Regulog Fur - Thermotogales

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Phylum:	Thermotogae
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By taxonomy - Thermotogales
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Thermotoga maritima MSB8	9	5
Thermotoga sp. RQ2	8	4
Thermotoga neapolitana DSM 4359	6	2
Thermotoga petrophila RKU-1	8	4
Thermotoga naphthophila RKU-10	7	3
Thermotoga lettingae TMO	2	1
Thermosipho africanus TCF52B	5	3
Thermosipho melanesiensis BI429	2	1
Fervidobacterium nodosum Rt17-B1	2	1
Petrotoga mobilis SJ95
Thermotogales bacterium TBF 19.5.1	2	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
ftr	* Thermotoga maritima MSB8 Site: position = -68 score = 4.87422 sequence = ATTGAGAATAATGATAAAC Gene: TM0417: iron permease, FTR1 family	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	* Thermosipho africanus TCF52B Site: position = -40 score = 5.61112 sequence = AATGATAATCATTCTCAAT Site: position = -46 score = 4.83333 sequence = ATTGAAAATGATAATCATT Gene: THA_366: iron permease, FTR1 family	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	iron permease, FTR1 family

CRON 2.
tdxH	* Thermotoga maritima MSB8 Site: position = -57 score = 5.6185 sequence = ATTGAGAATGGATATCAAA Gene: TM0807: peroxiredoxin	* Thermotoga sp. RQ2 Site: position = -57 score = 5.6185 sequence = ATTGAGAATGGATATCAAA Gene: TRQ2_0119: peroxiredoxin	Thermotoga neapolitana DSM 4359 Gene: CTN_1771: peroxiredoxin	* Thermotoga petrophila RKU-1 Site: position = -57 score = 5.6185 sequence = ATTGAGAATGGATATCAAA Gene: Tpet_0121: peroxiredoxin	* Thermotoga naphthophila RKU-10 Site: position = -57 score = 5.6185 sequence = ATTGAGAATGGATATCAAA Gene: Tnap_0122: peroxiredoxin	Thermotoga lettingae TMO Gene: Tlet_0977: peroxiredoxin	Thermosipho africanus TCF52B Gene: THA_1585: peroxiredoxin	Thermosipho melanesiensis BI429 Gene: Tmel_1196: peroxiredoxin	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1445: peroxiredoxin	Petrotoga mobilis SJ95 Gene: Pmob_0396: peroxiredoxin	Thermotogales bacterium TBF 19.5.1 Gene: Kole_1121: peroxiredoxin	peroxiredoxin

CRON 3.
bcp	* Thermotoga maritima MSB8 Site: position = -38 score = 5.9743 sequence = ATTGAGAATTAGTTTCAAC Gene: TM0386: bacterioferritin comigratory protein	* Thermotoga sp. RQ2 Site: position = -38 score = 5.9743 sequence = ATTGAGAATTAGTTTCAAC Gene: TRQ2_0551: bacterioferritin comigratory protein	* Thermotoga neapolitana DSM 4359 Site: position = -1 score = 5.9743 sequence = ATTGAGAATTAGTTTCAAC Gene: CTN_0311: bacterioferritin comigratory protein	* Thermotoga petrophila RKU-1 Site: position = -37 score = 5.9743 sequence = ATTGAGAATTAGTTTCAAC Gene: Tpet_0537: bacterioferritin comigratory protein	* Thermotoga naphthophila RKU-10 Site: position = -37 score = 5.9743 sequence = ATTGAGAATTAGTTTCAAC Gene: Tnap_0175: bacterioferritin comigratory protein	Thermotoga lettingae TMO Gene: Tlet_0821: bacterioferritin comigratory protein	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_0057: bacterioferritin comigratory protein	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	bacterioferritin comigratory protein

CRON 4.
feoA	* Thermotoga maritima MSB8 Site: position = -35 score = 6.41755 sequence = TTTGAGAATCATTCTCAAA Gene: TM0050: ferrous iron transport protein A	* Thermotoga sp. RQ2 Site: position = -35 score = 6.41755 sequence = TTTGAGAATCATTCTCAAA Gene: TRQ2_0896: ferrous iron transport protein A	* Thermotoga neapolitana DSM 4359 Site: position = -33 score = 6.36318 sequence = GTTGAGAATGATTCTCAAA Gene: CTN_0644: ferrous iron transport protein A	* Thermotoga petrophila RKU-1 Site: position = -35 score = 6.41755 sequence = TTTGAGAATCATTCTCAAA Gene: Tpet_0874: ferrous iron transport protein A	* Thermotoga naphthophila RKU-10 Site: position = -35 score = 6.41755 sequence = TTTGAGAATCATTCTCAAA Gene: Tnap_0680: ferrous iron transport protein A	* Thermotoga lettingae TMO Site: position = -33 score = 6.23713 sequence = ATTGAGAATGAATCTCAAT Gene: Tlet_0564: ferrous iron transport protein A	* Thermosipho africanus TCF52B Site: position = -36 score = 6.17068 sequence = GTTGAGAATTATTTTCAAT Gene: THA_39: ferrous iron transport protein A	* Thermosipho melanesiensis BI429 Site: position = -36 score = 6.10653 sequence = ATTGAGAATGAGTTTCAAT Gene: Tmel_1740: ferrous iron transport protein A	* Fervidobacterium nodosum Rt17-B1 Site: position = -106 score = 5.40999 sequence = GTTGAGAATAAGTTTCACC Gene: Fnod_0260: ferrous iron transport protein A	Petrotoga mobilis SJ95 Gene: Pmob_0965: ferrous iron transport protein A	* Thermotogales bacterium TBF 19.5.1 Site: position = -40 score = 6.43368 sequence = ATTGAGAATTATTCTCAAT Gene: Kole_0369: ferrous iron transport protein A	ferrous iron transport protein A
feoB	Thermotoga maritima MSB8 Gene: TM0051: ferrous iron transport protein B	Thermotoga sp. RQ2 Gene: TRQ2_0895: ferrous iron transport protein B	Thermotoga neapolitana DSM 4359 Gene: CTN_0643: ferrous iron transport protein B	Thermotoga petrophila RKU-1 Gene: Tpet_0873: ferrous iron transport protein B	Thermotoga naphthophila RKU-10 Gene: Tnap_0681: ferrous iron transport protein B	Thermotoga lettingae TMO Gene: Tlet_0563: ferrous iron transport protein B	Thermosipho africanus TCF52B Gene: THA_38: ferrous iron transport protein B	Thermosipho melanesiensis BI429 Gene: Tmel_1739: ferrous iron transport protein B	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_0259: ferrous iron transport protein B	Petrotoga mobilis SJ95 Gene: Pmob_0966: ferrous iron transport protein B	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0370: ferrous iron transport protein B	ferrous iron transport protein B
TM0052	Thermotoga maritima MSB8 Gene: TM0052: hypothetical protein	Thermotoga sp. RQ2 Gene: TRQ2_0894: hypothetical protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0642: hypothetical protein	Thermotoga petrophila RKU-1 Gene: Tpet_0872: hypothetical protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0682: hypothetical protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	hypothetical protein
TM0053	Thermotoga maritima MSB8 Gene: TM0053: alpha/beta hydrolase fold protein	Thermotoga sp. RQ2 Gene: TRQ2_0893: alpha/beta hydrolase fold protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0641: alpha/beta hydrolase fold protein	Thermotoga petrophila RKU-1 Gene: Tpet_0871: alpha/beta hydrolase fold protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0683: alpha/beta hydrolase fold protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	alpha/beta hydrolase fold protein
TM0054	Thermotoga maritima MSB8 Gene: TM0054: hypothetical protein	Thermotoga sp. RQ2 Gene: TRQ2_0892: hypothetical protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0640: hypothetical protein	Thermotoga petrophila RKU-1 Gene: Tpet_0870: hypothetical protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0684: hypothetical protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	hypothetical protein

CRON 5.
TM0180	* Thermotoga maritima MSB8 Site: position = -52 score = 5.41409 sequence = TTTGAGAAACAATTTCAAA Gene: TM0180: hypothetical protein	* Thermotoga sp. RQ2 Site: position = -51 score = 5.41409 sequence = TTTGAGAAACAATTTCAAA Gene: TRQ2_0768: hypothetical protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0507: hypothetical protein	* Thermotoga petrophila RKU-1 Site: position = -51 score = 5.41409 sequence = TTTGAGAAACAATTTCAAA Gene: Tpet_0744: hypothetical protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0811: hypothetical protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	hypothetical protein

CRON 6.
korA	Thermotoga maritima MSB8 Gene: TM1164: 2-ketoglutarate oxidoreductase alpha chain	Thermotoga sp. RQ2 Gene: TRQ2_1651: 2-ketoglutarate oxidoreductase alpha chain	Thermotoga neapolitana DSM 4359 Gene: CTN_1411: 2-ketoglutarate oxidoreductase alpha chain	Thermotoga petrophila RKU-1 Gene: Tpet_1585: 2-ketoglutarate oxidoreductase alpha chain	Thermotoga naphthophila RKU-10 Gene: Tnap_1605: 2-ketoglutarate oxidoreductase alpha chain	Thermotoga lettingae TMO Gene: Tlet_0570: 2-ketoglutarate oxidoreductase alpha chain	* Thermosipho africanus TCF52B Site: position = -59 score = 6.12959 sequence = TTTGAGAATTATTATCAAT Gene: THA_1977: 2-ketoglutarate oxidoreductase alpha chain	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_0055: 2-ketoglutarate oxidoreductase alpha chain	Petrotoga mobilis SJ95 Gene: Pmob_0458: 2-ketoglutarate oxidoreductase alpha chain	Thermotogales bacterium TBF 19.5.1 Gene: Kole_2137: 2-ketoglutarate oxidoreductase alpha chain	2-ketoglutarate oxidoreductase alpha chain
korB	Thermotoga maritima MSB8 Gene: TM1165: 2-ketoglutarate oxidoreductase beta chain	Thermotoga sp. RQ2 Gene: TRQ2_1650: 2-ketoglutarate oxidoreductase beta chain	Thermotoga neapolitana DSM 4359 Gene: CTN_1410: 2-ketoglutarate oxidoreductase beta chain	Thermotoga petrophila RKU-1 Gene: Tpet_1584: 2-ketoglutarate oxidoreductase beta chain	Thermotoga naphthophila RKU-10 Gene: Tnap_1604: 2-ketoglutarate oxidoreductase beta chain	Thermotoga lettingae TMO Gene: Tlet_0569: 2-ketoglutarate oxidoreductase beta chain	Thermosipho africanus TCF52B Gene: THA_1978: 2-ketoglutarate oxidoreductase beta chain	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_0056: 2-ketoglutarate oxidoreductase beta chain	Petrotoga mobilis SJ95 Gene: Pmob_0459: 2-ketoglutarate oxidoreductase beta chain	Thermotogales bacterium TBF 19.5.1 Gene: Kole_2136: 2-ketoglutarate oxidoreductase beta chain	2-ketoglutarate oxidoreductase beta chain

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Fur - Thermotogales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --