Regulog Rex - Streptococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 161 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By trascription factor - Rex
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Statistics of regulated genes
Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11	6	6
Lactococcus lactis subsp. lactis Il1403	7	7
Streptococcus agalactiae 2603V/R	10	10
Streptococcus dysgalactiae subsp. equisimilis GGS_124	12	10
Streptococcus equi subsp. zooepidemicus MGCS10565	13	11
Streptococcus gallolyticus UCN34	6	6
Streptococcus gordonii str. Challis substr. CH1	9	9
Streptococcus mitis B6	11	9
Streptococcus mutans UA159	12	9
Streptococcus pneumoniae TIGR4	11	9
Streptococcus pyogenes M1 GAS	13	10
Streptococcus sanguinis SK36	11	10
Streptococcus suis 05ZYH33	6	5
Streptococcus thermophilus CNRZ1066	7	6
Streptococcus uberis 0140J	11	10

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
rex	* Lactococcus lactis subsp. cremoris SK11 Site: position = -74 score = 5.26901 sequence = TTGATAAAATTATCACAA Gene: LACR_1156: Redox-sensitive transcriptional regulator Rex, Rex family	* Lactococcus lactis subsp. lactis Il1403 Site: position = -75 score = 5.26901 sequence = TTGATAAAATTATCACAA Gene: L71932: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus agalactiae 2603V/R Site: position = -36 score = 4.46113 sequence = TAATAAAATTTTTAACAA Gene: SAG1100: Redox-sensitive transcriptional regulator Rex, Rex family	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0880: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -31 score = 4.40256 sequence = TAGTTGCATATTTCACAA Gene: Sez_1050: Redox-sensitive transcriptional regulator Rex, Rex family	Streptococcus gallolyticus UCN34 Gene: GALLO_1010: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -54 score = 4.66991 sequence = TAGTTGATTTTTTCACAA Gene: SGO_1228: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus mitis B6 Site: position = -57 score = 5.02144 sequence = TTGTTGATTTTTTCACAA Gene: smi_1188: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus mutans UA159 Site: position = -117 score = 4.38124 sequence = TTGTTATAAAAAAAACTA Site: position = -58 score = 4.47615 sequence = ATGTTGCATTTTTCACAA Gene: SMU.1053: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus pneumoniae TIGR4 Site: position = -57 score = 5.02144 sequence = TTGTTGATTTTTTCACAA Gene: SP_1090: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus pyogenes M1 GAS Site: position = -76 score = 4.47615 sequence = ATGTTGCATTTTTCACAA Gene: SPy1120: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus sanguinis SK36 Site: position = -55 score = 4.66991 sequence = TAGTTGATTTTTTCACAA Gene: SSA_1216: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus suis 05ZYH33 Site: position = -100 score = 4.4648 sequence = CTGTTGATTTTTTCACAA Gene: SSU05_1069: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus thermophilus CNRZ1066 Site: position = -39 score = 4.62402 sequence = TTGTTGCAATCTTCACAA Gene: str1463: Redox-sensitive transcriptional regulator Rex, Rex family	* Streptococcus uberis 0140J Site: position = -52 score = 4.42288 sequence = TTGTTACAATAGTAACAT Gene: SUB0845: Redox-sensitive transcriptional regulator Rex, Rex family	Redox-sensitive transcriptional regulator Rex, Rex family
guaA	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0879: Glutamine amidotransferase	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1051: Glutamine amidotransferase	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_1189: Glutamine amidotransferase	Streptococcus mutans UA159 Gene: SMU.1054: Glutamine amidotransferase	Streptococcus pneumoniae TIGR4 Gene: SP_1089: Glutamine amidotransferase	Streptococcus pyogenes M1 GAS Gene: SPy1119: Glutamine amidotransferase	Streptococcus sanguinis SK36 Gene: SSA_1217: Glutamine amidotransferase	Streptococcus suis 05ZYH33 Gene: SSU05_1070: Glutamine amidotransferase	Streptococcus thermophilus CNRZ1066 Gene: str1464: Glutamine amidotransferase	Streptococcus uberis 0140J Gene: SUB0844: Glutamine amidotransferase	Glutamine amidotransferase

CRON 2.
fba	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_2168: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -63 score = 4.77811 sequence = TAGAAAAATACTTCACAA Gene: L0009: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Streptococcus agalactiae 2603V/R Gene: SAG0127: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0336: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1717: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus gallolyticus UCN34 Site: position = -60 score = 4.22551 sequence = TTGTGATAAAATGTACGT Gene: GALLO_0255: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -61 score = 4.60711 sequence = AAGTGATAAAATAAACAA Gene: SGO_1745: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus mitis B6 Site: position = -62 score = 4.51581 sequence = AAGTGATAAAATGAACAA Gene: smi_0695: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus mutans UA159 Site: position = -61 score = 4.60711 sequence = AAGTGATAAAATAAACAA Gene: SMU.99: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus pneumoniae TIGR4 Site: position = -62 score = 4.51581 sequence = AAGTGATAAAATGAACAA Gene: SP_0605: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Streptococcus pyogenes M1 GAS Gene: SPy1889: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus sanguinis SK36 Site: position = -62 score = 4.60711 sequence = AAGTGATAAAATAAACAA Gene: SSA_1992: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus suis 05ZYH33 Site: position = -111 score = 4.66534 sequence = ATGTGAAAGTTTTCTCAA Gene: SSU05_0336: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus thermophilus CNRZ1066 Site: position = -60 score = 4.92415 sequence = TTGTGATAAAATAAACAT Gene: str1899: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	* Streptococcus uberis 0140J Site: position = -59 score = 4.42993 sequence = TTGTGCTAAAATGAACAA Gene: SUB0330: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)	Fructose-bisphosphate aldolase class II (EC 4.1.2.13)

CRON 3.
eno	* Lactococcus lactis subsp. cremoris SK11 Site: position = -80 score = 4.43331 sequence = TTGAAAAATCTTTCAAAA Gene: LACR_0668: Enolase (EC 4.2.1.11)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -80 score = 4.43331 sequence = TTGAAAAATCTTTCAAAA Gene: L0007: Enolase (EC 4.2.1.11)	* Streptococcus agalactiae 2603V/R Site: position = -123 score = 4.35087 sequence = TAGTGATTTTTTTATCAA Gene: SAG0628: Enolase (EC 4.2.1.11)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -52 score = 4.79417 sequence = TTGTGGTATTATTAACAT Gene: SDEG_0704: Enolase (EC 4.2.1.11)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -52 score = 4.79417 sequence = TTGTGGTATTATTAACAT Gene: Sez_0774: Enolase (EC 4.2.1.11)	* Streptococcus gallolyticus UCN34 Site: position = -38 score = 4.4108 sequence = GTGTAAAAATATTAAAAA Gene: GALLO_1458: Enolase (EC 4.2.1.11)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1426: Enolase (EC 4.2.1.11)	Streptococcus mitis B6 Gene: smi_1159: Enolase (EC 4.2.1.11)	* Streptococcus mutans UA159 Site: position = -49 score = 4.55535 sequence = TTGTGGTATGATTAACAT Gene: SMU.1247: Enolase (EC 4.2.1.11)	Streptococcus pneumoniae TIGR4 Gene: SP_1128: Enolase (EC 4.2.1.11)	* Streptococcus pyogenes M1 GAS Site: position = -52 score = 4.33191 sequence = TTGTGGTATTATGAACAT Gene: SPy0731: Enolase (EC 4.2.1.11)	* Streptococcus sanguinis SK36 Site: position = -111 score = 4.68657 sequence = TTGTGCAAAATTTCTCAA Site: position = -35 score = 4.15779 sequence = TAGTAAATAATTTTAAAT Gene: SSA_0886: Enolase (EC 4.2.1.11)	Streptococcus suis 05ZYH33 Gene: SSU05_1503: Enolase (EC 4.2.1.11)	Streptococcus thermophilus CNRZ1066 Gene: str0635: Enolase (EC 4.2.1.11)	* Streptococcus uberis 0140J Site: position = -101 score = 4.29731 sequence = AAGTGAAATTTTTCATTA Site: position = -52 score = 4.21914 sequence = TTGTGATATTATGGACAT Gene: SUB0655: Enolase (EC 4.2.1.11)	Enolase (EC 4.2.1.11)

CRON 4.
pgk	* Lactococcus lactis subsp. cremoris SK11 Site: position = -91 score = 4.52865 sequence = TTGTGATATAATTAACCT Gene: LACR_0248: Phosphoglycerate kinase (EC 2.7.2.3)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -91 score = 4.52865 sequence = TTGTGATATAATTAACCT Gene: L0010: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus agalactiae 2603V/R Site: position = -84 score = 4.6767 sequence = TTGTGAAAAAGTAATCAA Gene: SAG1766: Phosphoglycerate kinase (EC 2.7.2.3)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_1934: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -96 score = 4.33359 sequence = TTGTGAAATAGTTAATTT Gene: Sez_0272: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus gallolyticus UCN34 Site: position = -137 score = 4.36103 sequence = TTGTAAAATGATACAGAA Site: position = -47 score = 4.53122 sequence = TTGTGATATAATTAGCAT Gene: GALLO_1995: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -46 score = 4.69382 sequence = TTGTGATATAATTATCAT Gene: SGO_0209: Phosphoglycerate kinase (EC 2.7.2.3)	Streptococcus mitis B6 Gene: smi_0346: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus mutans UA159 Site: position = -47 score = 4.69382 sequence = TTGTGATATAATTATCAT Gene: SMU.361: Phosphoglycerate kinase (EC 2.7.2.3)	Streptococcus pneumoniae TIGR4 Gene: SP_0499: Phosphoglycerate kinase (EC 2.7.2.3)	Streptococcus pyogenes M1 GAS Gene: SPy1881: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus sanguinis SK36 Site: position = -87 score = 4.45931 sequence = TTGTGAAAATTTTCTTTA Gene: SSA_0302: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus suis 05ZYH33 Site: position = -87 score = 4.3831 sequence = TTGTGAAAAAAATATCTT Gene: SSU05_0157: Phosphoglycerate kinase (EC 2.7.2.3)	Streptococcus thermophilus CNRZ1066 Gene: str1782: Phosphoglycerate kinase (EC 2.7.2.3)	* Streptococcus uberis 0140J Site: position = -96 score = 4.50276 sequence = TTGTGAAAAAAATAATTT Gene: SUB1629: Phosphoglycerate kinase (EC 2.7.2.3)	Phosphoglycerate kinase (EC 2.7.2.3)

CRON 5.
adhB1	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1990: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Lactococcus lactis subsp. lactis Il1403 Gene: L55758: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus agalactiae 2603V/R Site: position = -118 score = 4.37157 sequence = TTAAGAATATTTTCAAAA Site: position = -73 score = 4.75392 sequence = TTGTGAAGAATAATACAA Gene: SAG0054: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -76 score = 5.08913 sequence = TTGTGAAAAGATATACAA Gene: SDEG_0062: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -80 score = 5.10393 sequence = TTGTGAAAAAGTATACAA Gene: Sez_0046: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus gallolyticus UCN34	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -52 score = 5.20982 sequence = TTGTGATATAATTAACAT Gene: SGO_0565: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus mitis B6 Site: position = -114 score = 5.08796 sequence = TTGTGATATACTTCACAT Gene: smi_0275: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus mutans UA159	* Streptococcus pneumoniae TIGR4 Site: position = -114 score = 5.08796 sequence = TTGTGATATACTTCACAT Gene: SP_0285: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus pyogenes M1 GAS Site: position = -67 score = 4.99783 sequence = TTGTGAAAAGATGTACAA Gene: SPy0044: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus sanguinis SK36 Site: position = -51 score = 5.20982 sequence = TTGTGATATAATTAACAT Gene: SSA_1917: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Streptococcus suis 05ZYH33 Site: position = -82 score = 5.22965 sequence = TTGTGATATTCTTAACAA Gene: SSU05_0279: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	3 Streptococcus thermophilus CNRZ1066 Gene: str0882: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent Gene: str0881: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent Gene: str0880: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus uberis 0140J	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

CRON 6.
gap	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -76 score = 4.40763 sequence = AAGTTAATCTTTTCACAT Gene: SAG1768: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -78 score = 4.68331 sequence = AAGTTAATCTTTTCACAA Gene: SDEG_1936: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -158 score = 4.00804 sequence = ATTTGAAAGAATGAACAA Gene: SGO_0207: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Streptococcus mitis B6 Gene: smi_0232: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus mutans UA159 Site: position = -81 score = 4.68331 sequence = AAGTTAATCTTTTCACAA Gene: SMU.360: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Streptococcus pneumoniae TIGR4 Gene: SP_2012: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus pyogenes M1 GAS Site: position = -79 score = 4.68331 sequence = AAGTTAATCTTTTCACAA Gene: SPy0274: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus sanguinis SK36 Site: position = -157 score = 4.75191 sequence = TAGTGAAAGAATTCATAA Gene: SSA_2108: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	Streptococcus suis 05ZYH33 Gene: SSU05_0155: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus thermophilus CNRZ1066 Site: position = -50 score = 4.68331 sequence = AAGTTAATCTTTTCACAA Gene: str1788: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	* Streptococcus uberis 0140J Site: position = -78 score = 4.68331 sequence = AAGTTAATCTTTTCACAA Gene: SUB1630: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)	NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)

CRON 7.
noxE	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_0437: NADH oxidase (EC 1.6.99.3)	Lactococcus lactis subsp. lactis Il1403 Gene: L196579: NADH oxidase (EC 1.6.99.3)	* Streptococcus agalactiae 2603V/R Site: position = -165 score = 4.32726 sequence = TTGTGAATTTGTGAAAAA Site: position = -59 score = 4.68278 sequence = TTGTGAATAATGTTATAA Gene: SAG0958: NADH oxidase (EC 1.6.99.3)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -23 score = 4.5751 sequence = TTGTGAAATGAGGAACAA Gene: SDEG_0909: NADH oxidase (EC 1.6.99.3)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -81 score = 4.29942 sequence = TTGTGAAATGAGGAACAT Gene: Sez_1023: NADH oxidase (EC 1.6.99.3)	Streptococcus gallolyticus UCN34 Gene: GALLO_1130: NADH oxidase (EC 1.6.99.3)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1167: NADH oxidase (EC 1.6.99.3)	Streptococcus mitis B6 Gene: smi_1390: NADH oxidase (EC 1.6.99.3)	Streptococcus mutans UA159 Gene: SMU.1117: NADH oxidase (EC 1.6.99.3)	Streptococcus pneumoniae TIGR4 Gene: SP_1469: NADH oxidase (EC 1.6.99.3)	* Streptococcus pyogenes M1 GAS Site: position = -23 score = 4.5751 sequence = TTGTGAAATGAGGAACAA Gene: SPy1150: NADH oxidase (EC 1.6.99.3)	Streptococcus sanguinis SK36 Gene: SSA_1127: NADH oxidase (EC 1.6.99.3)	Streptococcus suis 05ZYH33 Gene: SSU05_0730: NADH oxidase (EC 1.6.99.3)	* Streptococcus thermophilus CNRZ1066 Site: position = -91 score = 4.55068 sequence = TTGTTCAAAAAGTAACAA Gene: str1281: NADH oxidase (EC 1.6.99.3)	* Streptococcus uberis 0140J Site: position = -170 score = 4.57752 sequence = TTGTGAATTTATGAACTA Site: position = -24 score = 4.66039 sequence = TTGTGAAAAGAGGAACAA Gene: SUB0877: NADH oxidase (EC 1.6.99.3)	NADH oxidase (EC 1.6.99.3)

CRON 8.
tpi	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1244: Triosephosphate isomerase (EC 5.3.1.1)	Lactococcus lactis subsp. lactis Il1403 Gene: L0006: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus agalactiae 2603V/R Site: position = -72 score = 3.99514 sequence = TCGTGAAACTTTTAATTA Gene: SAG0763: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -97 score = 5.05448 sequence = TTGTGAAAATATTCCTAA Gene: SDEG_0629: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -97 score = 4.95725 sequence = TTGTGAAAATATTACTAA Gene: Sez_1321: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus gallolyticus UCN34 Gene: GALLO_1510: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -89 score = 4.52822 sequence = TTGATAAAAACTTAGCAA Gene: SGO_0762: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus mitis B6 Gene: smi_1564: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus mutans UA159 Gene: SMU.715: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus pneumoniae TIGR4 Gene: SP_1574: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus pyogenes M1 GAS Site: position = -97 score = 5.05448 sequence = TTGTGAAAATATTCCTAA Gene: SPy0613: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus sanguinis SK36 Gene: SSA_0859: Triosephosphate isomerase (EC 5.3.1.1)	Streptococcus suis 05ZYH33 Gene: SSU05_0531: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus thermophilus CNRZ1066 Site: position = -46 score = 4.68126 sequence = TTGTGATAAAATAAACGA Gene: str0488: Triosephosphate isomerase (EC 5.3.1.1)	* Streptococcus uberis 0140J Site: position = -98 score = 5.23344 sequence = TTGTGAAAATTATCCCAA Gene: SUB0605: Triosephosphate isomerase (EC 5.3.1.1)	Triosephosphate isomerase (EC 5.3.1.1)

CRON 9.
nirC	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1054: Formate/nitrite family of transporters	Lactococcus lactis subsp. lactis Il1403 Gene: L195318: Formate/nitrite family of transporters	* Streptococcus agalactiae 2603V/R Site: position = -32 score = 4.51759 sequence = AAGTTAATAAAATCACAT Gene: SAG1084: Formate/nitrite family of transporters	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -2 score = 4.78424 sequence = TTGTGAATACGATAACAA Gene: SDEG_1466: Formate/nitrite family of transporters	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -2 score = 5.06311 sequence = TTGTGAATATACTAACAA Gene: Sez_0639: Formate/nitrite family of transporters	Streptococcus gallolyticus UCN34	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -40 score = 3.82296 sequence = ATGATATATTGGTCATAA Gene: SGO_1137: Formate/nitrite family of transporters	* Streptococcus mitis B6 Site: position = -41 score = 4.30435 sequence = TTGTGATATAATTATCAG Gene: smi_1009: Formate/nitrite family of transporters	Streptococcus mutans UA159 Gene: SMU.89c: Formate/nitrite family of transporters	* Streptococcus pneumoniae TIGR4 Site: position = -41 score = 4.9695 sequence = TTGTGATATAATTATCAA Gene: SP_1215: Formate/nitrite family of transporters	* Streptococcus pyogenes M1 GAS Site: position = -29 score = 4.79569 sequence = TTGTGAATACAGTAACAA Gene: SPy1424: Formate/nitrite family of transporters	* Streptococcus sanguinis SK36 Site: position = -44 score = 4.53101 sequence = TTGTGATATACTATACAT Gene: SSA_1098: Formate/nitrite family of transporters	Streptococcus suis 05ZYH33 Gene: SSU05_0269: Formate/nitrite family of transporters	Streptococcus thermophilus CNRZ1066 Gene: str1830: Formate/nitrite family of transporters	* Streptococcus uberis 0140J Site: position = -29 score = 4.87725 sequence = TTGTGAAAATGATAACTA Gene: SUB1260: Formate/nitrite family of transporters	Formate/nitrite family of transporters

CRON 10.
pncB	* Lactococcus lactis subsp. cremoris SK11 Site: position = -218 score = 4.02503 sequence = TTGTAGTATAAAAAACAT Gene: LACR_1202: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -181 score = 3.90072 sequence = TTGTAGTACAAAAAACAT Gene: L107468: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus agalactiae 2603V/R Gene: SAG0295: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -39 score = 4.69769 sequence = ATGTTATAATAGTAACAA Gene: SDEG_1714: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -39 score = 4.29047 sequence = ATGGTATAATAATAACAA Gene: Sez_1574: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus gallolyticus UCN34 Gene: GALLO_0476: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0582: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus mitis B6 Site: position = -114 score = 4.26608 sequence = TTGTTACTCTTTTCTCAA Gene: smi_1492: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus mutans UA159 Site: position = -265 score = 4.28233 sequence = GTGTTATAATAGTAACAA Gene: SMU.464: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus pneumoniae TIGR4 Site: position = -114 score = 4.26608 sequence = TTGTTACTCTTTTCTCAA Gene: SP_1421: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	* Streptococcus pyogenes M1 GAS Site: position = -39 score = 4.69769 sequence = ATGTTATAATAGTAACAA Gene: SPy1653: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus sanguinis SK36 Gene: SSA_1864: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus suis 05ZYH33 Gene: SSU05_1672: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus thermophilus CNRZ1066 Gene: str0226: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Streptococcus uberis 0140J Gene: SUB1410: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
nadE	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1204: NAD synthetase (EC 6.3.1.5)	Lactococcus lactis subsp. lactis Il1403 Gene: L0203: NAD synthetase (EC 6.3.1.5)	Streptococcus agalactiae 2603V/R Gene: SAG0296: NAD synthetase (EC 6.3.1.5)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_1713: NAD synthetase (EC 6.3.1.5)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1573: NAD synthetase (EC 6.3.1.5)	Streptococcus gallolyticus UCN34 Gene: GALLO_0477: NAD synthetase (EC 6.3.1.5)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0583: NAD synthetase (EC 6.3.1.5)	Streptococcus mitis B6 Gene: smi_1491: NAD synthetase (EC 6.3.1.5)	Streptococcus mutans UA159 Gene: SMU.465: NAD synthetase (EC 6.3.1.5)	Streptococcus pneumoniae TIGR4 Gene: SP_1420: NAD synthetase (EC 6.3.1.5)	Streptococcus pyogenes M1 GAS Gene: SPy1652: NAD synthetase (EC 6.3.1.5)	Streptococcus sanguinis SK36 Gene: SSA_1863: NAD synthetase (EC 6.3.1.5)	Streptococcus suis 05ZYH33 Gene: SSU05_1673: NAD synthetase (EC 6.3.1.5)	Streptococcus thermophilus CNRZ1066 Gene: str0227: NAD synthetase (EC 6.3.1.5)	Streptococcus uberis 0140J Gene: SUB1409: NAD synthetase (EC 6.3.1.5)	NAD synthetase (EC 6.3.1.5)

CRON 11.
ahpC	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_0383: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Lactococcus lactis subsp. lactis Il1403 Gene: L135351: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Streptococcus agalactiae 2603V/R Gene: SAG1833: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -141 score = 4.51139 sequence = ATGTGATGCTATTCACAT Gene: SDEG_2053: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -134 score = 4.96218 sequence = TTGTGACTAAATTCACAT Gene: Sez_0137: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Streptococcus gallolyticus UCN34 Gene: GALLO_1918: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.764: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Streptococcus pneumoniae TIGR4	* Streptococcus pyogenes M1 GAS Site: position = -136 score = 5.11121 sequence = ATGTGATTTATTTCACAA Gene: SPy2079: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1752: Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)	Alkyl hydroperoxide reductase protein C (EC 1.11.1.15)
ahpF	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_0384: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Lactococcus lactis subsp. lactis Il1403 Gene: L135954: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus agalactiae 2603V/R Gene: SAG1834: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2054: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34 Gene: GALLO_1917: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.765: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS Gene: SPy2080: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1753: Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)	Alkyl hydroperoxide reductase protein F (EC 1.11.1.15)

CRON 12.
ldh	* Lactococcus lactis subsp. cremoris SK11 Site: position = -63 score = 4.07815 sequence = TTGTTGAAAAGATTATAT Gene: LACR_1455: L-lactate dehydrogenase (EC 1.1.1.27)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -63 score = 4.07815 sequence = TTGTTGAAAAGATTATAT Gene: L0017: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus agalactiae 2603V/R Site: position = -102 score = 4.37899 sequence = TTGCAAATTTTTTCACAT Gene: SAG0959: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -77 score = 4.20819 sequence = ATGACAAACAATTCTCAA Gene: SDEG_0911: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -79 score = 3.92992 sequence = ATGACAAAGACATTACAA Gene: Sez_1022: L-lactate dehydrogenase (EC 1.1.1.27)	2 Streptococcus gallolyticus UCN34* Site: position = -85 score = 3.80197 sequence = TTATTATACAATTCCAAA Gene: GALLO_2034: L-lactate dehydrogenase (EC 1.1.1.27) Site: position = -106 score = 4.02834 sequence = TTTTCAAAGTTTTTACAA Gene: GALLO_1129: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -118 score = 3.83739 sequence = TTCTAAAAACGTTTACAT Gene: SGO_1232: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus mitis B6 Site: position = -62 score = 4.24013 sequence = AAGTGATAAAATTAAAAT Gene: smi_1006: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus mutans UA159 Site: position = -81 score = 4.44796 sequence = TAGTGACTTTCTTAACAA Gene: SMU.1115: L-lactate dehydrogenase (EC 1.1.1.27)	Streptococcus pneumoniae TIGR4 Gene: SP_1220: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus pyogenes M1 GAS Site: position = -77 score = 4.11095 sequence = ATGACAAACAATTATCAA Gene: SPy1151: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus sanguinis SK36 Site: position = -116 score = 4.52845 sequence = TTGTAAAAACGTTTACAT Gene: SSA_1221: L-lactate dehydrogenase (EC 1.1.1.27)	Streptococcus suis 05ZYH33 Gene: SSU05_1076: L-lactate dehydrogenase (EC 1.1.1.27)	Streptococcus thermophilus CNRZ1066 Gene: str1280: L-lactate dehydrogenase (EC 1.1.1.27)	* Streptococcus uberis 0140J Site: position = -77 score = 4.27207 sequence = GTGACAAACTATTCACAA Gene: SUB0879: L-lactate dehydrogenase (EC 1.1.1.27)	L-lactate dehydrogenase (EC 1.1.1.27)

CRON 13.
gapN	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG0823: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_1419: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0766: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus gallolyticus UCN34 Gene: GALLO_0746: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.676: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	* Streptococcus pneumoniae TIGR4 Site: position = -94 score = 5.19202 sequence = TTGTGAAAATAATCTCAA Gene: SP_1119: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus pyogenes M1 GAS Gene: SPy1371: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	* Streptococcus sanguinis SK36 Site: position = -91 score = 4.53656 sequence = TTGTGAAAAAATTCTTTA Gene: SSA_0774: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066 Gene: str1263: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Streptococcus uberis 0140J Gene: SUB1220: Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)	Glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

CRON 14.
hemH	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1661: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Lactococcus lactis subsp. lactis Il1403 Gene: L0194: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1311: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	* Streptococcus mitis B6 Site: position = -28 score = 5.12717 sequence = TTGATAAAAACATCACAA Gene: smi_1138: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Streptococcus mutans UA159 Gene: SMU.2063: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	* Streptococcus pneumoniae TIGR4 Site: position = -28 score = 5.12717 sequence = TTGATAAAAACATCACAA Gene: SP_1009: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_1321: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Streptococcus suis 05ZYH33	3 Streptococcus thermophilus CNRZ1066 Gene: str0933: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) Gene: str0935: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1) Gene: str0934: Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)	Streptococcus uberis 0140J	Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1)

CRON 15.
adhE	* Lactococcus lactis subsp. cremoris SK11 Site: position = -101 score = 4.95574 sequence = TTGTAAATTTCATCACAA Site: position = -58 score = 4.71212 sequence = TTGTTAAACTATTCACGT Site: position = -34 score = 4.54033 sequence = AAGTGAATGAAATCACAA Gene: LACR_2457: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Lactococcus lactis subsp. lactis Il1403 Site: position = -34 score = 4.29101 sequence = AAGTGAATGAAGTCACAA Site: position = -101 score = 5.03354 sequence = TTGTAAAAACTATCACAA Site: position = -58 score = 4.71212 sequence = TTGTTAAACTATTCACGT Gene: L13145: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus agalactiae 2603V/R Site: position = -35 score = 5.57434 sequence = TTGTGAAACATTTAACAA Site: position = -113 score = 5.17325 sequence = TTGAAAAAAAGTTCACAA Site: position = -90 score = 5.48931 sequence = TTGTGAAACTATTTACAA Gene: SAG0053: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -112 score = 5.21493 sequence = TTGAAAAAAACTTCACAA Site: position = -89 score = 5.3748 sequence = TTGTGAAATGATTTACAA Site: position = -34 score = 5.53758 sequence = TTGTGAAACTTTTAACAA Gene: SDEG_0061: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -112 score = 5.03805 sequence = TTGAAAAAAACATCACAA Site: position = -89 score = 5.3748 sequence = TTGTGAAATGATTTACAA Site: position = -34 score = 5.53758 sequence = TTGTGAAACTTTTAACAA Gene: Sez_0043: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus gallolyticus UCN34 Site: position = -260 score = 4.18191 sequence = TTGTAATAAAAATGAAAA Site: position = -216 score = 4.3487 sequence = TTGAAAAAAGTTTAATAT Site: position = -195 score = 4.73743 sequence = TGGTGAAGAATATCACAA Gene: GALLO_0220: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -140 score = 5.0546 sequence = TTGAAATATATTTCACAA Site: position = -51 score = 5.82442 sequence = TTGTGAAAAAATTAACAA Gene: SGO_0113: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus mitis B6 Site: position = -191 score = 5.10313 sequence = TTGAAATAATTTTCACAA Site: position = -209 score = 4.51929 sequence = TTGTGAAATAAAAAATAT Site: position = -141 score = 5.41041 sequence = ATGAGAAAAATTTCACAA Site: position = -97 score = 4.63737 sequence = TTATGAAACTGTTTACAA Site: position = -53 score = 5.82442 sequence = TTGTGAAAAAATTAACAA Gene: smi_0231: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus mutans UA159 Site: position = -130 score = 5.26511 sequence = TTGGGAAAAAATTCACAA Site: position = -96 score = 4.7731 sequence = TTGTGAAAAGGGTTACAA Site: position = -74 score = 4.75865 sequence = AAGTGAAGAAAATCACAA Gene: SMU.148: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus pneumoniae TIGR4 Site: position = -208 score = 4.51929 sequence = TTGTGAAATAAAAAATAT Site: position = -190 score = 5.13989 sequence = TTGAAATAAATTTCACAA Site: position = -140 score = 5.13483 sequence = ATGAGAAAAGTTTCACAA Site: position = -96 score = 4.63737 sequence = TTATGAAACTGTTTACAA Site: position = -52 score = 5.82442 sequence = TTGTGAAAAAATTAACAA Gene: SP_2026: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Streptococcus pyogenes M1 GAS	* Streptococcus sanguinis SK36 Site: position = -156 score = 4.97989 sequence = TTGTTATGTATTTCACAA Site: position = -67 score = 5.69865 sequence = TTGTGAAATATTTAACAA Site: position = -226 score = 4.30684 sequence = ATGTGAAATCTTTAAAAT Gene: SSA_0068: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus suis 05ZYH33 Site: position = -129 score = 4.52821 sequence = TTGGGGAAAAGTTAACAA Gene: SSU05_0280: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus thermophilus CNRZ1066 Site: position = -37 score = 5.26848 sequence = TTGTGAAGTTTTTAACAA Gene: str1884: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Streptococcus uberis 0140J Site: position = -38 score = 5.53758 sequence = TTGTGAAACTTTTAACAA Site: position = -116 score = 5.17325 sequence = TTGAAAAAAAGTTCACAA Site: position = -93 score = 5.48931 sequence = TTGTGAAACTATTTACAA Gene: SUB0063: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)

CRON 16.
adhB2	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1637: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0045: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	* Streptococcus mitis B6 Site: position = -95 score = 4.98311 sequence = AAGTTAAAAAAATCACAA Gene: smi_0203: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus mutans UA159	* Streptococcus pneumoniae TIGR4 Site: position = -96 score = 4.98311 sequence = AAGTTAAAAAAATCACAA Gene: SP_2055: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus pyogenes M1 GAS Gene: SPy1111: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

CRON 17.
frdC	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34 Gene: GALLO_0892: Fumarate reductase	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	* Streptococcus mutans UA159 Site: position = -57 score = 4.12244 sequence = ATGTGATGTTTTTCACTT Gene: SMU.1410: Fumarate reductase	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Fumarate reductase
frdT	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34 Gene: GALLO_0891: Predicted fumarate permease	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.1411: Predicted fumarate permease	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Predicted fumarate permease

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Rex - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --