Regulog CadR-PbrR - Shewanellaceae

Properties
Regulator type:	Transcription factor
Regulator family:	MerR
Regulation mode:	activator
Biological process:	Lead resistance; Cadmium resistance
Effector:	Lead ion, (Pb2+); Cadmium, ion (Cd2+)
Phylum:	Proteobacteria/Gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 10 sites [see more]

Member of regulog collections

By taxonomy - Shewanellaceae
By trascription factor - CadR-PbrR
By TF family - MerR
By effector - Lead ion, (Pb2+)
By effector - Cadmium, ion (Cd2+)
By pathway - Lead resistance
By pathway - Cadmium resistance

Statistics of regulated genes
Genome	Genes	Operons
Shewanella oneidensis MR-1
Shewanella putrefaciens CN-32	16	4
Shewanella sp W3-18-1	11	4
Shewanella sp ANA-3	1	1
Shewanella sp MR-4
Shewanella sp MR-7
Shewanella baltica OS155
Shewanella denitrificans OS217
Shewanella frigidimarina NCIMB 400	2	1
Shewanella amazonensis SB2B
Shewanella loihica PV-4
Shewanella pealeana ATCC 700345
Shewanella halifaxensis HAW-EB4
Shewanella piezotolerans WP3
Shewanella sediminis HAW-EB3
Shewanella woodyi ATCC 51908

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																	Function

CRON 1.
czcD2	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32* Site: position = -61 score = 5.61753 sequence = ACCTTATAGTGACTTTATAGT Gene: Sputcn32_0221: Co/Zn/Cd efflux protein Site: position = -61 score = 5.61753 sequence = ACCTTATAGTGACTTTATAGT Gene: Sputcn32_0195: Co/Zn/Cd efflux protein	3 Shewanella sp W3-18-1* Site: position = -61 score = 5.61753 sequence = ACCTTATAGTGACTTTATAGT Gene: Sputw3181_0520: Co/Zn/Cd efflux protein Site: position = -61 score = 5.61753 sequence = ACCTTATAGTGACTTTATAGT Gene: Sputw3181_0414: Co/Zn/Cd efflux protein Site: position = -61 score = 5.61753 sequence = ACCTTATAGTGACTTTATAGT Gene: Sputw3181_0439: Co/Zn/Cd efflux protein	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Co/Zn/Cd efflux protein
lspA	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32 Gene: Sputcn32_0222: Lipoprotein signal peptidase (EC 3.4.23.36) Gene: Sputcn32_0196: Lipoprotein signal peptidase (EC 3.4.23.36)	3 Shewanella sp W3-18-1 Gene: Sputw3181_0440: Lipoprotein signal peptidase (EC 3.4.23.36) Gene: Sputw3181_0519: Lipoprotein signal peptidase (EC 3.4.23.36) Gene: Sputw3181_0415: Lipoprotein signal peptidase (EC 3.4.23.36)	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Lipoprotein signal peptidase (EC 3.4.23.36)

CRON 2.
cadA	Shewanella oneidensis MR-1	Shewanella putrefaciens CN-32	Shewanella sp W3-18-1	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	* Shewanella frigidimarina NCIMB 400 Site: position = -61 score = 5.84283 sequence = ACTCTATAGTGACTATAGAGA Gene: Sfri_3462: Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3)	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3)
lspA	Shewanella oneidensis MR-1	Shewanella putrefaciens CN-32	Shewanella sp W3-18-1	Shewanella sp ANA-3 Gene: Shewana3_4320: Lipoprotein signal peptidase (EC 3.4.23.36)	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400 Gene: Sfri_3463: Lipoprotein signal peptidase (EC 3.4.23.36)	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Lipoprotein signal peptidase (EC 3.4.23.36)

CRON 3.
czcD	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32* Site: position = -59 score = 6.35953 sequence = ACTCTATAGTAACTACAGAGT Gene: Sputcn32_0229: Co/Zn/Cd efflux protein Site: position = -59 score = 6.35953 sequence = ACTCTATAGTAACTACAGAGT Gene: Sputcn32_1972: Co/Zn/Cd efflux protein	* Shewanella sp W3-18-1 Site: position = -59 score = 6.35953 sequence = ACTCTATAGTAACTACAGAGT Gene: Sputw3181_1169: Co/Zn/Cd efflux protein	* Shewanella sp ANA-3 Site: position = -57 score = 6.29717 sequence = ACTCTATAGTAACTATAGAGT Gene: Shewana3_4157: Co/Zn/Cd efflux protein	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Co/Zn/Cd efflux protein
Sputcn32_0228	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32 Gene: Sputcn32_0228: hypothetical protein Gene: Sputcn32_1971: hypothetical protein	Shewanella sp W3-18-1 Gene: Sputw3181_1168: hypothetical protein	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	hypothetical protein
czcC	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32 Gene: Sputcn32_0227: Heavy metal RND efflux outer membrane protein Gene: Sputcn32_1970: Heavy metal RND efflux outer membrane protein	Shewanella sp W3-18-1 Gene: Sputw3181_1167: Heavy metal RND efflux outer membrane protein	Shewanella sp ANA-3 Gene: Shewana3_4156: Heavy metal RND efflux outer membrane protein	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400 Gene: Sfri_3455: Heavy metal RND efflux outer membrane protein	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345 Gene: Spea_0385: Heavy metal RND efflux outer membrane protein	Shewanella halifaxensis HAW-EB4 Gene: Shal_3906: Heavy metal RND efflux outer membrane protein	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Heavy metal RND efflux outer membrane protein
czcB	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32 Gene: Sputcn32_0226: Heavy metal efflux RND transporter, membrane fusion protein Gene: Sputcn32_1969: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella sp W3-18-1 Gene: Sputw3181_1166: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella sp ANA-3 Gene: Shewana3_4155: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400 Gene: Sfri_3456: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345 Gene: Spea_0386: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella halifaxensis HAW-EB4 Gene: Shal_3905: Heavy metal efflux RND transporter, membrane fusion protein	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Heavy metal efflux RND transporter, membrane fusion protein
czcA	Shewanella oneidensis MR-1	2 Shewanella putrefaciens CN-32 Gene: Sputcn32_0225: Heavy metal efflux RND transmembrane protein Gene: Sputcn32_1968: Heavy metal efflux RND transmembrane protein	Shewanella sp W3-18-1 Gene: Sputw3181_1165: Heavy metal efflux RND transmembrane protein	Shewanella sp ANA-3 Gene: Shewana3_4154: Heavy metal efflux RND transmembrane protein	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400 Gene: Sfri_3457: Heavy metal efflux RND transmembrane protein	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345 Gene: Spea_0387: Heavy metal efflux RND transmembrane protein	Shewanella halifaxensis HAW-EB4 Gene: Shal_3904: Heavy metal efflux RND transmembrane protein	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Heavy metal efflux RND transmembrane protein
Sputcn32_1967	Shewanella oneidensis MR-1	Shewanella putrefaciens CN-32 Gene: Sputcn32_1967: hypothetical protein	Shewanella sp W3-18-1	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	hypothetical protein
cadA	Shewanella oneidensis MR-1	Shewanella putrefaciens CN-32 Gene: Sputcn32_1966: Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3)	Shewanella sp W3-18-1	Shewanella sp ANA-3	Shewanella sp MR-4	Shewanella sp MR-7	Shewanella baltica OS155	Shewanella denitrificans OS217	Shewanella frigidimarina NCIMB 400	Shewanella amazonensis SB2B	Shewanella loihica PV-4	Shewanella pealeana ATCC 700345	Shewanella halifaxensis HAW-EB4	Shewanella piezotolerans WP3	Shewanella sediminis HAW-EB3	Shewanella woodyi ATCC 51908	Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CadR-PbrR - Shewanellaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --