Propagation of CodY regulog to Streptococcus agalactiae 18RS21
| Source regulog: | CodY - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | CodY |
| Regulation mode: | repressor (activator) |
| Biological process: | Amino acid metabolism |
| Effector: | Guanosine triphosphate; Branched-chain amino acids |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus agalactiae 18RS21 |
| Orthologous TF(s) | SAJ_1637 |
| Regulated genes | 16 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -115
Score: 5.6 Sequence: AATTTTCTGAATATT
Locus tag: SAJ_1948
|
||||
| SAJ_1948 | -115 | 5.6 | AATTTTCTGAATATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gldA2 | ||||
| Ortholog function: Glycerol dehydrogenase (EC 1.1.1.6) | ||||
| Streptococcus agalactiae 2603V/R | SAG2046 | -115 | 5.6 | AATTTTCTGAATATT |
| Streptococcus mutans UA159 | SMU.1309c | -154 | 5 | AATCTTCTGAATATT |
|
Position: -310
Score: 5 Sequence: AATTTTCAGTATATT
Position: -85
Score: 5.3 Sequence: AAAATTCAGAAAATT
Locus tag: SAJ_1955
|
||||
| SAJ_1955 | -310 | 5 | AATTTTCAGTATATT | |
| -85 | 5.3 | AAAATTCAGAAAATT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: scpC | ||||
| Ortholog function: Serine endopeptidase ScpC (EC 3.4.21.-) | ||||
| Streptococcus agalactiae 2603V/R | SAG2053 | -85 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_0748 | -100 | 5 | AATTTTCAGAAAAAA |
| Streptococcus suis 05ZYH33 | SSU05_0812 | -146 | 5.1 | AATTTTCAGAATATA |
|
Position: -96
Score: 4.6 Sequence: AATATTCTGAATTTA
Locus tag: SAJ_0781
|
||||
| SAJ_0781 | -96 | 4.6 | AATATTCTGAATTTA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gluQ | ||||
| Ortholog function: Glutamate ABC transporter, ATP-binding protein | ||||
| Streptococcus agalactiae 2603V/R | SAG0718 | -96 | 4.6 | AATATTCTGAATTTA |
| Streptococcus gallolyticus UCN34 | GALLO_1555 | -114 | 5.1 | AATTTTCTGAATATA |
| Streptococcus mutans UA159 | SMU.1519 | -101 | 5.1 | AATTTTCTGATAATA |
|
Position: -177
Score: 4.7 Sequence: AATATTCTGCTAATT
Locus tag: SAJ_1046
|
||||
| SAJ_1046 | -177 | 4.7 | AATATTCTGCTAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: fatD | ||||
| Ortholog function: Iron-siderophore ABC transporter, permease protein 1 | ||||
| Streptococcus agalactiae 2603V/R | SAG1010 | -177 | 4.7 | AATATTCTGCTAATT |
| Streptococcus gallolyticus UCN34 | GALLO_0871 | -109 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1869 | -80 | 5.2 | AATTGTCAGAAATTT |
|
Position: -127
Score: 5.1 Sequence: AATTTTCAGATTTTT
Locus tag: SAJ_0819
|
||||
| SAJ_0819 | -127 | 5.1 | AATTTTCAGATTTTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pepF | ||||
| Ortholog function: Oligoendopeptidase F | ||||
| Streptococcus agalactiae 2603V/R | SAG0758 | -127 | 5.1 | AATTTTCAGATTTTT |
| Streptococcus gallolyticus UCN34 | GALLO_1516 | -220 | 5.1 | AATTTTCTGATTTTT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0342 | 22 | 4.5 | AATTTCCAGAAAATG |
| Streptococcus sanguinis SK36 | SSA_2051 | 22 | 4.5 | AATTTCCAGAAAATG |
| Streptococcus uberis 0140J | SUB0601 | -154 | 4.8 | CTTTTTCTGAAAATT |
|
Position: -96
Score: 5.1 Sequence: AAAAATCTGAAAATT
Locus tag: SAJ_0820
|
||||
| SAJ_0820 | -96 | 5.1 | AAAAATCTGAAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: ppc | ||||
| Ortholog function: Phosphoenolpyruvate carboxylase (EC 4.1.1.31) | ||||
| Streptococcus agalactiae 2603V/R | SAG0759 | -96 | 5.1 | AAAAATCTGAAAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0621 | -167 | 4.5 | CATTTTCAGGAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1515 | -132 | 5.1 | AAAAATCAGAAAATT |
| Streptococcus thermophilus CNRZ1066 | str0718 | -108 | 4.9 | AAAAGTCAGAAAATT |
| Streptococcus uberis 0140J | SUB0602 | -55 | 4.8 | AATTTTCAGAAAAAG |
|
Position: -52
Score: 4.9 Sequence: AATTTTCTGACTTTT
Locus tag: SAJ_0435
|
||||
| SAJ_0435 | -52 | 4.9 | AATTTTCTGACTTTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: thrA | ||||
| Ortholog function: Aspartokinase (EC 2.7.2.4) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_0783 | -71 | 5.6 | AATTATCTGAAAATT |
| Lactococcus lactis subsp. lactis Il1403 | L0097 | -70 | 5.6 | AATTATCTGAAAATT |
| Streptococcus agalactiae 2603V/R | SAG0339 | -52 | 4.9 | AATTTTCTGACTTTT |
| Streptococcus gallolyticus UCN34 | GALLO_0331 | -52 | 5.3 | AATTTTCAGAATTTT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1701 | -38 | 4.5 | AATTGTTTGAATAAT |
| Streptococcus mutans UA159 | SMU.1748 | -53 | 5.3 | AATTTTCTGAATTTT |
| Streptococcus sanguinis SK36 | SSA_1943 | -47 | 5.3 | AATTTTCAGAATTTT |
| Streptococcus suis 05ZYH33 | SSU05_1811 | -123 | 4.6 | GTTTTTCTGAAATTT |
| Streptococcus thermophilus CNRZ1066 | str0378 | -56 | 5.1 | AATTATCAGAATTTT |
| Streptococcus uberis 0140J | SUB0316 | -26 | 5 | AATATTCATAAAATT |
|
Position: -128
Score: 5.2 Sequence: AACTTTCTGAAAATT
Locus tag: SAJ_0240
|
||||
| SAJ_0240 | -128 | 5.2 | AACTTTCTGAAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: rpoB | ||||
| Ortholog function: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) | ||||
| Streptococcus agalactiae 2603V/R | SAG0160 | -128 | 5.2 | AACTTTCTGAAAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0131 | -91 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_0084 | -165 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1927 | -222 | 5.4 | ATTTTTCTGAAAATT |
| Streptococcus mitis B6 | smi_1847 | -113 | 5 | AAGATTCTGAAAATT |
| Streptococcus mutans UA159 | SMU.1990 | -84 | 5.3 | AAAATTCTGAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1961 | -112 | 5 | AAGATTCTGAAAATT |
| Streptococcus pyogenes M1 GAS | SPy0098 | -91 | 5.2 | AATATTCTAAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0121 | -276 | 4.6 | AAGATTCTAAAAATT |
| Streptococcus thermophilus CNRZ1066 | str1868 | -171 | 4.6 | AAAGTTCTAAAAATT |
| Streptococcus uberis 0140J | SUB0115 | -90 | 4.6 | AAGATTCTAAAAATT |
|
Position: -48
Score: 4.8 Sequence: AATATTCAGAATGTT
Locus tag: SAJ_0390
|
||||
| SAJ_0390 | -48 | 4.8 | AATATTCAGAATGTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pepC | ||||
| Ortholog function: Aminopeptidase C (EC 3.4.22.40) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_2073 | -125 | 4.8 | ATTTTTTTGATAATT |
| Lactococcus lactis subsp. lactis Il1403 | L130687 | -125 | 4.8 | ATTTTTTTGATAATT |
| Streptococcus agalactiae 2603V/R | SAG0297 | -48 | 4.8 | AATATTCAGAATGTT |
| Streptococcus gallolyticus UCN34 | GALLO_0478 | -125 | 4.7 | AAATGTCAGAATTTT |
| Streptococcus thermophilus CNRZ1066 | str0229 | -57 | 5.1 | AATTTTCAGAAATTA |
|
Position: -56
Score: 5.3 Sequence: AATATTCTGATAATT
Locus tag: SAJ_1560
|
||||
| SAJ_1560 | -56 | 5.3 | AATATTCTGATAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: livK | ||||
| Ortholog function: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG1582 | -56 | 5.3 | AATATTCTGATAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0443 | -98 | 4.9 | ATTTTTCAAAATATT |
| -65 | 5.6 | AATTTTCTGATAATT | ||
| Streptococcus gallolyticus UCN34 | GALLO_1760 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1630 | -66 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mitis B6 | smi_1415 | -61 | 5.6 | AATTTTCTGATAATT |
| Streptococcus mutans UA159 | SMU.1669 | -66 | 5.3 | AATATTCAGATAATT |
| Streptococcus pneumoniae TIGR4 | SP_0749 | -60 | 5.6 | AATTTTCTGATAATT |
| Streptococcus sanguinis SK36 | SSA_1729 | -65 | 5.2 | AATTGTCAGATAATT |
| Streptococcus suis 05ZYH33 | SSU05_1548 | -64 | 5.6 | AATTTTCAGATAATT |
| Streptococcus thermophilus CNRZ1066 | str0359 | -65 | 5.6 | AATTTTCTGATAATT |
| Streptococcus uberis 0140J | SUB0432 | -66 | 5.6 | AATTTTCTGATAATT |
|
Position: -85
Score: 4.6 Sequence: AAAATTCAAAAAAAT
Locus tag: SAJ_0961
|
||||
| SAJ_0961 | -85 | 4.6 | AAAATTCAAAAAAAT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: cas9 | ||||
| Ortholog function: CRISPR/Cas system-associated protein Cas9 | ||||
| Streptococcus agalactiae 2603V/R | SAG0894 | -85 | 4.6 | AAAATTCAAAAAAAT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1330 | -86 | 5.2 | AATATTTAGAAAATT |
|
Position: -55
Score: 4.9 Sequence: AAAATTCTGACAATT
Locus tag: SAJ_1345
|
||||
| SAJ_1345 | -55 | 4.9 | AAAATTCTGACAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gdhA | ||||
| Ortholog function: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) | ||||
| Streptococcus agalactiae 2603V/R | SAG1335 | -55 | 4.9 | AAAATTCTGACAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0823 | -61 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1090 | -65 | 5.3 | AAAATTCAGAAAATT |
| Streptococcus gallolyticus UCN34 | GALLO_1293 | -78 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0276 | -95 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus mitis B6 | smi_0814 | -95 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus mutans UA159 | SMU.913 | -68 | 5.6 | AATATTCAGAAAATT |
| Streptococcus pneumoniae TIGR4 | SP_1306 | -94 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus sanguinis SK36 | SSA_0371 | -182 | 5.5 | AATTTTTAGAAAATT |
| Streptococcus suis 05ZYH33 | SSU05_0252 | -45 | 5.1 | AATTGTCAGACAATT |
| Streptococcus thermophilus CNRZ1066 | str0430 | -52 | 5 | AAGATTCTGAAAATT |
| Streptococcus uberis 0140J | SUB0762 | -60 | 5.6 | AATATTCTGAAAATT |
|
Position: -127
Score: 5 Sequence: AATTTTGAGAATATT
Locus tag: SAJ_1638
|
||||
| SAJ_1638 | -127 | 5 | AATTTTGAGAATATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: alaT | ||||
| Ortholog function: Aspartate aminotransferase (EC 2.6.1.1) | ||||
| Streptococcus agalactiae 2603V/R | SAG1676 | -46 | 5 | AATTTTGAGAATATT |
|
Position: -72
Score: 4.6 Sequence: ATATGTCAGATAATT
Locus tag: SAJ_0873
|
||||
| SAJ_0873 | -72 | 4.6 | ATATGTCAGATAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: gapN | ||||
| Ortholog function: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9) | ||||
| Streptococcus agalactiae 2603V/R | SAG0823 | -72 | 4.6 | ATATGTCAGATAATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1419 | -87 | 4.9 | AATTTTCTGATACTT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0766 | -87 | 4.6 | AATTTTCAGACTCTT |
| Streptococcus gallolyticus UCN34 | GALLO_0746 | -87 | 5.3 | AATTTTCTGAATTTT |
| Streptococcus mutans UA159 | SMU.676 | -89 | 5.3 | AATTTTCTGAATTTT |
| Streptococcus pneumoniae TIGR4 | SP_1119 | -55 | 5.2 | GATTTTCTGAAAATT |
| Streptococcus pyogenes M1 GAS | SPy1371 | -87 | 5.3 | AATTTTCAGATATTT |
| Streptococcus sanguinis SK36 | SSA_0774 | -53 | 5.8 | AATTTTCAGAAAATT |
| Streptococcus thermophilus CNRZ1066 | str1263 | -89 | 5 | AATTTTCTGAATACT |
| Streptococcus uberis 0140J | SUB1220 | -87 | 5.4 | AATTTTCAGACAATT |