Regulog NrtR - Streptococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	NrtR
Regulation mode:	repressor
Biological process:	NAD biosynthesis
Effector:	Adenosine diphosphate ribose
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

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Member of regulog collections

By taxonomy - Streptococcaceae
By trascription factor - NrtR
By TF family - NrtR
By effector - Adenosine diphosphate ribose
By pathway - NAD biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11
Lactococcus lactis subsp. lactis Il1403
Streptococcus agalactiae 2603V/R
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34
Streptococcus gordonii str. Challis substr. CH1	3	1
Streptococcus mitis B6	3	1
Streptococcus mutans UA159
Streptococcus pneumoniae TIGR4
Streptococcus pyogenes M1 GAS
Streptococcus sanguinis SK36	3	1
Streptococcus suis 05ZYH33	4	1
Streptococcus thermophilus CNRZ1066	2	1
Streptococcus uberis 0140J

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
nadR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -121 score = 4.6622 sequence = ATATTTGAGTTTAAAAATATT Site: position = -60 score = 7.20481 sequence = ATAGTTTATAATAAAAACATA Gene: SGO_1997: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)	* Streptococcus mitis B6 Site: position = -47 score = 6.9006 sequence = ATAGTTTATAATAAAAATATC Site: position = -84 score = 4.9128 sequence = ATAAAAAATAATAAAAACCTA Gene: smi_2044: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	* Streptococcus sanguinis SK36 Site: position = -61 score = 7.08926 sequence = ATAGTTTATAATAAAATCATA Gene: SSA_2195: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)	2 Streptococcus suis 05ZYH33* Site: position = -90 score = 4.60859 sequence = ATCTTTTTATAAAAAAATATA Gene: SSU05_1974: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22) Gene: SSU05_1973: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)	* Streptococcus thermophilus CNRZ1066 Site: position = -26 score = 5.84173 sequence = TTACTATATTTAAAAAGGATA Gene: str0429: Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)	Streptococcus uberis 0140J	Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)
pnuC	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1996: Ribosyl nicotinamide transporter, PnuC-like	Streptococcus mitis B6 Gene: smi_2043: Ribosyl nicotinamide transporter, PnuC-like	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_2194: Ribosyl nicotinamide transporter, PnuC-like	Streptococcus suis 05ZYH33 Gene: SSU05_1972: Ribosyl nicotinamide transporter, PnuC-like	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Ribosyl nicotinamide transporter, PnuC-like
nrtR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1995: NAD biosynthesis transcriptional regulator NrtR, NrtR family	Streptococcus mitis B6 Gene: smi_2042: NAD biosynthesis transcriptional regulator NrtR, NrtR family	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_2193: NAD biosynthesis transcriptional regulator NrtR, NrtR family	Streptococcus suis 05ZYH33 Gene: SSU05_1971: NAD biosynthesis transcriptional regulator NrtR, NrtR family	Streptococcus thermophilus CNRZ1066 Gene: str0428: NAD biosynthesis transcriptional regulator NrtR, NrtR family	Streptococcus uberis 0140J	NAD biosynthesis transcriptional regulator NrtR, NrtR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NrtR - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --