Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TPP in Clostridium botulinum A str. ATCC 3502

Properties
Regulator type: RNA regulatory element
Name: TPP
RFAM: RF00059
Regulation mode:
Biological process: Thiamine biosynthesis
Effector: Thiamine pyrophosphate
Regulog: TPP - Clostridiaceae
Under regulation:
- Genes 9
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -160
Score: 78.2
Sequence: TTAAGTGCTAGGGGT...
Locus tag: CBO0556
Name: thiT
Funciton: Substrate-specific component ThiT of thiamin ECF transporter
thiT
Substrate-specific component ThiT of thiamin ECF transporter

Position: -409
Score: 71.3
Sequence: CCTTATGTTGTGGGG...
Locus tag: CBO0451
Name: thiD
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
Locus tag: CBO0450
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: CBO0449
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiD
Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)

Position: -191
Score: 75.7
Sequence: TATGTAAATGCAGGG...
Locus tag: CBO2913
Name: purF2
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: CBO2911
Name: thiC
Funciton: Thiamine biosynthesis protein ThiC
Locus tag: CBO2910
Name: COG0011
Funciton: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family
purF2
Amidophosphoribosyltransferase (EC 2.4.2.14)
thiC
Thiamine biosynthesis protein ThiC
COG0011
Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family

Position: -410
Score: 54.7
Sequence: AATTTTTCAAAAGGG...
Locus tag: CBO2254
Name: thiW
Funciton: Substrate-specific component ThiW of predicted thiazole ECF transporter
Locus tag: CBO2253
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiW
Substrate-specific component ThiW of predicted thiazole ECF transporter
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD