Propagated regulons of Streptococcus agalactiae 18RS21
| Type | Regulator | Effector | Pathway | Genes | Sites |
|---|---|---|---|---|---|
| TF | AdcR | Zinc ion, (Zn2+) | Zinc homeostasis | 3 | 3 |
| TF | ArgR | Arginine | Arginine biosynthesis; Arginine degradation | 3 | 10 |
| TF | BirA | Biotin | Biotin biosynthesis | 3 | 3 |
| TF | CcpA | Fructose-1,6-bisphosphate; HPr, phosphocarrier protein | Global catabolite repression | 63 | 84 |
| TF | CmbR | O-acetyl-L-serine | Cysteine metabolism | 7 | 11 |
| TF | CodY | Guanosine triphosphate; Branched-chain amino acids | Amino acid metabolism | 16 | 19 |
| TF | CopR | Copper ion, (Cu2+) | Copper homeostasis | 1 | 2 |
| TF | CtsR | Heat shock | Heat shock response | 4 | 4 |
| TF | FabT | Long-chain acyl-ACP | Fatty acid biosynthesis | 4 | 4 |
| TF | GlnR | Phosphorylated NtrB, signal histidine kinase | Nitrogen assimilation | 3 | 3 |
| TF | HrcA | Heat shock | Heat shock response | 3 | 4 |
| TF | LacR | D-galactose-6-phosphate | Lactose utilization; Galactose utilization | 2 | 10 |
| TF | MalR | Maltose | Maltose utilization; Maltodextrin utilization | 2 | 2 |
| TF | MntR | Manganese ion, (Mn2+) | Manganese homeostasis | 3 | 4 |
| TF | MtaR | Homocysteine | Methionine metabolism | 2 | 3 |
| TF | NagR | N-acetylglucosamine-6-phosphate | N-acetylglucosamine utilization | 2 | 2 |
| TF | NanR | N-acetylneuraminic acid | Sialic acid utilization | 1 | 1 |
| TF | NiaR | Niacin | NAD biosynthesis | 1 | 1 |
| TF | NmlR | Methylglyoxal; Formaldehyde; Nitric oxide | Carbonyl stress response | 2 | 2 |
| TF | NrdR | Deoxyribonucleotides | Deoxyribonucleotide biosynthesis | 1 | 1 |
| TF | PerR | Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide | Iron homeostasis; Manganese homeostasis; Oxidative stress response | 4 | 6 |
| TF | PflR | Formate metabolism | 2 | 2 | |
| TF | PurR | 5-phosphoribosyl 1-pyrophosphate | Purine metabolism | 5 | 8 |
| TF | RbsR2 | Ribose | Ribose utilization | 1 | 4 |
| TF | RegR | Hyaluronate oligosaccharide phosphate | Hyaluronate utilization | 1 | 1 |
| TF | Rex | NADH | Energy metabolism | 10 | 24 |
| TF | SAG1808 | Sugar utilization | 1 | 2 | |
| TF | SAG1910 | unknown | 3 | 3 | |
| TF | ScrR | Sucrose-6-phosphate | Sucrose utilization | 2 | 2 |
| TF | SczA | Zinc ion, (Zn2+) | Zinc resistance | 1 | 1 |
| TF | SgaR | HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component | Ascorbate utilization | 2 | 3 |
| TF | SgaR2 | SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein | Ascorbate utilization | 1 | 1 |
| TF | SPy1285 | Transport | 1 | 1 | |
| TF | YjdR | Multidrug resistance | 1 | 1 | |