Regulog CcpA - Clostridia-2

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor (activator)
Biological process:	Carbon catabolism; Carbohydrate metabolism
Effector:	HPr, phosphocarrier protein
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 113 sites [see more]

Member of regulog collections

By trascription factor - CcpA
By taxonomy - Clostridia-2
By TF family - LacI
By effector - HPr, phosphocarrier protein
By pathway - Carbon catabolism
By pathway - Carbohydrate metabolism

Statistics of regulated genes
Genome	Genes	Operons
Clostridium hiranonis DSM 13275	22	13
Clostridium difficile 630	123	59
Clostridium bartlettii DSM 16795	20	11

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes				Function

CRON 1.
rnfC	* Clostridium hiranonis DSM 13275 Site: position = -190 score = 3.61101 sequence = TAGAAACATATATCTT Gene: CLOHIR_01952: Electron transport complex protein RnfC	* Clostridium difficile 630 Site: position = -184 score = 3.8408 sequence = ATGAAAAGGATTGTTT Gene: CD1137: Electron transport complex protein RnfC	* Clostridium bartlettii DSM 16795 Site: position = -100 score = 3.66218 sequence = GATAAATAATTAACAA Gene: CLOBAR_01505: Electron transport complex protein RnfC	Electron transport complex protein RnfC
rnfD	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01953: Electron transport complex protein RnfD	Clostridium difficile 630 Gene: CD1138: Electron transport complex protein RnfD	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01504: Electron transport complex protein RnfD	Electron transport complex protein RnfD
rnfG	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01954: Electron transport complex protein RnfG	Clostridium difficile 630 Gene: CD1139: Electron transport complex protein RnfG	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01503: Electron transport complex protein RnfG	Electron transport complex protein RnfG
rnfE	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01955: Electron transport complex protein RnfE	Clostridium difficile 630 Gene: CD1140: Electron transport complex protein RnfE	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01502: Electron transport complex protein RnfE	Electron transport complex protein RnfE
rnfA	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01956: Electron transport complex protein RnfA	Clostridium difficile 630 Gene: CD1141: Electron transport complex protein RnfA	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01501: Electron transport complex protein RnfA	Electron transport complex protein RnfA
rnfB	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01957: Electron transport complex protein RnfB	Clostridium difficile 630 Gene: CD1142: Electron transport complex protein RnfB	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01500: Electron transport complex protein RnfB	Electron transport complex protein RnfB

CRON 2.
hadA	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -11 score = 4.85451 sequence = AGGAAAACGTTATGCT Gene: CD0395: Hydroxyproline dehydratase putative	Clostridium bartlettii DSM 16795	Hydroxyproline dehydratase putative
hadI	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0396: Benzoyl-CoA reductase subunit BadG (EC 1.3.99.15)	Clostridium bartlettii DSM 16795	Benzoyl-CoA reductase subunit BadG (EC 1.3.99.15)
hadB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0397: Benzoyl-CoA reductase subunit BadE (EC 1.3.99.15)	Clostridium bartlettii DSM 16795	Benzoyl-CoA reductase subunit BadE (EC 1.3.99.15)
hadC	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0398: Subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase	Clostridium bartlettii DSM 16795	Subunit of oxygen-sensitive 2-hydroxyisocaproyl-CoA dehydratase
acdB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0399: Butyryl-CoA dehydrogenase (EC 1.3.99.2)	Clostridium bartlettii DSM 16795	Butyryl-CoA dehydrogenase (EC 1.3.99.2)
etfB1	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0400: Electron transfer flavoprotein, beta subunit	Clostridium bartlettii DSM 16795	Electron transfer flavoprotein, beta subunit
etfA1	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0401: Electron transfer flavoprotein, alpha subunit	Clostridium bartlettii DSM 16795	Electron transfer flavoprotein, alpha subunit

CRON 3.
CD1536	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 232 score = 4.25724 sequence = AAGAAAACGATTTTGT Gene: CD1536: putative electron-transfer protein	Clostridium bartlettii DSM 16795	putative electron-transfer protein
aspB	* Clostridium hiranonis DSM 13275 Site: position = 232 score = 4.86012 sequence = AGGAAAACGATTTCGT Gene: CLOHIR_01291: Pyridine nucleotide-disulphide oxidoreductase family protein	Clostridium difficile 630 Gene: CD1537: Pyridine nucleotide-disulphide oxidoreductase family protein	Clostridium bartlettii DSM 16795	Pyridine nucleotide-disulphide oxidoreductase family protein

CRON 4.
CD1768	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -51 score = 5.07594 sequence = GAGAAAAGGTTTTGTT Gene: CD1768: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 5.
CD1586	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 112 score = 5.10434 sequence = TAGAAAAGGTTATCAT Gene: CD1586: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein
CD1587	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD1587: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)	Clostridium bartlettii DSM 16795	Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
CD1588	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD1588: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)	Clostridium bartlettii DSM 16795	Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)

CRON 6.
spoVS	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -143 score = 4.41326 sequence = AAATAAAGGTTTTCTT Gene: CD1935: Stage V sporulation protein required for dehydratation of the spore core and assembly of the coat (SpoVS)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01875: Stage V sporulation protein required for dehydratation of the spore core and assembly of the coat (SpoVS)	Stage V sporulation protein required for dehydratation of the spore core and assembly of the coat (SpoVS)

CRON 7.
CD1893	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -153 score = 4.30997 sequence = TAGAAATCGTTTAATT Site: position = -76 score = 5.06522 sequence = TATAAAACGTTTTCTT Gene: CD1893: COG3760, similarity to aminoacyl-tRNA editing enzymes YbaK, ProX	Clostridium bartlettii DSM 16795	COG3760, similarity to aminoacyl-tRNA editing enzymes YbaK, ProX

CRON 8.
CD1385	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -110 score = 4.40318 sequence = AAGAAAGCGTTTTGAA Gene: CD1385: Transporter	Clostridium bartlettii DSM 16795	Transporter
CD1386	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -146 score = 4.2291 sequence = AAGAAAAGATATTGTT Gene: CD1386: Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54)	Clostridium bartlettii DSM 16795	Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54)
CD1387	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -127 score = 4.19471 sequence = AAGAACAGATTTTGCT Site: position = -55 score = 3.8618 sequence = TCGAAAAAAATAACTT Gene: CD1387: Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)	Clostridium bartlettii DSM 16795	Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)

CRON 9.
CD1477	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -51 score = 4.66451 sequence = AAGATAACGATTGCTT Gene: CD1477: hypothetical protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02835: hypothetical protein	hypothetical protein
feoA1	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD1478: Ferrous iron transport protein A	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02834: Ferrous iron transport protein A	Ferrous iron transport protein A
feoB1	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD1479: Ferrous iron transport protein B	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02833: Ferrous iron transport protein B	Ferrous iron transport protein B

CRON 10.
spo0A	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -16 score = 3.88536 sequence = AAGAAGATGTTTTTTA Site: position = -41 score = 4.33111 sequence = TGTAAAAAGTTTAGTT Site: position = -134 score = 3.84699 sequence = ATTAAAAAATTTTATT Gene: CD1214: Stage 0 sporulation two-component response regulator (Spo0A)	* Clostridium bartlettii DSM 16795 Site: position = -130 score = 3.91705 sequence = AGTAAATTGTATTCAT Gene: CLOBAR_02247: Stage 0 sporulation two-component response regulator (Spo0A)	Stage 0 sporulation two-component response regulator (Spo0A)

CRON 11.
CD0530	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 11 score = 4.13444 sequence = TAAAAAACATTTTATT Site: position = -79 score = 4.06643 sequence = AGGAAAACGTATTATA Gene: CD0530: Membrane protein, putative	Clostridium bartlettii DSM 16795	Membrane protein, putative
CD0529	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0529: Conserved protein	Clostridium bartlettii DSM 16795	Conserved protein
CD0528	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0528: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)	Clostridium bartlettii DSM 16795	N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)

CRON 12.
gapN	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -75 score = 4.12108 sequence = AAAGAAATGTTTACAT Site: position = -123 score = 4.79517 sequence = AGAAAAACGTTAACTT Gene: CD0580: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Clostridium bartlettii DSM 16795	Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

CRON 13.
CD1321	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 25 score = 4.76644 sequence = AGGAAATAGTTAACTT Gene: CD1321: hypothetical protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02153: hypothetical protein	hypothetical protein
dapG	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01230: Aspartokinase (EC 2.7.2.4)	* Clostridium difficile 630 Site: position = -124 score = 4.10962 sequence = AGAAAAAGGATTTTTT Gene: CD1322: Aspartokinase (EC 2.7.2.4)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02152: Aspartokinase (EC 2.7.2.4)	Aspartokinase (EC 2.7.2.4)

CRON 14.
eutH	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -75 score = 4.15179 sequence = GGGAAAACGATACCAA Gene: CD0742: Ethanolamine permease	Clostridium bartlettii DSM 16795	Ethanolamine permease

CRON 15.
rbsR	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -27 score = 4.33882 sequence = AGTAAAACGGTTTCCT Gene: CD0298: Ribose operon repressor	Clostridium bartlettii DSM 16795	Ribose operon repressor
rbsK	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0299: Ribokinase (EC 2.7.1.15)	Clostridium bartlettii DSM 16795	Ribokinase (EC 2.7.1.15)
rbsB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0300: Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)	Clostridium bartlettii DSM 16795	Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)
rbsA	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0301: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)	Clostridium bartlettii DSM 16795	Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
rbsC	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0302: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)	Clostridium bartlettii DSM 16795	Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)

CRON 16.
CD0201	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 78 score = 4.50666 sequence = GAGAAAATGTTTACAG Gene: CD0201: Chromate transport protein	Clostridium bartlettii DSM 16795	Chromate transport protein

CRON 17.
CD0279A	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -370 score = 4.18945 sequence = AAGAAAACGTTATTAC Site: position = -325 score = 3.92466 sequence = AATAAAAAGATTTTTA Gene: CD0279A: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 18.
virS	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 93 score = 4.87337 sequence = GAGAAAAGGATTTCTA Gene: CD0576: virS protein	Clostridium bartlettii DSM 16795	virS protein

CRON 19.
fba	* Clostridium hiranonis DSM 13275 Site: position = -112 score = 4.75934 sequence = AAGAAAATGTTTGCAA Gene: CLOHIR_01724: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Clostridium difficile 630 Gene: CD0403: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Clostridium bartlettii DSM 16795	Fructose-bisphosphate aldolase class II (EC 4.1.2.13)

CRON 20.
oppB	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -197 score = 4.07605 sequence = AATAAAATAATTTGAT Gene: CD0853: Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)	Clostridium bartlettii DSM 16795	Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)
oppC	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -305 score = 3.96992 sequence = AGCAAAAGGTTTAAAT Site: position = -184 score = 3.62774 sequence = GAAAAAGTTTTTTCTT Site: position = -186 score = 3.75095 sequence = TTGAAAAAGTTTTTTC Gene: CD0854: Peptide ABC transporter, permease protein	Clostridium bartlettii DSM 16795	Peptide ABC transporter, permease protein
oppA	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -302 score = 3.75194 sequence = AGGAATTGGTTTACCA Gene: CD0855: Oligopeptide ABC transporter oligopeptide-binding protein	Clostridium bartlettii DSM 16795	Oligopeptide ABC transporter oligopeptide-binding protein
oppD	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0856: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)	Clostridium bartlettii DSM 16795	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)

CRON 21.
malX	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -141 score = 3.89268 sequence = TTGAAAAAATTTACAG Site: position = -39 score = 4.56583 sequence = TAGAAAACGTTTTAAA Gene: CD1336: PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69) / PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69) / PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
CD1337	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD1337: Transcriptional regulator, RpiR family	Clostridium bartlettii DSM 16795	Transcriptional regulator, RpiR family
glvG	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -142 score = 4.16395 sequence = ATGAAAAAAATTACAA Gene: CD1338: Maltose-6'-phosphate glucosidase (EC 3.2.1.122)	Clostridium bartlettii DSM 16795	Maltose-6'-phosphate glucosidase (EC 3.2.1.122)

CRON 22.
CD0679	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 32 score = 4.17287 sequence = AAGAAATTATTTTGAA Site: position = -66 score = 4.19972 sequence = AGGAAATCGTATGCAT Site: position = -168 score = 4.71915 sequence = ATGATAACATTTTCTT Gene: CD0679: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein
CD0680	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0680: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 23.
pgi	* Clostridium hiranonis DSM 13275 Site: position = -159 score = 4.87279 sequence = GAAAAAACGATTTCTT Site: position = -11 score = 4.0925 sequence = AGAAAAATATTATGAT Gene: CLOHIR_01209: Glucose-6-phosphate isomerase (EC 5.3.1.9)	Clostridium difficile 630 Gene: CD3285: Glucose-6-phosphate isomerase (EC 5.3.1.9)	* Clostridium bartlettii DSM 16795 Site: position = -172 score = 4.22675 sequence = GTGATATCGTTTTCAA Site: position = -208 score = 4.38582 sequence = AGGAAAAATATATCAT Gene: CLOBAR_00319: Glucose-6-phosphate isomerase (EC 5.3.1.9)	Glucose-6-phosphate isomerase (EC 5.3.1.9)

CRON 24.
CD2111	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -6 score = 4.2071 sequence = TAGAAAATGTTTGCAG Gene: CD2111: Glycerol-3-phosphate regulon repressor	Clostridium bartlettii DSM 16795	Glycerol-3-phosphate regulon repressor

CRON 25.
CD2173	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 55 score = 4.03024 sequence = GAGAAAAAATTATAAA Gene: CD2173: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)	Clostridium bartlettii DSM 16795	N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
CD2172	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2172: Amino acid ABC transporter, ATP-binding protein	Clostridium bartlettii DSM 16795	Amino acid ABC transporter, ATP-binding protein

CRON 26.
nanE	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -73 score = 5.5678 sequence = AAGAAAAAGTTTTCAT Gene: CD2241: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Clostridium bartlettii DSM 16795	N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanA	* Clostridium hiranonis DSM 13275 Site: position = -77 score = 4.3206 sequence = AGGAAAACGTTAATTA Gene: CLOHIR_00196: N-acetylneuraminate lyase (EC 4.1.3.3)	Clostridium difficile 630 Gene: CD2240: N-acetylneuraminate lyase (EC 4.1.3.3)	Clostridium bartlettii DSM 16795	N-acetylneuraminate lyase (EC 4.1.3.3)
nanP	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00197: Predicted sialic acid transporter	Clostridium difficile 630 Gene: CD2239: Predicted sialic acid transporter	Clostridium bartlettii DSM 16795	Predicted sialic acid transporter

CRON 27.
CD2283	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -71 score = 4.31051 sequence = TAGAAAAAAATATCAA Gene: CD2283: NtrC family Transcriptional regulator, ATPase domain	Clostridium bartlettii DSM 16795	NtrC family Transcriptional regulator, ATPase domain
CD2282	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2282: PTS system, galactitol-specific IIA component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, galactitol-specific IIA component (EC 2.7.1.69)
CD2281	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -11 score = 3.90834 sequence = AGGAAATTATTATGAA Gene: CD2281: PTS system, IIb component	Clostridium bartlettii DSM 16795	PTS system, IIb component
CD2280	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -101 score = 3.94201 sequence = GAAAAAACATTTTATA Gene: CD2280: PTS system, galactitol-specific IIC component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, galactitol-specific IIC component (EC 2.7.1.69)

CRON 28.
gatA	* Clostridium hiranonis DSM 13275 Site: position = -153 score = 4.74124 sequence = AAAAAAACATTTTCCT Gene: CLOHIR_00174: PTS system, galactitol-specific IIA component (EC 2.7.1.69)	* Clostridium difficile 630 Site: position = -114 score = 5.28208 sequence = GGGAAAACATTTTCTT Gene: CD2327: PTS system, galactitol-specific IIA component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, galactitol-specific IIA component (EC 2.7.1.69)
gatB	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00175: PTS system, galactitol-specific IIB component (EC 2.7.1.69)	Clostridium difficile 630 Gene: CD2326: PTS system, galactitol-specific IIB component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, galactitol-specific IIB component (EC 2.7.1.69)
gatC	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00176: PTS system, galactitol-specific IIC component (EC 2.7.1.69)	Clostridium difficile 630 Gene: CD2325: PTS system, galactitol-specific IIC component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, galactitol-specific IIC component (EC 2.7.1.69)
gatD	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2324: Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251)	Clostridium bartlettii DSM 16795	Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251)
gatD2	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00177: Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251)	Clostridium difficile 630 Gene: CD2323: Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251)	Clostridium bartlettii DSM 16795	Galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251)

CRON 29.
CD2344	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -153 score = 4.30246 sequence = AAGATAAAATTTTTTT Gene: CD2344: putative transport protein	Clostridium bartlettii DSM 16795	putative transport protein
cat1	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2343: Succinyl-CoA:coenzyme A transferase (EC 2.8.3.-)	Clostridium bartlettii DSM 16795	Succinyl-CoA:coenzyme A transferase (EC 2.8.3.-)
sucD	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2342: Succinate-semialdehyde dehydrogenase, CoA-dependent	Clostridium bartlettii DSM 16795	Succinate-semialdehyde dehydrogenase, CoA-dependent

CRON 30.
CD2347	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -31 score = 3.81921 sequence = AAGATAAAATTTATTA Site: position = 175 score = 4.27219 sequence = CAGAAAAGGTTTGCAA Gene: CD2347: Xaa-Pro dipeptidase (EC 3.4.13.9)	Clostridium bartlettii DSM 16795	Xaa-Pro dipeptidase (EC 3.4.13.9)

CRON 31.
porA	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -10 score = 4.0422 sequence = GAGAAAAGGTATGCAA Gene: CD2429: Pyruvate synthase alpha chain (EC 1.2.7.1)	Clostridium bartlettii DSM 16795	Pyruvate synthase alpha chain (EC 1.2.7.1)
porB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2428: Pyruvate synthase subunit porB (EC 1.2.7.1)	Clostridium bartlettii DSM 16795	Pyruvate synthase subunit porB (EC 1.2.7.1)
vorA	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2427: Ketoisovalerate oxidoreductase subunit vorA (EC 1.-.-.-)	Clostridium bartlettii DSM 16795	Ketoisovalerate oxidoreductase subunit vorA (EC 1.-.-.-)

CRON 32.
ung	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02028: Uracil-DNA glycosylase, family 1	* Clostridium difficile 630 Site: position = 46 score = 4.27301 sequence = TTGAAAAAGATTACTA Gene: CD2481: Uracil-DNA glycosylase, family 1	* Clostridium bartlettii DSM 16795 Site: position = -71 score = 3.94066 sequence = TTTAAATAATTTTCTT Gene: CLOBAR_02757: Uracil-DNA glycosylase, family 1	Uracil-DNA glycosylase, family 1

CRON 33.
cstA	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00156: Carbon starvation protein A	2 Clostridium difficile 630* Site: position = -68 score = 4.98958 sequence = TGGAAATAGTTTTCTT Gene: CD2600: Carbon starvation protein A Gene: CD2373: Carbon starvation protein A	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02675: Carbon starvation protein A	Carbon starvation protein A

CRON 34.
CD2625	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 17 score = 4.82564 sequence = AGGAACAGGTTTACTT Site: position = -60 score = 5.06943 sequence = AGGATAACGTTATCAT Gene: CD2625: Perfringolysin O regulator protein PfoR	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01832: Perfringolysin O regulator protein PfoR	Perfringolysin O regulator protein PfoR

CRON 35.
CD2693	* Clostridium hiranonis DSM 13275 Site: position = 18 score = 4.01825 sequence = AAGAAAAAAATTGGCT Gene: CLOHIR_01036: putative sodium:dicarboxylate symporter	* Clostridium difficile 630 Site: position = 3 score = 4.04038 sequence = AAGAAAAAAATAGGTT Gene: CD2693: putative sodium:dicarboxylate symporter	Clostridium bartlettii DSM 16795	putative sodium:dicarboxylate symporter

CRON 36.
brnQ	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01027: Branched-chain amino acid transport system carrier protein	* Clostridium difficile 630 Site: position = -105 score = 4.83738 sequence = GGGAAAACGTTAACAA Gene: CD2702: Branched-chain amino acid transport system carrier protein	* Clostridium bartlettii DSM 16795 Site: position = -75 score = 4.05532 sequence = GGAAAAAGGTTTATAT Gene: CLOBAR_01893: Branched-chain amino acid transport system carrier protein	Branched-chain amino acid transport system carrier protein

CRON 37.
CD2879	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -127 score = 4.98739 sequence = TAGATAAGGTTTTCTT Gene: CD2879: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 38.
licB	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -187 score = 5.23397 sequence = ATGAAAAAGTTTTCTT Gene: CD2884: PTS system, cellobiose-specific IIB component (EC 2.7.1.69)	* Clostridium bartlettii DSM 16795 Site: position = -114 score = 4.42202 sequence = AGGAAAAGGGTTGCAT Gene: CLOBAR_00645: PTS system, cellobiose-specific IIB component (EC 2.7.1.69)	PTS system, cellobiose-specific IIB component (EC 2.7.1.69)
celB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2883: PTS system, cellobiose-specific IIC component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, cellobiose-specific IIC component (EC 2.7.1.69)
celF	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2882: 6-phospho-beta-glucosidase (EC 3.2.1.86)	Clostridium bartlettii DSM 16795	6-phospho-beta-glucosidase (EC 3.2.1.86)
CD2881	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2881: Cellobiose phosphotransferase system YdjC-like protein	Clostridium bartlettii DSM 16795	Cellobiose phosphotransferase system YdjC-like protein
celC	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2880: PTS system, cellobiose-specific IIA component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795	PTS system, cellobiose-specific IIA component (EC 2.7.1.69)

CRON 39.
cggR	* Clostridium hiranonis DSM 13275 Site: position = -163 score = 4.43499 sequence = GATATATCGTTTTCTT Gene: CLOHIR_00836: Central glycolytic genes regulator	* Clostridium difficile 630 Site: position = -80 score = 3.99745 sequence = AAAATAAAAATATCTT Site: position = 108 score = 4.21706 sequence = AGGAGAACATTATCAA Gene: CD3175: Central glycolytic genes regulator	* Clostridium bartlettii DSM 16795 Site: position = -16 score = 3.99745 sequence = AAAATAAAAATATCTT Site: position = -51 score = 3.98976 sequence = GAGAAAACATATTGAA Gene: CLOBAR_00380: Central glycolytic genes regulator	Central glycolytic genes regulator

CRON 40.
CD3218	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00125: hypothetical protein	* Clostridium difficile 630 Site: position = 253 score = 4.27074 sequence = GAGTTAACGTTTTCAA Gene: CD3218: hypothetical protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00652: hypothetical protein	hypothetical protein

CRON 41.
prdA	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00797: D-proline reductase, 23 kDa subunit (EC 1.21.4.1)	* Clostridium difficile 630 Site: position = -294 score = 4.86217 sequence = GAGAAAATGTTTACAA Gene: CD3244: D-proline reductase, 23 kDa subunit (EC 1.21.4.1)	Clostridium bartlettii DSM 16795	D-proline reductase, 23 kDa subunit (EC 1.21.4.1)
CLOHIR_00798	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00798: hypothetical protein	Clostridium difficile 630 Gene: CD3243: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein
prdB	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00800: proline reductase	Clostridium difficile 630 Gene: CD3241: proline reductase	Clostridium bartlettii DSM 16795	proline reductase
prdC	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00801: Proline reductase proprotein, two subunits	Clostridium difficile 630 Gene: CD3240: Proline reductase proprotein, two subunits	Clostridium bartlettii DSM 16795	Proline reductase proprotein, two subunits
CD3239	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD3239: Proline reductase proprotein, two subunits	Clostridium bartlettii DSM 16795	Proline reductase proprotein, two subunits
CD3238	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD3238: Proline reductase proprotein, two subunits	Clostridium bartlettii DSM 16795	Proline reductase proprotein, two subunits
prdF	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00803: Proline racemase (EC 5.1.1.4)	Clostridium difficile 630 Gene: CD3237: Proline racemase (EC 5.1.1.4)	Clostridium bartlettii DSM 16795	Proline racemase (EC 5.1.1.4)

CRON 42.
ldhA	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -207 score = 4.34061 sequence = AAAATAACAATTTCTT Site: position = -319 score = 4.55935 sequence = CAAAAAAAGTTTTCAT Site: position = -130 score = 4.6953 sequence = GGGAAAACAATTTCAA Gene: CD0394: D-lactate dehydrogenase (EC 1.1.1.28)	Clostridium bartlettii DSM 16795	D-lactate dehydrogenase (EC 1.1.1.28)

CRON 43.
CD0850	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 169 score = 4.03349 sequence = TTGAAAATGTTTTGGT Gene: CD0850: hypothetical protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02460: hypothetical protein	hypothetical protein

CRON 44.
spoIIAA	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 88 score = 4.53237 sequence = AAGAAATAGATAACTT Gene: CD0770: anti-sigma F factor antagonist (spoIIAA-2); anti sigma b factor antagonist RsbV	* Clostridium bartlettii DSM 16795 Site: position = 2 score = 3.76563 sequence = GATAAAATGTTATTTA Gene: CLOBAR_01234: anti-sigma F factor antagonist (spoIIAA-2); anti sigma b factor antagonist RsbV	anti-sigma F factor antagonist (spoIIAA-2); anti sigma b factor antagonist RsbV
spoIIAB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD0771: Anti-sigma F factor (EC 2.7.11.1)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01233: Anti-sigma F factor (EC 2.7.11.1)	Anti-sigma F factor (EC 2.7.11.1)
sigF	* Clostridium hiranonis DSM 13275 Site: position = -218 score = 4.02926 sequence = AATAAAAAGTTATTCT Gene: CLOHIR_00712: RNA polymerase sporulation specific sigma factor SigF	Clostridium difficile 630 Gene: CD0772: RNA polymerase sporulation specific sigma factor SigF	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01232: RNA polymerase sporulation specific sigma factor SigF	RNA polymerase sporulation specific sigma factor SigF

CRON 45.
CD0183	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00047: Invasion associated protein p60	* Clostridium difficile 630 Site: position = 3 score = 4.13843 sequence = AAGAAAAAGATATTAA Gene: CD0183: Invasion associated protein p60	Clostridium bartlettii DSM 16795	Invasion associated protein p60

CRON 46.
CD2791	* Clostridium hiranonis DSM 13275 Site: position = -141 score = 4.29873 sequence = GAGAATAAGTTATCAA Gene: CLOHIR_00956: cell surface protein (putative S-layer protein precursor)	* Clostridium difficile 630 Site: position = -131 score = 4.71574 sequence = AAGAAAAAGTTTATAT Gene: CD2791: cell surface protein (putative S-layer protein precursor)	Clostridium bartlettii DSM 16795	cell surface protein (putative S-layer protein precursor)

CRON 47.
dltD	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 184 score = 4.26211 sequence = GAGAAAAGGATATTAT Gene: CD2854: Poly(glycerophosphate chain) D-alanine transfer protein DltD	Clostridium bartlettii DSM 16795	Poly(glycerophosphate chain) D-alanine transfer protein DltD
dltA	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2853: D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13)	Clostridium bartlettii DSM 16795	D-alanine--poly(phosphoribitol) ligase subunit 1 (EC 6.1.1.13)
dltB	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2852: D-alanyl transfer protein DltB	Clostridium bartlettii DSM 16795	D-alanyl transfer protein DltB
dltC	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD2851: D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13)	Clostridium bartlettii DSM 16795	D-alanine--poly(phosphoribitol) ligase subunit 2 (EC 6.1.1.13)

CRON 48.
CD2795	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 12 score = 4.4988 sequence = AAAAAAATATTATCAT Gene: CD2795: N-acetylmuramoyl-L-alanine amidase	Clostridium bartlettii DSM 16795	N-acetylmuramoyl-L-alanine amidase

CRON 49.
CD0830	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -269 score = 4.16325 sequence = AAGAAAAAATTATATA Gene: CD0830: Transporter	Clostridium bartlettii DSM 16795	Transporter

CRON 50.
ptsH	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00990: Phosphocarrier protein of PTS system	* Clostridium difficile 630 Site: position = -55 score = 4.1537 sequence = AGGAAAACAATTTTAA Gene: CD2756: Phosphocarrier protein of PTS system	* Clostridium bartlettii DSM 16795 Site: position = -39 score = 3.82143 sequence = AAAATAAAATTTTTAT Gene: CLOBAR_02362: Phosphocarrier protein of PTS system	Phosphocarrier protein of PTS system

CRON 51.
CD0209	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 0 score = 4.10368 sequence = ATGAAAAAGTTACCAA Gene: CD0209: probable tagatose 6-phosphate kinase	Clostridium bartlettii DSM 16795	probable tagatose 6-phosphate kinase

CRON 52.
tdcB	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01990: Threonine dehydratase (EC 4.3.1.19)	* Clostridium difficile 630 Site: position = -94 score = 4.47874 sequence = TAAAAATCGTTTACAT Gene: CD2514: Threonine dehydratase (EC 4.3.1.19)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00898: Threonine dehydratase (EC 4.3.1.19)	Threonine dehydratase (EC 4.3.1.19)

CRON 53.
CD2385	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = 221 score = 4.02815 sequence = TAGAACTCATTTTGAT Gene: CD2485: Xaa-Pro dipeptidase (EC 3.4.13.9)	Clostridium bartlettii DSM 16795	Xaa-Pro dipeptidase (EC 3.4.13.9)

CRON 54.
grdX	* Clostridium hiranonis DSM 13275 Site: position = 47 score = 4.24687 sequence = AAAAGAAAGTTTTCCT Site: position = 116 score = 4.30184 sequence = TAGAAAATATATTCAT Gene: CLOHIR_00161: GrdX protein	* Clostridium difficile 630 Site: position = 197 score = 4.51437 sequence = AGGAAATCGTTTGGAT Gene: CD2357: GrdX protein	Clostridium bartlettii DSM 16795	GrdX protein
trxB3	* Clostridium hiranonis DSM 13275 Site: position = -97 score = 4.32997 sequence = CGGAAAACATTTACAA Gene: CLOHIR_00162: Thioredoxin reductase (EC 1.8.1.9)	Clostridium difficile 630 Gene: CD2356: Thioredoxin reductase (EC 1.8.1.9)	Clostridium bartlettii DSM 16795	Thioredoxin reductase (EC 1.8.1.9)

CRON 55.
trxA2	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00163: Thioredoxin	* Clostridium difficile 630 Site: position = -6 score = 4.19773 sequence = AAGAAAATGTTAGATT Gene: CD2355: Thioredoxin	Clostridium bartlettii DSM 16795	Thioredoxin

CRON 56.
grdE	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00164: Glycine reductase component B beta subunit (EC 1.21.4.2) / Glycine reductase component B alpha subunit (EC 1.21.4.2)	* Clostridium difficile 630 Site: position = -211 score = 4.36578 sequence = AGAAAAAGGTTTTTAT Gene: CD2354: Glycine reductase component B beta subunit (EC 1.21.4.2) / Glycine reductase component B alpha subunit (EC 1.21.4.2)	Clostridium bartlettii DSM 16795	Glycine reductase component B beta subunit (EC 1.21.4.2) / Glycine reductase component B alpha subunit (EC 1.21.4.2)

CRON 57.
gcvPB	Clostridium hiranonis DSM 13275	2 Clostridium difficile 630* Site: position = -493 score = 4.14417 sequence = GTGAAAATGTTATTTT Gene: CD1657: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2) Gene: CD1658: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)	Clostridium bartlettii DSM 16795	Glycine dehydrogenase [decarboxylating] (glycine cleavage system P2 protein) (EC 1.4.4.2)

CRON 58.
CD3664	* Clostridium hiranonis DSM 13275 Site: position = -31 score = 4.28211 sequence = AAATAAACATTTTCAT Gene: CLOHIR_02123: Aspartate aminotransferase (AspB-4) (EC 2.6.1.1)	* Clostridium difficile 630 Site: position = -31 score = 5.41237 sequence = AAGAAAACATTTTCAT Gene: CD3664: Aspartate aminotransferase (AspB-4) (EC 2.6.1.1)	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_02749: Aspartate aminotransferase (AspB-4) (EC 2.6.1.1) Gene: CLOBAR_01198: Aspartate aminotransferase (AspB-4) (EC 2.6.1.1)	Aspartate aminotransferase (AspB-4) (EC 2.6.1.1)

CRON 59.
rlmH	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02154: LSU m3Psi1915 methyltransferase RlmH	* Clostridium difficile 630 Site: position = 69 score = 4.62605 sequence = AAGAAAAGGCTTTCTA Gene: CD3649: LSU m3Psi1915 methyltransferase RlmH	* Clostridium bartlettii DSM 16795 Site: position = 69 score = 4.58872 sequence = AAAAAAAGGTTATCTA Gene: CLOBAR_00039: LSU m3Psi1915 methyltransferase RlmH	LSU m3Psi1915 methyltransferase RlmH

CRON 60.
CD0177	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -88 score = 4.05402 sequence = TGAAAAAATTTTACTT Gene: CD0177: Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)	Clostridium bartlettii DSM 16795	Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

CRON 61.
tagK	Clostridium hiranonis DSM 13275	* Clostridium difficile 630 Site: position = -68 score = 4.77087 sequence = GTGAAAAGATTTTCAT Gene: CD3076: 1-phosphofructokinase (EC 2.7.1.56)	* Clostridium bartlettii DSM 16795 Site: position = -79 score = 4.20329 sequence = TGAAAATGGTTTTCTA Site: position = -60 score = 4.68233 sequence = TTGAAAAGATTTTCAT Gene: CLOBAR_02382: 1-phosphofructokinase (EC 2.7.1.56)	1-phosphofructokinase (EC 2.7.1.56)
tagT	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD3075: PTS system, fructose-specific IIBC component (EC 2.7.1.69)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02383: PTS system, fructose-specific IIBC component (EC 2.7.1.69)	PTS system, fructose-specific IIBC component (EC 2.7.1.69)
gatY	Clostridium hiranonis DSM 13275	Clostridium difficile 630 Gene: CD3074: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02384: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CcpA - Clostridia-2

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --