Regulog HcpR - Desulfuromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	CRP
Regulation mode:	activator
Biological process:	Nitrosative stress response
Effector:	Nitric oxide
Phylum:	Proteobacteria/delta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 44 sites [see more]

Member of regulog collections

By taxonomy - Desulfuromonadales
By trascription factor - HcpR
By TF family - CRP
By effector - Nitric oxide
By pathway - Nitrosative stress response

Statistics of regulated genes
Genome	Genes	Operons
Desulfuromonas acetoxidans DSM 684	1	1
Geobacter lovleyi SZ	7	5
Geobacter metallireducens GS-15	10	7
Geobacter sp. FRC-32	7	4
Geobacter sp. M21	9	6
Geobacter sulfurreducens PCA	12	7
Geobacter uraniumreducens Rf4	10	7
Pelobacter carbinolicus str. DSM 2380	1	1
Pelobacter propionicus DSM 2379	6	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
SSF140683	Desulfuromonas acetoxidans DSM 684	2 Geobacter lovleyi SZ* Site: position = -120 score = 4.54334 sequence = GCATGACGTATGTCAATT Site: position = -74 score = 4.6116 sequence = TATTGATTCAGATCAAAC Gene: Glov_0219: SP0561-like superfamily hypothetical protein Site: position = -187 score = 4.6751 sequence = GCATGACTGCGGTCAAAA Gene: Glov_2648: SP0561-like superfamily hypothetical protein	* Geobacter metallireducens GS-15 Site: position = -73 score = 4.63141 sequence = TTTTGATTCACATCATAA Gene: Gmet_2513: SP0561-like superfamily hypothetical protein	* Geobacter sp. FRC-32 Site: position = -73 score = 5.4493 sequence = TTTTGACCCAGGTCATAA Gene: Geob_0943: SP0561-like superfamily hypothetical protein	* Geobacter sp. M21 Site: position = -76 score = 5.13754 sequence = TTTTGACCCATGTCATAA Gene: GM21_1234: SP0561-like superfamily hypothetical protein	* Geobacter sulfurreducens PCA Site: position = -77 score = 5.04445 sequence = TCTTGACCCACATCATAA Gene: GSU2659: SP0561-like superfamily hypothetical protein	* Geobacter uraniumreducens Rf4 Site: position = -72 score = 5.28284 sequence = TTTTGACCCACGTCATAA Gene: Gura_0769: SP0561-like superfamily hypothetical protein	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	SP0561-like superfamily hypothetical protein
frdX2	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ Gene: Glov_2649: Ferredoxin fused to uncharacterized domain	Geobacter metallireducens GS-15	Geobacter sp. FRC-32 Gene: Geob_0944: Ferredoxin fused to uncharacterized domain	Geobacter sp. M21 Gene: GM21_1233: Ferredoxin fused to uncharacterized domain	Geobacter sulfurreducens PCA Gene: GSU2660: Ferredoxin fused to uncharacterized domain	Geobacter uraniumreducens Rf4 Gene: Gura_0770: Ferredoxin fused to uncharacterized domain	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	Ferredoxin fused to uncharacterized domain
COG3945	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ Gene: Glov_2650: Hemerythrin HHE cation binding domain hypothetical protein	Geobacter metallireducens GS-15 Gene: Gmet_2516: Hemerythrin HHE cation binding domain hypothetical protein	Geobacter sp. FRC-32 Gene: Geob_0945: Hemerythrin HHE cation binding domain hypothetical protein	Geobacter sp. M21 Gene: GM21_1232: Hemerythrin HHE cation binding domain hypothetical protein	Geobacter sulfurreducens PCA Gene: GSU2661: Hemerythrin HHE cation binding domain hypothetical protein	Geobacter uraniumreducens Rf4 Gene: Gura_0771: Hemerythrin HHE cation binding domain hypothetical protein	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	Hemerythrin HHE cation binding domain hypothetical protein

CRON 2.
dnrN	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ Gene: Glov_0199: Nitric oxide-dependent regulator DnrN or NorA	Geobacter metallireducens GS-15 Gene: Gmet_3494: Nitric oxide-dependent regulator DnrN or NorA	Geobacter sp. FRC-32 Gene: Geob_2234: Nitric oxide-dependent regulator DnrN or NorA	* Geobacter sp. M21 Site: position = -123 score = 5.21975 sequence = TCTTGACCTGGATCATGA Gene: GM21_3032: Nitric oxide-dependent regulator DnrN or NorA	Geobacter sulfurreducens PCA Gene: GSU0849: Nitric oxide-dependent regulator DnrN or NorA	* Geobacter uraniumreducens Rf4 Site: position = -269 score = 5.28631 sequence = ATTTGACCTACATCAAGG Gene: Gura_0432: Nitric oxide-dependent regulator DnrN or NorA	Pelobacter carbinolicus str. DSM 2380	2 Pelobacter propionicus DSM 2379* Gene: Ppro_3700: Nitric oxide-dependent regulator DnrN or NorA Site: position = -132 score = 5.3593 sequence = CCATGACCTGGGTCAAAT Gene: Ppro_1206: Nitric oxide-dependent regulator DnrN or NorA	Nitric oxide-dependent regulator DnrN or NorA

CRON 3.
ndh	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ Gene: Glov_0215: NADH dehydrogenase (EC 1.6.99.3)	* Geobacter metallireducens GS-15 Site: position = -81 score = 5.2932 sequence = TTTTGACCACGGTCAAGG Gene: Gmet_3041: NADH dehydrogenase (EC 1.6.99.3)	Geobacter sp. FRC-32	Geobacter sp. M21	* Geobacter sulfurreducens PCA Site: position = -75 score = 5.15781 sequence = GCTTGACCTGTGTCAAGG Gene: GSU0493: NADH dehydrogenase (EC 1.6.99.3)	Geobacter uraniumreducens Rf4	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	NADH dehydrogenase (EC 1.6.99.3)
COG2006	Desulfuromonas acetoxidans DSM 684	* Geobacter lovleyi SZ Site: position = -288 score = 4.55439 sequence = TCATGACCGGCATCATGA Gene: Glov_3209: Iron-sulfur cluster-binding protein	Geobacter metallireducens GS-15 Gene: Gmet_3040: Iron-sulfur cluster-binding protein	Geobacter sp. FRC-32 Gene: Geob_0754: Iron-sulfur cluster-binding protein	Geobacter sp. M21 Gene: GM21_0488: Iron-sulfur cluster-binding protein	Geobacter sulfurreducens PCA Gene: GSU0494: Iron-sulfur cluster-binding protein	2 Geobacter uraniumreducens Rf4 Gene: Gura_4011: Iron-sulfur cluster-binding protein Gene: Gura_2519: Iron-sulfur cluster-binding protein	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0620: Iron-sulfur cluster-binding protein	Pelobacter propionicus DSM 2379 Gene: Ppro_3096: Iron-sulfur cluster-binding protein	Iron-sulfur cluster-binding protein

CRON 4.
nrfH	Desulfuromonas acetoxidans DSM 684 Gene: Dace_0514: Cytochrome c nitrite reductase, small subunit NrfH	Geobacter lovleyi SZ Gene: Glov_1043: Cytochrome c nitrite reductase, small subunit NrfH	* Geobacter metallireducens GS-15 Site: position = -112 score = 5.27321 sequence = CTTTGACATAAGTCAAGG Gene: Gmet_0295: Cytochrome c nitrite reductase, small subunit NrfH	Geobacter sp. FRC-32	Geobacter sp. M21	* Geobacter sulfurreducens PCA Site: position = -165 score = 4.69908 sequence = TGTTGACTTGAGTCAAAC Gene: GSU3155: Cytochrome c nitrite reductase, small subunit NrfH	Geobacter uraniumreducens Rf4 Gene: Gura_0664: Cytochrome c nitrite reductase, small subunit NrfH	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_2867: Cytochrome c nitrite reductase, small subunit NrfH	2 Pelobacter propionicus DSM 2379* Site: position = -212 score = 5.00784 sequence = AATTGATCTAGATCAAAA Gene: Ppro_3707: Cytochrome c nitrite reductase, small subunit NrfH Site: position = -241 score = 4.8399 sequence = AATTGATTTTGGTCAAGG Gene: Ppro_1199: Cytochrome c nitrite reductase, small subunit NrfH	Cytochrome c nitrite reductase, small subunit NrfH
nrfA	Desulfuromonas acetoxidans DSM 684 Gene: Dace_0513: Cytochrome c552 precursor (EC 1.7.2.2)	Geobacter lovleyi SZ Gene: Glov_1042: Cytochrome c552 precursor (EC 1.7.2.2)	2 Geobacter metallireducens GS-15* Gene: Gmet_0294: Cytochrome c552 precursor (EC 1.7.2.2) Site: position = -196 score = 5.27321 sequence = CCTTGACTTATGTCAAAG Gene: Gmet_0296: Cytochrome c552 precursor (EC 1.7.2.2)	Geobacter sp. FRC-32	Geobacter sp. M21	Geobacter sulfurreducens PCA Gene: GSU3154: Cytochrome c552 precursor (EC 1.7.2.2)	Geobacter uraniumreducens Rf4 Gene: Gura_0665: Cytochrome c552 precursor (EC 1.7.2.2)	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_2866: Cytochrome c552 precursor (EC 1.7.2.2)	Pelobacter propionicus DSM 2379 Gene: Ppro_1200: Cytochrome c552 precursor (EC 1.7.2.2)	Cytochrome c552 precursor (EC 1.7.2.2)

CRON 5.
ygbA	Desulfuromonas acetoxidans DSM 684 Gene: Dace_0508: hypothetical protein involved in nitrosative stress	* Geobacter lovleyi SZ Site: position = -51 score = 4.52031 sequence = TTTTGACCGTTGTCATGC Gene: Glov_3448: hypothetical protein involved in nitrosative stress	* Geobacter metallireducens GS-15 Site: position = -2 score = 4.98817 sequence = TTTTGACATTGGTCATGA Gene: Gmet_3184: hypothetical protein involved in nitrosative stress	* Geobacter sp. FRC-32 Site: position = -39 score = 4.68158 sequence = ATTTGACTTTTGTCATAT Gene: Geob_1234: hypothetical protein involved in nitrosative stress	* Geobacter sp. M21 Site: position = -39 score = 5.1518 sequence = TCTTGACTTTGGTCATGA Gene: GM21_0136: hypothetical protein involved in nitrosative stress	* Geobacter sulfurreducens PCA Site: position = -51 score = 5.29168 sequence = TTTTGACCTGCGTCATGA Gene: GSU3248: hypothetical protein involved in nitrosative stress	* Geobacter uraniumreducens Rf4 Site: position = -50 score = 4.76081 sequence = TTTTGACTTTTGTCATGT Gene: Gura_0293: hypothetical protein involved in nitrosative stress	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0573: hypothetical protein involved in nitrosative stress	* Pelobacter propionicus DSM 2379 Site: position = -39 score = 5.17044 sequence = TATTGACCTGGGTCATGT Gene: Ppro_0306: hypothetical protein involved in nitrosative stress	hypothetical protein involved in nitrosative stress
frdX1	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ	Geobacter metallireducens GS-15 Gene: Gmet_3185: Ferredoxin fused to uncharacterized domain	Geobacter sp. FRC-32 Gene: Geob_1235: Ferredoxin fused to uncharacterized domain	Geobacter sp. M21 Gene: GM21_0137: Ferredoxin fused to uncharacterized domain	Geobacter sulfurreducens PCA Gene: GSU3247: Ferredoxin fused to uncharacterized domain	Geobacter uraniumreducens Rf4 Gene: Gura_0294: Ferredoxin fused to uncharacterized domain	* Pelobacter carbinolicus str. DSM 2380 Site: position = -91 score = 4.74428 sequence = TCTTGACAGGAATCAAGG Gene: Pcar_1702: Ferredoxin fused to uncharacterized domain	Pelobacter propionicus DSM 2379 Gene: Ppro_0307: Ferredoxin fused to uncharacterized domain	Ferredoxin fused to uncharacterized domain

CRON 6.
PF02085	Desulfuromonas acetoxidans DSM 684	Geobacter lovleyi SZ	Geobacter metallireducens GS-15	Geobacter sp. FRC-32	* Geobacter sp. M21 Site: position = -117 score = 5.35522 sequence = CCTTGACTTTGGTCAAGG Gene: GM21_4043: cytochrome c family protein, putative	* Geobacter sulfurreducens PCA Site: position = -39 score = 5.20886 sequence = CTTTGACTTACGTCAAAC Gene: GSU0105: cytochrome c family protein, putative	* Geobacter uraniumreducens Rf4 Site: position = -75 score = 5.14746 sequence = ATTTGACTTTAGTCAAGG Gene: Gura_4255: cytochrome c family protein, putative	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	cytochrome c family protein, putative

CRON 7.
COG1917	Desulfuromonas acetoxidans DSM 684	* Geobacter lovleyi SZ Site: position = -83 score = 4.90174 sequence = GTTTGACCTGTATCAAGG Gene: Glov_2960: hypothetical protein	* Geobacter metallireducens GS-15 Site: position = -24 score = 5.24174 sequence = TTTTGACCGGGGTCAAAC Gene: Gmet_0691: hypothetical protein	* Geobacter sp. FRC-32 Site: position = -87 score = 5.01705 sequence = TCTTGACCTGCATCAATT Gene: Geob_1248: hypothetical protein	* Geobacter sp. M21 Site: position = -83 score = 4.40467 sequence = GATTGACTTGCATCAATT Gene: GM21_0411: hypothetical protein	* Geobacter sulfurreducens PCA Site: position = -295 score = 5.2567 sequence = CCTTGACCTGCATCAAGG Site: position = -78 score = 4.88222 sequence = CCTTGACTCCCGTCAATG Gene: GSU0224: hypothetical protein	* Geobacter uraniumreducens Rf4 Site: position = -277 score = 5.23584 sequence = CCTTGACCTGCGTCAATT Gene: Gura_0346: hypothetical protein	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379 Gene: Ppro_2801: hypothetical protein	hypothetical protein

CRON 8.
hcp	* Desulfuromonas acetoxidans DSM 684 Site: position = -86 score = 5.15359 sequence = TCTTGATCTGGATCAAAT Gene: Dace_0679: Hydroxylamine reductase (EC 1.7.-.-)	Geobacter lovleyi SZ	* Geobacter metallireducens GS-15 Site: position = -150 score = 5.5318 sequence = TCTTGACCAAGGTCAAAG Gene: Gmet_2834: Hydroxylamine reductase (EC 1.7.-.-)	* Geobacter sp. FRC-32 Site: position = -150 score = 4.83692 sequence = TATTGACTTTTGTCAAAG Gene: Geob_1617: Hydroxylamine reductase (EC 1.7.-.-)	2 Geobacter sp. M21* Gene: GM21_3038: Hydroxylamine reductase (EC 1.7.-.-) Site: position = -117 score = 5.35311 sequence = TTATGACTTAGGTCAAGG Gene: GM21_3228: Hydroxylamine reductase (EC 1.7.-.-)	* Geobacter sulfurreducens PCA Site: position = -143 score = 5.50393 sequence = CCTTGACCCACGTCAAGG Gene: GSU0674: Hydroxylamine reductase (EC 1.7.-.-)	2 Geobacter uraniumreducens Rf4* Site: position = -269 score = 5.4614 sequence = ACTTGACCAAGGTCAAAG Gene: Gura_1364: Hydroxylamine reductase (EC 1.7.-.-) Site: position = -223 score = 4.91029 sequence = TATTGACTTTGATCAAGG Gene: Gura_0663: Hydroxylamine reductase (EC 1.7.-.-)	Pelobacter carbinolicus str. DSM 2380	Pelobacter propionicus DSM 2379	Hydroxylamine reductase (EC 1.7.-.-)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HcpR - Desulfuromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --