Regulog NrdR - Pasteurellales

Properties
Regulator type:	Transcription factor
Regulator family:	NrdR
Regulation mode:	repressor
Biological process:	Deoxyribonucleotide biosynthesis
Effector:	Deoxyribonucleotides
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 41 sites [see more]

Member of regulog collections

By trascription factor - NrdR
By taxonomy - Pasteurellales
By TF family - NrdR
By effector - Deoxyribonucleotides
By pathway - Deoxyribonucleotide biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Haemophilus influenzae Rd KW20	3	2
Aggregatibacter aphrophilus NJ8700	2	2
Pasteurella multocida subsp. multocida str. Pm70	3	2
Mannheimia succiniciproducens MBEL55E	3	2
Actinobacillus succinogenes 130Z	4	2
Haemophilus somnus 2336	3	2
Actinobacillus pleuropneumoniae serovar 7 str. AP76	6	3
Haemophilus ducreyi 35000HP	4	2
Haemophilus parasuis SH0165	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
nrdA	* Haemophilus influenzae Rd KW20 Site: position = -56 score = 5.62711 sequence = ACACTATATCTTGTGT Site: position = -87 score = 5.1182 sequence = ACACATTATCTTGTGG Gene: HI1659: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Aggregatibacter aphrophilus NJ8700 Site: position = -50 score = 4.95587 sequence = CAACTATATGTTGTGT Site: position = -81 score = 4.84439 sequence = ACACATTATCTTGTGC Gene: NT05HA_0693: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -44 score = 5.62711 sequence = ACACAATATCTTGTGT Site: position = -75 score = 4.64632 sequence = GCACATTATCTTGTAT Gene: PM0717: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Mannheimia succiniciproducens MBEL55E Site: position = -41 score = 4.51764 sequence = ACCCACTATCTTGTAG Site: position = -10 score = 4.88572 sequence = CTTCTATATATTGTGT Gene: MS0992: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Actinobacillus succinogenes 130Z Site: position = -33 score = 5.24402 sequence = AATCTATATATTGTGT Site: position = -64 score = 4.51764 sequence = ACCCACTATCTTGTAG Gene: Asuc_1466: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Haemophilus somnus 2336 Site: position = -47 score = 5.25623 sequence = TAACTATATCTTGTGT Site: position = -78 score = 5.01245 sequence = ACACATTATCTTGTAG Gene: HSM_0366: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -78 score = 5.36189 sequence = AAACAATATCTTGTAT Site: position = -47 score = 5.01447 sequence = CCACAAGATATAGTGG Gene: APP7_1045: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Haemophilus ducreyi 35000HP Site: position = -78 score = 4.55177 sequence = AAACCATATCTTGTAC Site: position = -47 score = 5.10215 sequence = CCACAACATATAGTGG Gene: HD1731: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Haemophilus parasuis SH0165	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB	Haemophilus influenzae Rd KW20 Gene: HI1660: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0691: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0719: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Mannheimia succiniciproducens MBEL55E Gene: MS0968: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Actinobacillus succinogenes 130Z Gene: Asuc_1480: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Haemophilus somnus 2336 Gene: HSM_1436: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_1046: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Haemophilus ducreyi 35000HP Gene: HD1732: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Haemophilus parasuis SH0165	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)

CRON 2.
nrdB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0828: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -149 score = 4.32025 sequence = ACACTAGATATGGGTT Site: position = -180 score = 5.15901 sequence = ATACAATATCTAGTAT Gene: APP7_0149: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Haemophilus ducreyi 35000HP	* Haemophilus parasuis SH0165 Site: position = -203 score = 5.4157 sequence = CCACTATATCTTGTGT Site: position = -172 score = 5.08204 sequence = ACACAAGATATAGTTT Gene: HAPS_1341: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
nrdA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0827: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0150: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165 Gene: HAPS_1342: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)

CRON 3.
nrdD	* Haemophilus influenzae Rd KW20 Site: position = -55 score = 4.33657 sequence = GATCTATATATAGTGC Site: position = -87 score = 5.47531 sequence = ACACTACATATTGTGT Site: position = -23 score = 5.14133 sequence = ACACTATATATTGGAG Gene: HI0075: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Aggregatibacter aphrophilus NJ8700 Site: position = -54 score = 4.87085 sequence = TATCTATATATAGTAT Site: position = -86 score = 5.32675 sequence = ACACTATATGTTGTGT Gene: NT05HA_0064: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Pasteurella multocida subsp. multocida str. Pm70 Site: position = -56 score = 5.18157 sequence = TAACTATATATAGTAT Site: position = -87 score = 5.52136 sequence = ACACTATATCTTGTGG Gene: PM0940: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Mannheimia succiniciproducens MBEL55E Site: position = -22 score = 4.63558 sequence = ACACTACATATAGATT Site: position = -54 score = 4.82972 sequence = TTTCTATATATAGTGT Gene: MS0633: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Actinobacillus succinogenes 130Z Site: position = -139 score = 5.52136 sequence = ACACAATATCTTGTGG Site: position = -54 score = 4.61038 sequence = GATCTATATATAGTAT Site: position = -22 score = 4.70261 sequence = ACACTACATATAGGTG Gene: Asuc_1407: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Haemophilus somnus 2336 Site: position = -25 score = 4.2908 sequence = ACGCAACATATAGGTT Site: position = -56 score = 4.96187 sequence = TAACAATATATAGTGA Site: position = -87 score = 5.55244 sequence = ACACAATATATAGTGG Gene: HSM_0537: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Actinobacillus pleuropneumoniae serovar 7 str. AP76 Gene: APP7_0166: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Haemophilus ducreyi 35000HP Gene: HD0393: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Haemophilus parasuis SH0165 Gene: HAPS_1167: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Asuc_1408	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z Gene: Asuc_1408: hypothetical protein	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	hypothetical protein
nrdG	Haemophilus influenzae Rd KW20 Gene: HI1155: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Aggregatibacter aphrophilus NJ8700 Gene: NT05HA_0062: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Pasteurella multocida subsp. multocida str. Pm70 Gene: PM0941: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Mannheimia succiniciproducens MBEL55E Gene: MS0632: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Actinobacillus succinogenes 130Z Gene: Asuc_1409: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Haemophilus somnus 2336 Gene: HSM_0538: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	* Actinobacillus pleuropneumoniae serovar 7 str. AP76 Site: position = -30 score = 4.98811 sequence = ACACAACATATAGTAA Site: position = -62 score = 5.50278 sequence = TCACAATATATTGTGT Gene: APP7_0167: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	* Haemophilus ducreyi 35000HP Site: position = -30 score = 4.85612 sequence = TAACTATATATAGTAA Site: position = -62 score = 5.71419 sequence = ACACAATATATTGTGT Gene: HD0394: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	* Haemophilus parasuis SH0165 Site: position = -55 score = 4.95755 sequence = CTACTACATATTGTGT Site: position = -23 score = 5.01447 sequence = CCACAAGATATAGTGG Gene: HAPS_1168: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NrdR - Pasteurellales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --