Statistics of regulated genes

Genome	Genes	Operons
Clostridiales bacterium 1_7_47_FAA	11	4
Clostridium bolteae ATCC BAA-613	4	2
Eubacterium eligens ATCC 27750	1	1
Roseburia intestinalis L1-82	5	3
Ruminococcus gnavus ATCC 29149	6	3
Dorea longicatena DSM 13814	9	3
Blautia hansenii DSM 20583	4	3
Clostridium nexile DSM 1787	9	3
Clostridium scindens ATCC 35704	7	3
Eubacterium rectale ATCC 33656	2	1
Ruminococcus lactaris ATCC 29176	3	1
Dorea formicigenerans ATCC 27755	9	3
Bryantella formatexigens DSM 14469	2	2
Bacteroides pectinophilus ATCC 43243	2	1

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes															Function
CRON 1.
thiT	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750 Gene: EUBELI_01236: Substrate-specific component ThiT of thiamin ECF transporter	* Roseburia intestinalis L1-82 Site: position = -550 score = 70.96 sequence = ACAAATGCTAGGGGT... Gene: ROSINTL182_02990: Substrate-specific component ThiT of thiamin ECF transporter	* Ruminococcus gnavus ATCC 29149 Site: position = -154 score = 61.48 sequence = TTGATAACAAGGGGA... Gene: RUMGNA_01568: Substrate-specific component ThiT of thiamin ECF transporter	Dorea longicatena DSM 13814	* Blautia hansenii DSM 20583 Site: position = -141 score = 64.34 sequence = AGAATAAGAAGGGGA... Gene: BLAHAN_02691: Substrate-specific component ThiT of thiamin ECF transporter	* Clostridium nexile DSM 1787 Site: position = -38 score = 59.97 sequence = CAATTTGCTAGGGGA... Gene: CLONEX_00550: Substrate-specific component ThiT of thiamin ECF transporter	* Clostridium scindens ATCC 35704 Site: position = -188 score = 57.06 sequence = ATAAGACCCATATGG... Gene: CLOSCI_02958: Substrate-specific component ThiT of thiamin ECF transporter	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755	* Bryantella formatexigens DSM 14469 Site: position = -140 score = 67.74 sequence = ATTTTTATGCTAGGG... Gene: BRYFOR_01324: Substrate-specific component ThiT of thiamin ECF transporter	Bacteroides pectinophilus ATCC 43243	Substrate-specific component ThiT of thiamin ECF transporter
CRON 2.
thiM	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100012901: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04494: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_00600: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Ruminococcus gnavus ATCC 29149 Site: position = -201 score = 47.58 sequence = AAATAAAAAACAAGG... Gene: RUMGNA_01198: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Dorea longicatena DSM 13814 Site: position = -280 score = 36.42 sequence = GAAAAGGGGAGTCCG... Gene: DORLON_02556: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Blautia hansenii DSM 20583	Clostridium nexile DSM 1787 Gene: CLONEX_00817: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03982: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Eubacterium rectale ATCC 33656 Site: position = -163 score = 46.82 sequence = AAAAACACAACAGGG... Gene: EUBREC_2530: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Ruminococcus lactaris ATCC 29176	* Dorea formicigenerans ATCC 27755 Site: position = -166 score = 48.84 sequence = ACAACAGGGGGCTTG... Gene: DORFOR_02060: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01349: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00164: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100012896: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_00601: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01197: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Dorea longicatena DSM 13814 Gene: DORLON_02557: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Blautia hansenii DSM 20583 Site: position = -151 score = 67.5 sequence = TTAAAGTCAGCAGGG... Gene: BLAHAN_02471: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	2 Clostridium nexile DSM 1787 Gene: CLONEX_00627: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Gene: CLONEX_00818: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03983: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Eubacterium rectale ATCC 33656 Gene: EUBREC_2529: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Ruminococcus lactaris ATCC 29176 Gene: thiMED: Hydroxyethylthiazole kinase (EC 2.7.1.50) / Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02061: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01348: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Bacteroides pectinophilus ATCC 43243	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
COG0637	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_00602: hypothetical phosphatase/hydrolase	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814	Blautia hansenii DSM 20583	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_03984: hypothetical phosphatase/hydrolase	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02062: hypothetical phosphatase/hydrolase	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	hypothetical phosphatase/hydrolase
thiD	* Clostridiales bacterium 1_7_47_FAA Site: position = -255 score = 51.06 sequence = TAAATAGACAACGGG... Gene: Cbac1_010100007113: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Clostridium bolteae ATCC BAA-613 Site: position = -253 score = 51.79 sequence = TTGTAAATAAACGGG... Gene: CLOBOL_02869: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Eubacterium eligens ATCC 27750 Gene: EUBELI_01399: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	* Roseburia intestinalis L1-82 Site: position = -250 score = 51.57 sequence = AACAAAAAATGGGGT... Gene: ROSINTL182_02417: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01195: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Dorea longicatena DSM 13814 Gene: DORLON_02558: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Blautia hansenii DSM 20583 Gene: BLAHAN_02470: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	2 Clostridium nexile DSM 1787 Gene: CLONEX_00626: Phosphomethylpyrimidine kinase (EC 2.7.4.7) Gene: CLONEX_00819: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03985: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Eubacterium rectale ATCC 33656 Gene: EUBREC_2528: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02063: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01347: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01111: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Phosphomethylpyrimidine kinase (EC 2.7.4.7)
cytX	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100007108: Predicted hydroxymethylpyrimidine transporter CytX	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02868: Predicted hydroxymethylpyrimidine transporter CytX	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_02416: Predicted hydroxymethylpyrimidine transporter CytX	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814 Gene: DORLON_02128: Predicted hydroxymethylpyrimidine transporter CytX	Blautia hansenii DSM 20583	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_03986: Predicted hydroxymethylpyrimidine transporter CytX	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02064: Predicted hydroxymethylpyrimidine transporter CytX	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Predicted hydroxymethylpyrimidine transporter CytX
thiW	* Clostridiales bacterium 1_7_47_FAA Site: position = -179 score = 59.65 sequence = CTAAGTAACAGCAGG... Gene: Cbac1_010100012906: Substrate-specific component ThiW of predicted thiazole ECF transporter	* Clostridium bolteae ATCC BAA-613 Site: position = -118 score = 60.62 sequence = CTAAATGACAACAGG... Gene: CLOBOL_04495: Substrate-specific component ThiW of predicted thiazole ECF transporter	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_02415: Substrate-specific component ThiW of predicted thiazole ECF transporter	Ruminococcus gnavus ATCC 29149	* Dorea longicatena DSM 13814 Site: position = -445 score = 55.29 sequence = TATAAACAGGGGGGA... Gene: DORLON_00841: Substrate-specific component ThiW of predicted thiazole ECF transporter	Blautia hansenii DSM 20583	* Clostridium nexile DSM 1787 Site: position = -166 score = 66.31 sequence = CAAAAACATAGGGGA... Gene: CLONEX_00816: Substrate-specific component ThiW of predicted thiazole ECF transporter	Clostridium scindens ATCC 35704	Eubacterium rectale ATCC 33656 Gene: EUBREC_2526: Substrate-specific component ThiW of predicted thiazole ECF transporter	* Ruminococcus lactaris ATCC 29176 Site: position = -183 score = 44.44 sequence = CGATGAAGAAGGGGA... Gene: RUMLAC_00295: Substrate-specific component ThiW of predicted thiazole ECF transporter	Dorea formicigenerans ATCC 27755	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00165: Substrate-specific component ThiW of predicted thiazole ECF transporter	Substrate-specific component ThiW of predicted thiazole ECF transporter
thiC	* Clostridiales bacterium 1_7_47_FAA Site: position = -220 score = 59.95 sequence = TACAACTACAACAGG... Gene: Cbac1_010100002944: Thiamin biosynthesis protein ThiC	Clostridium bolteae ATCC BAA-613	* Eubacterium eligens ATCC 27750 Site: position = -159 score = 48.77 sequence = TATATTTGCAGGGGA... Gene: EUBELI_00711: Thiamin biosynthesis protein ThiC	* Roseburia intestinalis L1-82 Site: position = -121 score = 59.75 sequence = GAAAACAACGCAGAG... Gene: ROSINTL182_02889: Thiamin biosynthesis protein ThiC	* Ruminococcus gnavus ATCC 29149 Site: position = -194 score = 50.3 sequence = AGAAACAAAAAAGGG... Gene: RUMGNA_03567: Thiamin biosynthesis protein ThiC	2 Dorea longicatena DSM 13814 Gene: DORLON_03029: Thiamin biosynthesis protein ThiC Gene: DORLON_00843: Thiamin biosynthesis protein ThiC	* Blautia hansenii DSM 20583 Site: position = -175 score = 68.71 sequence = AAAAACAACCAGGGA... Gene: BLAHAN_01030: Thiamin biosynthesis protein ThiC	Clostridium nexile DSM 1787 Gene: CLONEX_00820: Thiamin biosynthesis protein ThiC	* Clostridium scindens ATCC 35704 Site: position = -234 score = 57.85 sequence = AGGAACAACAGGGGT... Gene: CLOSCI_03456: Thiamin biosynthesis protein ThiC	Eubacterium rectale ATCC 33656 Gene: EUBREC_2527: Thiamin biosynthesis protein ThiC	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_00297: Thiamin biosynthesis protein ThiC	* Dorea formicigenerans ATCC 27755 Site: position = -220 score = 58.25 sequence = AATTACATACGGGGA... Gene: DORFOR_01676: Thiamin biosynthesis protein ThiC	* Bryantella formatexigens DSM 14469 Site: position = -258 score = 72.29 sequence = AACATAGATACAGGG... Gene: BRYFOR_01350: Thiamin biosynthesis protein ThiC	* Bacteroides pectinophilus ATCC 43243 Site: position = -226 score = 65.85 sequence = TATACAGAATTTGGG... Gene: BACPEC_01112: Thiamin biosynthesis protein ThiC	Thiamin biosynthesis protein ThiC
PF00702	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01196: Haloacid dehalogenase-like hydrolase	Dorea longicatena DSM 13814	Blautia hansenii DSM 20583	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Haloacid dehalogenase-like hydrolase
tenA	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814	Blautia hansenii DSM 20583	* Clostridium nexile DSM 1787 Site: position = -163 score = 49.66 sequence = TGTGTTTGCGAGGGA... Site: position = -323 score = 70.88 sequence = TACTCAAGCAGGGGG... Gene: CLONEX_00625: Thiaminase II (EC 3.5.99.2)	Clostridium scindens ATCC 35704	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Thiaminase II (EC 3.5.99.2)
CRON 3.
thiS	* Clostridiales bacterium 1_7_47_FAA Site: position = -301 score = 57.32 sequence = CCATAAATAGGGGAG... Gene: Cbac1_010100017419: Thiamine biosynthesis protein ThiS	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82 Gene: ROSINTL182_02079: Thiamine biosynthesis protein ThiS	Ruminococcus gnavus ATCC 29149	* Dorea longicatena DSM 13814 Site: position = -327 score = 67.35 sequence = TAGATAAAACACGGG... Gene: DORLON_01209: Thiamine biosynthesis protein ThiS	Blautia hansenii DSM 20583 Gene: BLAHAN_00600: Thiamine biosynthesis protein ThiS	Clostridium nexile DSM 1787	* Clostridium scindens ATCC 35704 Site: position = -319 score = 58.83 sequence = AAATTGAACAGGGGA... Gene: CLOSCI_02950: Thiamine biosynthesis protein ThiS	Eubacterium rectale ATCC 33656 Gene: EUBREC_0225: Thiamine biosynthesis protein ThiS	Ruminococcus lactaris ATCC 29176	* Dorea formicigenerans ATCC 27755 Site: position = -346 score = 57.06 sequence = TTGTAAATAAAAGGG... Gene: DORFOR_02215: Thiamine biosynthesis protein ThiS	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Thiamine biosynthesis protein ThiS
thiF	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100017414: Sulfur carrier protein adenylyltransferase ThiF	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814 Gene: DORLON_01208: Sulfur carrier protein adenylyltransferase ThiF	Blautia hansenii DSM 20583 Gene: BLAHAN_00599: Sulfur carrier protein adenylyltransferase ThiF	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_02951: Sulfur carrier protein adenylyltransferase ThiF	Eubacterium rectale ATCC 33656	Ruminococcus lactaris ATCC 29176	Dorea formicigenerans ATCC 27755	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Sulfur carrier protein adenylyltransferase ThiF
thiG	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100017409: Thiazole biosynthesis protein ThiG	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750 Gene: EUBELI_00477: Thiazole biosynthesis protein ThiG	Roseburia intestinalis L1-82 Gene: ROSINTL182_02081: Thiazole biosynthesis protein ThiG	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814 Gene: DORLON_01207: Thiazole biosynthesis protein ThiG	Blautia hansenii DSM 20583 Gene: BLAHAN_00598: Thiazole biosynthesis protein ThiG	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_02952: Thiazole biosynthesis protein ThiG	Eubacterium rectale ATCC 33656 Gene: EUBREC_0224: Thiazole biosynthesis protein ThiG	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02758: Thiazole biosynthesis protein ThiG	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02214: Thiazole biosynthesis protein ThiG	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Thiazole biosynthesis protein ThiG
thiH	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100017404: Thiazole biosynthesis protein ThiH	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750 Gene: EUBELI_00478: Thiazole biosynthesis protein ThiH	Roseburia intestinalis L1-82 Gene: ROSINTL182_02082: Thiazole biosynthesis protein ThiH	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814 Gene: DORLON_01206: Thiazole biosynthesis protein ThiH	Blautia hansenii DSM 20583 Gene: BLAHAN_00597: Thiazole biosynthesis protein ThiH	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_02953: Thiazole biosynthesis protein ThiH	Eubacterium rectale ATCC 33656 Gene: EUBREC_0223: Thiazole biosynthesis protein ThiH	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02757: Thiazole biosynthesis protein ThiH	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02213: Thiazole biosynthesis protein ThiH	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Thiazole biosynthesis protein ThiH
thiE	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100017399: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Clostridium bolteae ATCC BAA-613	Eubacterium eligens ATCC 27750 Gene: EUBELI_00479: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Roseburia intestinalis L1-82 Gene: ROSINTL182_02083: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Ruminococcus gnavus ATCC 29149	Dorea longicatena DSM 13814 Gene: DORLON_01205: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Blautia hansenii DSM 20583 Gene: BLAHAN_00596: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704 Gene: CLOSCI_02954: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Eubacterium rectale ATCC 33656 Gene: EUBREC_0222: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Ruminococcus lactaris ATCC 29176 Gene: RUMLAC_02756: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Dorea formicigenerans ATCC 27755 Gene: DORFOR_03140: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Bryantella formatexigens DSM 14469	Bacteroides pectinophilus ATCC 43243	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)

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