Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing leuD gene

Properties
Regulator type: RNA regulatory element
Name: Leu_leader
RFAM: RF00512
Regulation mode:
Biological process: Branched-chain amino acid biosynthesis
Effector:
Phylum: Proteobacteria
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Citrobacter koseri ATCC BAA-895
Position: -190
Score: 136.4
Sequence: TGGAGTTGATTTAAT...
Locus tag: CKO_03304
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: CKO_03305
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: CKO_03306
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: CKO_03307
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -190 136.4 TGGAGTTGATTTAAT... CKO_03304
Edwardsiella tarda EIB202
Position: -108
Score: 31.74
Sequence: GCTAGAATTCACCCA...
Locus tag: ETAE_0621
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: ETAE_0620
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: ETAE_0619
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: ETAE_0618
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -108 31.7 GCTAGAATTCACCCA... ETAE_0621
Enterobacter sp. 638
Position: -192
Score: 130.27
Sequence: TCTGGAGCATGATTC...
Locus tag: Ent638_0622
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Ent638_0621
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Ent638_0620
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Ent638_0619
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -192 130.3 TCTGGAGCATGATTC... Ent638_0622
Erwinia amylovora ATCC 49946
Position: -193
Score: 92.45
Sequence: TATAAGGTTTGAGCC...
Locus tag: EAM_0683
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: EAM_0682
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: EAM_0681
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: EAM_0680
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -193 92.4 TATAAGGTTTGAGCC... EAM_0683
Erwinia carotovora subsp. atroseptica SCRI1043
Position: -195
Score: 119.89
Sequence: GAGACACGACACTAT...
Locus tag: ECA3831
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: ECA3832
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: ECA3833
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: ECA3834
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -195 119.9 GAGACACGACACTAT... ECA3831
Escherichia coli str. K-12 substr. MG1655
Position: -194
Score: 138.54
Sequence: TCTGGAGCTGATTTA...
Locus tag: b0074
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: b0073
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: b0072
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: b0071
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -194 138.5 TCTGGAGCTGATTTA... b0074
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Position: -198
Score: 87.46
Sequence: TCTGGAGTTTGACGC...
Locus tag: KPN_00080
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: KPN_00079
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: KPN_00078
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: KPN_00077
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -198 87.5 TCTGGAGTTTGACGC... KPN_00080
Photorhabdus luminescens subsp. laumondii TTO1
Position: -194
Score: 51.16
Sequence: TCGATATGATTCACT...
Locus tag: plu3673
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: plu3674
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: plu3675
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: plu3676
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -194 51.2 TCGATATGATTCACT... plu3673
Proteus mirabilis HI4320
Position: -189
Score: 65.29
Sequence: GTAAGGATGTTTCAT...
Locus tag: PMI2084
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: PMI2085
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: PMI2086
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: PMI2087
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -189 65.3 GTAAGGATGTTTCAT... PMI2084
Salmonella typhimurium LT2
Position: -189
Score: 141.65
Sequence: GCTGGAGCTGAATTA...
Locus tag: STM0113
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: STM0112
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: STM0111
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: STM0110
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -189 141.6 GCTGGAGCTGAATTA... STM0113
Serratia proteamaculans 568
Position: -190
Score: 97.34
Sequence: TAGAGAGCTGAACCG...
Locus tag: Spro_0745
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: Spro_0744
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: Spro_0743
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: Spro_0742
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA-leuB-leuC-leuD -190 97.3 TAGAGAGCTGAACCG... Spro_0745
Yersinia pestis KIM
Position: -238
Score: 116.52
Sequence: AGAAGCTGAAATTTA...
Locus tag: y3644
Name: null
Funciton: IS and transposon related functions
Locus tag: y3645
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: y3646
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: y3647
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: y3648
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
y3644-leuA-leuB-leuC-leuD -238 116.5 AGAAGCTGAAATTTA... y3644
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