Regulog BirA - Oceanospirillales/Alteromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By taxonomy - Oceanospirillales/Alteromonadales
By trascription factor - BirA
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Hahella chejuensis KCTC 2396	6	2
Marinobacter aqueolei	5	2
Marinobacter sp. ELB17	7	3
Oceanobacter sp. RED65	5	1
Oceanospirillum sp. MED92
Marinomonas sp. MWYL1	7	2
Saccharophagus degradans 2-40	4	2
Teredinibacter turnerae T7901	5	2
Cellvibrio japonicus Ueda107	5	2
Chromohalobacter salexigens DSM 3043	6	1
Reinekea sp. MED297	6	2
Alcanivorax borkumensis SK2	6	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
bioB	* Hahella chejuensis KCTC 2396 Site: position = -164 score = 8.07255 sequence = CTGTTAACC-(14)-GGTTGACAG Gene: HCH_05371: Biotin synthase (EC 2.8.1.6)	* Marinobacter aqueolei Site: position = -41 score = 7.54231 sequence = CCGTAAACC-(14)-GGTTAACAG Site: position = -104 score = 8.07255 sequence = CTGTTAACC-(14)-GGTTGACAG Gene: Maqu_2756: Biotin synthase (EC 2.8.1.6)	* Marinobacter sp. ELB17 Site: position = -40 score = 7.54231 sequence = CCGTAAACC-(14)-GGTTAACAG Site: position = -102 score = 8.07255 sequence = CTGTTAACC-(14)-GGTTGACAG Gene: MELB17_06979: Biotin synthase (EC 2.8.1.6)	* Oceanobacter sp. RED65 Site: position = -152 score = 8.31812 sequence = CTGTAAACC-(14)-GGTTGACTG Gene: RED65_04570: Biotin synthase (EC 2.8.1.6)	Oceanospirillum sp. MED92 Gene: MED92_16370: Biotin synthase (EC 2.8.1.6)	* Marinomonas sp. MWYL1 Site: position = -85 score = 8.37218 sequence = TTGTAAACC-(14)-TGTTGACAG Gene: Mmwyl1_3457: Biotin synthase (EC 2.8.1.6)	* Saccharophagus degradans 2-40 Site: position = -90 score = 8.99046 sequence = TTGTAAACC-(15)-GGTTGACAG Gene: Sde_3139: Biotin synthase (EC 2.8.1.6)	* Teredinibacter turnerae T7901 Site: position = -110 score = 8.70579 sequence = TTGTAAACT-(15)-GGTTGACAA Gene: TERTU_0490: Biotin synthase (EC 2.8.1.6)	* Cellvibrio japonicus Ueda107 Site: position = -63 score = 8.46171 sequence = TAGTAAACC-(15)-GGTTGACAG Gene: CJA_0426: Biotin synthase (EC 2.8.1.6)	* Chromohalobacter salexigens DSM 3043 Site: position = -46 score = 7.31199 sequence = TGGTCAACC-(14)-AGTTGACCA Site: position = -102 score = 8.84478 sequence = TTGTCAACC-(15)-GGTTGACAT Gene: Csal_1167: Biotin synthase (EC 2.8.1.6)	* Reinekea sp. MED297 Site: position = -83 score = 6.77442 sequence = ATGTAAAGT-(15)-AATTGACAA Gene: MED297_08751: Biotin synthase (EC 2.8.1.6)	* Alcanivorax borkumensis SK2 Site: position = -83 score = 7.88985 sequence = CAGTAAACT-(16)-GGTTGACAG Gene: ABO_2220: Biotin synthase (EC 2.8.1.6)	Biotin synthase (EC 2.8.1.6)
bioF	Hahella chejuensis KCTC 2396 Gene: HCH_05370: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Marinobacter aqueolei Gene: Maqu_2755: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Marinobacter sp. ELB17 Gene: MELB17_06984: 8-amino-7-oxononanoate synthase	Oceanobacter sp. RED65 Gene: RED65_04565: 8-amino-7-oxononanoate synthase	Oceanospirillum sp. MED92 Gene: MED92_16365: 8-amino-7-oxononanoate synthase	Marinomonas sp. MWYL1 Gene: Mmwyl1_3456: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Saccharophagus degradans 2-40 Gene: Sde_3138: 8-amino-7-oxononanoate synthase	Teredinibacter turnerae T7901 Gene: TERTU_0491: 8-amino-7-oxononanoate synthase	Cellvibrio japonicus Ueda107 Gene: CJA_0427: 8-amino-7-oxononanoate synthase	Chromohalobacter salexigens DSM 3043 Gene: Csal_1166: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Reinekea sp. MED297 Gene: MED297_08756: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Alcanivorax borkumensis SK2 Gene: ABO_2219: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioH	Hahella chejuensis KCTC 2396 Gene: HCH_05369: Biotin synthesis protein BioH	Marinobacter aqueolei	Marinobacter sp. ELB17 Gene: MELB17_06989: Biotin synthesis protein BioH	Oceanobacter sp. RED65 Gene: RED65_04560: Biotin synthesis protein BioH	Oceanospirillum sp. MED92 Gene: MED92_16360: Biotin synthesis protein BioH	Marinomonas sp. MWYL1 Gene: Mmwyl1_3455: Biotin synthesis protein BioH	Saccharophagus degradans 2-40 Gene: Sde_3137: Biotin synthesis protein BioH / Biotin synthesis protein BioC	Teredinibacter turnerae T7901 Gene: TERTU_0492: Biotin synthesis protein BioH / Biotin synthesis protein BioC	Cellvibrio japonicus Ueda107 Gene: CJA_0428: Biotin synthesis protein BioH / Biotin synthesis protein BioC	Chromohalobacter salexigens DSM 3043 Gene: Csal_1165: Biotin synthesis protein BioH	Reinekea sp. MED297 Gene: MED297_08761: Biotin synthesis protein BioH	Alcanivorax borkumensis SK2 Gene: ABO_2218: Biotin synthesis protein BioH	Biotin synthesis protein BioH
bioC	Hahella chejuensis KCTC 2396 Gene: HCH_05368: Biotin synthesis protein BioC	Marinobacter aqueolei Gene: Maqu_2754: Biotin synthesis protein BioC	Marinobacter sp. ELB17 Gene: MELB17_06994: Biotin synthesis protein BioC	Oceanobacter sp. RED65 Gene: RED65_04555: Biotin synthesis protein BioC	Oceanospirillum sp. MED92 Gene: MED92_16355: Biotin synthesis protein BioC	Marinomonas sp. MWYL1 Gene: Mmwyl1_3454: Biotin synthesis protein BioC	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	Chromohalobacter salexigens DSM 3043 Gene: Csal_1164: Biotin synthesis protein BioC	Reinekea sp. MED297 Gene: MED297_08766: Biotin synthesis protein BioC	Alcanivorax borkumensis SK2 Gene: ABO_2217: Biotin synthesis protein BioC	Biotin synthesis protein BioC
bioD	Hahella chejuensis KCTC 2396 Gene: HCH_05366: Dethiobiotin synthetase (EC 6.3.3.3)	Marinobacter aqueolei Gene: Maqu_2753: Dethiobiotin synthetase (EC 6.3.3.3)	Marinobacter sp. ELB17 Gene: MELB17_06999: Dethiobiotin synthetase (EC 6.3.3.3)	Oceanobacter sp. RED65 Gene: RED65_04550: Dethiobiotin synthetase (EC 6.3.3.3)	Oceanospirillum sp. MED92 Gene: MED92_16350: Dethiobiotin synthetase (EC 6.3.3.3)	Marinomonas sp. MWYL1 Gene: Mmwyl1_3453: Dethiobiotin synthetase (EC 6.3.3.3)	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901 Gene: TERTU_0493: Dethiobiotin synthetase (EC 6.3.3.3)	Cellvibrio japonicus Ueda107 Gene: CJA_0429: Dethiobiotin synthetase (EC 6.3.3.3)	Chromohalobacter salexigens DSM 3043 Gene: Csal_1163: Dethiobiotin synthetase (EC 6.3.3.3)	Reinekea sp. MED297 Gene: MED297_08771: Dethiobiotin synthetase (EC 6.3.3.3)	Alcanivorax borkumensis SK2 Gene: ABO_2216: Dethiobiotin synthetase (EC 6.3.3.3)	Dethiobiotin synthetase (EC 6.3.3.3)
bioA	Hahella chejuensis KCTC 2396 Gene: HCH_01529: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Marinobacter aqueolei Gene: Maqu_3049: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	* Marinobacter sp. ELB17 Site: position = -78 score = 6.98106 sequence = CTGTTAACT-(14)-GGTTAACAG Gene: MELB17_04752: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Oceanobacter sp. RED65 Gene: RED65_10464: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Oceanospirillum sp. MED92 Gene: MED92_16420: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Marinomonas sp. MWYL1 Gene: Mmwyl1_3459: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Saccharophagus degradans 2-40 Gene: Sde_2227: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Teredinibacter turnerae T7901 Gene: TERTU_1207: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Cellvibrio japonicus Ueda107 Gene: CJA_2079: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Chromohalobacter salexigens DSM 3043 Gene: Csal_1162: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Reinekea sp. MED297 Gene: MED297_01550: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Alcanivorax borkumensis SK2 Gene: ABO_0256: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
COG1040	* Hahella chejuensis KCTC 2396 Site: position = 30 score = 8.07255 sequence = CTGTCAACC-(14)-GGTTAACAG Gene: HCH_05372: Competence protein F homolog, phosphoribosyltransferase domain	* Marinobacter aqueolei Site: position = 21 score = 8.07255 sequence = CTGTCAACC-(14)-GGTTAACAG Site: position = -42 score = 7.54231 sequence = CTGTTAACC-(14)-GGTTTACGG Gene: Maqu_2757: Competence protein F homolog, phosphoribosyltransferase domain	* Marinobacter sp. ELB17 Site: position = 21 score = 8.07255 sequence = CTGTCAACC-(14)-GGTTAACAG Site: position = -41 score = 7.54231 sequence = CTGTTAACC-(14)-GGTTTACGG Gene: MELB17_06974: Competence protein F homolog, phosphoribosyltransferase domain	Oceanobacter sp. RED65	Oceanospirillum sp. MED92 Gene: MED92_16375: Competence protein F homolog, phosphoribosyltransferase domain	* Marinomonas sp. MWYL1 Site: position = 15 score = 8.37218 sequence = CTGTCAACA-(14)-GGTTTACAA Gene: Mmwyl1_3458: Competence protein F homolog, phosphoribosyltransferase domain	* Saccharophagus degradans 2-40 Site: position = -33 score = 8.99046 sequence = CTGTCAACC-(15)-GGTTTACAA Gene: Sde_3140: Competence protein F homolog, phosphoribosyltransferase domain	* Teredinibacter turnerae T7901 Site: position = -49 score = 8.70579 sequence = TTGTCAACC-(15)-AGTTTACAA Gene: TERTU_0489: Competence protein F homolog, phosphoribosyltransferase domain	* Cellvibrio japonicus Ueda107 Site: position = -147 score = 8.46171 sequence = CTGTCAACC-(15)-GGTTTACTA Gene: CJA_0425: Competence protein F homolog, phosphoribosyltransferase domain	Chromohalobacter salexigens DSM 3043 Gene: Csal_2296: Competence protein F homolog, phosphoribosyltransferase domain	* Reinekea sp. MED297 Site: position = -231 score = 6.77442 sequence = TTGTCAATT-(15)-ACTTTACAT Gene: MED297_08746: Competence protein F homolog, phosphoribosyltransferase domain	* Alcanivorax borkumensis SK2 Site: position = 4 score = 7.88985 sequence = CTGTCAACC-(16)-AGTTTACTG Gene: ABO_2221: Competence protein F homolog, phosphoribosyltransferase domain	Competence protein F homolog, phosphoribosyltransferase domain

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Oceanospirillales/Alteromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --