Regulog Zur - Frankineae/Propionibacterineae/Pseudonocardiaceae

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Zinc homeostasis
Effector:	Zinc ion, (Zn2+)
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 24 sites [see more]

Member of regulog collections

By taxonomy - Frankineae/Propionibacterineae/Pseudonocardiaceae
By trascription factor - Zur
By TF family - FUR
By effector - Zinc ion, (Zn2+)
By pathway - Zinc homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Actinosynnema mirum DSM 43827	18	7
Saccharopolyspora erythraea NRRL 2338	10	3
Saccharomonospora viridis DSM 43017	3	1
Nakamurella multipartita DSM 44233	5	3
Frankia sp. EAN1pec	5	2
Frankia sp. CcI3
Acidothermus cellulolyticus 11B
Propionibacterium acnes KPA171202	13	4
Nocardioides sp. JS614	4	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
rpmB2	* Actinosynnema mirum DSM 43827 Site: position = -39 score = 5.25293 sequence = GGTGAAAATGATTGTCATT Gene: Amir_0607: LSU ribosomal protein L28p	* Saccharopolyspora erythraea NRRL 2338 Site: position = -34 score = 5.64265 sequence = AATGAAAACGGATGTCGTT Site: position = -88 score = 4.8512 sequence = GTCGGCAACGGTTTTCATT Gene: SACE_0754: LSU ribosomal protein L28p	Saccharomonospora viridis DSM 43017	* Nakamurella multipartita DSM 44233 Site: position = -126 score = 4.91838 sequence = AACGAGACCGATTCTCAGT Gene: Namu_3856: LSU ribosomal protein L28p	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	* Propionibacterium acnes KPA171202 Site: position = -43 score = 5.13255 sequence = TATGATAATGATTCTCATA Gene: PPA2158: LSU ribosomal protein L28p	Nocardioides sp. JS614	LSU ribosomal protein L28p
rpmG2	Actinosynnema mirum DSM 43827 Gene: Amir_0606: LSU ribosomal protein L33p	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0753: LSU ribosomal protein L33p	Saccharomonospora viridis DSM 43017	* Nakamurella multipartita DSM 44233 Site: position = -43 score = 4.91643 sequence = ACTGAGAATCGGTCTCGTT Gene: Namu_3855: LSU ribosomal protein L33p	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA2160: LSU ribosomal protein L33p	Nocardioides sp. JS614	LSU ribosomal protein L33p
rpsN2	Actinosynnema mirum DSM 43827 Gene: Amir_0605: SSU ribosomal protein S14p	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0752: SSU ribosomal protein S14p	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA2161: SSU ribosomal protein S14p	Nocardioides sp. JS614	SSU ribosomal protein S14p
rpsR2	Actinosynnema mirum DSM 43827 Gene: Amir_0604: SSU ribosomal protein S18p	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0751: SSU ribosomal protein S18p	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	SSU ribosomal protein S18p
rpmF2	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA2162: LSU ribosomal protein L32p	Nocardioides sp. JS614	LSU ribosomal protein L32p

CRON 2.
znuA2	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233 Gene: Namu_1071: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Frankia sp. EAN1pec Site: position = -25 score = 5.83885 sequence = ATCGACAACCGTTTTCATT Gene: Franean1_7253: Zinc ABC transporter, periplasmic-binding protein ZnuA	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Zinc ABC transporter, periplasmic-binding protein ZnuA
Franean1_7254	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec Gene: Franean1_7254: ABC-type uncharacterized transport system, duplicated ATPase component	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	ABC-type uncharacterized transport system, duplicated ATPase component
Franean1_7255	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec Gene: Franean1_7255: ABC-type Mn2+/Zn2+ transport systems, permease components	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	ABC-type Mn2+/Zn2+ transport systems, permease components
Franean1_7256	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec Gene: Franean1_7256: ABC-type Mn2+/Zn2+ transport systems, permease components	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	ABC-type Mn2+/Zn2+ transport systems, permease components
Namu_1072	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	* Nakamurella multipartita DSM 44233 Site: position = -27 score = 5.48021 sequence = AACGAGAACCGTTCTCAGT Gene: Namu_1072: Quinoprotein amine dehydrogenase, beta chain-like	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Quinoprotein amine dehydrogenase, beta chain-like
Namu_1070	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233 Gene: Namu_1070: Quinoprotein amine dehydrogenase, beta chain-like	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Quinoprotein amine dehydrogenase, beta chain-like

CRON 3.
TIGR03773	* Actinosynnema mirum DSM 43827 Site: position = -60 score = 5.50103 sequence = ATTGAAAATGATTGTCCTT Gene: Amir_4776: Conserved hypothetical protein CHP03773, ABC transporter-like	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	* Propionibacterium acnes KPA171202 Site: position = -48 score = 5.73345 sequence = ATCGATAACCGTTCTCATT Gene: PPA1500: Conserved hypothetical protein CHP03773, ABC transporter-like	Nocardioides sp. JS614	Conserved hypothetical protein CHP03773, ABC transporter-like
znuA3	* Actinosynnema mirum DSM 43827 Site: position = -78 score = 5.90179 sequence = ATTGAAAACGGTTGTCGTT Gene: Amir_4768: Zinc ABC transporter, periplasmic-binding protein ZnuA	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA1501: Zinc ABC transporter, periplasmic-binding protein ZnuA	Nocardioides sp. JS614	Zinc ABC transporter, periplasmic-binding protein ZnuA
PPA1502	Actinosynnema mirum DSM 43827	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA1502: Surface-anchored repeat, actinobacteria	Nocardioides sp. JS614	Surface-anchored repeat, actinobacteria
znuC3	Actinosynnema mirum DSM 43827 Gene: Amir_4770: Zinc ABC transporter, ATP-binding protein ZnuC	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA1503: Zinc ABC transporter, ATP-binding protein ZnuC	Nocardioides sp. JS614	Zinc ABC transporter, ATP-binding protein ZnuC
znuB3	Actinosynnema mirum DSM 43827 Gene: Amir_4771: Zinc ABC transporter, inner membrane permease protein ZnuB	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202 Gene: PPA1504: Zinc ABC transporter, inner membrane permease protein ZnuB	Nocardioides sp. JS614	Zinc ABC transporter, inner membrane permease protein ZnuB
Amir_4769	Actinosynnema mirum DSM 43827 Gene: Amir_4769: hypothetical protein	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	hypothetical protein

CRON 4.
Amir_3101	* Actinosynnema mirum DSM 43827 Site: position = -65 score = 5.71153 sequence = GTTGAAAACCGTTGTCATT Gene: Amir_3101: Surface-anchored repeat, actinobacteria	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Surface-anchored repeat, actinobacteria
Amir_3100	Actinosynnema mirum DSM 43827 Gene: Amir_3100: Surface-anchored repeat, actinobacteria	Saccharopolyspora erythraea NRRL 2338	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Surface-anchored repeat, actinobacteria

CRON 5.
znuA	* Actinosynnema mirum DSM 43827 Site: position = -49 score = 5.19824 sequence = CTCGACAACGGTTACCATT Gene: Amir_0352: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Saccharopolyspora erythraea NRRL 2338 Site: position = -68 score = 5.24099 sequence = CATGACAACGGTTTCCGTT Gene: SACE_0453: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Saccharomonospora viridis DSM 43017 Site: position = -89 score = 5.20491 sequence = ATCGAAAATCATTTCCAAT Gene: Svir_35300: Zinc ABC transporter, periplasmic-binding protein ZnuA	Nakamurella multipartita DSM 44233 Gene: Namu_4923: Zinc ABC transporter, periplasmic-binding protein ZnuA	Frankia sp. EAN1pec	Frankia sp. CcI3 Gene: Francci3_2479: Zinc ABC transporter, periplasmic-binding protein ZnuA	Acidothermus cellulolyticus 11B Gene: Acel_2086: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Propionibacterium acnes KPA171202 Site: position = -45 score = 5.13725 sequence = TACGACAATGGTTATCACT Gene: PPA0617: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Nocardioides sp. JS614 Site: position = -29 score = 5.31096 sequence = TTTGACAATCATTCTCAAT Site: position = -7 score = 4.45756 sequence = GCTGAGAATGATTCTCATG Gene: Noca_1937: Zinc ABC transporter, periplasmic-binding protein ZnuA	Zinc ABC transporter, periplasmic-binding protein ZnuA
znuC	Actinosynnema mirum DSM 43827 Gene: Amir_0353: Zinc ABC transporter, ATP-binding protein ZnuC	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0452: Zinc ABC transporter, ATP-binding protein ZnuC	Saccharomonospora viridis DSM 43017 Gene: Svir_35290: Zinc ABC transporter, ATP-binding protein ZnuC	Nakamurella multipartita DSM 44233 Gene: Namu_4922: Zinc ABC transporter, ATP-binding protein ZnuC	Frankia sp. EAN1pec	Frankia sp. CcI3 Gene: Francci3_2478: Zinc ABC transporter, ATP-binding protein ZnuC	Acidothermus cellulolyticus 11B Gene: Acel_2087: Zinc ABC transporter, ATP-binding protein ZnuC	Propionibacterium acnes KPA171202 Gene: PPA0616: Zinc ABC transporter, ATP-binding protein ZnuC	Nocardioides sp. JS614 Gene: Noca_1936: Zinc ABC transporter, ATP-binding protein ZnuC	Zinc ABC transporter, ATP-binding protein ZnuC
znuB	Actinosynnema mirum DSM 43827 Gene: Amir_0354: Zinc ABC transporter, inner membrane permease protein ZnuB	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0451: Zinc ABC transporter, inner membrane permease protein ZnuB	Saccharomonospora viridis DSM 43017 Gene: Svir_35280: Zinc ABC transporter, inner membrane permease protein ZnuB	Nakamurella multipartita DSM 44233 Gene: Namu_4921: Zinc ABC transporter, inner membrane permease protein ZnuB	Frankia sp. EAN1pec	2 Frankia sp. CcI3 Gene: Francci3_2477: Zinc ABC transporter, inner membrane permease protein ZnuB Gene: Francci3_2476: Zinc ABC transporter, inner membrane permease protein ZnuB	2 Acidothermus cellulolyticus 11B Gene: Acel_2088: Zinc ABC transporter, inner membrane permease protein ZnuB Gene: Acel_2089: Zinc ABC transporter, inner membrane permease protein ZnuB	Propionibacterium acnes KPA171202 Gene: PPA0615: Zinc ABC transporter, inner membrane permease protein ZnuB	Nocardioides sp. JS614 Gene: Noca_1935: Zinc ABC transporter, inner membrane permease protein ZnuB	Zinc ABC transporter, inner membrane permease protein ZnuB
zur	2 Actinosynnema mirum DSM 43827* Gene: Amir_1261: Zinc homeostasis transcriptional regulator Zur, Fur family Site: position = -55 score = 5.54674 sequence = ATTGAAAACGATTGTCTTT Gene: Amir_4413: Zinc homeostasis transcriptional regulator Zur, Fur family	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_1498: Zinc homeostasis transcriptional regulator Zur, Fur family	Saccharomonospora viridis DSM 43017 Gene: Svir_13670: Zinc homeostasis transcriptional regulator Zur, Fur family	Nakamurella multipartita DSM 44233 Gene: Namu_0066: Zinc homeostasis transcriptional regulator Zur, Fur family	* Frankia sp. EAN1pec Site: position = -134 score = 5.12123 sequence = AATGAAAACCGATGTCAAC Gene: Franean1_7263: Zinc homeostasis transcriptional regulator Zur, Fur family	Frankia sp. CcI3 Gene: Francci3_0061: Zinc homeostasis transcriptional regulator Zur, Fur family	Acidothermus cellulolyticus 11B Gene: Acel_2085: Zinc homeostasis transcriptional regulator Zur, Fur family	Propionibacterium acnes KPA171202 Gene: PPA0948: Zinc homeostasis transcriptional regulator Zur, Fur family	Nocardioides sp. JS614 Gene: Noca_1934: Zinc homeostasis transcriptional regulator Zur, Fur family	Zinc homeostasis transcriptional regulator Zur, Fur family

CRON 6.
yciC	* Actinosynnema mirum DSM 43827 Site: position = -52 score = 5.53543 sequence = AATGACAATCGTTTCCGTT Gene: Amir_4416: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	* Saccharopolyspora erythraea NRRL 2338 Site: position = -65 score = 5.41889 sequence = AACGACATCCGTTTTCATT Site: position = -11 score = 5.04579 sequence = AATGAAAACCGTTGCCGAC Gene: SACE_0755: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family
rpmE2	Actinosynnema mirum DSM 43827 Gene: Amir_4415: LSU ribosomal protein L31p	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0756: LSU ribosomal protein L31p	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	* Propionibacterium acnes KPA171202 Site: position = -72 score = 5.12638 sequence = TATGAGAATCATTATCATA Gene: PPA2157: LSU ribosomal protein L31p	Nocardioides sp. JS614	LSU ribosomal protein L31p
rpmF2	Actinosynnema mirum DSM 43827 Gene: Amir_4414: LSU ribosomal protein L32p	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_0757: LSU ribosomal protein L32p	Saccharomonospora viridis DSM 43017	Nakamurella multipartita DSM 44233	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Propionibacterium acnes KPA171202	Nocardioides sp. JS614	LSU ribosomal protein L32p

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Zur - Frankineae/Propionibacterineae/Pseudonocardiaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --