Regulog BirA - Desulfovibrionales

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Proteobacteria/delta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By taxonomy - Desulfovibrionales
By trascription factor - BirA
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Desulfovibrio vulgaris Hildenborough	9	2
Desulfovibrio vulgaris str. Miyazaki F	10	2
Desulfovibrio desulfuricans G20	10	2
Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774
Desulfovibrio piger ATCC 29098
Desulfovibrio salexigens DSM 2638
Desulfovibrio magneticus RS-1
Lawsonia intracellularis PHE/MN1-00
Desulfomicrobium baculatum DSM 4028
Desulfohalobium retbaense DSM 5692

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
bioB	* Desulfovibrio vulgaris Hildenborough Site: position = -230 score = 8.48477 sequence = TTGTAAACC-(15)-CGTTGACAG Gene: DVU2558: Biotin synthase (EC 2.8.1.6)	* Desulfovibrio vulgaris str. Miyazaki F Site: position = -91 score = 9.13405 sequence = TTGTAAACC-(15)-GGTTGACAA Gene: DvMF_1001: Biotin synthase (EC 2.8.1.6)	* Desulfovibrio desulfuricans G20 Site: position = -120 score = 8.70579 sequence = TTGTAAACC-(15)-AGTTGACAA Gene: Dde_2655: Biotin synthase (EC 2.8.1.6)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_1301: Biotin synthase (EC 2.8.1.6)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00325: Biotin synthase (EC 2.8.1.6)	Desulfovibrio salexigens DSM 2638 Gene: Desal_2977: Biotin synthase (EC 2.8.1.6)	Desulfovibrio magneticus RS-1 Gene: DMR_33650: Biotin synthase (EC 2.8.1.6)	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1124: Biotin synthase (EC 2.8.1.6)	Desulfohalobium retbaense DSM 5692 Gene: Dret_1048: Biotin synthase (EC 2.8.1.6)	Biotin synthase (EC 2.8.1.6)
bioA	Desulfovibrio vulgaris Hildenborough Gene: DVU2559: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1002: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio desulfuricans G20 Gene: Dde_2656: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_1300: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00326: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio salexigens DSM 2638 Gene: Desal_2978: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_2718: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfohalobium retbaense DSM 5692 Gene: Dret_1046: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
DVU2560	Desulfovibrio vulgaris Hildenborough Gene: DVU2560: conserved domain protein	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1003: conserved domain protein	Desulfovibrio desulfuricans G20 Gene: Dde_2657: conserved domain protein	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1123: conserved domain protein	Desulfohalobium retbaense DSM 5692	conserved domain protein
fabG	Desulfovibrio vulgaris Hildenborough Gene: DVU2561: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1004: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)	Desulfovibrio desulfuricans G20 Gene: Dde_2658: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02525: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1122: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)	Desulfohalobium retbaense DSM 5692	3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
acpP	Desulfovibrio vulgaris Hildenborough Gene: DVU2562: acyl carrier protein, putative	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1005: acyl carrier protein, putative	Desulfovibrio desulfuricans G20 Gene: Dde_2659: acyl carrier protein, putative	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02526: acyl carrier protein, putative	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1121: acyl carrier protein, putative	Desulfohalobium retbaense DSM 5692	acyl carrier protein, putative
fabF	Desulfovibrio vulgaris Hildenborough Gene: DVU2563: 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1006: 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)	Desulfovibrio desulfuricans G20 Gene: Dde_2660: 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02527: 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1120: 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)	Desulfohalobium retbaense DSM 5692	3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41)
Dde_2651	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1007: hypothetical thioesterase domain protein	Desulfovibrio desulfuricans G20 Gene: Dde_2661: hypothetical thioesterase domain protein	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02528: hypothetical thioesterase domain protein	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	hypothetical thioesterase domain protein
bioF	Desulfovibrio vulgaris Hildenborough Gene: DVU2564: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1008: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfovibrio desulfuricans G20 Gene: Dde_2662: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02529: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1118: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfohalobium retbaense DSM 5692	8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioD	Desulfovibrio vulgaris Hildenborough Gene: DVU2565: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1009: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfovibrio desulfuricans G20 Gene: Dde_2663: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638 Gene: Desal_2979: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1117: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfohalobium retbaense DSM 5692 Gene: Dret_1047: Dethiobiotin synthetase (EC 6.3.3.3)	Dethiobiotin synthetase (EC 6.3.3.3)

CRON 2.
birA	* Desulfovibrio vulgaris Hildenborough Site: position = -38 score = 8.48477 sequence = CTGTCAACG-(15)-GGTTTACAA Gene: DVU2557: Biotin-protein ligase (EC 6.3.4.15) / Biotin operon repressor	* Desulfovibrio vulgaris str. Miyazaki F Site: position = -38 score = 9.13405 sequence = TTGTCAACC-(15)-GGTTTACAA Gene: DvMF_1000: Biotin-protein ligase (EC 6.3.4.15) / Biotin operon repressor	* Desulfovibrio desulfuricans G20 Site: position = -21 score = 8.70579 sequence = TTGTCAACT-(15)-GGTTTACAA Gene: Dde_2654: Biotin-protein ligase (EC 6.3.4.15) / Biotin operon repressor	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Biotin-protein ligase (EC 6.3.4.15) / Biotin operon repressor

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Desulfovibrionales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --