Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CodY in Bacillus licheniformis DSM 13

Properties
Regulator type: Transcription factor
TF locus tag: BLi01837
Regulator family: CodY
Regulation mode:
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Regulog: CodY - Bacillales
Statistics of regulated genes:
- Genes 98
- Operons 59
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 445 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -418
Score: 4.2
Sequence: ATTTTTTTGTCAATT
Locus tag: BLi00401
Name: srfAA
Funciton: Surfactin synthetase subunit 1
Locus tag: BLi00402
Name: srfAB
Funciton: Surfactin synthetase subunit 2
Locus tag: BLi00403
Name: srfAC
Funciton: Bacitracin synthetase 3 (BA3)( EC:5.1.1.11,EC:5.1.1.13 )
Locus tag: BLi00404
Name: srfAD
Funciton: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
srfAA
Surfactin synthetase subunit 1
srfAB
Surfactin synthetase subunit 2
srfAC
Bacitracin synthetase 3 (BA3)( EC:5.1.1.11,EC:5.1.1.13 )
srfAD
Surfactin synthetase thioesterase subunit (EC 3.1.2.-)

Position: -74
Score: 4.8
Sequence: TATTTTTTAAAAATT
Locus tag: BLi03119
Name: acsA
Funciton: Acetyl-coenzyme A synthetase (EC 6.2.1.1)
acsA
Acetyl-coenzyme A synthetase (EC 6.2.1.1)

Position: -81
Score: 4.4
Sequence: TTTTTTCTAATAATT
Locus tag: BLi02277
Name: yoyD
Funciton: Hypothetical protein
Locus tag: BLi02278
Name: yodF
Funciton: SSS family solute:sodium (Na+) symporter
yoyD
Hypothetical protein
yodF
SSS family solute:sodium (Na+) symporter

Position: -194
Score: 4.8
Sequence: TATATTCAGAAAATA
Locus tag: BLi03086
Name: ackA
Funciton: Acetate kinase (EC 2.7.2.1)
ackA
Acetate kinase (EC 2.7.2.1)

Position: -151
Score: 4.7
Sequence: ATTATTCAGACAATT
Locus tag: BLi04129
Name: pelB
Funciton: Pectate lyase precursor (EC 4.2.2.2)
pelB
Pectate lyase precursor (EC 4.2.2.2)

Position: -50
Score: 4.9
Sequence: AATTGTCATAAAATT
Locus tag: BLi01088
Name: yhaA
Funciton: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
yhaA
N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)

Position: -47
Score: 4.9
Sequence: AATTATCAGATAATT
Locus tag: BLi01291
Name: yjcL
Funciton: Putative integral membrane protein
yjcL
Putative integral membrane protein

Position: -103
Score: 5
Sequence: ATTTTTTTGAAAATT
Locus tag: BLi01176
Name: glnB
Funciton: Nitrogen regulatory protein P-II
Locus tag: BLi01175
Name: amt
Funciton: Ammonium transporter
glnB
Nitrogen regulatory protein P-II
amt
Ammonium transporter

Position: -114
Score: 4.7
Sequence: ACTTTTCATAAAATT
Locus tag: BLi01423
Name: ispA
Funciton: S8 family serine protease precursor (EC 3.4.21.-)
ispA
S8 family serine protease precursor (EC 3.4.21.-)

Position: -65
Score: 4.6
Sequence: AATATTTAAAAAATA
Locus tag: BLi01009
Name: citR
Funciton: Transcriptional regulator of citrate synthase, LysR family
citR
Transcriptional regulator of citrate synthase, LysR family

Position: -39
Score: 4.7
Sequence: ATTTATCAGAATATT
Locus tag: BLi01752
Name: ylmA
Funciton: Putative ABC transporter, ATP-binding protein
ylmA
Putative ABC transporter, ATP-binding protein

Position: -49
Score: 4.8
Sequence: AATTTTCAGAACATT
Locus tag: BLi00421
Name: rocR
Funciton: Transcriptional activator of arginine utilization, Fis family
rocR
Transcriptional activator of arginine utilization, Fis family

Position: -225
Score: 4.5
Sequence: AAATGTCTGATAATT
Locus tag: BLi03062
Name: citZ
Funciton: Citrate synthase (si) (EC 2.3.3.1)
Locus tag: BLi03061
Name: icd
Funciton: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
Locus tag: BLi03060
Name: mdh
Funciton: Malate dehydrogenase (EC 1.1.1.37)
citZ
Citrate synthase (si) (EC 2.3.3.1)
icd
Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)
mdh
Malate dehydrogenase (EC 1.1.1.37)

Position: -74
Score: 4.7
Sequence: AATTGTTTGAAAAAT
Locus tag: BLi02408
Name: ndk
Funciton: Nucleoside diphosphate kinase (EC 2.7.4.6)
ndk
Nucleoside diphosphate kinase (EC 2.7.4.6)

Position: -88
Score: 4.7
Sequence: AATTGTCAAACAATT
Locus tag: BLi03206
Name: ytkC
Funciton: Hypothetical membrane protein
ytkC
Hypothetical membrane protein

Position: -151
Score: 4.9
Sequence: AATTTTCTAAAATTT
Position: -132
Score: 4.5
Sequence: ATATTTTTGAAAATT
Locus tag: BLi02995
Name: yslB
Funciton: Predicted hydrocarbon binding protein (V4R domain)
yslB
Predicted hydrocarbon binding protein (V4R domain)

Position: -184
Score: 4.5
Sequence: AATTTTCAAAAATAT
Position: -165
Score: 4.9
Sequence: AAATTTTAGAAAATT
Locus tag: BLi02994
Name: sdhC
Funciton: Succinate dehydrogenase, cytochrome b subunit
Locus tag: BLi02993
Name: sdhA
Funciton: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)
Locus tag: BLi02992
Name: sdhB
Funciton: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)
sdhC
Succinate dehydrogenase, cytochrome b subunit
sdhA
Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)
sdhB
Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)

Position: -29
Score: 4.9
Sequence: TATTTTCTGAAAAAT
Locus tag: BLi04226
Name: null
Funciton: Hypothetical protein
Hypothetical protein

Position: -163
Score: 4.8
Sequence: AATATTCTGAATAAT
Locus tag: BLi02256
Name: yocR
Funciton: Putative sodium-dependent transporter
yocR
Putative sodium-dependent transporter

Position: -66
Score: 4.8
Sequence: ATTATTCAGAATATT
Locus tag: BLi02258
Name: yocS
Funciton: Sodium-dependent transporter
yocS
Sodium-dependent transporter

Position: -217
Score: 4.5
Sequence: ATTTATCTAAATATT
Locus tag: BLi01028
Name: yhdT
Funciton: Hemolysins and related proteins containing CBS domains
yhdT
Hemolysins and related proteins containing CBS domains

Position: -112
Score: 4.5
Sequence: AATATTTAGATAAAT
Locus tag: BLi01027
Name: cueR
Funciton: Transcriptional regulator, MerR family
cueR
Transcriptional regulator, MerR family

Position: -36
Score: 5
Sequence: AATTTTTAGAAAATA
Locus tag: BLi00013
Name: yaaC
Funciton: Conserved hypothetical protein
yaaC
Conserved hypothetical protein

Position: -165
Score: 4.6
Sequence: CATTTTCAGAAAATA
Locus tag: BLi03329
Name: kapD
Funciton: KapD, inhibitor of KinA pathway to sporulation
kapD
KapD, inhibitor of KinA pathway to sporulation

Position: -132
Score: 4.4
Sequence: AAAATTCAGAAATTT
Locus tag: BLi03466
Name: fadN
Funciton: Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)
Locus tag: BLi03465
Name: fadA
Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Locus tag: BLi03464
Name: fadE
Funciton: Acyl-CoA dehydrogenase (EC 1.3.99.3)
fadN
Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)
fadA
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
fadE
Acyl-CoA dehydrogenase (EC 1.3.99.3)

Position: -93
Score: 4.7
Sequence: ATTTTTTAAAAAATT
Locus tag: BLi01078
Name: hpr
Funciton: Transcriptional repressor of sporulation and extracellular protein, MarR family
hpr
Transcriptional repressor of sporulation and extracellular protein, MarR family

Position: -167
Score: 5.1
Sequence: AATATTCTGAATATT
Locus tag: BLi00730
Name: gatC
Funciton: Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7)
Locus tag: BLi00731
Name: gatA
Funciton: Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7)
Locus tag: BLi00732
Name: gatB
Funciton: Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7)
gatC
Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7)
gatA
Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7)
gatB
Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7)

Position: -205
Score: 5.3
Sequence: AATTTTTAGAAAATT
Locus tag: BLi01119
Name: comK
Funciton: Competence transcription factor
comK
Competence transcription factor

Position: -192
Score: 4.7
Sequence: AATTGTCTAATAATT
Locus tag: BLi02962
Name: dat
Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
dat
Branched-chain amino acid aminotransferase (EC 2.6.1.42)

Position: -171
Score: 4.7
Sequence: AATTTTCTCACAATT
Locus tag: BLi02046
Name: sspO
Funciton: Small, acid-soluble spore protein O
Locus tag: BLi02045
Name: sspP
Funciton: Small, acid-soluble spore protein P
sspO
Small, acid-soluble spore protein O
sspP
Small, acid-soluble spore protein P

Position: -60
Score: 4.6
Sequence: TATTTTTTAAATATT
Locus tag: BLi01010
Name: citA
Funciton: Citrate synthase (si) (EC 2.3.3.1)
citA
Citrate synthase (si) (EC 2.3.3.1)

Position: -53
Score: 4.8
Sequence: AATATACTGAAAATT
Locus tag: BLi00191
Name: murQ
Funciton: N-acetylmuramic acid 6-phosphate etherase (EC 4.2.-.-)
Locus tag: BLi00190
Name: murR
Funciton: Transcriptional regulator of muropeptide rescue pathway operon, RpiR family
Locus tag: BLi00189
Name: ybbF
Funciton: PTS system, IIB component (EC 2.7.1.69) / PTS system, IIC component (EC 2.7.1.69)
Locus tag: BLi00188
Name: amiE
Funciton: Amidase of hydrolyzes the N-acetylmuramyl- L-Ala bond of MurNAc peptides
Locus tag: BLi00187
Name: nagZ
Funciton: Beta--N-acetylglucosaminidase
Locus tag: BLi00186
Name: ybbC
Funciton: Hypothetical protein
murQ
N-acetylmuramic acid 6-phosphate etherase (EC 4.2.-.-)
murR
Transcriptional regulator of muropeptide rescue pathway operon, RpiR family
ybbF
PTS system, IIB component (EC 2.7.1.69) / PTS system, IIC component (EC 2.7.1.69)
amiE
Amidase of hydrolyzes the N-acetylmuramyl- L-Ala bond of MurNAc peptides
nagZ
Beta--N-acetylglucosaminidase
ybbC
Hypothetical protein

Position: -68
Score: 4.6
Sequence: TATTTTCTGAAAATG
Locus tag: BLi03330
Name: yuxJ
Funciton: MFS family major facilitator transporter
Locus tag: BLi03331
Name: pbpD
Funciton: Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)
Locus tag: BLi03332
Name: yuxK
Funciton: Possible thiol-disulphide dehydrogenase
yuxJ
MFS family major facilitator transporter
pbpD
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)
yuxK
Possible thiol-disulphide dehydrogenase

Position: -61
Score: 4.5
Sequence: ATTTGTTAGAATATT
Locus tag: BLi01392
Name: dppA
Funciton: D-aminopeptidase (EC 3.4.11.-)
Locus tag: BLi01393
Name: dppB
Funciton: Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)
Locus tag: BLi01394
Name: dppC
Funciton: Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)
Locus tag: BLi01395
Name: dppD
Funciton: Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)
Locus tag: BLi01396
Name: dppE
Funciton: Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)
dppA
D-aminopeptidase (EC 3.4.11.-)
dppB
Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)
dppC
Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)
dppD
Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)
dppE
Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)

Position: -56
Score: 5
Sequence: AATTATTAGAAAATT
Locus tag: BLi03425
Name: null
Funciton: Sodium/proline symporter
Sodium/proline symporter

Position: -289
Score: 5.1
Sequence: AATATTCAGAATATT
Locus tag: BLi00728
Name: opuE
Funciton: Sodium/proline symporter
opuE
Sodium/proline symporter

Position: -97
Score: 4.6
Sequence: AATATTCTGTAAATA
Locus tag: BLi02315
Name: ilvA
Funciton: Threonine dehydratase biosynthetic (EC 4.3.1.19)
ilvA
Threonine dehydratase biosynthetic (EC 4.3.1.19)

Position: -43
Score: 4.8
Sequence: TATTTTCTGAAAAGT
Locus tag: BLi03892
Name: spoIIQ
Funciton: Stage II sporulation protein related to metaloproteases (SpoIIQ)
spoIIQ
Stage II sporulation protein related to metaloproteases (SpoIIQ)

Position: -51
Score: 4.8
Sequence: AATATTCAGAATATA
Locus tag: BLi02324
Name: ilvD
Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvD
Dihydroxy-acid dehydratase (EC 4.2.1.9)

Position: -43
Score: 4.5
Sequence: AATTATCAGATATTT
Locus tag: BLi02446
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
serA
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

Position: -96
Score: 4.8
Sequence: AATTTTTAAAAAATA
Locus tag: BLi03120
Name: acuA
Funciton: Acetyltransferase AcuA, acetyl-CoA synthetase inhibitor
Locus tag: BLi03121
Name: acuB
Funciton: Component of the acetoin degradation regulation pathway
Locus tag: BLi03122
Name: acuC
Funciton: NAD-independent protein deacetylase AcuC
acuA
Acetyltransferase AcuA, acetyl-CoA synthetase inhibitor
acuB
Component of the acetoin degradation regulation pathway
acuC
NAD-independent protein deacetylase AcuC

Position: -78
Score: 4.7
Sequence: AATTGTGAGAAAATT
Locus tag: BLi02047
Name: citB
Funciton: Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99)
citB
Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99)

Position: -57
Score: 4.7
Sequence: AAAATTCTGAATATT
Locus tag: BLi00656
Name: amyS
Funciton: Cytoplasmic alpha-amylase (EC 3.2.1.1)
amyS
Cytoplasmic alpha-amylase (EC 3.2.1.1)

Position: -91
Score: 4.7
Sequence: AAATTTATGAAAATT
Locus tag: BLi04156
Name: glpQ
Funciton: Glycerophosphoryl diester phosphodiesterase, periplasmic (EC 3.1.4.46)
glpQ
Glycerophosphoryl diester phosphodiesterase, periplasmic (EC 3.1.4.46)

Position: -83
Score: 4.6
Sequence: AATTTTCAGACAAAA
Locus tag: BLi00778
Name: yfmB
Funciton: Hypothetical protein
yfmB
Hypothetical protein

Position: -44
Score: 4.8
Sequence: AATATTCAGAAGATT
Locus tag: BLi03321
Name: alaR
Funciton: Transcriptional regulator of alanine metabolism, Lrp/AsnC family
Locus tag: BLi03320
Name: alaT
Funciton: Aspartate aminotransferase (EC 2.6.1.1)
alaR
Transcriptional regulator of alanine metabolism, Lrp/AsnC family
alaT
Aspartate aminotransferase (EC 2.6.1.1)

Position: -111
Score: 4.6
Sequence: AATTTTTATAAAAAT
Locus tag: BLi03479
Name: yusZ
Funciton: Oxidoreductase, short-chain dehydrogenase/reductase (EC 1.1.1.-)
yusZ
Oxidoreductase, short-chain dehydrogenase/reductase (EC 1.1.1.-)

Position: -52
Score: 4.6
Sequence: AACTTTCAGAATATT
Locus tag: BLi00817
Name: glyP
Funciton: Sodium/glycine symporter GlyP
glyP
Sodium/glycine symporter GlyP

Position: -98
Score: 4.5
Sequence: TATTATTTGAAAATA
Locus tag: BLi03198
Name: gltZ
Funciton: Proton/glutamate symport protein @ Sodium/glutamate symport protein
gltZ
Proton/glutamate symport protein @ Sodium/glutamate symport protein

Position: -193
Score: 4.5
Sequence: ACTTTTCTCAAAATT
Locus tag: BLi00175
Name: pdaB
Funciton: Probable polysaccharide deacetylase
pdaB
Probable polysaccharide deacetylase

Position: -241
Score: 4.4
Sequence: TATTATAAGAATATT
Locus tag: BLi00220
Name: ybxG
Funciton: Amino acid permease
ybxG
Amino acid permease

Position: -155
Score: 4.3
Sequence: AAGTTTCTGAAAAAA
Locus tag: BLi00373
Name: putB
Funciton: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase)
Locus tag: BLi00374
Name: putC
Funciton: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
putB
Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase)
putC
Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)

Position: -85
Score: 4.5
Sequence: ATTAGTCTAAAAATT
Locus tag: BLi00375
Name: putP
Funciton: Proline/sodium symporter (TC 2.A.21.2.1)
Locus tag: BLi00376
Name: putR
Funciton: Transcriptional regulator of proline utilization
putP
Proline/sodium symporter (TC 2.A.21.2.1)
putR
Transcriptional regulator of proline utilization

Position: -124
Score: 4.6
Sequence: AATTTTCAATATATT
Locus tag: BLi01100
Name: gltT
Funciton: Proton/sodium-glutamate symport protein
gltT
Proton/sodium-glutamate symport protein

Position: -165
Score: 4.8
Sequence: AATTTTCTGTCAATT
Locus tag: BLi03101
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: BLi03100
Name: thiI
Funciton: Thiamine biosynthesis protein ThiI
iscS
Cysteine desulfurase (EC 2.8.1.7)
thiI
Thiamine biosynthesis protein ThiI

Position: -164
Score: 4
Sequence: AACAATCAGAATATT
Locus tag: BLi01289
Name: metI
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: BLi01290
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
metI
Cystathionine gamma-synthase (EC 2.5.1.48)
metC
Cystathionine beta-lyase (EC 4.4.1.8)

Position: -30
Score: 4.3
Sequence: AATAGACTGAATATT
Locus tag: BLi01233
Name: oppB
Funciton: Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)
Locus tag: BLi01234
Name: oppC
Funciton: Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)
Locus tag: BLi01235
Name: oppD
Funciton: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)
Locus tag: BLi01236
Name: oppF
Funciton: Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)
oppB
Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)
oppC
Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)
oppD
Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)
oppF
Oligopeptide transport ATP-binding protein OppF (TC 3.A.1.5.1)

Position: -35
Score: 4.9
Sequence: TATTATCAGAAAATT
Locus tag: BLi03391
Name: yuiA
Funciton: Conserved hypothetical protein
Locus tag: BLi03390
Name: yuiB
Funciton: Hypothetical membrane protein
Locus tag: BLi03389
Name: yuiC
Funciton: Cell wall-binding protein
yuiA
Conserved hypothetical protein
yuiB
Hypothetical membrane protein
yuiC
Cell wall-binding protein

Position: -114
Score: 4.8
Sequence: AATGTTCTGAAAATT
Locus tag: BLi00422
Name: rocD
Funciton: Ornithine aminotransferase (EC 2.6.1.13)
Locus tag: BLi00423
Name: rocE
Funciton: Arginine permease RocE
Locus tag: BLi00424
Name: rocF
Funciton: Arginase (EC 3.5.3.1)
rocD
Ornithine aminotransferase (EC 2.6.1.13)
rocE
Arginine permease RocE
rocF
Arginase (EC 3.5.3.1)
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