Statistics of regulated genes

Genome	Genes	Operons
Clostridium kluyveri DSM 555	5	2
Clostridium sp. SS2/1	7	3
Clostridium cellulolyticum H10	5	2
Clostridium phytofermentans ISDg	1	1
Clostridium tetani E88	5	2
Clostridium acetobutylicum ATCC 824	5	2
Clostridium botulinum A str. ATCC 3502	6	3
Clostridium novyi NT	5	2
Clostridium perfringens ATCC 13124	5	2
Clostridium difficile 630	6	3
Clostridium beijerincki NCIMB 8052	5	2
Clostridium sp. OhILAs	1	1
Clostridium sp. L2-50	3	1
Clostridium scindens ATCC 35704	2	2
Clostridium nexile DSM 1787	1	1
Clostridium leptum DSM 753	1	1
Clostridium hiranonis DSM 13275	5	2
Clostridium butyricum 5521	5	2
Clostridium bolteae ATCC BAA-613	1	1
Clostridium bartlettii DSM 16795	6	3

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																					Function
CRON 1.
ribD	* Clostridium kluyveri DSM 555 Site: position = -394 score = 103.11 sequence = AATATGCTTTCGGGG... Gene: CKL_2169: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium sp. SS2/1 Site: position = -336 score = 117.47 sequence = AACGTCTTCAGGGCA... Gene: CLOSS21_03172: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium cellulolyticum H10 Site: position = -206 score = 102.34 sequence = ATGACACTTCAGGGA... Gene: Ccel_2006: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -254 score = 108.51 sequence = ACATCCTTCAGGGTT... Gene: CTC00671: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium acetobutylicum ATCC 824 Site: position = -170 score = 110.37 sequence = ATGTTCTTCAGGGAT... Gene: CAC0590: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium botulinum A str. ATCC 3502 Site: position = -343 score = 106.84 sequence = ATGAATCCTTCAGGG... Gene: CBO2866: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium novyi NT Site: position = -387 score = 113.43 sequence = TTTAATCCTTCAGGG... Gene: NT01CX_0715: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium perfringens ATCC 13124 Site: position = -465 score = 122.32 sequence = AAATTCTTCAGGGCA... Gene: CPF_0546: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium difficile 630 Site: position = -254 score = 118.75 sequence = ACTTAATCTTCGGGG... Gene: CD1700: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium beijerincki NCIMB 8052 Site: position = -447 score = 111.26 sequence = GAAATCTTCGGGGTT... Gene: Cbei_1224: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02834: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	* Clostridium hiranonis DSM 13275 Site: position = -211 score = 123.02 sequence = ACTATCTTCAGGGCA... Gene: CLOHIR_00483: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium butyricum 5521 Site: position = -423 score = 112.25 sequence = TATTAATCTTCAGGG... Gene: CBY_0685: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02805: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Clostridium bartlettii DSM 16795 Site: position = -253 score = 120.74 sequence = GATTATTCTTCGGGG... Gene: CLOBAR_00909: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
ribE	Clostridium kluyveri DSM 555 Gene: CKL_2168: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium sp. SS2/1 Gene: CLOSS21_03173: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium cellulolyticum H10 Gene: Ccel_2005: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00672: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium acetobutylicum ATCC 824 Gene: CAC0591: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium botulinum A str. ATCC 3502 Gene: CBO2865: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium novyi NT Gene: NT01CX_0714: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium perfringens ATCC 13124 Gene: CPF_0547: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium difficile 630 Gene: CD1699: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1225: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium sp. OhILAs	* Clostridium sp. L2-50 Site: position = -457 score = 105.81 sequence = TTGAAGTCTTCAGGG... Gene: CLOL250_02833: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00484: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium butyricum 5521 Gene: CBY_0684: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02806: Riboflavin synthase alpha chain (EC 2.5.1.9)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00908: Riboflavin synthase alpha chain (EC 2.5.1.9)	Riboflavin synthase alpha chain (EC 2.5.1.9)
ribBA	Clostridium kluyveri DSM 555 Gene: CKL_2167: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	*2 Clostridium sp. SS2/1 Site: position = -278 score = 114.87 sequence = AAAATCTTCAGGGCA... Gene: CLOSS21_01003: 3,4-dihydroxy-2-butanone 4-phosphate synthase Gene: CLOSS21_03174: GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium cellulolyticum H10 Gene: Ccel_2004: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00673: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium acetobutylicum ATCC 824 Gene: CAC0592: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium botulinum A str. ATCC 3502 Gene: CBO2864: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium novyi NT Gene: NT01CX_0713: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium perfringens ATCC 13124 Gene: CPF_0548: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium difficile 630 Gene: CD1698: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1226: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02832: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00485: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium butyricum 5521 Gene: CBY_0683: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02807: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00907: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
ribH	Clostridium kluyveri DSM 555 Gene: CKL_2166: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium sp. SS2/1 Gene: CLOSS21_03175: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium cellulolyticum H10 Gene: Ccel_2003: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00674: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium acetobutylicum ATCC 824 Gene: CAC0593: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium botulinum A str. ATCC 3502 Gene: CBO2863: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium novyi NT Gene: NT01CX_0712: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium perfringens ATCC 13124 Gene: CPF_0549: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium difficile 630 Gene: CD1697: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1227: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02831: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00486: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium butyricum 5521 Gene: CBY_0682: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02808: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00906: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
fggY	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_03176: Sugar (pentulose and hexulose) kinase, FGGY family	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_02876: Sugar (pentulose and hexulose) kinase, FGGY family	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -211 score = 121.32 sequence = TATATGTCTTCGGGG... Gene: CLOBAR_00632: Sugar (pentulose and hexulose) kinase, FGGY family	Sugar (pentulose and hexulose) kinase, FGGY family
CRON 2.
ribZ	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium difficile 630 Site: position = -289 score = 97.53 sequence = TTTTTCTTCATAAAC... Gene: CD3299: Riboflavin transporter, COG2814 family	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Riboflavin transporter, COG2814 family
CRON 3.
ribB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -366 score = 111.79 sequence = GTATCCTTCAGGGTT... Gene: CBO2921: 3,4-dihydroxy-2-butanone 4-phosphate synthase	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	3,4-dihydroxy-2-butanone 4-phosphate synthase
CRON 4.
ribU	* Clostridium kluyveri DSM 555 Site: position = -359 score = 122.75 sequence = ATATAATCTTCAGGG... Gene: CKL_3611: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium sp. SS2/1 Site: position = -291 score = 88.7 sequence = TCTCCAACTTCAGGG... Gene: CLOSS21_01295: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium cellulolyticum H10 Site: position = -226 score = 116.22 sequence = AATATCTTCAGGGCA... Gene: Ccel_3408: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium phytofermentans ISDg Site: position = -395 score = 94.18 sequence = AAGTTCTTCGGGGCA... Gene: null: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium tetani E88 Site: position = -211 score = 120.94 sequence = AATATCTTCAGGGCG... Gene: CTC00331: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium acetobutylicum ATCC 824 Site: position = -198 score = 121.47 sequence = GAATGATCTTCAGGG... Gene: CAC2841: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium botulinum A str. ATCC 3502 Site: position = -211 score = 121.04 sequence = AATATCTTCAGGGCG... Gene: CBO0178: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium novyi NT Site: position = -229 score = 124.69 sequence = ATAGTATCTTCAGGG... Gene: NT01CX_0505: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium perfringens ATCC 13124 Site: position = -244 score = 117.16 sequence = AAAAAGTCTTCAGGG... Gene: CPF_2425: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium difficile 630 Site: position = -268 score = 123.2 sequence = AAGATCTTCGGGGCA... Gene: CD0147: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium beijerincki NCIMB 8052 Site: position = -306 score = 121.2 sequence = TATATCTTCAGGGCA... Gene: Cbei_0464: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium sp. OhILAs Site: position = -277 score = 117.93 sequence = TATGATTCTTCAGGG... Gene: Clos_2474: Substrate-specific component RibU of riboflavin ECF transporter	Clostridium sp. L2-50	*2 Clostridium scindens ATCC 35704 Site: position = -142 score = 109.59 sequence = AGAGATTCTTCGGGG... Gene: CLOSCI_02146: Substrate-specific component RibU of riboflavin ECF transporter Site: position = -192 score = 91.41 sequence = GAAGTCTTTGTGGCA... Gene: CLOSCI_02942: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium nexile DSM 1787 Site: position = -239 score = 113.38 sequence = GGATTCTTCGGGGCA... Gene: CLONEX_02849: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium leptum DSM 753 Site: position = -210 score = 119.73 sequence = GCTGTCTTCGGGGCG... Gene: CLOLEP_01531: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium hiranonis DSM 13275 Site: position = -311 score = 112.62 sequence = GATGTCTTCAGGGCA... Gene: CLOHIR_01113: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium butyricum 5521 Site: position = -276 score = 118.91 sequence = TATATCTTCAGGGCA... Gene: CBY_3957: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium bolteae ATCC BAA-613 Site: position = -352 score = 114.43 sequence = TAAAGTTCTTCGGGG... Gene: CLOBOL_02256: Substrate-specific component RibU of riboflavin ECF transporter	* Clostridium bartlettii DSM 16795 Site: position = -231 score = 119.42 sequence = AAAAAATCTTCGGGG... Gene: CLOBAR_00719: Substrate-specific component RibU of riboflavin ECF transporter	Substrate-specific component RibU of riboflavin ECF transporter

Export

	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD