 Sequence: TAGACAGCTTGGTCTA
Locus tag: cur_0694
Name: hom Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: cur_0695
Name: thrB Funciton: Homoserine kinase (EC 2.7.1.39) |
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hom
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Homoserine dehydrogenase (EC 1.1.1.3)
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thrB
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Homoserine kinase (EC 2.7.1.39)
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Position: -110
Score: 5.4 Sequence: TAGACCGCTTGGTCTA
Locus tag: cur_0975
Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Locus tag: cur_0976
Name: priA Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication |
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metK
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S-adenosylmethionine synthetase (EC 2.5.1.6)
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priA
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Helicase PriA essential for oriC/DnaA-independent DNA replication
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Position: -219
Score: 4.9 Sequence: TAGACCAGGCGGTCTA
Position: -111
Score: 5.1 Sequence: TAGACCGAGCGGTCTG
Locus tag: cur_1744
Name: cysH Funciton: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: cur_1743
Name: cysD Funciton: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
Locus tag: cur_1742
Name: cysN Funciton: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
Locus tag: cur_1741
Name: cysY Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: cur_1740
Name: cysZ Funciton: Sulfate transporter, CysZ-type |
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cysH
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Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
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cysD
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Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
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cysN
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Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
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cysY
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Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
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cysZ
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Sulfate transporter, CysZ-type
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Position: -181
Score: 5.2 Sequence: TAGACAGCATTGTCTA
Position: -97
Score: 4.9 Sequence: TAGACCGCACGGTCTG
Locus tag: cur_1757
Name: cysI Funciton: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1) |
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cysI
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Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |