Regulog Fur - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 106 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	50	20
Staphylococcus capitis SK14	32	15
Staphylococcus epidermidis ATCC 12228	20	10
Staphylococcus carnosus subsp. carnosus TM300	28	14
Staphylococcus haemolyticus JCSC1435	28	14
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	25	15
Macrococcus caseolyticus JCSC5402	14	7

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
yfmC	* Staphylococcus aureus subsp. aureus N315 Site: position = -59 score = 6.34452 sequence = AATGATAATTGTTATCAAT Gene: SA1979: iron(III) dicitrate ABC transporter binding protein	* Staphylococcus capitis SK14 Site: position = -60 score = 6.06315 sequence = AATGAGAATCGTTATCAAT Gene: STACA0001_1300: iron(III) dicitrate ABC transporter binding protein	* Staphylococcus epidermidis ATCC 12228 Site: position = -52 score = 6.13485 sequence = ATTGAGAATCGTTATCAAT Gene: SE1768: iron(III) dicitrate ABC transporter binding protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -192 score = 6.06315 sequence = AATGAGAATCGTTATCAAT Gene: Sca_1680: iron(III) dicitrate ABC transporter binding protein	* Staphylococcus haemolyticus JCSC1435 Site: position = -62 score = 6.57031 sequence = ATTGATAATCGTTATCAAT Gene: SH0863: iron(III) dicitrate ABC transporter binding protein	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -61 score = 5.99319 sequence = ACCGATAATCATTATCAAT Gene: SSP0709: iron(III) dicitrate ABC transporter binding protein	Macrococcus caseolyticus JCSC5402	iron(III) dicitrate ABC transporter binding protein
yfmD	Staphylococcus aureus subsp. aureus N315 Gene: SA1978: iron(III) dicitrate ABC transporter permease component	Staphylococcus capitis SK14 Gene: STACA0001_1301: iron(III) dicitrate ABC transporter permease component	Staphylococcus epidermidis ATCC 12228 Gene: SE1767: iron(III) dicitrate ABC transporter permease component	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1679: iron(III) dicitrate ABC transporter permease component	Staphylococcus haemolyticus JCSC1435 Gene: SH0864: iron(III) dicitrate ABC transporter permease component	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0710: iron(III) dicitrate ABC transporter permease component	Macrococcus caseolyticus JCSC5402	iron(III) dicitrate ABC transporter permease component
yfmE	Staphylococcus aureus subsp. aureus N315 Gene: SA1977: iron(III) dicitrate ABC transporter permease component	Staphylococcus capitis SK14 Gene: STACA0001_1302: iron(III) dicitrate ABC transporter permease component	Staphylococcus epidermidis ATCC 12228 Gene: SE1766: iron(III) dicitrate ABC transporter permease component	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1678: iron(III) dicitrate ABC transporter permease component	Staphylococcus haemolyticus JCSC1435 Gene: SH0865: iron(III) dicitrate ABC transporter permease component	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0711: iron(III) dicitrate ABC transporter permease component	Macrococcus caseolyticus JCSC5402	iron(III) dicitrate ABC transporter permease component

CRON 2.
trxB	* Staphylococcus aureus subsp. aureus N315 Site: position = -110 score = 6.61601 sequence = AATGATAATAATTATCAAT Gene: SA2162: ferredoxin--NADP reductase	* Staphylococcus capitis SK14 Site: position = -62 score = 6.32118 sequence = AATGATAATAATTATCACT Gene: STACA0001_1105: ferredoxin--NADP reductase	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -58 score = 5.27489 sequence = GTTGAGAATAATTTTCAAT Gene: Sca_1872: ferredoxin--NADP reductase	* Staphylococcus haemolyticus JCSC1435 Site: position = -51 score = 6.54432 sequence = AATGATAATAATTATCATT Gene: SH0681: ferredoxin--NADP reductase	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -68 score = 6.57031 sequence = ATTGATAATCGTTATCAAT Gene: SSP0530: ferredoxin--NADP reductase	* Macrococcus caseolyticus JCSC5402 Site: position = -79 score = 6.84181 sequence = ATTGATAATGATTATCAAT Gene: MCCL_0165: ferredoxin--NADP reductase	ferredoxin--NADP reductase

CRON 3.
tatA	* Staphylococcus aureus subsp. aureus N315 Site: position = -67 score = 6.28965 sequence = ATTGATAATCATTATCGTT Gene: SA0335: putative sec-independant protein translocase	* Staphylococcus capitis SK14 Site: position = -71 score = 6.25493 sequence = ATTGATAATCTTTATCAAT Gene: STACA0001_1113: putative sec-independant protein translocase	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -63 score = 6.18324 sequence = ATTGATAATCTTTATCATT Gene: Sca_2211a: putative sec-independent protein translocase	* Staphylococcus haemolyticus JCSC1435 Site: position = -70 score = 6.10084 sequence = ATTGATAATATTTATCAAT Gene: SH0688: putative sec-independant protein translocase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	putative sec-independant protein translocase
tatC	Staphylococcus aureus subsp. aureus N315 Gene: SA0334: putative sec-independant protein translocase	Staphylococcus capitis SK14 Gene: STACA0001_1112: putative sec-independant protein translocase	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2212: putative sec-independant protein translocase	Staphylococcus haemolyticus JCSC1435 Gene: SH0687: putative sec-independant protein translocase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1720: putative sec-independant protein translocase	putative sec-independant protein translocase

CRON 4.
sstD2	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -51 score = 6.45913 sequence = ATTGAAAATGATTATCAAT Gene: SH1529: putative siderophore ABC transporter	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -59 score = 6.45913 sequence = ATTGATAATGATTTTCAAT Gene: SSP1368: putative siderophore ABC transporter	Macrococcus caseolyticus JCSC5402	putative siderophore ABC transporter

CRON 5.
sstA	* Staphylococcus aureus subsp. aureus N315 Site: position = -43 score = 6.69842 sequence = AATGATAATGATTATCATT Gene: SA0688: putative siderophore ABC transporter permease	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -78 score = 6.69842 sequence = AATGATAATCATTATCATT Gene: SE0515: putative siderophore ABC transporter permease	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -78 score = 6.17882 sequence = AGTGATAATGATTATCAGT Gene: Sca_0381: putative siderophore ABC transporter permease	* Staphylococcus haemolyticus JCSC1435 Site: position = -68 score = 6.21796 sequence = AATGATAATCATTATCGTT Gene: SH2160: putative siderophore ABC transporter permease	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -75 score = 6.40645 sequence = ATTGATAATGATTATCATA Gene: SSP1984: putative siderophore ABC transporter permease	* Macrococcus caseolyticus JCSC5402 Site: position = -33 score = 6.41621 sequence = ATTGATAACTATTATCAAT Gene: MCCL_1838: putative siderophore ABC transporter permease	putative siderophore ABC transporter permease
sstB	Staphylococcus aureus subsp. aureus N315 Gene: SA0689: putative siderophore ABC transporter permease	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0516: putative siderophore ABC transporter permease	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0382: putative siderophore ABC transporter permease	Staphylococcus haemolyticus JCSC1435 Gene: SH2159: putative siderophore ABC transporter permease	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1983: putative siderophore ABC transporter permease	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1837: putative siderophore ABC transporter permease	putative siderophore ABC transporter permease
sstC	Staphylococcus aureus subsp. aureus N315 Gene: SA0690: putative siderophore ABC transporter ATP-binding protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0517: putative siderophore ABC transporter ATP-binding protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0383: putative siderophore ABC transporter ATP-binding protein	Staphylococcus haemolyticus JCSC1435 Gene: SH2158: putative siderophore ABC transporter ATP-binding protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1982: putative siderophore ABC transporter ATP-binding protein	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1836: putative siderophore ABC transporter ATP-binding protein	putative siderophore ABC transporter ATP-binding protein
sstD	Staphylococcus aureus subsp. aureus N315 Gene: SA0691: putative siderophore ABC transporter	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0518: putative siderophore ABC transporter	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0384: homolog of lipoprotein SstD	Staphylococcus haemolyticus JCSC1435 Gene: SH2157: putative siderophore ABC transporter	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1981: putative siderophore ABC transporter	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1835: putative siderophore ABC transporter	putative siderophore ABC transporter
SH2156	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -48 score = 6.27547 sequence = ATTGATAATCGTTATCACT Gene: SH2156: hypothetical protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
sstD3	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435 Gene: SH2155: putative siderophore ABC transporter	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	putative siderophore ABC transporter

CRON 6.
sirA	* Staphylococcus aureus subsp. aureus N315 Site: position = -50 score = 5.51846 sequence = CGTGATAATGATTCTCATT Site: position = -181 score = 6.11151 sequence = ATTGATAATGATTCTCACT Gene: SA0111: siderophore staphylobactin ABC transporter, substrate-binding protein SirA	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	siderophore staphylobactin ABC transporter, substrate-binding protein SirA
sirB	Staphylococcus aureus subsp. aureus N315 Gene: SA0110: siderophore staphylobactin ABC transporter, permease protein SirB	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	siderophore staphylobactin ABC transporter, permease protein SirB
sirC	Staphylococcus aureus subsp. aureus N315 Gene: SA0109: siderophore staphylobactin ABC transporter, permease protein SirC	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	siderophore staphylobactin ABC transporter, permease protein SirC

CRON 7.
sbnA	* Staphylococcus aureus subsp. aureus N315 Site: position = -68 score = 6.11151 sequence = AGTGAGAATCATTATCAAT Site: position = -199 score = 5.51846 sequence = AATGAGAATCATTATCACG Gene: SA0112: Siderophore staphylobactin biosynthesis protein SbnA	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnA
sbnB	Staphylococcus aureus subsp. aureus N315 Gene: SA0113: Siderophore staphylobactin biosynthesis protein SbnB	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnB
sbnC	Staphylococcus aureus subsp. aureus N315 Gene: SA0114: Siderophore staphylobactin biosynthesis protein SbnC	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnC
sbnD	Staphylococcus aureus subsp. aureus N315 Gene: SA0115: Siderophore staphylobactin biosynthesis protein SbnD	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnD
sbnE	Staphylococcus aureus subsp. aureus N315 Gene: SA0116: Siderophore staphylobactin biosynthesis protein SbnE	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnE
sbnF	Staphylococcus aureus subsp. aureus N315 Gene: SA0117: Siderophore staphylobactin biosynthesis protein SbnF	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnF
sbnG	Staphylococcus aureus subsp. aureus N315 Gene: SA0118: Siderophore staphylobactin biosynthesis protein SbnG	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnG
sbnH	Staphylococcus aureus subsp. aureus N315 Gene: SA0119: Siderophore staphylobactin biosynthesis protein SbnH	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnH
sbnI	Staphylococcus aureus subsp. aureus N315 Gene: SA0120: Siderophore staphylobactin biosynthesis protein SbnI	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Siderophore staphylobactin biosynthesis protein SbnI

CRON 8.
SA1982	* Staphylococcus aureus subsp. aureus N315 Site: position = -45 score = 5.85029 sequence = AATGATAATGATTCTTATT Gene: SA1982: putative permease of the major facilitator superfamily	* Staphylococcus capitis SK14 Site: position = -41 score = 6.61601 sequence = AATGATAATTATTATCAAT Gene: STACA0001_1297: putative permease of the major facilitator superfamily	* Staphylococcus epidermidis ATCC 12228 Site: position = -40 score = 6.61601 sequence = AATGATAATTATTATCAAT Gene: SE1771: putative permease of the major facilitator superfamily	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -42 score = 6.77011 sequence = AATGATAATCATTATCAAT Gene: Sca_1683: putative permease of the major facilitator superfamily	* Staphylococcus haemolyticus JCSC1435 Site: position = -54 score = 6.35744 sequence = AATGATATTCATTATCAAT Gene: SH0860: putative permease of the major facilitator superfamily	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -38 score = 6.61601 sequence = AATGATAATTATTATCAAT Gene: SSP0706: putative permease of the major facilitator superfamily	Macrococcus caseolyticus JCSC5402	putative permease of the major facilitator superfamily
iucC	Staphylococcus aureus subsp. aureus N315 Gene: SA1981: putative aerobactin biosynthesis protein, IucA/IucC family	Staphylococcus capitis SK14 Gene: STACA0001_1298: putative aerobactin biosynthesis protein, IucA/IucC family	Staphylococcus epidermidis ATCC 12228 Gene: SE1770: putative aerobactin biosynthesis protein, IucA/IucC family	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1682: putative aerobactin biosynthesis protein, IucA/IucC family	Staphylococcus haemolyticus JCSC1435 Gene: SH0861: putative aerobactin biosynthesis protein, IucA/IucC family	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0707: putative aerobactin biosynthesis protein, IucA/IucC family	Macrococcus caseolyticus JCSC5402	putative aerobactin biosynthesis protein, IucA/IucC family
SA1980	Staphylococcus aureus subsp. aureus N315 Gene: SA1980: putative amino acid racemase	Staphylococcus capitis SK14 Gene: STACA0001_1299: putative amino acid racemase	Staphylococcus epidermidis ATCC 12228 Gene: SE1769: putative amino acid racemase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1681: putative amino acid racemase	Staphylococcus haemolyticus JCSC1435 Gene: SH0862: putative amino acid racemase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0708: putative amino acid racemase	Macrococcus caseolyticus JCSC5402	putative amino acid racemase

CRON 9.
SA0757	* Staphylococcus aureus subsp. aureus N315 Site: position = -41 score = 5.59368 sequence = ATTGAGAAGTATTATCATT Gene: SA0757: putative NAD(P)H nitroreductase	* Staphylococcus capitis SK14 Site: position = -42 score = 5.82153 sequence = ATTGATAATTGTTATCAAC Gene: STACA0001_0225: putative NAD(P)H nitroreductase	* Staphylococcus epidermidis ATCC 12228 Site: position = -44 score = 5.97726 sequence = ATTGATAATGGTTATCATG Gene: SE0593: putative NAD(P)H nitroreductase	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -39 score = 6.69842 sequence = AATGATAATGATTATCATT Gene: Sca_0449: putative NAD(P)H nitroreductase	Staphylococcus haemolyticus JCSC1435 Gene: SH2054: putative NAD(P)H nitroreductase	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -38 score = 5.96184 sequence = ATTGAAAATAGTTATCATT Gene: SSP1872: putative NAD(P)H nitroreductase	* Macrococcus caseolyticus JCSC5402 Site: position = -41 score = 6.41621 sequence = ATTGATAATAGTTATCAAT Gene: MCCL_0533: putative NAD(P)H nitroreductase	putative NAD(P)H nitroreductase

CRON 10.
iucB	* Staphylococcus aureus subsp. aureus N315 Site: position = -75 score = 5.85029 sequence = AATAAGAATCATTATCATT Gene: SA1983: putative aerobactin biosynthesis protein, IucA/IucC family	* Staphylococcus capitis SK14 Site: position = -82 score = 6.61601 sequence = ATTGATAATAATTATCATT Gene: STACA0001_1296: putative aerobactin biosynthesis protein, IucA/IucC family	* Staphylococcus epidermidis ATCC 12228 Site: position = -81 score = 6.61601 sequence = ATTGATAATAATTATCATT Gene: SE1772: putative aerobactin biosynthesis protein, IucA/IucC family	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -83 score = 6.77011 sequence = ATTGATAATGATTATCATT Gene: Sca_1684: putative aerobactin biosynthesis protein, IucA/IucC family	* Staphylococcus haemolyticus JCSC1435 Site: position = -79 score = 6.35744 sequence = ATTGATAATGAATATCATT Gene: SH0859: putative aerobactin biosynthesis protein, IucA/IucC family	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -83 score = 6.61601 sequence = ATTGATAATAATTATCATT Gene: SSP0705: putative aerobactin biosynthesis protein, IucA/IucC family	Macrococcus caseolyticus JCSC5402	putative aerobactin biosynthesis protein, IucA/IucC family

CRON 11.
isdH	* Staphylococcus aureus subsp. aureus N315 Site: position = -50 score = 6.68771 sequence = ATTGATAATTATTATCAAT Gene: SA1552: cell surface receptor IsdH for hemoglobin-haptoglobin complexes	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	cell surface receptor IsdH for hemoglobin-haptoglobin complexes

CRON 12.
isdB	* Staphylococcus aureus subsp. aureus N315 Site: position = -52 score = 6.47365 sequence = ATTGATAATGATTATCAGT Gene: SA0976: cell surface receptor IsdB for hemoglobin-haptoglobin complexes	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	cell surface receptor IsdB for hemoglobin-haptoglobin complexes

CRON 13.
isdC	* Staphylococcus aureus subsp. aureus N315 Site: position = -69 score = 6.28575 sequence = AATGATAATCATTATTATT Site: position = -148 score = 6.57031 sequence = ATTGATAATGGTTATCAAT Gene: SA0978: iron-regulated surface determinant protein C (Staphylococcaliron-regulated protein D)	* Staphylococcus capitis SK14 Site: position = -86 score = 5.36716 sequence = GTTGATAACTATTTTCATT Gene: STACA0001_2141: iron-regulated surface determinant protein C (Staphylococcaliron-regulated protein D)	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	iron-regulated surface determinant protein C (Staphylococcaliron-regulated protein D)
isdA	* Staphylococcus aureus subsp. aureus N315 Site: position = -79 score = 6.57031 sequence = ATTGATAACCATTATCAAT Site: position = -158 score = 6.28575 sequence = AATAATAATGATTATCATT Gene: SA0977: iron Transport-associated domain family	2 Staphylococcus capitis SK14* Site: position = -46 score = 5.68817 sequence = ATTGATAAATAATATCAAT Gene: STACA0001_2139: iron-regulated surface determinant protein A (Staphylococcaltransferrin-binding protein A) (Fur-regulated protein A) Gene: STACA0001_2142: iron Transport-associated domain family	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	iron Transport-associated domain family
isdE	Staphylococcus aureus subsp. aureus N315 Gene: SA0980: periplasmic binding protein	Staphylococcus capitis SK14 Gene: STACA0001_2143: periplasmic binding protein	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	periplasmic binding protein
isdF	Staphylococcus aureus subsp. aureus N315 Gene: SA0981: iron/heme permease	Staphylococcus capitis SK14 Gene: STACA0001_2144: iron/heme permease	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	iron/heme permease
STACA0001_2145	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14 Gene: STACA0001_2145: iron(III) dicitrate transport ATP-binding protein FecE	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	iron(III) dicitrate transport ATP-binding protein FecE
srtB	Staphylococcus aureus subsp. aureus N315 Gene: SA0982: sortase, SrtB family	Staphylococcus capitis SK14 Gene: STACA0001_2146: sortase, SrtB family	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	sortase, SrtB family
isdG	Staphylococcus aureus subsp. aureus N315 Gene: SA0983: heme-degrading monooxygenase IsdG (Iron-regulatedsurface determinant isdG) (Iron-responsive surface determinant isdG)(Heme oxygenase)	Staphylococcus capitis SK14 Gene: STACA0001_2147: heme-degrading monooxygenase IsdG (Iron-regulatedsurface determinant isdG) (Iron-responsive surface determinant isdG)(Heme oxygenase)	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -144 score = 6.18055 sequence = ATTGAGAATAATTATCATT Gene: Sca_0030: heme-degrading monooxygenase IsdG (Iron-regulatedsurface determinant isdG) (Iron-responsive surface determinant isdG)(Heme oxygenase)	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	heme-degrading monooxygenase IsdG (Iron-regulatedsurface determinant isdG) (Iron-responsive surface determinant isdG)(Heme oxygenase)
isdD	Staphylococcus aureus subsp. aureus N315 Gene: SA0979: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein

CRON 14.
ftnA	* Staphylococcus aureus subsp. aureus N315 Site: position = -94 score = 5.53249 sequence = AATTATAATTATTATTATT Site: position = -167 score = 5.76788 sequence = AATGATATTTATTCTCAAT Site: position = -198 score = 5.6638 sequence = AATTATAATCATTCTCATT Gene: SA1709: ferritin	* Staphylococcus capitis SK14 Site: position = -111 score = 5.16624 sequence = AATGAGAATGGTTATCTCT Gene: STACA0001_1946: ferritin	* Staphylococcus epidermidis ATCC 12228 Site: position = -128 score = 5.16872 sequence = AATTAGAATAATTATTAAT Gene: SE1578: ferritin	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -101 score = 4.93781 sequence = GATTATAATAATTATTATT Gene: SH1060: ferritin	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0898: ferritin	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1624: ferritin	ferritin

CRON 15.
fhuD2	* Staphylococcus aureus subsp. aureus N315 Site: position = -30 score = 6.45913 sequence = ATTGATAATCATTTTCAAT Gene: SA2079: ferric hydroxamate binding protein of ABC transporter	* Staphylococcus capitis SK14 Site: position = -31 score = 6.27547 sequence = ATTGATAATCGTTATCACT Gene: STACA0001_1209: ferric hydroxamate binding protein of ABC transporter	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -36 score = 6.11593 sequence = AATGATAATCGTTTTCAAT Gene: Sca_1778: ferric hydroxamate binding protein of ABC transporter	* Staphylococcus haemolyticus JCSC1435 Site: position = -30 score = 5.59295 sequence = ATTGATAATCGTTTTCAAC Gene: SH0768: ferric hydroxamate binding protein of ABC transporter	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -30 score = 6.09097 sequence = ACTGATAATCATTTTCAAT Gene: SSP0623: ferric hydroxamate binding protein of ABC transporter	* Macrococcus caseolyticus JCSC5402 Site: position = -32 score = 6.35744 sequence = AATGATAATCAATATCAAT Gene: MCCL_0133: ferric hydroxamate binding protein of ABC transporter	ferric hydroxamate binding protein of ABC transporter
fhuD5	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -93 score = 5.70717 sequence = ATTGATAATCGTTTTCGAT Gene: SSP0422: ferric hydroxamate binding protein of ABC transporter	Macrococcus caseolyticus JCSC5402	ferric hydroxamate binding protein of ABC transporter
fhuD4	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -68 score = 6.57031 sequence = ATTGATAACGATTATCAAT Gene: SSP0529: ferric hydroxamate binding protein of ABC transporter	Macrococcus caseolyticus JCSC5402	ferric hydroxamate binding protein of ABC transporter
fhuD3	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -69 score = 6.42914 sequence = ATTGATAATCAATATCAAT Gene: SSP1382: ferric hydroxamate binding protein of ABC transporter	Macrococcus caseolyticus JCSC5402	ferric hydroxamate binding protein of ABC transporter

CRON 16.
fhuA	* Staphylococcus aureus subsp. aureus N315 Site: position = -102 score = 6.24876 sequence = CATGATAATCATTATCAAT Gene: SA0602: ferrichrome transport ATP-binding protein FhuA	* Staphylococcus capitis SK14 Site: position = -109 score = 6.40645 sequence = TATGATAATGATTATCAAT Gene: STACA0001_0381: ferrichrome transport ATP-binding protein FhuA	* Staphylococcus epidermidis ATCC 12228 Site: position = -119 score = 6.18331 sequence = TGTGATAATGATTATCAAT Gene: SE0421: ferrichrome transport ATP-binding protein FhuA	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -222 score = 6.40645 sequence = TATGATAATGATTATCAAT Gene: Sca_0295: ferrichrome transport ATP-binding protein FhuA	* Staphylococcus haemolyticus JCSC1435 Site: position = -69 score = 6.25235 sequence = TATGATAATTATTATCAAT Gene: SH2247: ferrichrome transport ATP-binding protein FhuA	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -111 score = 6.33475 sequence = TATGATAATGATTATCATT Gene: SSP2073: ferrichrome transport ATP-binding protein FhuA	* Macrococcus caseolyticus JCSC5402 Site: position = -46 score = 6.84181 sequence = ATTGATAATCATTATCAAT Gene: MCCL_0166: ferrichrome transport ATP-binding protein FhuA	ferrichrome transport ATP-binding protein FhuA
fhuB	Staphylococcus aureus subsp. aureus N315 Gene: SA0603: ferrichrome transport permease FhuB	Staphylococcus capitis SK14 Gene: STACA0001_0380: ferrichrome transport permease FhuB	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0296: ferrichrome transport permease	Staphylococcus haemolyticus JCSC1435 Gene: SH2246: ferrichrome transport permease FhuB	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2072: ferrichrome transport permease FhuB	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0167: ferrichrome transport permease FhuB	ferrichrome transport permease FhuB
fhuG	Staphylococcus aureus subsp. aureus N315 Gene: SA0604: ferrichrome transport permease FhuG	Staphylococcus capitis SK14 Gene: STACA0001_0379: ferrichrome transport permease FhuG	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0297: ferrichrome transport permease FhuG	Staphylococcus haemolyticus JCSC1435 Gene: SH2245: ferrichrome transport permease FhuG	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2071: ferrichrome transport permease FhuG	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0168: ferrichrome transport permease FhuG	ferrichrome transport permease FhuG

CRON 17.
feoA	* Staphylococcus aureus subsp. aureus N315 Site: position = -41 score = 6.06261 sequence = AGTGATAATGATTATTATT Gene: SA2338: putative ferrous iron transport protein A	* Staphylococcus capitis SK14 Site: position = -42 score = 6.42914 sequence = ATTGATAATGATTATTAAT Gene: STACA0001_0945: putative ferrous iron transport protein A	* Staphylococcus epidermidis ATCC 12228 Site: position = -36 score = 6.35744 sequence = AATGATAATGATTATTAAT Gene: SE2115: putative ferrous iron transport protein A	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -51 score = 6.15752 sequence = ATTGATAATAATAATCAAT Gene: Sca_2028: putative ferrous iron transport protein A	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -36 score = 6.35744 sequence = ATTGATAATGATTATTATT Gene: SSP2435: putative ferrous iron transport protein A	Macrococcus caseolyticus JCSC5402	putative ferrous iron transport protein A
feoB	Staphylococcus aureus subsp. aureus N315 Gene: SA2337: ferrous iron transport protein B	Staphylococcus capitis SK14 Gene: STACA0001_0946: ferrous iron transport protein B	Staphylococcus epidermidis ATCC 12228 Gene: SE2114: ferrous iron transport protein B	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2029: putative ferrous iron transport protein B	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -268 score = 6.30503 sequence = ATTGAAAATAATTATCAAT Gene: MCCL_1625: ferrous iron transport protein B	ferrous iron transport protein B

CRON 18.
efeO	* Staphylococcus aureus subsp. aureus N315 Site: position = -157 score = 5.72937 sequence = TTTGATAATTATTATCAAC Gene: SA0331: Ferrous iron transport periplasmic protein EfeO	* Staphylococcus capitis SK14 Site: position = -93 score = 6.84181 sequence = ATTGATAATGATTATCAAT Gene: STACA0001_1108: Ferrous iron transport periplasmic protein EfeO	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -69 score = 6.57031 sequence = ATTGATAACGATTATCAAT Gene: Sca_2215: Ferrous iron transport periplasmic protein EfeO	* Staphylococcus haemolyticus JCSC1435 Site: position = -158 score = 6.47814 sequence = TTTGATAATGATTATCAAT Gene: SH0684: Ferrous iron transport periplasmic protein EfeO	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Ferrous iron transport periplasmic protein EfeO
efeB	Staphylococcus aureus subsp. aureus N315 Gene: SA0332: Ferrous iron transport peroxidase EfeB	Staphylococcus capitis SK14 Gene: STACA0001_1109: Ferrous iron transport peroxidase EfeB	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2214: Ferrous iron transport peroxidase EfeB	Staphylococcus haemolyticus JCSC1435 Gene: SH0685: Ferrous iron transport peroxidase EfeB	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Ferrous iron transport peroxidase EfeB
efeU	Staphylococcus aureus subsp. aureus N315 Gene: SA0333: Ferrous iron transport permease EfeU	Staphylococcus capitis SK14 Gene: STACA0001_1110: Ferrous iron transport permease EfeU	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2213: Ferrous iron transport permease EfeU	Staphylococcus haemolyticus JCSC1435 Gene: SH0686: Ferrous iron transport permease EfeU	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Ferrous iron transport permease EfeU

CRON 19.
citB	* Staphylococcus aureus subsp. aureus N315 Site: position = -198 score = 6.25225 sequence = ATTGATAATTATTCTCAAT Gene: SA1184: aconitate hydratase	* Staphylococcus capitis SK14 Site: position = -198 score = 6.13485 sequence = ATTGATAACCATTCTCAAT Gene: STACA0001_1597: aconitate hydratase	* Staphylococcus epidermidis ATCC 12228 Site: position = -198 score = 6.13485 sequence = ATTGATAACCATTCTCAAT Gene: SE1032: aconitate hydratase	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -190 score = 5.59807 sequence = ATTGAAAACAATTCTCAAT Gene: Sca_0991: aconitate hydratase	* Staphylococcus haemolyticus JCSC1435 Site: position = -202 score = 5.95197 sequence = AATGAAAATCATTCTCAAT Gene: SH1558: aconitate hydratase	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -193 score = 4.84884 sequence = GCTGATAATGATTCTCAAC Gene: SSP1408: aconitate hydratase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1008: aconitate hydratase	aconitate hydratase

CRON 20.
MCCL_1067	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -185 score = 5.88028 sequence = AATGAAAATGATTCTCATT Gene: MCCL_1067: hypothetical protein	hypothetical protein
arlR	2 Staphylococcus aureus subsp. aureus N315* Gene: SA1247: response regulator ArlR Site: position = -586 score = 5.51836 sequence = AgTGAgAATCATTgTCAAT Site: position = -619 score = 5.86445 sequence = ATTGATAATCATTtTCAAc Gene: SA1248: response regulator ArlR	* Staphylococcus capitis SK14 Site: position = -256 score = 5.8132 sequence = ATTGAGAATCATTGTCAAT Site: position = -289 score = 5.25952 sequence = ATTGATAATCATTTACAAC Gene: STACA0001_1664: response regulator ArlR	Staphylococcus epidermidis ATCC 12228 Gene: SE1100: response regulator ArlR	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -152 score = 6.24866 sequence = ATTGATAATGATTGTCAAT Site: position = -185 score = 5.93777 sequence = ATTGATAATCATTTTCAAG Gene: Sca_1060: response regulator ArlR	* Staphylococcus haemolyticus JCSC1435 Site: position = -212 score = 6.24866 sequence = ATTGATAATCATTGTCAAT Site: position = -245 score = 6.09546 sequence = ATTGATAATCATTTTCAAA Gene: SH1490: response regulator ArlR	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -207 score = 6.45913 sequence = ATTGATAATCATTTTCAAT Gene: SSP1323: response regulator ArlR	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1066: response regulator ArlR	response regulator ArlR
arlS	Staphylococcus aureus subsp. aureus N315 Gene: SA1246: signal transduction histidine kinase ArlS	Staphylococcus capitis SK14 Gene: STACA0001_1663: signal transduction histidine kinase ArlS	Staphylococcus epidermidis ATCC 12228 Gene: SE1099: signal transduction histidine kinase ArlS	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1059: signal transduction histidine kinase ArlS	Staphylococcus haemolyticus JCSC1435 Gene: SH1491: signal transduction histidine kinase ArlS	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1324: signal transduction histidine kinase ArlS	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1065: signal transduction histidine kinase ArlS	signal transduction histidine kinase ArlS
SE1101	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = 61 score = 6.24866 sequence = ATTGATAATGATTgTCAAT Site: position = 28 score = 6.45913 sequence = ATTGATAATCATTtTCAAT Gene: SE1101: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Fur - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --