Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog NiaR - Clostridia-1

Properties
Regulator type: Transcription factor
Regulator family: NiaR
Regulation mode: repressor
Biological process: NAD biosynthesis
Effector: Niacin
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 13 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Clostridium acetobutylicum ATCC 824 3 1
Clostridium beijerincki NCIMB 8052 4 2
Clostridium botulinum A str. ATCC 3502 4 2
Clostridium butyricum 5521 4 2
Clostridium kluyveri DSM 555 4 2
Clostridium novyi NT 4 2
Clostridium perfringens ATCC 13124
Clostridium tetani E88 2 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
niaX
 
Clostridium acetobutylicum ATCC 824
*
Clostridium beijerincki NCIMB 8052

Site:
position = 8
score = 6.08818
sequence = TACTAGTGTATATACATGTGAT

Gene: Cbei_1404: Substrate-specific component NiaX of predicted niacin ECF transporter
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -41
score = 5.99366
sequence = TACTAATGTATATACACTTAAC

Gene: CBO2620: Substrate-specific component NiaX of predicted niacin ECF transporter
*
Clostridium butyricum 5521

Site:
position = -144
score = 6.81581
sequence = TACTAATGTATATACACTAGTA

Gene: CBY_0041: Substrate-specific component NiaX of predicted niacin ECF transporter
*
Clostridium kluyveri DSM 555

Site:
position = -36
score = 6.51927
sequence = TACTGGTGTATATACATTTGTT

Gene: CKL_1488: Substrate-specific component NiaX of predicted niacin ECF transporter
*
Clostridium novyi NT

Site:
position = -42
score = 6.5344
sequence = TACTACTGTATATACAGTAGTA

Gene: NT01CX_1651: Substrate-specific component NiaX of predicted niacin ECF transporter
 
Clostridium perfringens ATCC 13124
*
Clostridium tetani E88

Site:
position = -29
score = 6.81581
sequence = TACTAGTGTATATACATTAGTA

Gene: CTC01003: Substrate-specific component NiaX of predicted niacin ECF transporter
Substrate-specific component NiaX of predicted niacin ECF transporter
 
CRON 2.
nadA
*
Clostridium acetobutylicum ATCC 824

Site:
position = -79
score = 6.0794
sequence = ATTTAATGTATATACACCTGTA

Gene: CAC1025: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium beijerincki NCIMB 8052

Site:
position = -50
score = 6.19092
sequence = CAATGGTGTATATACACCTGTA

Gene: Cbei_0792: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -51
score = 6.21767
sequence = TATATATGTATATACACATGTA

Gene: CBO1448: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium butyricum 5521

Site:
position = -46
score = 6.27705
sequence = AAAAGGTGTATATACACCTGTA

Gene: CBY_3922: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium kluyveri DSM 555

Site:
position = -110
score = 6.39904
sequence = TACTGATGTATATACAGTAGAA

Gene: CKL_0748: Quinolinate synthetase (EC 4.1.99.-)
*
Clostridium novyi NT

Site:
position = -61
score = 5.917
sequence = TTAAGGTGTATATACACATGTG

Gene: NT01CX_0090: Quinolinate synthetase (EC 4.1.99.-)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0382: Quinolinate synthetase (EC 4.1.99.-)
 
Clostridium tetani E88
Quinolinate synthetase (EC 4.1.99.-)
nadB
 
Clostridium acetobutylicum ATCC 824

Gene: CAC1024: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0793: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO1447A: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium butyricum 5521

Gene: CBY_3921: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium kluyveri DSM 555

Gene: CKL_0749: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium novyi NT

Gene: NT01CX_0089: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0383: L-aspartate oxidase (EC 1.4.3.16)
 
Clostridium tetani E88
L-aspartate oxidase (EC 1.4.3.16)
nadC
 
Clostridium acetobutylicum ATCC 824

Gene: CAC1023: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_0794: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO1447: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium butyricum 5521

Gene: CBY_3920: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium kluyveri DSM 555

Gene: CKL_0750: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium novyi NT

Gene: NT01CX_0088: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0384: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
Clostridium tetani E88
Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19)
 
CRON 3.
pncA
 
Clostridium acetobutylicum ATCC 824

Gene: CAC1778: Nicotinamidase (EC 3.5.1.19)
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_2077: Nicotinamidase (EC 3.5.1.19)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO1134: Nicotinamidase (EC 3.5.1.19)
 
Clostridium butyricum 5521

Gene: CBY_1219: Nicotinamidase (EC 3.5.1.19)
 
Clostridium kluyveri DSM 555

Gene: CKL_2731: Nicotinamidase (EC 3.5.1.19)
 
Clostridium novyi NT

Gene: NT01CX_2341: Nicotinamidase (EC 3.5.1.19)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0569: Nicotinamidase (EC 3.5.1.19)
*
Clostridium tetani E88

Site:
position = -56
score = 6.07748
sequence = TTAAAATGTATATACAGATGTA

Gene: CTC00699: Nicotinamidase (EC 3.5.1.19)
Nicotinamidase (EC 3.5.1.19)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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