Regulog MetJ - Pasteurellales
| Regulator type: | Transcription factor |
| Regulator family: | MetJ |
| Regulation mode: | repressor |
| Biological process: | Methionine metabolism; Methionine biosynthesis |
| Effector: | S-adenosylmethionine |
| Phylum: | Proteobacteria/Gamma |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Pasteurellales
- By trascription factor - MetJ
- By TF family - MetJ
- By effector - S-adenosylmethionine
- By pathway - Methionine metabolism
- By pathway - Methionine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Haemophilus influenzae Rd KW20 | 5 | 5 |
| Aggregatibacter aphrophilus NJ8700 | 6 | 4 |
| Pasteurella multocida subsp. multocida str. Pm70 | 8 | 6 |
| Mannheimia succiniciproducens MBEL55E | 7 | 5 |
| Actinobacillus succinogenes 130Z | 6 | 4 |
| Haemophilus somnus 2336 | 7 | 5 |
| Actinobacillus pleuropneumoniae serovar 7 str. AP76 | 6 | 3 |
| Haemophilus ducreyi 35000HP | 4 | 2 |
| Haemophilus parasuis SH0165 | 8 | 5 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| metB |
Gene: HI0086: Cystathionine gamma-synthase (EC 2.5.1.48) |
Gene: NT05HA_1400: Cystathionine gamma-synthase (EC 2.5.1.48) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -61 score = 6.69574 sequence = AGACATCT-(0)-AGATAGCT Gene: PM0995: Cystathionine gamma-synthase (EC 2.5.1.48) |
*
Mannheimia succiniciproducens MBEL55E Site: position = -121 score = 6.0394 sequence = AGAAATTA-(0)-AGATGTTT Gene: MS1627: Cystathionine gamma-synthase (EC 2.5.1.48) |
Gene: Asuc_1846: Cystathionine gamma-synthase (EC 2.5.1.48) |
Gene: HSM_0277: Cystathionine gamma-synthase (EC 2.5.1.48) |
Gene: APP7_0723: Cystathionine gamma-synthase (EC 2.5.1.48) |
|
Gene: HAPS_2273: Cystathionine gamma-synthase (EC 2.5.1.48) |
Cystathionine gamma-synthase (EC 2.5.1.48) |
| CRON 2. | ||||||||||
| metK |
*
Haemophilus influenzae Rd KW20 Site: position = -50 score = 6.67509 sequence = AGCCGTCT-(0)-ATACGTCA Gene: HI1172: S-adenosylmethionine synthetase (EC 2.5.1.6) |
Gene: NT05HA_2370: S-adenosylmethionine synthetase (EC 2.5.1.6) |
Gene: PM1027: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Mannheimia succiniciproducens MBEL55E Site: position = -46 score = 6.18043 sequence = AGCCGTCC-(0)-ATACGTCC Gene: MS0669: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Actinobacillus succinogenes 130Z Site: position = -38 score = 6.80421 sequence = GGCCGTCT-(0)-AAACGGCT Gene: Asuc_0835: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Haemophilus somnus 2336 Site: position = -66 score = 6.93657 sequence = AGCCGTCT-(0)-AGACGTTA Site: position = -58 score = 6.45841 sequence = AGACGTTA-(0)-AAACATCT Gene: HSM_0387: S-adenosylmethionine synthetase (EC 2.5.1.6) |
Gene: APP7_1138: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Haemophilus ducreyi 35000HP Site: position = -162 score = 6.24015 sequence = AGACGTCT-(0)-AGATGTAC Gene: HD0569: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Haemophilus parasuis SH0165 Site: position = -161 score = 5.8083 sequence = AGCCATCT-(0)-AGACGGAA Gene: HAPS_0500: S-adenosylmethionine synthetase (EC 2.5.1.6) |
S-adenosylmethionine synthetase (EC 2.5.1.6) |
| CRON 3. | ||||||||||
| metN |
*
Haemophilus influenzae Rd KW20 Site: position = -61 score = 7.34702 sequence = AGCAATCT-(0)-AGACATCT Gene: HI0621: Methionine ABC transporter ATP-binding protein |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -65 score = 6.82024 sequence = GGCATTCT-(0)-AGACGTCT Gene: NT05HA_2130: Methionine ABC transporter ATP-binding protein |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -62 score = 7.28636 sequence = GGAAATCT-(0)-AGACGTCT Gene: PM1728: Methionine ABC transporter ATP-binding protein |
*
Mannheimia succiniciproducens MBEL55E Site: position = -68 score = 7.32491 sequence = AAACGTCT-(0)-AGACATCT Gene: MS0434: Methionine ABC transporter ATP-binding protein |
*
Actinobacillus succinogenes 130Z Site: position = -51 score = 7.13012 sequence = AGCCATAT-(0)-AGCCGTCT Gene: Asuc_0032: Methionine ABC transporter ATP-binding protein |
*
Haemophilus somnus 2336 Site: position = -61 score = 7.8321 sequence = AGCAATCT-(0)-AGACGTCT Gene: HSM_0571: Methionine ABC transporter ATP-binding protein |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -62 score = 7.8321 sequence = AGCAATCT-(0)-AGACGTCT Gene: APP7_0972: Methionine ABC transporter ATP-binding protein |
*
Haemophilus ducreyi 35000HP Site: position = -56 score = 7.40479 sequence = AGCATTCT-(0)-AGACGTCT Gene: HD1098: Methionine ABC transporter ATP-binding protein |
*
Haemophilus parasuis SH0165 Site: position = -61 score = 7.8321 sequence = AGCAATCT-(0)-AGACGTCT Gene: HAPS_0448: Methionine ABC transporter ATP-binding protein |
Methionine ABC transporter ATP-binding protein |
| metI |
|
Gene: NT05HA_2129: Methionine ABC transporter permease protein |
Gene: PM1729 (deprecated): Methionine ABC transporter permease protein |
Gene: MS0433: Methionine ABC transporter permease protein |
Gene: Asuc_0033: Methionine ABC transporter permease protein |
Gene: HSM_0570: Methionine ABC transporter permease protein |
Gene: APP7_0971: Methionine ABC transporter permease protein |
Gene: HD1099: Methionine ABC transporter permease protein |
Gene: HAPS_0447: Methionine ABC transporter permease protein |
Methionine ABC transporter permease protein |
| metQ |
Gene: HI0620: Methionine ABC transporter substrate-binding protein |
Gene: NT05HA_2128: Methionine ABC transporter substrate-binding protein |
Gene: PM1730: Methionine ABC transporter substrate-binding protein |
Gene: MS0432: Methionine ABC transporter substrate-binding protein |
Gene: Asuc_0034: Methionine ABC transporter substrate-binding protein |
Gene: HSM_0569: Methionine ABC transporter substrate-binding protein |
2
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0970: Methionine ABC transporter substrate-binding protein Gene: APP7_0969: Methionine ABC transporter substrate-binding protein |
Gene: HD1100: Methionine ABC transporter substrate-binding protein |
2
Haemophilus parasuis SH0165 Gene: HAPS_0446: Methionine ABC transporter substrate-binding protein Gene: HAPS_0445: Methionine ABC transporter substrate-binding protein |
Methionine ABC transporter substrate-binding protein |
| CRON 4. | ||||||||||
| metE |
*
Haemophilus influenzae Rd KW20 Site: position = -52 score = 7.86939 sequence = AGACGTTT-(0)-AGCCGTCT Gene: HI1702: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -46 score = 7.86939 sequence = AGACGTTT-(0)-AGCCGTCT Gene: NT05HA_0341: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -56 score = 7.86939 sequence = AGACGTTT-(0)-AGCCGTCT Gene: PM0420: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
|
|
*
Haemophilus somnus 2336 Site: position = -52 score = 8.28113 sequence = AGACGTTT-(0)-AGACGTCT Gene: HSM_1293: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
Gene: APP7_1214: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
|
*
Haemophilus parasuis SH0165 Site: position = -64 score = 7.59565 sequence = AGCCATTT-(0)-AGACGGCT Site: position = -56 score = 7.31677 sequence = AGACGGCT-(0)-AAACGTCT Gene: HAPS_1354: 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase |
| CRON 5. | ||||||||||
| metX |
*
Haemophilus influenzae Rd KW20 Site: position = -87 score = 7.76856 sequence = AGCCGTTT-(0)-AGACGGCT Gene: HI1263: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -163 score = 7.86746 sequence = AGATGTTT-(0)-AGACGTCT Gene: NT05HA_0899: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -70 score = 7.16165 sequence = AGATGTTT-(0)-AGACGTCC Gene: PM0866: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Mannheimia succiniciproducens MBEL55E Site: position = -94 score = 8.24232 sequence = AGCCGTTT-(0)-AGACGTCT Gene: MS0924: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Actinobacillus succinogenes 130Z Site: position = -100 score = 8.24232 sequence = AGCCGTTT-(0)-AGACGTCT Gene: Asuc_1733: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Haemophilus somnus 2336 Site: position = -119 score = 6.39054 sequence = GGCTGTCT-(0)-AGATGTTT Site: position = -111 score = 6.21414 sequence = AGATGTTT-(0)-GGATGGCT Gene: HSM_1561: Homoserine O-acetyltransferase (EC 2.3.1.31) |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -147 score = 7.04368 sequence = AGAACTCT-(0)-AGACGTTT Site: position = -74 score = 7.49184 sequence = AGGCGTTT-(0)-AGACGTCT Site: position = -139 score = 7.80737 sequence = AGACGTTT-(0)-AGACGGCT Gene: APP7_0516: Homoserine O-acetyltransferase (EC 2.3.1.31) |
|
*
Haemophilus parasuis SH0165 Site: position = -107 score = 7.80737 sequence = AGACGTTT-(0)-AGATGTCT Site: position = -123 score = 6.5112 sequence = AGCCATTT-(0)-AAAAATCT Gene: HAPS_0134: Homoserine O-acetyltransferase (EC 2.3.1.31) |
Homoserine O-acetyltransferase (EC 2.3.1.31) |
| CRON 6. | ||||||||||
| metJ |
*
Haemophilus influenzae Rd KW20 Site: position = -83 score = 6.01034 sequence = AGCCGTCT-(0)-AGATTGTT Site: position = -91 score = 7.02742 sequence = GGAAGTTT-(0)-AGCCGTCT Gene: HI0294: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Aggregatibacter aphrophilus NJ8700 Site: position = -85 score = 5.72379 sequence = AGCAGTCT-(0)-TCACGGCT Site: position = -93 score = 6.78595 sequence = AGAAATCT-(0)-AGCAGTCT Gene: NT05HA_1785: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -97 score = 5.56007 sequence = GGATATCT-(0)-AGCAATCT Site: position = -89 score = 6.50624 sequence = AGCAATCT-(0)-TAACGTCT Gene: PM1290: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Mannheimia succiniciproducens MBEL55E Site: position = -26 score = 6.19755 sequence = AGCAGTCT-(0)-TCACGTCT Site: position = -34 score = 5.82751 sequence = ACCTGTTT-(0)-AGCAGTCT Gene: MS1966: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Actinobacillus succinogenes 130Z Site: position = -80 score = 5.33846 sequence = GGCAGTCC-(0)-ATACGTCC Gene: Asuc_0407: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Haemophilus somnus 2336 Site: position = -83 score = 7.00263 sequence = AGCTATCT-(0)-AGAAGTCT Site: position = -75 score = 5.79173 sequence = AGAAGTCT-(0)-AGATTGTT Gene: HSM_0768: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -82 score = 7.1651 sequence = AGAAATCT-(0)-AGACGTCC Gene: APP7_2006: S-adenosylmethionine-responsive transcriptional repressor MetJ |
Gene: HD0675: S-adenosylmethionine-responsive transcriptional repressor MetJ |
Gene: HAPS_2077: S-adenosylmethionine-responsive transcriptional repressor MetJ |
S-adenosylmethionine-responsive transcriptional repressor MetJ |
| CRON 7. | ||||||||||
| metF |
Gene: HI1444: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
Gene: NT05HA_0300: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Pasteurella multocida subsp. multocida str. Pm70 Site: position = -43 score = 7.05679 sequence = AGCCATAT-(0)-AGACATCT Gene: PM0235: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
Gene: MS0787: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
Gene: HSM_1047: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
Gene: APP7_0912: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
*
Haemophilus parasuis SH0165 Site: position = -86 score = 7.6896 sequence = AGCCATCT-(0)-AAACGTCT Gene: HAPS_2275: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |