Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of SiaR in Haemophilus influenzae Rd KW20

Properties
Regulator type: Transcription factor
TF locus tag: HI0143
Regulator family: RpiR
Regulation mode: repressor (activator)
Biological process: Sialic acid utilization
Effector: Glucosamine-6-phosphate
Regulog: SiaR - Pasteurellales
Statistics of regulated genes:
- Genes 9
- Operons 2
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 23 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -163
Score: 4.8
Sequence: TATGAAAAAACACTTCAAA
Locus tag: HI0145
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: HI0144
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: HI0143
Name: siaR
Funciton: Sialic acid utilization regulator, RpiR family
Locus tag: HI0142
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: HI0141
Name: nagB
Funciton: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
Locus tag: HI0140
Name: nagA
Funciton: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
nanE
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanK
N-acetylmannosamine kinase (EC 2.7.1.60)
siaR
Sialic acid utilization regulator, RpiR family
nanA
N-acetylneuraminate lyase (EC 4.1.3.3)
nagB
Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
nagA
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)

Position: -205
Score: 4.8
Sequence: TTTGAAGTGTTTTTTCATA
Locus tag: HI0146
Name: siaP
Funciton: Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
Locus tag: HI0147
Name: siaT
Funciton: TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
Locus tag: HI0148
Name: nanM
Funciton: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
siaP
Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
siaT
TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
nanM
Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
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