Regulon of NtrC in Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Properties
Regulator type:	Transcription factor
TF locus tag:	KPN_04176
Regulator family:	Fis
Regulation mode:	activator (repressor)
Biological process:	Nitrogen assimilation
Effector:	Phosphorylated NtrB, signal histidine kinase
Regulog:	NtrC - Enterobacteriales
Statistics of regulated genes:
- Genes	38
- Operons	11
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 130 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - NtrC
By TF family - Fis
By effector - Phosphorylated NtrB, signal histidine kinase
By pathway - Nitrogen assimilation

Regulated operons
	Locus Tag	Name	Function
Position: -305 Score: 4.1 Sequence: CGCGCCAAAAAAGGGCA Locus tag: KPN_01221 Name: astC Funciton: Succinylornithine transaminase (EC 2.6.1.81) Locus tag: KPN_01222 Name: astA Funciton: Arginine N-succinyltransferase (EC 2.3.1.109) Locus tag: KPN_01223 Name: astD Funciton: Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) Locus tag: KPN_01224 Name: astB Funciton: Succinylarginine dihydrolase (EC 3.5.3.23) Locus tag: KPN_01225 Name: astE Funciton: Succinylglutamate desuccinylase (EC 3.5.1.96)
	KPN_01221	astC	Succinylornithine transaminase (EC 2.6.1.81)
	KPN_01222	astA	Arginine N-succinyltransferase (EC 2.3.1.109)
	KPN_01223	astD	Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71)
	KPN_01224	astB	Succinylarginine dihydrolase (EC 3.5.3.23)
	KPN_01225	astE	Succinylglutamate desuccinylase (EC 3.5.1.96)
Position: -39 Score: 6 Sequence: TGCACTAAATTGGTGCA Locus tag: KPN_04177 Name: ntrB Funciton: Nitrogen regulation protein NR(II) (EC 2.7.3.-) Locus tag: KPN_04176 Name: ntrC Funciton: Nitrogen regulation protein NR(I), Fis family
	KPN_04177	ntrB	Nitrogen regulation protein NR(II) (EC 2.7.3.-)
	KPN_04176	ntrC	Nitrogen regulation protein NR(I), Fis family
Position: -251 Score: 6 Sequence: TGCACCAAAATGGTGCT Position: -219 Score: 5.2 Sequence: AGCACTATTTTGGTGCA Locus tag: KPN_04178 Name: glnA Funciton: Glutamine synthetase type I (EC 6.3.1.2)
	KPN_04178	glnA	Glutamine synthetase type I (EC 6.3.1.2)
Position: -181 Score: 5.3 Sequence: TGCACCGTTGTGGTGCA Locus tag: KPN_00413 Name: glnK Funciton: nitrogen regulatory protein P-II Locus tag: KPN_00414 Name: amtB Funciton: Ammonium transporter
	KPN_00413	glnK	nitrogen regulatory protein P-II
	KPN_00414	amtB	Ammonium transporter
Position: -171 Score: 4.6 Sequence: CGCGCTATTTTGGTGCA Locus tag: KPN_00681 Name: gltI Funciton: Glutamate-aspartate ABC transporter, substrate-binding component Locus tag: KPN_00680 Name: gltJ Funciton: Glutamate-aspartate ABC transporter, transmembrane component 1 Locus tag: KPN_00679 Name: gltK Funciton: Glutamate-aspartate ABC transporter, transmembrane component 2 Locus tag: KPN_00678 Name: gltL Funciton: Glutamate-aspartate ABC transporter, ATP-binding component
	KPN_00681	gltI	Glutamate-aspartate ABC transporter, substrate-binding component
	KPN_00680	gltJ	Glutamate-aspartate ABC transporter, transmembrane component 1
	KPN_00679	gltK	Glutamate-aspartate ABC transporter, transmembrane component 2
	KPN_00678	gltL	Glutamate-aspartate ABC transporter, ATP-binding component
Position: -215 Score: 5.3 Sequence: TGCCCCAAAAGGGTGCA Position: -185 Score: 4 Sequence: TGGATCATTTCAGTGCA Locus tag: KPN_02699 Name: hisJ Funciton: Histidine ABC transporter, substrate-binding component Locus tag: KPN_02698 Name: hisQ Funciton: Histidine ABC transporter, transmembrane component 1 Locus tag: KPN_02697 Name: hisM Funciton: Histidine ABC transporter, transmembrane component 2 Locus tag: KPN_02696 Name: hisP Funciton: Histidine ABC transporter, ATP-binding component
	KPN_02699	hisJ	Histidine ABC transporter, substrate-binding component
	KPN_02698	hisQ	Histidine ABC transporter, transmembrane component 1
	KPN_02697	hisM	Histidine ABC transporter, transmembrane component 2
	KPN_02696	hisP	Histidine ABC transporter, ATP-binding component
Position: -172 Score: 4.2 Sequence: CGCACCAAAATGACGCC Position: -159 Score: 5 Sequence: CGCCCCACCATGGTGCA Locus tag: KPN_00840 Name: glnH Funciton: Glutamine ABC transporter, substrate-binding component Locus tag: KPN_00839 Name: glnP Funciton: Glutamine ABC transporter, transmembrane component Locus tag: KPN_00838 Name: glnQ Funciton: Glutamine ABC transporter, ATP-binding component
	KPN_00840	glnH	Glutamine ABC transporter, substrate-binding component
	KPN_00839	glnP	Glutamine ABC transporter, transmembrane component
	KPN_00838	glnQ	Glutamine ABC transporter, ATP-binding component
Position: -206 Score: 5 Sequence: TGCACCGTTGTAGTGCG Locus tag: KPN_02437 Name: nac Funciton: Nitrogen assimilation transcriptional regulator, LysR family
	KPN_02437	nac	Nitrogen assimilation transcriptional regulator, LysR family
Position: -211 Score: 3.9 Sequence: GGCGCCAGCGTGGTGCT Position: -193 Score: 5.1 Sequence: TGCATTATTATGGTGCA Locus tag: KPN_01766 Name: EAM_0872 Funciton: Predicted ABC transporter, substrate-binding component Locus tag: KPN_01765 Name: EAM_0873 Funciton: Predicted ABC transporter, permease component 1 Locus tag: KPN_01764 Name: EAM_0874 Funciton: Predicted ABC transporter, permease component 2 Locus tag: KPN_01763 Name: EAM_0875 Funciton: Predicted ABC transporter, ATP-binding component Locus tag: KPN_01762 Name: pucG Funciton: Serine--pyruvate aminotransferase (EC 2.6.1.51) / L-alanine:glyoxylate aminotransferase (EC 2.6.1.44) Locus tag: KPN_01761 Name: amaB Funciton: N-carbamoyl-L-amino acid hydrolase
	KPN_01766	EAM_0872	Predicted ABC transporter, substrate-binding component
	KPN_01765	EAM_0873	Predicted ABC transporter, permease component 1
	KPN_01764	EAM_0874	Predicted ABC transporter, permease component 2
	KPN_01763	EAM_0875	Predicted ABC transporter, ATP-binding component
	KPN_01762	pucG	Serine--pyruvate aminotransferase (EC 2.6.1.51) / L-alanine:glyoxylate aminotransferase (EC 2.6.1.44)
	KPN_01761	amaB	N-carbamoyl-L-amino acid hydrolase
Position: -39 Score: 5.2 Sequence: AGCACCAGGATGGTGCA Locus tag: KPN_00886 Name: potG Funciton: Putrescine ABC transporter, ATP-binding component Locus tag: KPN_00887 Name: potH Funciton: Putrescine ABC transporter, transmembrane component 2 Locus tag: KPN_00888 Name: potI Funciton: Putrescine ABC transporter, transmembrane component 1
	KPN_00886	potG	Putrescine ABC transporter, ATP-binding component
	KPN_00887	potH	Putrescine ABC transporter, transmembrane component 2
	KPN_00888	potI	Putrescine ABC transporter, transmembrane component 1
Position: -223 Score: 4.1 Sequence: TGCACCCTGATTGCGCA Position: -189 Score: 3.8 Sequence: TGCACTGATTTTGACCA Locus tag: KPN_01038 Name: rutA Funciton: Pyrimidine oxygenase Locus tag: KPN_01037 Name: rutB Funciton: Peroxyureidoacrylate / ureidoacrylate amido hydrolase Locus tag: KPN_01036 Name: rutC Funciton: Aminoacrylate peracid reductase Locus tag: KPN_01035 Name: rutD Funciton: Aminoacrylate hydrolase Locus tag: KPN_01034 Name: rutE Funciton: 3-hydroxy propionic acid dehydrogenase Locus tag: KPN_01033 Name: rutF Funciton: Flavin reductase Locus tag: KPN_01032 Name: rutG Funciton: Uracil permease
	KPN_01038	rutA	Pyrimidine oxygenase
	KPN_01037	rutB	Peroxyureidoacrylate / ureidoacrylate amido hydrolase
	KPN_01036	rutC	Aminoacrylate peracid reductase
	KPN_01035	rutD	Aminoacrylate hydrolase
	KPN_01034	rutE	3-hydroxy propionic acid dehydrogenase
	KPN_01033	rutF	Flavin reductase
	KPN_01032	rutG	Uracil permease

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of NtrC in Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --