Regulon of McbR in Corynebacterium efficiens YS-314
| Regulator type: | Transcription factor |
| TF locus tag: | CE2788 |
| Regulator family: | TetR |
| Regulation mode: | repressor |
| Biological process: | Methionine biosynthesis |
| Effector: | S-adenosylmethionine; S-adenosylhomocysteine |
| Regulog: | McbR - Corynebacteriaceae |
| Statistics of regulated genes: | |
| - Genes | 34 |
| - Operons | 16 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Corynebacteriaceae
- By TF family - TetR
- By effector - S-adenosylmethionine
- By effector - S-adenosylhomocysteine
- By pathway - Methionine biosynthesis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -290
Score: 4.3 Sequence: CAGACCATGCTGTCTG
Locus tag: CE1209
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14) |
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metE
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5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (EC 2.1.1.14)
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Position: -20
Score: 4.2 Sequence: CGTACTAAGCTGTCTA
Locus tag: CE1637
Name: metH Funciton: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13) |
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metH
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5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
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Position: -139
Score: 4.6 Sequence: CGAACCGCTCGGTCTA
Position: -117
Score: 4.9 Sequence: TAGACCGAGCGGTTCA
Locus tag: CE0679
Name: metY Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Locus tag: CE0678
Name: metX Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31) |
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metY
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O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
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metX
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Homoserine O-acetyltransferase (EC 2.3.1.31)
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Position: -75
Score: 4.1 Sequence: TAGACTGATCGGTACT
Position: -52
Score: 5.3 Sequence: TAGACCAATCTGTCTA
Locus tag: CE2335
Name: cg2679 Funciton: Conserved hypothetical protein |
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cg2679
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Conserved hypothetical protein
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Position: -99
Score: 4.9 Sequence: TAGACCTCTCTGTCTA
Locus tag: CE2728
Name: CE2728 Funciton: Predicted permease protein |
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CE2728
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Predicted permease protein
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Position: -71
Score: 5.5 Sequence: TAGACAGATTGGTCTA
Position: -48
Score: 4.2 Sequence: AGTACCGATCAGTCTA
Locus tag: CE2334
Name: cg2678 Funciton: Predicted ABC transporter, substrate-binding protein
Locus tag: CE2333
Name: cg2677 Funciton: Predicted ABC transporter, permease protein 1
Locus tag: CE2332
Name: cg2676 Funciton: Predicted ABC transporter, permease protein 2
Locus tag: CE2331
Name: cg2675 Funciton: Predicted ABC transporter, ATP-binding protein
Locus tag: CE2330
Name: cg2674 Funciton: Conserved hypothetical protein |
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cg2678
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Predicted ABC transporter, substrate-binding protein
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cg2677
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Predicted ABC transporter, permease protein 1
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cg2676
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Predicted ABC transporter, permease protein 2
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cg2675
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Predicted ABC transporter, ATP-binding protein
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cg2674
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Conserved hypothetical protein
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Position: -281
Score: 4.4 Sequence: CCGACCACTCTGTCTA
Position: -247
Score: 5.1 Sequence: TAGACCGCTTGGTCTG
Position: -163
Score: 4.4 Sequence: TAGACCGTCCAGTCTA
Position: -46
Score: 4.6 Sequence: TAGACAGATCGGTACG
Locus tag: CE2644
Name: cysI Funciton: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Locus tag: CE2643
Name: cysX Funciton: Ferredoxin-like protein involved in electron transfer
Locus tag: CE2642
Name: cysH Funciton: Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Locus tag: CE2641
Name: cysD Funciton: Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
Locus tag: CE2640
Name: cysN Funciton: Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
Locus tag: CE2639
Name: cysY Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: CE2638
Name: cysZ Funciton: Sulfate transporter, CysZ-type |
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cysI
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Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
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cysX
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Ferredoxin-like protein involved in electron transfer
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cysH
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Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
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cysD
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Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4)
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cysN
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Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4)
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cysY
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Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
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cysZ
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Sulfate transporter, CysZ-type
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Position: -73
Score: 5.5 Sequence: TAGACAGCTTGGTCTA
Locus tag: CE1723
Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Locus tag: CE1722
Name: priA Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication |
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metK
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S-adenosylmethionine synthetase (EC 2.5.1.6)
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priA
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Helicase PriA essential for oriC/DnaA-independent DNA replication
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Position: -212
Score: 4.7 Sequence: TAGACTGGACGGTCTA
Position: -128
Score: 5 Sequence: CAGACCAAGCGGTCTA
Position: -94
Score: 4.4 Sequence: TAGACAGAGTGGTCGG
Locus tag: CE2645
Name: cysJ Funciton: Ferredoxin--NADP reductase (EC 1.18.1.2) |
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cysJ
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Ferredoxin--NADP reductase (EC 1.18.1.2)
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Position: -154
Score: 4.1 Sequence: CGAACCGGTTTGTCTA
Locus tag: CE2788
Name: mcbR Funciton: Methionine biosynthesis transcriptional regulator McbR, TetR family |
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mcbR
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Methionine biosynthesis transcriptional regulator McbR, TetR family
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Position: -94
Score: 4.7 Sequence: TAGACCGAGCTGTACA
Locus tag: CE0631
Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
Locus tag: CE0630
Name: metN Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: CE0629
Name: metI Funciton: Methionine ABC transporter permease protein |
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metQ
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Methionine ABC transporter substrate-binding protein
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metN
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Methionine ABC transporter ATP-binding protein
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metI
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Methionine ABC transporter permease protein
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Position: -110
Score: 4.9 Sequence: TGAACAGCTTGGTCTA
Locus tag: CE1289
Name: hom Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: CE1290
Name: thrB Funciton: Homoserine kinase (EC 2.7.1.39) |
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hom
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Homoserine dehydrogenase (EC 1.1.1.3)
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thrB
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Homoserine kinase (EC 2.7.1.39)
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Position: 1
Score: 5.3 Sequence: TGGACAGCTTGGTCTA
Locus tag: CE2343
Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48) |
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metB
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Cystathionine gamma-synthase (EC 2.5.1.48)
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Position: -148
Score: 4.7 Sequence: TAGACCGATCCGTCTG
Locus tag: CE2446
Name: cysK Funciton: Cysteine synthase (EC 2.5.1.47)
Locus tag: CE2447
Name: cysE Funciton: Serine acetyltransferase (EC 2.3.1.30) |
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cysK
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Cysteine synthase (EC 2.5.1.47)
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cysE
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Serine acetyltransferase (EC 2.3.1.30)
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Position: -157
Score: 4.8 Sequence: TAGACAATTCTGTCTG
Locus tag: CE2654
Name: cg3132 Funciton: Conserved hypothetical protein |
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cg3132
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Conserved hypothetical protein
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Position: -119
Score: 5 Sequence: TAGACTGTTCTGTCTA
Locus tag: CE1328
Name: fixB Funciton: Electron transfer flavoprotein, beta subunit
Locus tag: CE1329
Name: fixA Funciton: Electron transfer flavoprotein, alpha subunit
Locus tag: CE1330
Name: iscS Funciton: Cysteine desulfurase (EC 2.8.1.7) |
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fixB
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Electron transfer flavoprotein, beta subunit
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fixA
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Electron transfer flavoprotein, alpha subunit
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iscS
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Cysteine desulfurase (EC 2.8.1.7)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |