Regulog MalR - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Maltose utilization; Maltodextrin utilization
Effector:	Maltose
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 11 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By TF family - LacI
By effector - Maltose
By pathway - Maltose utilization
By pathway - Maltodextrin utilization

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367	2	1
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956	3	1
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1	10	3
Lactobacillus reuteri JCM 1112	3	1
Lactobacillus rhamnosus GG
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118	4	1
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	7	2
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745	3	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
malT	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = -93 score = 6.22689 sequence = TTGCGCAATCGGTTGCATTA Gene: LVIS_0357: Predicted maltose/maltodextrin permease	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -122 score = 6.57432 sequence = TTGTGCAAACGGTTGCACAA Gene: LAF_0024: Predicted maltose/maltodextrin permease	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -87 score = 6.2622 sequence = TCACGCAAACGCTTGCATAA Gene: lp_1729: Predicted maltose/maltodextrin permease	* Lactobacillus reuteri JCM 1112 Site: position = -124 score = 6.04445 sequence = TTGCGCAAGCGGTTGCGCAA Gene: LAR_0051: Predicted maltose/maltodextrin permease	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -117 score = 6.2622 sequence = TATCGCAAACGGTTGCAAAA Gene: LSL_1282: Predicted maltose/maltodextrin permease	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293* Site: position = -43 score = 5.49435 sequence = CAATGTAAACGGTTACAAAA Gene: LEUM_0893: Predicted maltose/maltodextrin permease Site: position = -186 score = 6.10746 sequence = TTGTGCAAACGCTTCCATTA Gene: LEUM_0994: Predicted maltose/maltodextrin permease	Oenococcus oeni PSU-1	* Pediococcus pentosaceus ATCC 25745 Site: position = -86 score = 6.13413 sequence = AAGTGCAAACGCTTGCACAA Gene: PEPE_0968: Predicted maltose/maltodextrin permease	Predicted maltose/maltodextrin permease
galM	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1731: Aldose 1-epimerase	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1281: Aldose 1-epimerase	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0996: Aldose 1-epimerase	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Aldose 1-epimerase
mapA	Lactobacillus acidophilus NCFM Gene: LBA1870: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus brevis ATCC 367 Gene: LVIS_0358: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus casei ATCC 334 Gene: LSEI_0982: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0025: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus helveticus DPC 4571 Gene: lhv_2000: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus johnsonii NCC 533 Gene: LJ0213: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus plantarum WCFS1 Gene: lp_1730: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus reuteri JCM 1112 Gene: LAR_0052: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus rhamnosus GG Gene: LGG_00945: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1280: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0894: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64) Gene: LEUM_0995: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0967: Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)	Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)
pgmB	Lactobacillus acidophilus NCFM Gene: LBA1869: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus brevis ATCC 367 Gene: LVIS_1925: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus casei ATCC 334 Gene: LSEI_0983: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0026: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus helveticus DPC 4571 Gene: lhv_1999: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus johnsonii NCC 533 Gene: LJ0214: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112 Gene: LAR_0053: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus rhamnosus GG Gene: LGG_00946: Beta-phosphoglucomutase (EC 5.4.2.6)	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1279: Beta-phosphoglucomutase (EC 5.4.2.6)	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0895: Beta-phosphoglucomutase (EC 5.4.2.6) Gene: LEUM_0997: Beta-phosphoglucomutase (EC 5.4.2.6)	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0966: Beta-phosphoglucomutase (EC 5.4.2.6)	Beta-phosphoglucomutase (EC 5.4.2.6)

CRON 2.
malX	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -86 score = 6.03066 sequence = TTACGAAAACGCTTGCGAAA Site: position = -74 score = 4.9198 sequence = TTGCGAAAGCGTTTGCACAG Gene: lp_0175: Maltose/maltodextrin ABC transporter, substrate-binding protein	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Maltose/maltodextrin ABC transporter, substrate-binding protein
malC	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0176: Maltose/maltodextrin ABC transporter, permease protein 1	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Maltose/maltodextrin ABC transporter, permease protein 1
malD	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0177: Maltose/maltodextrin ABC transporter, permease protein 2	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Maltose/maltodextrin ABC transporter, permease protein 2
malA	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0178: Maltodextrose utilization protein MalA	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Maltodextrose utilization protein MalA

CRON 3.
malR	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367 Gene: LVIS_0356: Maltose utilization transcriptional regulator MalR, LacI family	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0023: Maltose utilization transcriptional regulator MalR, LacI family	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -77 score = 6.2364 sequence = TTATGCAATCGCTTGCAATA Gene: lp_0172: Maltose utilization transcriptional regulator MalR, LacI family	Lactobacillus reuteri JCM 1112 Gene: LAR_0049: Maltose utilization transcriptional regulator MalR, LacI family	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1283: Maltose utilization transcriptional regulator MalR, LacI family	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0891: Maltose utilization transcriptional regulator MalR, LacI family	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0969: Maltose utilization transcriptional regulator MalR, LacI family	Maltose utilization transcriptional regulator MalR, LacI family
mdxR	Lactobacillus acidophilus NCFM Gene: LBA1874: Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334 Gene: LSEI_0979: Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533 Gene: LJ0210: Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family	Lactobacillus plantarum WCFS1 Gene: lp_0173: Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0892: Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Maltose/maltodextrin utilization transcriptional repressor MdxR, LacI family
agl1	Lactobacillus acidophilus NCFM Gene: LBA1872: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus brevis ATCC 367 Gene: LVIS_0309: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus casei ATCC 334 Gene: LSEI_0980: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571 Gene: lhv_2002: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus johnsonii NCC 533 Gene: LJ0211: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus plantarum WCFS1 Gene: lp_0174: Oligo-1,6-glucosidase (EC 3.2.1.10)	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Oligo-1,6-glucosidase (EC 3.2.1.10)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MalR - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --