Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Collection of regulogs for Leu_leader (RF00512) RNA regulatory element

The leucine operon leader is an RNA element that was found upstream of some leucine biosynthesis leuABCD operons in Escherichia coli and related bacteria and that is involved in the amino acid dependent attenuation of their transcription [6186194]. The leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure. The leader also codes for very short peptide sequence that is rich in Leucine. The terminator structure is recognized as a termination signal for RNA polymerase and the operon is not transcribed. This structure forms when the cell has an excess of leucine and ribosome movement over the leader transcript is not impeded. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Proteobacteria Leu_leader - Enterobacteriales 12 (12) 12
Proteobacteria Leu_leader - Pasteurellales 4 (9) 5
Proteobacteria Leu_leader - Shewanellaceae 16 (16) 16
Proteobacteria Leu_leader - Vibrionales 10 (10) 10