Regulog Crp - Bifidobacteriaceae
| Regulator type: | Transcription factor |
| Regulator family: | CRP |
| Regulation mode: | |
| Biological process: | Tricarboxylic acid cycle; Energy metabolism |
| Effector: | |
| Phylum: | Actinobacteria |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Bifidobacteriaceae
- By TF family - CRP
- By pathway - Tricarboxylic acid cycle
- By pathway - Energy metabolism
| Genome | Genes | Operons |
|---|---|---|
| Bifidobacterium longum subsp. infantis ATCC 15697 | 13 | 9 |
| Bifidobacterium adolescentis ATCC 15703 | 4 | 3 |
| Bifidobacterium angulatum DSM 20098 | 3 | 2 |
| Bifidobacterium animalis subsp. lactis AD011 | 5 | 3 |
| Bifidobacterium bifidum NCIMB 41171 | 8 | 7 |
| Bifidobacterium breve DSM 20213 | 13 | 9 |
| Bifidobacterium dentium Bd1 | 4 | 3 |
| Bifidobacterium gallicum DSM 20093 | 4 | 3 |
| Bifidobacterium longum NCC2705 | 12 | 8 |
| Gardnerella vaginalis 409-05 | 7 | 4 |
| Genes | Function | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||||||
| nrdH |
*
Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -209 score = 5.07558 sequence = AAATGTGAACAATGCCACATGT Gene: Blon_2480: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
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Gene: BbifN4_010100007467: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
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Bifidobacterium breve DSM 20213 Site: position = -162 score = 5.19342 sequence = AAATGTGAACAATGCCACATAT Gene: BIFBRE_00660: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
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Bifidobacterium longum NCC2705 Site: position = -162 score = 5.07558 sequence = AAATGTGAACAATGCCACATGT Gene: BL0668: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
*
Gardnerella vaginalis 409-05 Site: position = -232 score = 5.01836 sequence = TTTTGTGAAATAAATTACATTT Gene: HMPREF0424_0179: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib |
| nrdI |
Gene: Blon_2479: Ribonucleotide reduction protein NrdI |
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Gene: BLA_0312: Ribonucleotide reduction protein NrdI |
Gene: BbifN4_010100007462: Ribonucleotide reduction protein NrdI |
Gene: BIFBRE_00659: Ribonucleotide reduction protein NrdI |
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Gene: BL0669: Ribonucleotide reduction protein NrdI |
Gene: HMPREF0424_0178: Ribonucleotide reduction protein NrdI |
Ribonucleotide reduction protein NrdI |
| nrdE |
Gene: Blon_2478: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
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Gene: BLA_0311: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
Gene: BbifN4_010100007457: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
Gene: BIFBRE_00658: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
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Gene: BL0670: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
Gene: HMPREF0424_0177: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) |
| CRON 2. | |||||||||||
| pta |
Gene: Blon_1730: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BAD_0688: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BIFANG_01170: Phosphate acetyltransferase (EC 2.3.1.8) |
*
Bifidobacterium animalis subsp. lactis AD011 Site: position = -133 score = 5.20435 sequence = GAATGTGACCTGCGTCACATTC Gene: BLA_1484: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BbifN4_010100003454: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BIFBRE_01069: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BDP_1007: Phosphate acetyltransferase (EC 2.3.1.8) |
*
Bifidobacterium gallicum DSM 20093 Site: position = -283 score = 5.87403 sequence = GATTGTGACACAGGTCACGTTC Gene: BIFGAL_01466: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: BL0968: Phosphate acetyltransferase (EC 2.3.1.8) |
Gene: HMPREF0424_0624: Phosphate acetyltransferase (EC 2.3.1.8) |
Phosphate acetyltransferase (EC 2.3.1.8) |
| ackA |
Gene: Blon_1731: Acetate kinase (EC 2.7.2.1) |
Gene: BAD_0689: Acetate kinase (EC 2.7.2.1) |
Gene: BIFANG_01171: Acetate kinase (EC 2.7.2.1) |
Gene: BLA_1485: Acetate kinase (EC 2.7.2.1) |
Gene: BbifN4_010100003449: Acetate kinase (EC 2.7.2.1) |
Gene: BIFBRE_01068: Acetate kinase (EC 2.7.2.1) |
Gene: BDP_1008: Acetate kinase (EC 2.7.2.1) |
Gene: BIFGAL_01465: Acetate kinase (EC 2.7.2.1) |
Gene: BL0969: Acetate kinase (EC 2.7.2.1) |
Gene: HMPREF0424_0623: Acetate kinase (EC 2.7.2.1) |
Acetate kinase (EC 2.7.2.1) |
| CRON 3. | |||||||||||
| Blon_0037 |
*
Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -290 score = 4.74576 sequence = CGATGTGAGAAAGCTCACGGTC Gene: Blon_0037: Major facilitator superfamily, general substrate transporter |
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*
Bifidobacterium bifidum NCIMB 41171 Site: position = -242 score = 4.67478 sequence = CGATGTGAATAAGTTCACGGAT Gene: BbifN4_010100009176: Major facilitator superfamily, general substrate transporter |
*
Bifidobacterium breve DSM 20213 Site: position = -208 score = 4.61846 sequence = AACCGTGACGATACTCACATGA Gene: BIFBRE_01254: Major facilitator superfamily, general substrate transporter |
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Bifidobacterium longum NCC2705 Site: position = -290 score = 4.442 sequence = CGATGTGAGAAAGCTCATAGCT Gene: BL0613: Major facilitator superfamily, general substrate transporter |
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Major facilitator superfamily, general substrate transporter |
| CRON 4. | |||||||||||
| nox |
*
Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -105 score = 4.8426 sequence = TAACGTGATCTTCCTCACATTT Gene: Blon_2322: Uncharacterized NAD(FAD)-dependent dehydrogenase |
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Gene: BLA_0232: Uncharacterized NAD(FAD)-dependent dehydrogenase |
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Bifidobacterium bifidum NCIMB 41171 Site: position = -131 score = 4.43363 sequence = CATCGTGATGTTCGTCACATCC Gene: BbifN4_010100008701: Uncharacterized NAD(FAD)-dependent dehydrogenase |
*
Bifidobacterium breve DSM 20213 Site: position = -66 score = 4.7275 sequence = AAACGTGACCTTCCTCACAGCT Gene: BIFBRE_00121: Uncharacterized NAD(FAD)-dependent dehydrogenase |
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Gene: BIFGAL_00071: Uncharacterized NAD(FAD)-dependent dehydrogenase |
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Bifidobacterium longum NCC2705 Site: position = -105 score = 4.8426 sequence = TAACGTGATCTTCCTCACATTT Gene: BL1266: Uncharacterized NAD(FAD)-dependent dehydrogenase |
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Uncharacterized NAD(FAD)-dependent dehydrogenase |
| CRON 5. | |||||||||||
| aldB |
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Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -78 score = 4.91021 sequence = TATAGTGGTATAGCTCACGTTG Gene: Blon_2239: Alpha-acetolactate decarboxylase (EC 4.1.1.5) |
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Bifidobacterium bifidum NCIMB 41171 Site: position = 5 score = 4.91802 sequence = GTTCGTGAGGCAGGTCACAGCG Gene: BbifN4_010100007742: Alpha-acetolactate decarboxylase (EC 4.1.1.5) |
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Bifidobacterium breve DSM 20213 Site: position = -76 score = 4.28835 sequence = ACACGTGTCATAAATCACGCAC Site: position = -38 score = 4.66983 sequence = GATTGTGACGTACAGCACTGGG Gene: BIFBRE_00271: Alpha-acetolactate decarboxylase (EC 4.1.1.5) |
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Alpha-acetolactate decarboxylase (EC 4.1.1.5) |
| CRON 6. | |||||||||||
| ilvC2 |
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Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -170 score = 4.6843 sequence = TGGCGTGAAATAGCTCACGTTG Gene: Blon_0136: Ketol-acid reductoisomerase (EC 1.1.1.86) |
2
Bifidobacterium adolescentis ATCC 15703 Gene: BAD_0082: Ketol-acid reductoisomerase (EC 1.1.1.86) Gene: BAD_0081: Ketol-acid reductoisomerase (EC 1.1.1.86) |
Gene: BIFANG_00307: Ketol-acid reductoisomerase (EC 1.1.1.86) |
Gene: BLA_0138: Ketol-acid reductoisomerase (EC 1.1.1.86) |
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Bifidobacterium bifidum NCIMB 41171 Site: position = -218 score = 4.69487 sequence = AATAGTGAGATGGTTCACGTTG Gene: BbifN4_010100000325: Ketol-acid reductoisomerase (EC 1.1.1.86) |
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Bifidobacterium breve DSM 20213 Site: position = -171 score = 5.47619 sequence = AATAGTGACCTAGCTCACGTTG Gene: BIFBRE_01899: Ketol-acid reductoisomerase (EC 1.1.1.86) |
2
Bifidobacterium dentium Bd1 Gene: BDP_0118: Ketol-acid reductoisomerase (EC 1.1.1.86) Gene: BDP_0119: Ketol-acid reductoisomerase (EC 1.1.1.86) |
Gene: BIFGAL_02007: Ketol-acid reductoisomerase (EC 1.1.1.86) |
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Bifidobacterium longum NCC2705 Site: position = -163 score = 5.47619 sequence = AATAGTGACCTAGCTCACGTTG Gene: BL0530: Ketol-acid reductoisomerase (EC 1.1.1.86) |
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Ketol-acid reductoisomerase (EC 1.1.1.86) |
| CRON 7. | |||||||||||
| ispD |
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Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -50 score = 4.84292 sequence = AGATGTGATGCAGTTCACGGAC Gene: Blon_0353: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
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Gene: BLA_0317: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
Gene: BbifN4_010100007497: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
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Bifidobacterium breve DSM 20213 Site: position = -50 score = 4.76362 sequence = AGCTGTGAGGCAGGTCACGAAC Gene: BIFBRE_00201: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
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Gene: BIFGAL_00734: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
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Bifidobacterium longum NCC2705 Site: position = -50 score = 4.84292 sequence = AGATGTGATGCAGTTCACGGAC Gene: BL0324: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
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2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) |
| pcp |
Gene: Blon_0354: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
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Gene: BLA_0318: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
Gene: BbifN4_010100007502: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
Gene: BIFBRE_00202: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
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Gene: BIFGAL_00735: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
Gene: BL0323: Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
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Pyrrolidone-carboxylate peptidase (EC 3.4.19.3) |
| CRON 8. | |||||||||||
| ldh |
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Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -183 score = 5.52814 sequence = TAACGTGATAAACATCACAGTT Gene: Blon_0840: L-lactate dehydrogenase (EC 1.1.1.27) |
*
Bifidobacterium adolescentis ATCC 15703 Site: position = -4 score = 5.43909 sequence = AGCTGTGACGAAAATCACTTTT Gene: BAD_1117: L-lactate dehydrogenase (EC 1.1.1.27) |
Gene: BIFANG_00987: L-lactate dehydrogenase (EC 1.1.1.27) |
Gene: BLA_0792: L-lactate dehydrogenase (EC 1.1.1.27) |
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Bifidobacterium bifidum NCIMB 41171 Site: position = -145 score = 5.78575 sequence = CAATGTGACGCAAATCACCTTG Gene: BbifN4_010100002254: L-lactate dehydrogenase (EC 1.1.1.27) |
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Bifidobacterium breve DSM 20213 Site: position = -183 score = 5.80495 sequence = TAACGTGACGAAAATCACATAA Gene: BIFBRE_01807: L-lactate dehydrogenase (EC 1.1.1.27) |
*
Bifidobacterium dentium Bd1 Site: position = -143 score = 5.49723 sequence = AAGTGTGGCGCAAATCACGTTT Gene: BDP_1558: L-lactate dehydrogenase (EC 1.1.1.27) |
Gene: BIFGAL_00305: L-lactate dehydrogenase (EC 1.1.1.27) |
*
Bifidobacterium longum NCC2705 Site: position = -183 score = 5.36499 sequence = TAACGTGATAAACATCACAGTA Gene: BL1308: L-lactate dehydrogenase (EC 1.1.1.27) |
Gene: HMPREF0424_0584: L-lactate dehydrogenase (EC 1.1.1.27) |
L-lactate dehydrogenase (EC 1.1.1.27) |
| CRON 9. | |||||||||||
| pflB |
*
Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -81 score = 5.0646 sequence = CAATGTGAGATAGCTCACCCCC Gene: Blon_1715: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium adolescentis ATCC 15703 Site: position = -126 score = 5.59541 sequence = GATTGTGATTTATGTCACTAAT Gene: BAD_0992: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium angulatum DSM 20098 Site: position = -114 score = 5.86304 sequence = AAATGTGAGATAGCTCACTTCG Gene: BIFANG_01531: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium animalis subsp. lactis AD011 Site: position = -123 score = 5.68162 sequence = AAATGTGACCAAGCTCACGCGT Gene: BLA_0967: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium bifidum NCIMB 41171 Site: position = -108 score = 5.36758 sequence = GAATGTGAGATAAGTCACGCCG Gene: BbifN4_010100005855: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium breve DSM 20213 Site: position = -113 score = 5.27563 sequence = GAATGTGAGATAGCTCACTCCC Gene: BIFBRE_01106: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium dentium Bd1 Site: position = -126 score = 5.69287 sequence = ATATGTGAAATAAATCACTTTT Gene: BDP_1376: Pyruvate formate-lyase (EC 2.3.1.54) |
*
Bifidobacterium gallicum DSM 20093 Site: position = -116 score = 5.84852 sequence = AAATGTGACCAAGGTCACGCTG Gene: BIFGAL_01295: Pyruvate formate-lyase (EC 2.3.1.54) |
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Bifidobacterium longum NCC2705 Site: position = -75 score = 5.21301 sequence = CAATGTGAGATAGCTCACTCCC Gene: BL0951: Pyruvate formate-lyase (EC 2.3.1.54) |
*
Gardnerella vaginalis 409-05 Site: position = -119 score = 5.26928 sequence = AAATGTGATATATTTCACTAGA Gene: HMPREF0424_0886: Pyruvate formate-lyase (EC 2.3.1.54) |
Pyruvate formate-lyase (EC 2.3.1.54) |
| pflA |
Gene: Blon_1714: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BAD_0991: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BIFANG_01530: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BLA_0968: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BbifN4_010100005850: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BIFBRE_01107: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BDP_1375: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BIFGAL_01294: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: BL0950: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Gene: HMPREF0424_0885: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) |
| CRON 10. | |||||||||||
| adh |
*
Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -149 score = 6.41413 sequence = TATTGTGACTCAGGTCACATAT Gene: Blon_2241: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium adolescentis ATCC 15703 Site: position = -109 score = 5.3126 sequence = AAGTGTGTCCTAGGTCACAAAA Gene: BAD_0319: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium angulatum DSM 20098 Site: position = -129 score = 5.05822 sequence = TATTGTGGGGCAGGTCACAGGC Gene: BIFANG_00716: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium animalis subsp. lactis AD011 Site: position = -76 score = 5.81023 sequence = GATTGTGAGACAACTCACATCT Gene: BLA_0358: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium bifidum NCIMB 41171 Site: position = -110 score = 4.85238 sequence = GATTGTGGCGTAGGCCACAGAT Gene: BbifN4_010100007737: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium breve DSM 20213 Site: position = -126 score = 5.62001 sequence = TATTGTGATGCAGGTCACAGGC Gene: BIFBRE_00269: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium dentium Bd1 Site: position = -109 score = 5.92021 sequence = GATTGTGACTCAGGTCACAACG Gene: BDP_0426: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium gallicum DSM 20093 Site: position = -94 score = 5.29386 sequence = ATTAGTGAATCAGGTCACATTG Gene: BIFGAL_00796: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Bifidobacterium longum NCC2705 Site: position = -149 score = 5.93812 sequence = TATTGTGCCTCAGGTCACATAT Gene: BL1575: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Gardnerella vaginalis 409-05 Site: position = -96 score = 5.77594 sequence = AATTGTGACTTGTATCACATAT Gene: HMPREF0424_0254: Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) |
| CRON 11. | |||||||||||
| gnd |
2
Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0666: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) Gene: Blon_0207: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BAD_0628: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BIFANG_01254: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BLA_1007: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BbifN4_010100008062: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BIFBRE_02011: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BDP_0847: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BIFGAL_01249: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Gene: BL0444: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
*
Gardnerella vaginalis 409-05 Site: position = -215 score = 4.81886 sequence = AAATGTAATTTATTTCACAAAA Gene: HMPREF0424_0180: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |