Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of McbR in Corynebacterium jeikeium K411

Properties
Regulator type: Transcription factor
TF locus tag: jk0101
Regulator family: TetR
Regulation mode: repressor
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine; S-adenosylhomocysteine
Regulog: McbR - Corynebacteriaceae
Statistics of regulated genes:
- Genes 25
- Operons 14
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 162 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -205
Score: 4.8
Sequence: CAGACTAAGCTGTCTA
Locus tag: jk0234
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
jk0234
metE
5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
Position: -134
Score: 5.3
Sequence: TGGACAGATTGGTCTA
Position: -100
Score: 4.9
Sequence: CAGACCGATCGGTCTG
Locus tag: jk0245
Name: cysH
Funciton: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: jk0246
Name: cysD
Funciton: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
Locus tag: jk0247
Name: cysN
Funciton: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
Locus tag: jk0248
Name: cysY
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
jk0245
cysH
Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
jk0246
cysD
Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
jk0247
cysN
Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
jk0248
cysY
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Position: -114
Score: 5.4
Sequence: TAGACAACTCTGTCTA
Position: -34
Score: 5
Sequence: CAGACAGATCAGTCTA
Locus tag: jk0243
Name: cysI
Funciton: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Locus tag: jk0244
Name: cysX
Funciton: Ferredoxin-like protein involved in electron transfer
jk0243
cysI
Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
jk0244
cysX
Ferredoxin-like protein involved in electron transfer
Position: -41
Score: 4.7
Sequence: CAGACAGATCGGTTCA
Locus tag: jk0156
Name: CE2728
Funciton: Predicted permease protein
jk0156
CE2728
Predicted permease protein
Position: -30
Score: 4.9
Sequence: TAGACCAAGCGGTCTG
Locus tag: jk0976
Name: cg1739
Funciton: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
jk0976
cg1739
GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
Position: -35
Score: 5.2
Sequence: TAGACCGATCAGTCTA
Locus tag: jk0394
Name: cysK
Funciton: Cysteine synthase (EC 2.5.1.47)
Locus tag: jk0393
Name: cysE
Funciton: Serine acetyltransferase (EC 2.3.1.30)
jk0394
cysK
Cysteine synthase (EC 2.5.1.47)
jk0393
cysE
Serine acetyltransferase (EC 2.3.1.30)
Position: -171
Score: 4.5
Sequence: TAGACCAAGCGGTATG
Position: -93
Score: 5.2
Sequence: TAGACAGAGCGGTTTA
Locus tag: jk1694
Name: metY
Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Locus tag: jk1695
Name: metX
Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31)
jk1694
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
jk1695
metX
Homoserine O-acetyltransferase (EC 2.3.1.31)
Position: -297
Score: 4.9
Sequence: TAGACTGATCTGTCTG
Position: -217
Score: 5.4
Sequence: TAGACAGAGTTGTCTA
Locus tag: jk0242
Name: cysJ
Funciton: Ferredoxin--NADP reductase (EC 1.18.1.2)
jk0242
cysJ
Ferredoxin--NADP reductase (EC 1.18.1.2)
Position: -30
Score: 5.3
Sequence: TGGACAGCTCTGTCTA
Locus tag: jk0737
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
jk0737
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -105
Score: 5.2
Sequence: TGGACAGCTTTGTCTA
Locus tag: jk1352
Name: hom
Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: jk1351
Name: thrC
Funciton: Threonine synthase (EC 4.2.3.1)
Locus tag: jk1350
Name: thrB
Funciton: Homoserine kinase (EC 2.7.1.39)
jk1352
hom
Homoserine dehydrogenase (EC 1.1.1.3)
jk1351
thrC
Threonine synthase (EC 4.2.3.1)
jk1350
thrB
Homoserine kinase (EC 2.7.1.39)
Position: -75
Score: 5.2
Sequence: CAGACAGCTTGGTCTA
Locus tag: jk1016
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Locus tag: jk1015
Name: priA
Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication
jk1016
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
jk1015
priA
Helicase PriA essential for oriC/DnaA-independent DNA replication
Position: -108
Score: 5.3
Sequence: TAGACTGCTTGGTCTA
Locus tag: jk0055
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
jk0055
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
Position: -23
Score: 4.2
Sequence: TAGACAGCAAGGACTA
Locus tag: jk0249
Name: cysZ
Funciton: Sulfate transporter, CysZ-type
jk0249
cysZ
Sulfate transporter, CysZ-type
Position: -103
Score: 4.5
Sequence: TAGACTAAGTTGTTCA
Locus tag: jk1710
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
Locus tag: jk1711
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: jk1712
Name: metI
Funciton: Methionine ABC transporter permease protein
jk1710
metQ
Methionine ABC transporter substrate-binding protein
jk1711
metN
Methionine ABC transporter ATP-binding protein
jk1712
metI
Methionine ABC transporter permease protein
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