Regulog GlnR - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	MerR
Regulation mode:	repressor
Biological process:	Nitrogen assimilation
Effector:	Phosphorylated NtrB, signal histidine kinase
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 32 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By TF family - MerR
By effector - Phosphorylated NtrB, signal histidine kinase
By pathway - Nitrogen assimilation

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367	7	3
Lactobacillus casei ATCC 334	6	4
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1	6	4
Lactobacillus reuteri JCM 1112
Lactobacillus rhamnosus GG	6	4
Lactobacillus sakei subsp. sakei 23K	2	1
Lactobacillus salivarius subsp. salivarius UCC118	10	5
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	8	4
Oenococcus oeni PSU-1	3	2
Pediococcus pentosaceus ATCC 25745	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
gluQ	Lactobacillus acidophilus NCFM Gene: LBA0578: Glutamate ABC transporter, ATP-binding protein	* Lactobacillus brevis ATCC 367 Site: position = -260 score = 5.70621 sequence = GTGTTAGAATTTATAACAT Gene: LVIS_1775: Glutamate ABC transporter, ATP-binding protein	Lactobacillus casei ATCC 334 Gene: LSEI_2022: Glutamate ABC transporter, ATP-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0458: Glutamate ABC transporter, ATP-binding protein	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_0598: Glutamate ABC transporter, ATP-binding protein	Lactobacillus johnsonii NCC 533 Gene: LJ0753: Glutamate ABC transporter, ATP-binding protein	Lactobacillus plantarum WCFS1 Gene: lp_0878: Glutamate ABC transporter, ATP-binding protein	Lactobacillus reuteri JCM 1112 Gene: LAR_1420: Glutamate ABC transporter, ATP-binding protein	Lactobacillus rhamnosus GG Gene: LGG_02009: Glutamate ABC transporter, ATP-binding protein	Lactobacillus sakei subsp. sakei 23K	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -201 score = 5.42781 sequence = TTGTTAGATTTTCTAACAA Site: position = -161 score = 4.75879 sequence = ATGTAACCTAATATAACAT Gene: LSL_1446: Glutamate ABC transporter, ATP-binding protein	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -152 score = 5.58795 sequence = TTGTTATAAAACCTCACAT Gene: LEUM_1936: Glutamate ABC transporter, ATP-binding protein	Oenococcus oeni PSU-1 Gene: OEOE_1634: Glutamate ABC transporter, ATP-binding protein	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0389: Glutamate ABC transporter, ATP-binding protein	Glutamate ABC transporter, ATP-binding protein
gluH	Lactobacillus acidophilus NCFM Gene: LBA0579: Glutamate ABC transporter, substrate-binding protein	Lactobacillus brevis ATCC 367 Gene: LVIS_1774: Glutamate ABC transporter, substrate-binding protein	Lactobacillus casei ATCC 334 Gene: LSEI_2021: Glutamate ABC transporter, substrate-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0459: Glutamate ABC transporter, substrate-binding protein	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_0599: Glutamate ABC transporter, substrate-binding protein	Lactobacillus johnsonii NCC 533 Gene: LJ0754: Glutamate ABC transporter, substrate-binding protein	Lactobacillus plantarum WCFS1 Gene: lp_0881: Glutamate ABC transporter, substrate-binding protein	Lactobacillus reuteri JCM 1112 Gene: LAR_1421: Glutamate ABC transporter, substrate-binding protein	Lactobacillus rhamnosus GG Gene: LGG_02008: Glutamate ABC transporter, substrate-binding protein	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1445: Glutamate ABC transporter, substrate-binding protein	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1935: Glutamate ABC transporter, substrate-binding protein	Oenococcus oeni PSU-1 Gene: OEOE_1633: Glutamate ABC transporter, substrate-binding protein	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0390: Glutamate ABC transporter, substrate-binding protein	Glutamate ABC transporter, substrate-binding protein
gluM	Lactobacillus acidophilus NCFM Gene: LBA0581: Glutamate ABC transporter, permease protein 1	Lactobacillus brevis ATCC 367 Gene: LVIS_1773: Glutamate ABC transporter, permease protein 1	Lactobacillus casei ATCC 334 Gene: LSEI_2020: Glutamate ABC transporter, permease protein 1	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0460: Glutamate ABC transporter, permease protein 1	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_0600: Glutamate ABC transporter, permease protein 1	Lactobacillus johnsonii NCC 533 Gene: LJ0755: Glutamate ABC transporter, permease protein 1	Lactobacillus plantarum WCFS1 Gene: lp_0882: Glutamate ABC transporter, permease protein 1	Lactobacillus reuteri JCM 1112 Gene: LAR_1422: Glutamate ABC transporter, permease protein 1	Lactobacillus rhamnosus GG Gene: LGG_02007: Glutamate ABC transporter, permease protein 1	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1444: Glutamate ABC transporter, permease protein 1	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1934: Glutamate ABC transporter, permease protein 1	Oenococcus oeni PSU-1 Gene: OEOE_1632: Glutamate ABC transporter, permease protein 1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0391: Glutamate ABC transporter, permease protein 1	Glutamate ABC transporter, permease protein 1
gluP	Lactobacillus acidophilus NCFM Gene: LBA0582: Glutamate ABC transporter, permease protein 2	Lactobacillus brevis ATCC 367 Gene: LVIS_1772: Glutamate ABC transporter, permease protein 2	Lactobacillus casei ATCC 334 Gene: LSEI_2019: Glutamate ABC transporter, permease protein 2	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0461: Glutamate ABC transporter, permease protein 2	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_0601: Glutamate ABC transporter, permease protein 2	Lactobacillus johnsonii NCC 533 Gene: LJ0756: Glutamate ABC transporter, permease protein 2	Lactobacillus plantarum WCFS1 Gene: lp_0883: Glutamate ABC transporter, permease protein 2	Lactobacillus reuteri JCM 1112 Gene: LAR_1423: Glutamate ABC transporter, permease protein 2	Lactobacillus rhamnosus GG Gene: LGG_02006: Glutamate ABC transporter, permease protein 2	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1443: Glutamate ABC transporter, permease protein 2	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1933: Glutamate ABC transporter, permease protein 2	Oenococcus oeni PSU-1 Gene: OEOE_1631: Glutamate ABC transporter, permease protein 2	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0392: Glutamate ABC transporter, permease protein 2	Glutamate ABC transporter, permease protein 2

CRON 2.
glnR	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = -82 score = 6.27404 sequence = ATGTCAGAAAACCTAACAT Gene: LVIS_0991: Nitrogen metabolism transcriptional regulator, MerR family	* Lactobacillus casei ATCC 334 Site: position = -79 score = 5.95751 sequence = ATGTCAGAAAAGCTTACAT Gene: LSEI_1653: Nitrogen metabolism transcriptional regulator, MerR family	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -82 score = 5.42409 sequence = GTGTGATATTTTCTAACAT Gene: lp_1580: Nitrogen metabolism transcriptional regulator, MerR family	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -79 score = 5.99062 sequence = ATGTAAGAAAACCTTACAT Gene: LGG_01697: Nitrogen metabolism transcriptional regulator, MerR family	* Lactobacillus sakei subsp. sakei 23K Site: position = -77 score = 6.27404 sequence = ATGTCAGAAAACCTAACAT Gene: LSA1322: Nitrogen metabolism transcriptional regulator, MerR family	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -83 score = 5.38921 sequence = GTGTAAGAAAATATTACAT Gene: LSL_0557: Nitrogen metabolism transcriptional regulator, MerR family	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -80 score = 5.89142 sequence = ATGTTAGAAAACCTGACAC Gene: LEUM_0716: Nitrogen metabolism transcriptional regulator, MerR family	* Oenococcus oeni PSU-1 Site: position = -67 score = 5.7377 sequence = ATGTTAGCTTTCCTAACAT Gene: OEOE_0951: Nitrogen metabolism transcriptional regulator, MerR family	* Pediococcus pentosaceus ATCC 25745 Site: position = -81 score = 6.1696 sequence = ATGTTAGAAAATGTAACAT Gene: PEPE_0738: Nitrogen metabolism transcriptional regulator, MerR family	Nitrogen metabolism transcriptional regulator, MerR family
glnA	Lactobacillus acidophilus NCFM Gene: LBA1501: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus brevis ATCC 367 Gene: LVIS_0990: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus casei ATCC 334 Gene: LSEI_1652: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1368: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus fermentum IFO 3956 Gene: LAF_1275: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus helveticus DPC 4571 Gene: lhv_1558: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus johnsonii NCC 533 Gene: LJ1614: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus plantarum WCFS1 Gene: lp_1581: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus reuteri JCM 1112 Gene: LAR_1135: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus rhamnosus GG Gene: LGG_01696: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus sakei subsp. sakei 23K Gene: LSA1321: Glutamine synthetase type I (EC 6.3.1.2)	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0558: Glutamine synthetase type I (EC 6.3.1.2)	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0717: Glutamine synthetase type I (EC 6.3.1.2)	Oenococcus oeni PSU-1 Gene: OEOE_0952: Glutamine synthetase type I (EC 6.3.1.2)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0739: Glutamine synthetase type I (EC 6.3.1.2)	Glutamine synthetase type I (EC 6.3.1.2)

CRON 3.
ansB	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -90 score = 4.88076 sequence = TTGTCAGACTACCTAACAA Gene: LSEI_2863: Aspartate ammonia-lyase (EC 4.3.1.1)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -44 score = 5.57736 sequence = ATGTTAGAAGATATAACAT Gene: lp_2830: Aspartate ammonia-lyase (EC 4.3.1.1)	Lactobacillus reuteri JCM 1112	* Lactobacillus rhamnosus GG Site: position = -90 score = 4.97125 sequence = TTGTTAGACTAGCTCACAT Gene: LGG_02872: Aspartate ammonia-lyase (EC 4.3.1.1)	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -81 score = 4.86158 sequence = GTGTCATAAAACTTAACAA Gene: LEUM_0153: Aspartate ammonia-lyase (EC 4.3.1.1)	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Aspartate ammonia-lyase (EC 4.3.1.1)

CRON 4.
glnP	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -172 score = 5.33503 sequence = ATGTCAATTAATCTAACAT Gene: LSEI_2849: Glutamine ABC transporter, permease and substrate-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_2019: Glutamine ABC transporter, permease and substrate-binding protein	Lactobacillus fermentum IFO 3956 Gene: LAF_0069: Glutamine ABC transporter, permease and substrate-binding protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -54 score = 5.49468 sequence = ATGTTATATTTTATGACAT Gene: lp_0802: Glutamine ABC transporter, permease and substrate-binding protein	Lactobacillus reuteri JCM 1112 Gene: LAR_0092: Glutamine ABC transporter, permease and substrate-binding protein	* Lactobacillus rhamnosus GG Site: position = -256 score = 6.08519 sequence = ATGTAAGAAAAGCTAACAT Gene: LGG_02862: Glutamine ABC transporter, permease and substrate-binding protein	Lactobacillus sakei subsp. sakei 23K Gene: LSA1497: Glutamine ABC transporter, permease and substrate-binding protein	2 Lactobacillus salivarius subsp. salivarius UCC118* Site: position = -44 score = 4.56029 sequence = ATGAGATATATTTTAACAT Gene: LSL_0062: Glutamine ABC transporter, permease and substrate-binding protein Site: position = -157 score = 4.43552 sequence = TTGTCACTTTATATAACAT Gene: LSL_0581: Glutamine ABC transporter, permease and substrate-binding protein	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0438: Glutamine ABC transporter, permease and substrate-binding protein	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -34 score = 5.81956 sequence = ATGTTAGGTTATCTAACAT Gene: PEPE_1068: Glutamine ABC transporter, permease and substrate-binding protein	Glutamine ABC transporter, permease and substrate-binding protein
glnQ	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_2848: Glutamine ABC transporter, ATP-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_2020: Glutamine ABC transporter, ATP-binding protein	Lactobacillus fermentum IFO 3956 Gene: LAF_0070: Glutamine ABC transporter, ATP-binding protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0803: Glutamine ABC transporter, ATP-binding protein	Lactobacillus reuteri JCM 1112 Gene: LAR_0093: Glutamine ABC transporter, ATP-binding protein	Lactobacillus rhamnosus GG Gene: LGG_02861: Glutamine ABC transporter, ATP-binding protein	Lactobacillus sakei subsp. sakei 23K Gene: LSA1496: Glutamine ABC transporter, ATP-binding protein	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_0582: Glutamine ABC transporter, ATP-binding protein	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0439: Glutamine ABC transporter, ATP-binding protein	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_1067: Glutamine ABC transporter, ATP-binding protein	Glutamine ABC transporter, ATP-binding protein

CRON 5.
nrgA	Lactobacillus acidophilus NCFM Gene: LBA0473: Ammonium transporter	* Lactobacillus brevis ATCC 367 Site: position = -42 score = 6.02549 sequence = GTGTTAGAATTCCTAACAT Site: position = -177 score = 5.28167 sequence = ATGTCATAAAAATTAACAT Gene: LVIS_0844: Ammonium transporter	* Lactobacillus casei ATCC 334 Site: position = -173 score = 4.73547 sequence = ATGTCACATAAGCTAACGC Gene: LSEI_0653: Ammonium transporter	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1541: Ammonium transporter	Lactobacillus fermentum IFO 3956 Gene: LAF_1683: Ammonium transporter	Lactobacillus helveticus DPC 4571 Gene: lhv_2090: Ammonium transporter	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -46 score = 6.21067 sequence = ATGTTATAATTTCTAACAT Gene: lp_0349: Ammonium transporter	Lactobacillus reuteri JCM 1112 Gene: LAR_1328: Ammonium transporter	* Lactobacillus rhamnosus GG Site: position = -174 score = 5.36855 sequence = ATGTTATATAAGCTGACGT Gene: LGG_00633: Ammonium transporter	Lactobacillus sakei subsp. sakei 23K	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -94 score = 5.37565 sequence = ATGTCATAAAAAGTTACAT Site: position = -41 score = 5.38035 sequence = ATGTTATAATTTTTGACAT Gene: LSL_0235: Ammonium transporter	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -89 score = 5.34273 sequence = ATGTAAGAAAAGCTACCAC Gene: LEUM_0776: Ammonium transporter	* Oenococcus oeni PSU-1 Site: position = -62 score = 4.80128 sequence = TTGTTATATTAGTTAACAC Gene: OEOE_1679: Ammonium transporter	Pediococcus pentosaceus ATCC 25745	Ammonium transporter

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GlnR - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --