Regulog GntR2 - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Gluconate utilization
Effector:	D-gluconate
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

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Member of regulog collections

By taxonomy - Bacillales
By TF family - LacI
By effector - D-gluconate
By pathway - Gluconate utilization

Statistics of regulated genes
Genome	Genes	Operons
Anoxybacillus flavithermus WK1
Bacillus amyloliquefaciens FZB42	7	1
Bacillus cereus ATCC 14579
Bacillus clausii KSM-K16	8	1
Bacillus halodurans C-125
Bacillus licheniformis DSM 13
Bacillus pumilus SAFR-032
Bacillus subtilis subsp. subtilis str. 168
Geobacillus kaustophilus HTA426	4	3
Oceanobacillus iheyensis HTE831	9	1
Paenibacillus sp. JDR-2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
gnd	Anoxybacillus flavithermus WK1 Gene: Aflv_0976: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_022170: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC1926: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Bacillus halodurans C-125	Bacillus licheniformis DSM 13 Gene: BLi02567: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Bacillus pumilus SAFR-032 Gene: BPUM_2124: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU23860: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	* Geobacillus kaustophilus HTA426 Site: position = -92 score = 6.55528 sequence = TTCCTAAATCGGTTTAGAAA Gene: GK2344: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Oceanobacillus iheyensis HTE831 Gene: OB0185: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	Paenibacillus sp. JDR-2 Gene: Pjdr2_3810: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)

CRON 2.
gntR2	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_018000: Putative gluconate utilization transcriptional repressor GntR, LacI family	Bacillus cereus ATCC 14579	* Bacillus clausii KSM-K16 Site: position = -32 score = 6.79103 sequence = CTACTAAATCGGTTTAGTAA Gene: ABC3358: Putative gluconate utilization transcriptional repressor GntR, LacI family	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	* Geobacillus kaustophilus HTA426 Site: position = -36 score = 6.37203 sequence = GAACTAAATCGATTTAGTCT Gene: GK1942: Putative gluconate utilization transcriptional repressor GntR, LacI family	* Oceanobacillus iheyensis HTE831 Site: position = -54 score = 6.80988 sequence = TTACTAAATCGATTTACTAA Site: position = -41 score = 5.57204 sequence = TTACTAAACCGTTTTAGTTA Gene: OB2705: Putative gluconate utilization transcriptional repressor GntR, LacI family	Paenibacillus sp. JDR-2	Putative gluconate utilization transcriptional repressor GntR, LacI family
PF01380	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3354: Putative sugar phosphate isomerase, PF01380 family	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2704: Putative sugar phosphate isomerase, PF01380 family	Paenibacillus sp. JDR-2	Putative sugar phosphate isomerase, PF01380 family
kdgA	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017970: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2703: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Paenibacillus sp. JDR-2	2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)
ABC3357	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3357: TRAP-type C4-dicarboxylate transport system, periplasmic component	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2702: TRAP-type C4-dicarboxylate transport system, periplasmic component	Paenibacillus sp. JDR-2	TRAP-type C4-dicarboxylate transport system, periplasmic component
ABC3356	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3356: TRAP-type C4-dicarboxylate transport system, small permease component	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2701: TRAP-type C4-dicarboxylate transport system, small permease component	Paenibacillus sp. JDR-2	TRAP-type C4-dicarboxylate transport system, small permease component
ABC3355	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3355: TRAP-type C4-dicarboxylate transport system, large permease component	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2700: TRAP-type C4-dicarboxylate transport system, large permease component	Paenibacillus sp. JDR-2	TRAP-type C4-dicarboxylate transport system, large permease component
BC2796	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3353: Ribose 5-phosphate isomerase A (EC 5.3.1.6)	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2699: Ribose 5-phosphate isomerase A (EC 5.3.1.6)	Paenibacillus sp. JDR-2	Ribose 5-phosphate isomerase A (EC 5.3.1.6)
kdgK	Anoxybacillus flavithermus WK1	* Bacillus amyloliquefaciens FZB42 Site: position = -53 score = 6.00139 sequence = TTACTAAACCGGTTTACCAA Site: position = -40 score = 5.68324 sequence = TTACCAAACCGATTTAGTCT Gene: RBAM_017950: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3352: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2698: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Paenibacillus sp. JDR-2	2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
PF00215	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC3351: Putative sugar-phosphate decarboxylase, PF00215 family	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831 Gene: OB2697: Putative sugar-phosphate decarboxylase, PF00215 family	Paenibacillus sp. JDR-2	Putative sugar-phosphate decarboxylase, PF00215 family
yjmD	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017960: Predicted mannuronate reductase (EC 1.1.1.131)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC0630: Predicted mannuronate reductase (EC 1.1.1.131)	Bacillus halodurans C-125	Bacillus licheniformis DSM 13 Gene: BLi01355: Predicted mannuronate reductase (EC 1.1.1.131)	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12330: Predicted mannuronate reductase (EC 1.1.1.131)	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Predicted mannuronate reductase (EC 1.1.1.131)
uxuA	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017980: Mannonate dehydratase (EC 4.2.1.8)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC0631: Mannonate dehydratase (EC 4.2.1.8)	Bacillus halodurans C-125 Gene: BH1063: Mannonate dehydratase (EC 4.2.1.8)	Bacillus licheniformis DSM 13 Gene: BLi01356: Mannonate dehydratase (EC 4.2.1.8)	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12340: Mannonate dehydratase (EC 4.2.1.8)	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_0333: Mannonate dehydratase (EC 4.2.1.8)	Mannonate dehydratase (EC 4.2.1.8)
uxuB	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017990: D-mannonate oxidoreductase (EC 1.1.1.57)	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16 Gene: ABC0632: D-mannonate oxidoreductase (EC 1.1.1.57)	Bacillus halodurans C-125 Gene: BH1067: D-mannonate oxidoreductase (EC 1.1.1.57)	Bacillus licheniformis DSM 13 Gene: BLi01357: D-mannonate oxidoreductase (EC 1.1.1.57)	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12350: D-mannonate oxidoreductase (EC 1.1.1.57)	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_0334: D-mannonate oxidoreductase (EC 1.1.1.57)	D-mannonate oxidoreductase (EC 1.1.1.57)
exuT	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_018010: Hexuronate transporter	Bacillus cereus ATCC 14579	Bacillus clausii KSM-K16	Bacillus halodurans C-125	Bacillus licheniformis DSM 13 Gene: BLi01359: Hexuronate transporter	Bacillus pumilus SAFR-032	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU12360: Hexuronate transporter	Geobacillus kaustophilus HTA426	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Hexuronate transporter
gntK	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_031430: Gluconokinase (EC 2.7.1.12)	Bacillus cereus ATCC 14579 Gene: BC2223: Gluconokinase (EC 2.7.1.12)	Bacillus clausii KSM-K16	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032 Gene: BPUM_3602: Gluconokinase (EC 2.7.1.12)	Bacillus subtilis subsp. subtilis str. 168	Geobacillus kaustophilus HTA426 Gene: GK1941: Gluconokinase (EC 2.7.1.12)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Gluconokinase (EC 2.7.1.12)
gntP	Anoxybacillus flavithermus WK1	Bacillus amyloliquefaciens FZB42 Gene: RBAM_031440: GntP family gluconate:proton (H+) symporter	Bacillus cereus ATCC 14579 Gene: BC2224: GntP family gluconate:proton (H+) symporter	Bacillus clausii KSM-K16	Bacillus halodurans C-125	Bacillus licheniformis DSM 13	Bacillus pumilus SAFR-032 Gene: BPUM_3601: GntP family gluconate:proton (H+) symporter	Bacillus subtilis subsp. subtilis str. 168	* Geobacillus kaustophilus HTA426 Site: position = -115 score = 6.60778 sequence = TTACTAAATCGATTTAGCCC Gene: GK1940: GntP family gluconate:proton (H+) symporter	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_3594: GntP family gluconate:proton (H+) symporter	GntP family gluconate:proton (H+) symporter

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GntR2 - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --