Regulog Leu_leader - Enterobacteriales

Properties
Regulator type:	RNA regulatory element
Name:	Leu_leader
RFAM:	RF00512
Regulation mode:
Biological process:	Branched-chain amino acid biosynthesis
Effector:
Phylum:	Proteobacteria

Member of regulog collections

By taxonomy - Enterobacteriales
By RNA motif - Leu_leader
By pathway - Branched-chain amino acid biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	4	1
Salmonella typhimurium LT2	4	1
Citrobacter koseri ATCC BAA-895	4	1
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	4	1
Enterobacter sp. 638	4	1
Erwinia amylovora ATCC 49946	4	1
Yersinia pestis KIM	5	1
Serratia proteamaculans 568	4	1
Erwinia carotovora subsp. atroseptica SCRI1043	4	1
Edwardsiella tarda EIB202	4	1
Proteus mirabilis HI4320	4	1
Photorhabdus luminescens subsp. laumondii TTO1	4	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
tnp	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -238 score = 116.52 sequence = AGAAGCTGAAATTTA... Gene: y3644: IS and transposon related functions	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	IS and transposon related functions
leuA	* Escherichia coli str. K-12 substr. MG1655 Site: position = -194 score = 138.54 sequence = TCTGGAGCTGATTTA... Gene: b0074: 2-isopropylmalate synthase (EC 2.3.3.13)	* Salmonella typhimurium LT2 Site: position = -189 score = 141.65 sequence = GCTGGAGCTGAATTA... Gene: STM0113: 2-isopropylmalate synthase (EC 2.3.3.13)	* Citrobacter koseri ATCC BAA-895 Site: position = -190 score = 136.4 sequence = TGGAGTTGATTTAAT... Gene: CKO_03304: 2-isopropylmalate synthase (EC 2.3.3.13)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -198 score = 87.46 sequence = TCTGGAGTTTGACGC... Gene: KPN_00080: 2-isopropylmalate synthase (EC 2.3.3.13)	* Enterobacter sp. 638 Site: position = -192 score = 130.27 sequence = TCTGGAGCATGATTC... Gene: Ent638_0622: 2-isopropylmalate synthase (EC 2.3.3.13)	* Erwinia amylovora ATCC 49946 Site: position = -193 score = 92.45 sequence = TATAAGGTTTGAGCC... Gene: EAM_0683: 2-isopropylmalate synthase (EC 2.3.3.13)	Yersinia pestis KIM Gene: y3645: 2-isopropylmalate synthase (EC 2.3.3.13)	* Serratia proteamaculans 568 Site: position = -190 score = 97.34 sequence = TAGAGAGCTGAACCG... Gene: Spro_0745: 2-isopropylmalate synthase (EC 2.3.3.13)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -195 score = 119.89 sequence = GAGACACGACACTAT... Gene: ECA3831: 2-isopropylmalate synthase (EC 2.3.3.13)	* Edwardsiella tarda EIB202 Site: position = -108 score = 31.74 sequence = GCTAGAATTCACCCA... Gene: ETAE_0621: 2-isopropylmalate synthase (EC 2.3.3.13)	* Proteus mirabilis HI4320 Site: position = -189 score = 65.29 sequence = GTAAGGATGTTTCAT... Gene: PMI2084: 2-isopropylmalate synthase (EC 2.3.3.13)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -194 score = 51.16 sequence = TCGATATGATTCACT... Gene: plu3673: 2-isopropylmalate synthase (EC 2.3.3.13)	2-isopropylmalate synthase (EC 2.3.3.13)
leuB	Escherichia coli str. K-12 substr. MG1655 Gene: b0073: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Salmonella typhimurium LT2 Gene: STM0112: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Citrobacter koseri ATCC BAA-895 Gene: CKO_03305: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00079: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Enterobacter sp. 638 Gene: Ent638_0621: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Erwinia amylovora ATCC 49946 Gene: EAM_0682: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Yersinia pestis KIM Gene: y3646: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Serratia proteamaculans 568 Gene: Spro_0744: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3832: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Edwardsiella tarda EIB202 Gene: ETAE_0620: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Proteus mirabilis HI4320 Gene: PMI2085: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu3674: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	3-isopropylmalate dehydrogenase (EC 1.1.1.85)
leuC	Escherichia coli str. K-12 substr. MG1655 Gene: b0072: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Salmonella typhimurium LT2 Gene: STM0111: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Citrobacter koseri ATCC BAA-895 Gene: CKO_03306: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00078: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Enterobacter sp. 638 Gene: Ent638_0620: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Erwinia amylovora ATCC 49946 Gene: EAM_0681: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Yersinia pestis KIM Gene: y3647: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Serratia proteamaculans 568 Gene: Spro_0743: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3833: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Edwardsiella tarda EIB202 Gene: ETAE_0619: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Proteus mirabilis HI4320 Gene: PMI2086: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu3675: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD	Escherichia coli str. K-12 substr. MG1655 Gene: b0071: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Salmonella typhimurium LT2 Gene: STM0110: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Citrobacter koseri ATCC BAA-895 Gene: CKO_03307: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00077: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Enterobacter sp. 638 Gene: Ent638_0619: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Erwinia amylovora ATCC 49946 Gene: EAM_0680: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Yersinia pestis KIM Gene: y3648: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Serratia proteamaculans 568 Gene: Spro_0742: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3834: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Edwardsiella tarda EIB202 Gene: ETAE_0618: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Proteus mirabilis HI4320 Gene: PMI2087: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu3676: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Leu_leader - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --