Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of McbR in Corynebacterium amycolatum SK46

Properties
Regulator type: Transcription factor
TF locus tag: CORAM0001_2083
Regulator family: TetR
Regulation mode: repressor
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine; S-adenosylhomocysteine
Regulog: McbR - Corynebacteriaceae
Statistics of regulated genes:
- Genes 20
- Operons 13
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 162 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -205
Score: 5.4
Sequence: TAGACCAATCGGTCTA
Position: -170
Score: 4.8
Sequence: TAGACAAACTGGTCTA
Locus tag: CORAM0001_1360
Name: cysZ
Funciton: Sulfate transporter, CysZ-type
CORAM0001_1360
cysZ
Sulfate transporter, CysZ-type
Position: -22
Score: 4.3
Sequence: CGGACTAAGTAGTCTA
Locus tag: CORAM0001_0290
Name: metX
Funciton: Homoserine O-acetyltransferase (EC 2.3.1.31)
CORAM0001_0290
metX
Homoserine O-acetyltransferase (EC 2.3.1.31)
Position: -19
Score: 4.6
Sequence: TAGACTAAGGTGTCTA
Locus tag: CORAM0001_0986
Name: metH
Funciton: 5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
CORAM0001_0986
metH
5-methyltetrahydrofolate-homocysteine methyltransferase (EC 2.1.1.13)
Position: -163
Score: 4
Sequence: TATACGGTTCGGTCTG
Position: -65
Score: 4.6
Sequence: TAGACAGGTCTGTTCA
Locus tag: CORAM0001_2013
Name: CE2728
Funciton: Predicted permease protein
CORAM0001_2013
CE2728
Predicted permease protein
Position: -19
Score: 4.8
Sequence: TGGACTAAGCTGTCTA
Locus tag: CORAM0001_0958
Name: cg1739
Funciton: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
Locus tag: CORAM0001_0957
Name: cg1739
Funciton: GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
CORAM0001_0958
cg1739
GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
CORAM0001_0957
cg1739
GMP synthase-Glutamine amidotransferase domain (EC 6.3.5.2)
Position: -73
Score: 5
Sequence: TAGACAGCTTGGTTCA
Locus tag: CORAM0001_0291
Name: metY
Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
CORAM0001_0291
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Position: -113
Score: 4.7
Sequence: CAGACTGGTCGGTCTA
Position: -77
Score: 5.1
Sequence: TAGACCAAACGGTCTA
Locus tag: CORAM0001_1359
Name: cysI
Funciton: Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
CORAM0001_1359
cysI
Ferredoxin--sulfite reductase, actinobacterial type (EC 1.8.7.1)
Position: -98
Score: 4.8
Sequence: TGAACCGCTTGGTCTA
Locus tag: CORAM0001_0910
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Locus tag: CORAM0001_0911
Name: priA
Funciton: Helicase PriA essential for oriC/DnaA-independent DNA replication
CORAM0001_0910
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
CORAM0001_0911
priA
Helicase PriA essential for oriC/DnaA-independent DNA replication
Position: -137
Score: 5.2
Sequence: TAGACCACGTGGTCTA
Position: -49
Score: 4.8
Sequence: TAGACAACTCGGTACA
Position: -28
Score: 4.9
Sequence: TAGACAGTATTGTCTA
Locus tag: CORAM0001_0385
Name: ssuR
Funciton: Sulphonate sulphur utilization transcriptional regulator SsuR, ROK family
CORAM0001_0385
ssuR
Sulphonate sulphur utilization transcriptional regulator SsuR, ROK family
Position: -134
Score: 4.8
Sequence: TAGACAATACTGTCTA
Position: -113
Score: 4.8
Sequence: TGTACCGAGTTGTCTA
Position: -25
Score: 5.2
Sequence: TAGACCACGTGGTCTA
Locus tag: CORAM0001_0384
Name: ssuD
Funciton: Alkanesulfonate monooxygenase
Locus tag: CORAM0001_0383
Name: ssuI
Funciton: Predicted flavin reductase
Locus tag: CORAM0001_0382
Name: seuA
Funciton: coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductase
CORAM0001_0384
ssuD
Alkanesulfonate monooxygenase
CORAM0001_0383
ssuI
Predicted flavin reductase
CORAM0001_0382
seuA
coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductase
Position: -98
Score: 4.9
Sequence: TAGACCAGTTTGTCTA
Position: -63
Score: 5.4
Sequence: TAGACCGATTGGTCTA
Locus tag: CORAM0001_1361
Name: cysJ
Funciton: Ferredoxin--NADP reductase (EC 1.18.1.2)
CORAM0001_1361
cysJ
Ferredoxin--NADP reductase (EC 1.18.1.2)
Position: -103
Score: 3.9
Sequence: TAGACGAACTGGTCTG
Locus tag: CORAM0001_2226
Name: cysK
Funciton: Cysteine synthase (EC 2.5.1.47)
Locus tag: CORAM0001_2227
Name: cysE
Funciton: Serine acetyltransferase (EC 2.3.1.30)
CORAM0001_2226
cysK
Cysteine synthase (EC 2.5.1.47)
CORAM0001_2227
cysE
Serine acetyltransferase (EC 2.3.1.30)
Position: -70
Score: 5
Sequence: AAGACAGCTTGGTCTA
Locus tag: CORAM0001_0284
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
Locus tag: CORAM0001_0283
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: CORAM0001_0282
Name: metI
Funciton: Methionine ABC transporter permease protein
CORAM0001_0284
metQ
Methionine ABC transporter substrate-binding protein
CORAM0001_0283
metN
Methionine ABC transporter ATP-binding protein
CORAM0001_0282
metI
Methionine ABC transporter permease protein
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