Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of McbR in Corynebacterium urealyticum DSM 7109

Properties
Regulator type: Transcription factor
TF locus tag: cur_0113
Regulator family: TetR
Regulation mode: repressor
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine; S-adenosylhomocysteine
Regulog: McbR - Corynebacteriaceae
Statistics of regulated genes:
- Genes 26
- Operons 13
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 162 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -256
Score: 5
Sequence: CAGACCAAGCTGTCTA
Locus tag: cur_1766
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
cur_1766
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
Position: -183
Score: 4.8
Sequence: TAGACCGCATGGTCTG
Position: -105
Score: 4.6
Sequence: TAGACAGTTCGGTATG
Position: -39
Score: 5
Sequence: TAGACAGATCGGTTCA
Locus tag: cur_0176
Name: CE2728
Funciton: Predicted permease protein
cur_0176
CE2728
Predicted permease protein
Position: -61
Score: 4.9
Sequence: TGAACAGATCTGTCTA
Locus tag: cur_0252
Name: cg2679
Funciton: Conserved hypothetical protein
cur_0252
cg2679
Conserved hypothetical protein
Position: -41
Score: 5
Sequence: TAGACAGATCTGTTCA
Locus tag: cur_0251
Name: cg2678
Funciton: Predicted ABC transporter, substrate-binding protein
Locus tag: cur_0250
Name: cg2677
Funciton: Predicted ABC transporter, permease protein 1
Locus tag: cur_0249
Name: cg2676
Funciton: Predicted ABC transporter, permease protein 2
Locus tag: cur_0248
Name: cg2675
Funciton: Predicted ABC transporter, ATP-binding protein
cur_0251
cg2678
Predicted ABC transporter, substrate-binding protein
cur_0250
cg2677
Predicted ABC transporter, permease protein 1
cur_0249
cg2676
Predicted ABC transporter, permease protein 2
cur_0248
cg2675
Predicted ABC transporter, ATP-binding protein
Position: -60
Score: 5.3
Sequence: TAGACAGATCAGTCTA
Locus tag: cur_1592
Name: cysK
Funciton: Cysteine synthase (EC 2.5.1.47)
Locus tag: cur_1593
Name: cysE
Funciton: Serine acetyltransferase (EC 2.3.1.30)
cur_1592
cysK
Cysteine synthase (EC 2.5.1.47)
cur_1593
cysE
Serine acetyltransferase (EC 2.3.1.30)
Position: -127
Score: 4.9
Sequence: TAGACCAAGTTGTCCA
Locus tag: cur_0411
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
Locus tag: cur_0410
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: cur_0409
Name: metI
Funciton: Methionine ABC transporter permease protein
cur_0411
metQ
Methionine ABC transporter substrate-binding protein
cur_0410
metN
Methionine ABC transporter ATP-binding protein
cur_0409
metI
Methionine ABC transporter permease protein
Position: -212
Score: 4.9
Sequence: TAGACCAAGTGGTATA
Position: -145
Score: 5.2
Sequence: TAGACAGAGCGGTTTA
Locus tag: cur_0423
Name: metY
Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Locus tag: cur_0422
Name: metX
Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31)
cur_0423
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
cur_0422
metX
Homoserine O-acetyltransferase (EC 2.3.1.31)
Position: -9
Score: 5
Sequence: TAGACAGAGATGTCTA
Locus tag: cur_1218
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
cur_1218
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -208
Score: 4.9
Sequence: CAGACCGTGCGGTCTA
Position: -124
Score: 5
Sequence: TAGACAATGCTGTCTA
Locus tag: cur_1758
Name: cysJ
Funciton: Ferredoxin--NADP reductase (EC 1.18.1.2)
cur_1758
cysJ
Ferredoxin--NADP reductase (EC 1.18.1.2)
Position: -134
Score: 5.5
Sequence: TAGACAGCTTGGTCTA
Locus tag: cur_0694
Name: hom
Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: cur_0695
Name: thrB
Funciton: Homoserine kinase (EC 2.7.1.39)
cur_0694
hom
Homoserine dehydrogenase (EC 1.1.1.3)
cur_0695
thrB
Homoserine kinase (EC 2.7.1.39)
Position: -110
Score: 5.4
Sequence: TAGACCGCTTGGTCTA
Locus tag: cur_0975
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Locus tag: cur_0976
Name: priA
Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication
cur_0975
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
cur_0976
priA
Helicase PriA essential for oriC/DnaA-independent DNA replication
Position: -219
Score: 4.9
Sequence: TAGACCAGGCGGTCTA
Position: -111
Score: 5.1
Sequence: TAGACCGAGCGGTCTG
Locus tag: cur_1744
Name: cysH
Funciton: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: cur_1743
Name: cysD
Funciton: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
Locus tag: cur_1742
Name: cysN
Funciton: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
Locus tag: cur_1741
Name: cysY
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: cur_1740
Name: cysZ
Funciton: Sulfate transporter, CysZ-type
cur_1744
cysH
Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
cur_1743
cysD
Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
cur_1742
cysN
Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
cur_1741
cysY
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
cur_1740
cysZ
Sulfate transporter, CysZ-type
Position: -181
Score: 5.2
Sequence: TAGACAGCATTGTCTA
Position: -97
Score: 4.9
Sequence: TAGACCGCACGGTCTG
Locus tag: cur_1757
Name: cysI
Funciton: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
cur_1757
cysI
Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
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