Regulog IscR - Desulfuromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	Rrf2
Regulation mode:	activator (repressor)
Biological process:	Iron-sulfur cluster biogenesis
Effector:	Iron-sulfur cluster redox state
Phylum:	Proteobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 8 sites [see more]

Member of regulog collections

By taxonomy - Desulfuromonadales
By trascription factor - IscR
By TF family - Rrf2
By effector - Iron-sulfur cluster redox state
By pathway - Iron-sulfur cluster biogenesis

Statistics of regulated genes
Genome	Genes	Operons
Geobacter metallireducens GS-15	5	2
Geobacter sulfurreducens PCA	5	2
Geobacter uraniumreducens Rf4	3	1
Geobacter sp. FRC-32	3	1
Geobacter sp. M21
Geobacter lovleyi SZ
Pelobacter propionicus DSM 2379
Pelobacter carbinolicus str. DSM 2380	3	1
Desulfuromonas acetoxidans DSM 684	3	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
iscU	* Geobacter metallireducens GS-15 Site: position = -62 score = 6.42768 sequence = ATACCTGACAATTTTGCTATAGTAT Gene: Gmet_0991: Iron-sulfur cluster assembly scaffold protein IscU	* Geobacter sulfurreducens PCA Site: position = -59 score = 6.42768 sequence = ATACCTGACAATTTTGCTATAGTAT Gene: GSU2012: Iron-sulfur cluster assembly scaffold protein IscU	Geobacter uraniumreducens Rf4 Gene: Gura_1832: Iron-sulfur cluster assembly scaffold protein IscU	Geobacter sp. FRC-32 Gene: Geob_3050: Iron-sulfur cluster assembly scaffold protein IscU	Geobacter sp. M21 Gene: GM21_2648: Iron-sulfur cluster assembly scaffold protein IscU	Geobacter lovleyi SZ Gene: Glov_1606: Iron-sulfur cluster assembly scaffold protein IscU	Pelobacter propionicus DSM 2379 Gene: Ppro_2016: Iron-sulfur cluster assembly scaffold protein IscU	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0051: Iron-sulfur cluster assembly scaffold protein IscU	Desulfuromonas acetoxidans DSM 684	Iron-sulfur cluster assembly scaffold protein IscU
iscS2	Geobacter metallireducens GS-15 Gene: Gmet_0992: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sulfurreducens PCA Gene: GSU2011: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter uraniumreducens Rf4 Gene: Gura_1833: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sp. FRC-32 Gene: Geob_3049: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sp. M21 Gene: GM21_2647: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter lovleyi SZ Gene: Glov_1607: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Pelobacter propionicus DSM 2379 Gene: Ppro_2015: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_0050: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Desulfuromonas acetoxidans DSM 684	Cysteine desulfurase (EC 2.8.1.7), IscS subfamily

CRON 2.
cysE	* Geobacter metallireducens GS-15 Site: position = -138 score = 7.09797 sequence = ATAGTTGACAGATTTTGTAAGGTAT Gene: Gmet_0870: Serine acetyltransferase (EC 2.3.1.30)	* Geobacter sulfurreducens PCA Site: position = -130 score = 6.45956 sequence = GAAGTTGACAAAAATTGTAGGGTAT Gene: GSU2572: Serine acetyltransferase (EC 2.3.1.30)	* Geobacter uraniumreducens Rf4 Site: position = -75 score = 7.05837 sequence = ATAATTGACTAAAATAGTAAGGTAT Gene: Gura_1495: Serine acetyltransferase (EC 2.3.1.30)	* Geobacter sp. FRC-32 Site: position = -69 score = 6.97942 sequence = ATAATTGACTGAAATAGTAAGGTAT Gene: Geob_1982: Serine acetyltransferase (EC 2.3.1.30)	Geobacter sp. M21	Geobacter lovleyi SZ Gene: Glov_2614: Serine acetyltransferase (EC 2.3.1.30)	Pelobacter propionicus DSM 2379 Gene: Ppro_0748: Serine acetyltransferase (EC 2.3.1.30)	* Pelobacter carbinolicus str. DSM 2380 Site: position = -76 score = 6.45956 sequence = ATAGTTGACAAAAATGATCAGGCAT Gene: Pcar_1862: Serine acetyltransferase (EC 2.3.1.30)	* Desulfuromonas acetoxidans DSM 684 Site: position = -47 score = 6.01781 sequence = ATAGTTGACAGTTATGCTCAGGAAT Gene: Dace_1031: Serine acetyltransferase (EC 2.3.1.30)	Serine acetyltransferase (EC 2.3.1.30)
iscR	Geobacter metallireducens GS-15 Gene: Gmet_0871: Iron-sulfur cluster regulator IscR	Geobacter sulfurreducens PCA Gene: GSU2571: Iron-sulfur cluster regulator IscR	Geobacter uraniumreducens Rf4 Gene: Gura_1494: Iron-sulfur cluster regulator IscR	Geobacter sp. FRC-32 Gene: Geob_1981: Iron-sulfur cluster regulator IscR	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1861: Iron-sulfur cluster regulator IscR	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1030: Iron-sulfur cluster regulator IscR	Iron-sulfur cluster regulator IscR
iscS	Geobacter metallireducens GS-15 Gene: Gmet_0872: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sulfurreducens PCA Gene: GSU2570: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter uraniumreducens Rf4 Gene: Gura_1493: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sp. FRC-32 Gene: Geob_1980: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1860: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Desulfuromonas acetoxidans DSM 684 Gene: Dace_1029: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Cysteine desulfurase (EC 2.8.1.7), IscS subfamily

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog IscR - Desulfuromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --