Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Vibrio splendidus LGP32

Properties
Regulator type: Transcription factor
TF locus tag: VS_1088
Regulator family: LacI
Regulation mode: repressor
Biological process: Purine metabolism
Effector: Hypoxanthine; Guanine
Regulog: PurR - Vibrionales
Statistics of regulated genes:
- Genes 20
- Operons 16
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 149 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -90
Score: 6.1
Sequence: ACGAAAACGTTTGCTT
Locus tag: VS_0629
Name: guaA
Funciton: GMP synthase (EC 6.3.5.2)
guaA
GMP synthase (EC 6.3.5.2)

Position: -116
Score: 5.4
Sequence: TAGCAATCGTTTGCTT
Locus tag: VS_1205
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)

Position: -88
Score: 5.7
Sequence: ACGCAAACGTTTTCCT
Locus tag: VS_3120
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: VS_3121
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -81
Score: 5.6
Sequence: GCGCAAACGTTTGCTC
Locus tag: VS_2318
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: VS_2319
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)

Position: -90
Score: 5.2
Sequence: ACGCAAACGATTGCGC
Locus tag: VS_2034
Name: purB
Funciton: Adenylosuccinate lyase (EC 4.3.2.2)
purB
Adenylosuccinate lyase (EC 4.3.2.2)

Position: -48
Score: 5.6
Sequence: ACGCAAACGTTTACGT
Locus tag: VS_II0809
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)

Position: -92
Score: 5.4
Sequence: TAGCAAACGTTTGCTA
Locus tag: VS_2030
Name: gsk
Funciton: Inosine-guanosine kinase (EC 2.7.1.73)
gsk
Inosine-guanosine kinase (EC 2.7.1.73)

Position: -237
Score: 4.2
Sequence: TGCCAAACGATTGCGC
Locus tag: VS_2951
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Locus tag: VS_2952
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)

Position: -203
Score: 5.1
Sequence: AAGTAAACGATTGCCT
Locus tag: VS_0757
Name: ushA
Funciton: UDP-sugar hydrolase (EC 3.6.1.45); 5'-nucleotidase (EC 3.1.3.5)
ushA
UDP-sugar hydrolase (EC 3.6.1.45); 5'-nucleotidase (EC 3.1.3.5)

Position: -192
Score: 5.9
Sequence: ACGCAAACGGTTGCTT
Locus tag: VS_0664
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

Position: -83
Score: 5.9
Sequence: GCGCAAACGTTTGCTT
Locus tag: VS_1717
Name: purT
Funciton: Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)
purT
Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)

Position: -145
Score: 5.4
Sequence: ACGATAACGTTTGCTT
Locus tag: VS_1422
Name: pyrD
Funciton: Dihydroorotate dehydrogenase (EC 1.3.3.1)
pyrD
Dihydroorotate dehydrogenase (EC 1.3.3.1)

Position: -89
Score: 5.5
Sequence: GAGCAAACGTTTGCGC
Locus tag: VS_2317
Name: upp
Funciton: Uracil phosphoribosyltransferase (EC 2.4.2.9)
upp
Uracil phosphoribosyltransferase (EC 2.4.2.9)

Position: -96
Score: 6.2
Sequence: AAGCAAACGTTTGCTT
Locus tag: VS_0889
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)

Position: -63
Score: 6
Sequence: AAGAAAACGTTTGCGT
Locus tag: VS_0907
Name: cvpA
Funciton: Colicin V production protein
Locus tag: VS_0908
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
cvpA
Colicin V production protein
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)

Position: -73
Score: 5.8
Sequence: ACGGAAACGTTTGCTT
Locus tag: VS_2373
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD