Regulog Rex - Thermoanaerobacterales

Properties
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 42 sites [see more]

Member of regulog collections

By trascription factor - Rex
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Statistics of regulated genes
Genome	Genes	Operons
Caldicellulosiruptor saccharolyticus DSM 8903	22	6
Thermoanaerobacter tengcongensis MB4	33	13
Thermoanaerobacter ethanolicus X514	16	11

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Genes				Function

CRON 1.
adhA2	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -46 score = 5.60024 sequence = ATGTTAAAATTATAACAA Gene: Csac_0407: Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing	Thermoanaerobacter tengcongensis MB4	Thermoanaerobacter ethanolicus X514 Gene: Teth514_1935: Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing	Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing

CRON 2.
hydC	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -38 score = 5.22386 sequence = ATGTTAAATTTCTAACAA Gene: Csac_1860: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)	* Thermoanaerobacter tengcongensis MB4 Site: position = -82 score = 4.99253 sequence = ATGATATAATATTAACGA Site: position = -104 score = 5.21615 sequence = TTGTTAAAAAATTAATGA Gene: TTE0890: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)	* Thermoanaerobacter ethanolicus X514 Site: position = -84 score = 4.64604 sequence = ATGATATAATATTGACGA Site: position = -106 score = 5.56654 sequence = TTGTTAAAAATTTAATAA Gene: Teth514_2142: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)	NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)
CLOLEP_03890	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1861: histidine kinase	Thermoanaerobacter tengcongensis MB4 Gene: TTE0891: histidine kinase	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2141: histidine kinase	histidine kinase
hydD	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1862: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)	Thermoanaerobacter tengcongensis MB4 Gene: TTE0892: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2140: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)	NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)
hydB	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1863: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)	Thermoanaerobacter tengcongensis MB4 Gene: TTE0893: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2139: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)	NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)
hydA	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1864: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)	Thermoanaerobacter tengcongensis MB4 Gene: TTE0894: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2138: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)	NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)

CRON 3.
echA	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -45 score = 5.03993 sequence = TTGTTAACAAATTAACTT Gene: Csac_1534: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A	* Thermoanaerobacter tengcongensis MB4 Site: position = -144 score = 5.86399 sequence = TTGTTAAAATAATAACAA Gene: TTE0123: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A
echB	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1535: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B	Thermoanaerobacter tengcongensis MB4 Gene: TTE0124: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B
echC	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1536: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C	Thermoanaerobacter tengcongensis MB4 Gene: TTE0125: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C
echD	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1537: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D	Thermoanaerobacter tengcongensis MB4 Gene: TTE0126: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D
echE	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1538: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E	Thermoanaerobacter tengcongensis MB4 Gene: TTE0127: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E
echF	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1539: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F	Thermoanaerobacter tengcongensis MB4 Gene: TTE0128: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F	Thermoanaerobacter ethanolicus X514	Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F
hypA	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1540: [NiFe] hydrogenase nickel incorporation protein HypA	Thermoanaerobacter tengcongensis MB4 Gene: TTE0129: [NiFe] hydrogenase nickel incorporation protein HypA	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase nickel incorporation protein HypA
hypB	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1541: [NiFe] hydrogenase nickel incorporation-associated protein HypB	Thermoanaerobacter tengcongensis MB4 Gene: TTE0130: [NiFe] hydrogenase nickel incorporation-associated protein HypB	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase nickel incorporation-associated protein HypB
hypF	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1542: [NiFe] hydrogenase metallocenter assembly protein HypF	Thermoanaerobacter tengcongensis MB4 Gene: TTE0131: [NiFe] hydrogenase metallocenter assembly protein HypF	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase metallocenter assembly protein HypF
hypC	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1543: [NiFe] hydrogenase metallocenter assembly protein HypC	Thermoanaerobacter tengcongensis MB4 Gene: TTE0132: [NiFe] hydrogenase metallocenter assembly protein HypC	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase metallocenter assembly protein HypC
hypD	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1544: [NiFe] hydrogenase metallocenter assembly protein HypD	Thermoanaerobacter tengcongensis MB4 Gene: TTE0133: [NiFe] hydrogenase metallocenter assembly protein HypD	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase metallocenter assembly protein HypD
hypE	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1545: [NiFe] hydrogenase metallocenter assembly protein HypE	Thermoanaerobacter tengcongensis MB4 Gene: TTE0134: [NiFe] hydrogenase metallocenter assembly protein HypE	Thermoanaerobacter ethanolicus X514	[NiFe] hydrogenase metallocenter assembly protein HypE

CRON 4.
Csac_2425	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -187 score = 5.52146 sequence = ATGTTATAATATTAACAA Gene: Csac_2425: hypothetical protein	Thermoanaerobacter tengcongensis MB4	Thermoanaerobacter ethanolicus X514	hypothetical protein
hydG	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_2424: [Fe] hydrogenase maturation protein HydG	* Thermoanaerobacter tengcongensis MB4 Site: position = -93 score = 5.46442 sequence = TTGTTGAAAATTTAACAA Gene: TTE1568: [Fe] hydrogenase maturation protein HydG	* Thermoanaerobacter ethanolicus X514 Site: position = -87 score = 5.52708 sequence = TTGTTGAAAAATTAACAA Gene: Teth514_0530: [Fe] hydrogenase maturation protein HydG	[Fe] hydrogenase maturation protein HydG

CRON 5.
rex	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -39 score = 5.2201 sequence = ATGTCAAAAAAATATCAA Gene: Csac_1220: Redox-sensitive transcriptional regulator Rex	* Thermoanaerobacter tengcongensis MB4 Site: position = -60 score = 4.70833 sequence = TTGACAAGAAATTTACAA Gene: TTE0543: Redox-sensitive transcriptional regulator Rex	* Thermoanaerobacter ethanolicus X514 Site: position = -59 score = 5.30617 sequence = TTGACAAAAAATTTACAA Gene: Teth514_0496: Redox-sensitive transcriptional regulator Rex	Redox-sensitive transcriptional regulator Rex

CRON 6.
adhA	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -213 score = 5.19135 sequence = TTGATATAAATTTTACAA Site: position = -246 score = 5.22751 sequence = TTGATTATTTTTTAACAA Gene: TTE0696: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent	2 Thermoanaerobacter ethanolicus X514* Site: position = -31 score = 5.19135 sequence = TTGATATAAATTTTACAA Site: position = -64 score = 5.22751 sequence = TTGATTATTTTTTAACAA Gene: Teth514_0654: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent Site: position = -33 score = 5.72028 sequence = TTGTTATAAATTTAACAA Gene: Teth514_0564: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent	Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent

CRON 7.
adhB	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -96 score = 5.15955 sequence = TTGACAAATTTTTAACTA Site: position = -63 score = 5.08198 sequence = TTGCAAAAAATTTAACAA Gene: TTE0695: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Thermoanaerobacter ethanolicus X514 Site: position = -113 score = 5.38329 sequence = TTGATAAATTTTTAACTA Site: position = -80 score = 5.55872 sequence = TTGTAAAAAATTTAACAA Gene: Teth514_0653: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

CRON 8.
fnorB	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -116 score = 5.51272 sequence = TTGGTAAAAAAATAACAA Gene: TTE0694: ferredoxin-NADP(+) reductase subunit beta	* Thermoanaerobacter ethanolicus X514 Site: position = -113 score = 5.28898 sequence = TTGGCAAAAAAATAACAA Gene: Teth514_0652: ferredoxin-NADP(+) reductase subunit beta	ferredoxin-NADP(+) reductase subunit beta
fnorA	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4 Gene: TTE0693: ferredoxin-NADP(+) reductase subunit alpha	Thermoanaerobacter ethanolicus X514 Gene: Teth514_0651: ferredoxin-NADP(+) reductase subunit alpha	ferredoxin-NADP(+) reductase subunit alpha

CRON 9.
TTE0622	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -73 score = 5.1963 sequence = TTGATAAATATTTGACAT Gene: TTE0622: membrane spanning protein	* Thermoanaerobacter ethanolicus X514 Site: position = -74 score = 4.77146 sequence = TTGATATTTATTTGACAT Gene: Teth514_0252: membrane spanning protein	membrane spanning protein

CRON 10.
COG4739	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -94 score = 5.54049 sequence = TTGATAAAATTTTATCAA Gene: TTE2157: Ferredoxin domain containing protein	* Thermoanaerobacter ethanolicus X514 Site: position = -98 score = 5.54049 sequence = TTGATAAAATTTTATCAA Gene: Teth514_0970: Ferredoxin domain containing protein	Ferredoxin domain containing protein

CRON 11.
noxE	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -107 score = 4.77374 sequence = TTGATATTTTATTGACAT Site: position = -158 score = 4.51657 sequence = TTGTCAACAAAAAATCAA Gene: TTE1884: NADH oxidase (EC 1.6.99.3)	* Thermoanaerobacter ethanolicus X514 Site: position = -162 score = 5.01643 sequence = TTGTTAATAAAAAATCAA Site: position = -112 score = 4.77374 sequence = TTGATATTTTATTGACAT Gene: Teth514_1131: NADH oxidase (EC 1.6.99.3)	NADH oxidase (EC 1.6.99.3)

CRON 12.
PF00724	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -35 score = 5.48061 sequence = CTGTTAATAAATTAACAA Gene: TTE2131: NADH:flavin oxidoreductase	Thermoanaerobacter ethanolicus X514	NADH:flavin oxidoreductase

CRON 13.
bcd	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -33 score = 5.44384 sequence = ATGTTAAAAAAATATCAA Gene: TTE0545: Butyryl-CoA dehydrogenase (EC 1.3.99.2)	Thermoanaerobacter ethanolicus X514	Butyryl-CoA dehydrogenase (EC 1.3.99.2)
etfB	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4 Gene: TTE0546: Electron transfer flavoprotein, beta subunit	Thermoanaerobacter ethanolicus X514	Electron transfer flavoprotein, beta subunit
etfA	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4 Gene: TTE0547: Electron transfer flavoprotein, alpha subunit	Thermoanaerobacter ethanolicus X514	Electron transfer flavoprotein, alpha subunit
hbd	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4 Gene: TTE0548: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)	Thermoanaerobacter ethanolicus X514	3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
acoA	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4 Gene: TTE0549: Acetyl-CoA acetyltransferase (EC 2.3.1.9)	Thermoanaerobacter ethanolicus X514	Acetyl-CoA acetyltransferase (EC 2.3.1.9)

CRON 14.
adhE	Caldicellulosiruptor saccharolyticus DSM 8903	Thermoanaerobacter tengcongensis MB4	* Thermoanaerobacter ethanolicus X514 Site: position = -151 score = 5.37205 sequence = TTGTTAAATGAATAACAA Site: position = -32 score = 5.39797 sequence = TTGTTAAATTATTAACAC Gene: Teth514_0627: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)

CRON 15.
ndh	Caldicellulosiruptor saccharolyticus DSM 8903	* Thermoanaerobacter tengcongensis MB4 Site: position = -58 score = 4.9885 sequence = ATGATAAAATATTGACTA Site: position = -34 score = 5.246 sequence = TTGTTATAATTATATCAA Gene: TTE2486: NADH dehydrogenase (EC 1.6.99.3)	Thermoanaerobacter ethanolicus X514	NADH dehydrogenase (EC 1.6.99.3)

CRON 16.
adhA3	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -30 score = 5.05037 sequence = ATGTTAATTTTTTAACAG Site: position = -53 score = 4.73097 sequence = ATGTTTATATAATAATAA Site: position = -70 score = 4.81894 sequence = TTGACAAAAAACAAACAA Gene: Csac_0622: Alcohol dehydrogenase (EC 1.1.1.1), iron-containing	Thermoanaerobacter tengcongensis MB4	Thermoanaerobacter ethanolicus X514	Alcohol dehydrogenase (EC 1.1.1.1), iron-containing

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Rex - Thermoanaerobacterales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --