Regulon of GlxR in Corynebacterium urealyticum DSM 7109
| Regulator type: | Transcription factor |
| TF locus tag: | cur_1867 |
| Regulator family: | CRP |
| Regulation mode: | repressor (activator) |
| Biological process: | Energy metabolism; Carbohydrate metabolism |
| Effector: | Cyclic 3',5'-AMP |
| Regulog: | GlxR - Corynebacteriaceae |
| Statistics of regulated genes: | |
| - Genes | 84 |
| - Operons | 49 |
| Visualization: | |
|
Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Corynebacteriaceae
- By TF family - CRP
- By effector - Cyclic 3',5'-AMP
- By pathway - Energy metabolism
- By pathway - Carbohydrate metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
|
Position: -139
Score: 4.1 Sequence: TGTGACCCCCGTAACA
Locus tag: cur_1871
Name: whiB4 Funciton: Predicted transcriptional regulator, WhiB family |
|||
|
whiB4
|
Predicted transcriptional regulator, WhiB family
|
||
|
Position: -50
Score: 3.9 Sequence: AGTGACCAAGGTCTCC
Locus tag: cur_0201
Name: sdhC Funciton: Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1)
Locus tag: cur_0202
Name: sdhA Funciton: Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1)
Locus tag: cur_0203
Name: sdhB Funciton: Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1)
Locus tag: cur_0204
Name: cg0448 Funciton: Conserved hypothetical protein |
|||
|
sdhC
|
Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1)
|
||
|
sdhA
|
Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1)
|
||
|
sdhB
|
Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1)
|
||
|
cg0448
|
Conserved hypothetical protein
|
||
|
Position: -4
Score: 3.4 Sequence: AGTAATGAGCAGCACA
Locus tag: cur_1726
Name: famR Funciton: Fatty acids metabolism transcriptional regulator FamR, MarR family |
|||
|
famR
|
Fatty acids metabolism transcriptional regulator FamR, MarR family
|
||
|
Position: -144
Score: 4 Sequence: GGTGTTGGGGGTCACA
Locus tag: cur_1135
Name: fadA2 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9) |
|||
|
fadA2
|
3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
|
||
|
Position: -202
Score: 3.8 Sequence: CGTGATGAAGGCCACC
Locus tag: cur_0740
Name: fadD11 Funciton: Acyl-CoA synthetase, AMP-binding protein |
|||
|
fadD11
|
Acyl-CoA synthetase, AMP-binding protein
|
||
|
Position: -26
Score: 3.4 Sequence: TGGGCTGAACGCCACA
Locus tag: cur_1605
Name: actA Funciton: Butyryl-CoA:acetate-CoA transferase (EC 2.8.3.8) |
|||
|
actA
|
Butyryl-CoA:acetate-CoA transferase (EC 2.8.3.8)
|
||
|
Position: -241
Score: 4.2 Sequence: AGTGTTTCATATCACT
Locus tag: cur_1766
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
|||
|
metE
|
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
|
||
|
Position: 74
Score: 3.6 Sequence: GGTGGCAGACGTCACC
Locus tag: cur_1021
Name: acn Funciton: Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
Locus tag: cur_1020
Name: acnR Funciton: Aconitase gene transcriptional regulator AcnR, TetR family |
|||
|
acn
|
Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
|
||
|
acnR
|
Aconitase gene transcriptional regulator AcnR, TetR family
|
||
|
Position: -130
Score: 4.1 Sequence: TGTAACCAAGCTCACA
Locus tag: cur_0497
Name: cg0879 Funciton: Conserved hypothetical protein |
|||
|
cg0879
|
Conserved hypothetical protein
|
||
|
Position: -159
Score: 3.8 Sequence: TGTGAGCTACGCGACA
Position: -80
Score: 4.1 Sequence: TGAGAACTGAACCACA
Locus tag: cur_1558
Name: serC Funciton: Phosphoserine aminotransferase (EC 2.6.1.52) |
|||
|
serC
|
Phosphoserine aminotransferase (EC 2.6.1.52)
|
||
|
Position: -119
Score: 3.5 Sequence: GGTGATTTTGCGCACG
Locus tag: cur_0562
Name: rpf2 Funciton: Cell wall-binding protein
Locus tag: cur_0563
Name: ksgA Funciton: Dimethyladenosine transferase (EC 2.1.1.-)
Locus tag: cur_0564
Name: ispE Funciton: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)
Locus tag: cur_0565
Name: cg1040 Funciton: Predicted ABC transporter, ATP-binding protein |
|||
|
rpf2
|
Cell wall-binding protein
|
||
|
ksgA
|
Dimethyladenosine transferase (EC 2.1.1.-)
|
||
|
ispE
|
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)
|
||
|
cg1040
|
Predicted ABC transporter, ATP-binding protein
|
||
|
Position: -97
Score: 3.4 Sequence: TGCGTTGCGCCCCACA
Locus tag: cur_0603
Name: coaA Funciton: Pantothenate kinase (EC 2.7.1.33) |
|||
|
coaA
|
Pantothenate kinase (EC 2.7.1.33)
|
||
|
Position: -33
Score: 4.8 Sequence: AGTGACCTAAATCACT
Locus tag: cur_1582
Name: cg1142 Funciton: Conserved hypothetical protein
Locus tag: cur_1581
Name: cg2803 Funciton: Conserved hypothetical protein |
|||
|
cg1142
|
Conserved hypothetical protein
|
||
|
cg2803
|
Conserved hypothetical protein
|
||
|
Position: -138
Score: 3.6 Sequence: AGTATGCCACGTCACA
Position: -69
Score: 3.4 Sequence: TGTGATCTGCCTTCCA
Locus tag: cur_0684
Name: deaD Funciton: Cold shock ATP-dependent RNA helicase |
|||
|
deaD
|
Cold shock ATP-dependent RNA helicase
|
||
|
Position: -205
Score: 3.9 Sequence: TGTGGATTTGTCCACA
Locus tag: cur_1984
Name: dnaB Funciton: Replicative DNA helicase (EC 3.6.1.-) |
|||
|
dnaB
|
Replicative DNA helicase (EC 3.6.1.-)
|
||
|
Position: -83
Score: 4 Sequence: AGTGACGCGGATCTCT
Locus tag: cur_0020
Name: qacA Funciton: Antiseptic resistance protein
Locus tag: cur_0019
Name: qacR Funciton: Drugs resistance transcriptional regulator protein QacR, TetR family |
|||
|
qacA
|
Antiseptic resistance protein
|
||
|
qacR
|
Drugs resistance transcriptional regulator protein QacR, TetR family
|
||
|
Position: -78
Score: 4.3 Sequence: AGTGACCTGCACCACT
Locus tag: cur_1339
Name: fadD5 Funciton: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) |
|||
|
fadD5
|
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
|
||
|
Position: -470
Score: 3.9 Sequence: AGTGTAACAAACCACA
Position: -468
Score: 3.7 Sequence: TGTAACAAACCACACA
Locus tag: cur_0110
Name: qacA Funciton: Antiseptic resistance protein |
|||
|
qacA
|
Antiseptic resistance protein
|
||
|
Position: -383
Score: 4 Sequence: GGTGGCGTGGATCACC
Locus tag: cur_1236
Name: ctaE Funciton: Cytochrome c oxidase polypeptide III (EC 1.9.3.1)
Locus tag: cur_1235
Name: qcrC Funciton: Ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit
Locus tag: cur_1234
Name: qcrA Funciton: Ubiquinol-cytochrome C reductase, iron-sulfur subunit (EC 1.10.2.2)
Locus tag: cur_1233
Name: qcrB Funciton: Ubiquinol cytochrome C oxidoreductase, cytochrome B subunit (EC 1.10.2.2) |
|||
|
ctaE
|
Cytochrome c oxidase polypeptide III (EC 1.9.3.1)
|
||
|
qcrC
|
Ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit
|
||
|
qcrA
|
Ubiquinol-cytochrome C reductase, iron-sulfur subunit (EC 1.10.2.2)
|
||
|
qcrB
|
Ubiquinol cytochrome C oxidoreductase, cytochrome B subunit (EC 1.10.2.2)
|
||
|
Position: -92
Score: 4.3 Sequence: TGTGTGCTTCTTCACA
Locus tag: cur_1002
Name: ctaA Funciton: Cytochrome oxidase assembly protein |
|||
|
ctaA
|
Cytochrome oxidase assembly protein
|
||
|
Position: -207
Score: 3.5 Sequence: TGTGTCTTAAATAATT
Locus tag: cur_1005
Name: mptB Funciton: Putative membrane protein
Locus tag: cur_1004
Name: CORAM0001_0942 Funciton: ABC-type multidrug transport system, ATPase component
Locus tag: cur_1003
Name: CORAM0001_0941 Funciton: ABC drug efflux pump, inner membrane subunit, DrrB family |
|||
|
mptB
|
Putative membrane protein
|
||
|
CORAM0001_0942
|
ABC-type multidrug transport system, ATPase component
|
||
|
CORAM0001_0941
|
ABC drug efflux pump, inner membrane subunit, DrrB family
|
||
|
Position: -3
Score: 4 Sequence: TGAGTGGCAGCTCACA
Locus tag: cur_0993
Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1) |
|||
|
tpiA
|
Triosephosphate isomerase (EC 5.3.1.1)
|
||
|
Position: -101
Score: 3.4 Sequence: CGTGCCCCTCGTCACC
Locus tag: cur_1672
Name: genF Funciton: Fumarylpyruvate hydrolase |
|||
|
genF
|
Fumarylpyruvate hydrolase
|
||
|
Position: -150
Score: 4.4 Sequence: GGTGAAACACGTCACA
Locus tag: cur_1567
Name: rpf1 Funciton: Resuscitation-promoting factor Rpf1 |
|||
|
rpf1
|
Resuscitation-promoting factor Rpf1
|
||
|
Position: -185
Score: 4 Sequence: TGTGATTTGTCTCTCG
Position: -38
Score: 4 Sequence: CGTGATCGAGGTCACC
Locus tag: cur_0192
Name: glcB Funciton: Malate synthase G (EC 2.3.3.9) |
|||
|
glcB
|
Malate synthase G (EC 2.3.3.9)
|
||
|
Position: -120
Score: 3.9 Sequence: TGTGATCTACGCCATG
Locus tag: cur_1688
Name: fadE3 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2)
Locus tag: cur_1687
Name: fadE4 Funciton: Probable acyl-CoA dehydrogenase (EC 1.3.99.3) |
|||
|
fadE3
|
Butyryl-CoA dehydrogenase (EC 1.3.99.2)
|
||
|
fadE4
|
Probable acyl-CoA dehydrogenase (EC 1.3.99.3)
|
||
|
Position: -53
Score: 4.1 Sequence: TGTGAGGTGATACACT
Locus tag: cur_0764
Name: leuB Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85) |
|||
|
leuB
|
3-isopropylmalate dehydrogenase (EC 1.1.1.85)
|
||
|
Position: -65
Score: 3.5 Sequence: AATTATTTAAGACACA
Locus tag: cur_1006
Name: sufR Funciton: Iron-sulfur cluster biogenesis transcriptional regulator SufR, ArsR family
Locus tag: cur_1007
Name: sufB Funciton: Iron-sulfur cluster assembly protein SufB
Locus tag: cur_1008
Name: sufD Funciton: Iron-sulfur cluster assembly protein SufD
Locus tag: cur_1009
Name: sufC Funciton: Iron-sulfur cluster assembly ATPase protein SufC
Locus tag: cur_1010
Name: sufS Funciton: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
Locus tag: cur_1011
Name: sufU Funciton: Iron-sulfur cluster assembly scaffold protein
Locus tag: cur_1012
Name: sufT Funciton: Predicted Fe-S cluster assembly protein |
|||
|
sufR
|
Iron-sulfur cluster biogenesis transcriptional regulator SufR, ArsR family
|
||
|
sufB
|
Iron-sulfur cluster assembly protein SufB
|
||
|
sufD
|
Iron-sulfur cluster assembly protein SufD
|
||
|
sufC
|
Iron-sulfur cluster assembly ATPase protein SufC
|
||
|
sufS
|
Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
|
||
|
sufU
|
Iron-sulfur cluster assembly scaffold protein
|
||
|
sufT
|
Predicted Fe-S cluster assembly protein
|
||
|
Position: -78
Score: 4.6 Sequence: TGTGACCTGAATCACG
Locus tag: cur_1749
Name: fadD10 Funciton: 4-coumarate--CoA ligase 1 (EC 6.2.1.12) |
|||
|
fadD10
|
4-coumarate--CoA ligase 1 (EC 6.2.1.12)
|
||
|
Position: -203
Score: 4.7 Sequence: TGTGATGGTAATCACA
Locus tag: cur_1522
Name: cg0952 Funciton: Putative membrane protein
Locus tag: cur_1523
Name: mctC Funciton: Monocarboxylic acid transporter |
|||
|
cg0952
|
Putative membrane protein
|
||
|
mctC
|
Monocarboxylic acid transporter
|
||
|
Position: -220
Score: 3.4 Sequence: GGTGAAGAAAAACTCT
Locus tag: cur_0173
Name: pck Funciton: Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) |
|||
|
pck
|
Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)
|
||
|
Position: -49
Score: 3.9 Sequence: TGTAAAGTGTCTCACA
Locus tag: cur_1813
Name: aldA Funciton: Aldehyde dehydrogenase (EC 1.2.1.3) |
|||
|
aldA
|
Aldehyde dehydrogenase (EC 1.2.1.3)
|
||
|
Position: -214
Score: 3.6 Sequence: TGTGACGTGCGCTACG
Position: -180
Score: 4.3 Sequence: AGTGAAGCCGATCACA
Locus tag: cur_1739
Name: pta Funciton: Phosphate acetyltransferase (EC 2.3.1.8)
Locus tag: cur_1738
Name: ackA Funciton: Acetate kinase (EC 2.7.2.1) |
|||
|
pta
|
Phosphate acetyltransferase (EC 2.3.1.8)
|
||
|
ackA
|
Acetate kinase (EC 2.7.2.1)
|
||
|
Position: -50
Score: 3.6 Sequence: TGTGATCCGAGCAACC
Locus tag: cur_1255
Name: glnA Funciton: Glutamine synthetase type I (EC 6.3.1.2) |
|||
|
glnA
|
Glutamine synthetase type I (EC 6.3.1.2)
|
||
|
Position: -1
Score: 4.3 Sequence: TGTGGCGAAGGCCACA
Locus tag: cur_1844
Name: cg3090 Funciton: Predicted permease, MFS family |
|||
|
cg3090
|
Predicted permease, MFS family
|
||
|
Position: -47
Score: 4.5 Sequence: AGTGATGCAGGACACA
Locus tag: cur_0179
Name: fadA1 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Locus tag: cur_0178
Name: fadB1 Funciton: Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) |
|||
|
fadA1
|
3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
|
||
|
fadB1
|
Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)
|
||
|
Position: -176
Score: 3.9 Sequence: TGTAATCAAGATCTCA
Position: -46
Score: 4.3 Sequence: TATGATGTACATCACG
Locus tag: cur_0800
Name: gdh Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) |
|||
|
gdh
|
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
|
||
|
Position: -268
Score: 4 Sequence: CGAGAGACAAATCACA
Position: -138
Score: 4 Sequence: AGTGGCCCATGACACA
Locus tag: cur_0191
Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30) |
|||
|
aceA
|
Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30)
|
||
|
Position: -16
Score: 4 Sequence: TGTGAGGAGGCTCATA
Locus tag: cur_0447
Name: prpD Funciton: 2-methylcitrate dehydratase (EC 4.2.1.79)
Locus tag: cur_0448
Name: prpC Funciton: 2-methylcitrate synthase (EC 2.3.3.5) |
|||
|
prpD
|
2-methylcitrate dehydratase (EC 4.2.1.79)
|
||
|
prpC
|
2-methylcitrate synthase (EC 2.3.3.5)
|
||
|
Position: -114
Score: 4.1 Sequence: GGTGACTGAGGCCACA
Position: -72
Score: 4.1 Sequence: AGAGTTCTGGGTCACA
Locus tag: cur_0606
Name: fadE6 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2) |
|||
|
fadE6
|
Butyryl-CoA dehydrogenase (EC 1.3.99.2)
|
||
|
Position: -6
Score: 3.4 Sequence: TGAGACGTGGACTACT
Locus tag: cur_1285
Name: thrC Funciton: Threonine synthase (EC 4.2.3.1) |
|||
|
thrC
|
Threonine synthase (EC 4.2.3.1)
|
||
|
Position: 30
Score: 4.3 Sequence: TGTGGCCTTCGCCACA
Locus tag: cur_1845
Name: acx Funciton: Acyl-CoA oxidase 1, peroxisomal (EC 1.3.3.6) |
|||
|
acx
|
Acyl-CoA oxidase 1, peroxisomal (EC 1.3.3.6)
|
||
|
Position: -161
Score: 4 Sequence: TGTGACCCCCAACACC
Locus tag: cur_1136
Name: fabG2 Funciton: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
Locus tag: cur_1137
Name: fas Funciton: Acyl dehydratase |
|||
|
fabG2
|
3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
|
||
|
fas
|
Acyl dehydratase
|
||
|
Position: -263
Score: 4 Sequence: GGTGAATGTGATCACA
Locus tag: cur_0710
Name: atpB Funciton: ATP synthase A chain (EC 3.6.3.14)
Locus tag: cur_0711
Name: atpE Funciton: ATP synthase C chain (EC 3.6.3.14)
Locus tag: cur_0712
Name: atpF Funciton: ATP synthase B chain (EC 3.6.3.14)
Locus tag: cur_0713
Name: atpH Funciton: ATP synthase delta chain (EC 3.6.3.14)
Locus tag: cur_0714
Name: atpA Funciton: ATP synthase alpha chain (EC 3.6.3.14)
Locus tag: cur_0715
Name: atpG Funciton: ATP synthase gamma chain (EC 3.6.3.14)
Locus tag: cur_0716
Name: atpD Funciton: ATP synthase beta chain (EC 3.6.3.14)
Locus tag: cur_0717
Name: atpC Funciton: ATP synthase epsilon chain (EC 3.6.3.14) |
|||
|
atpB
|
ATP synthase A chain (EC 3.6.3.14)
|
||
|
atpE
|
ATP synthase C chain (EC 3.6.3.14)
|
||
|
atpF
|
ATP synthase B chain (EC 3.6.3.14)
|
||
|
atpH
|
ATP synthase delta chain (EC 3.6.3.14)
|
||
|
atpA
|
ATP synthase alpha chain (EC 3.6.3.14)
|
||
|
atpG
|
ATP synthase gamma chain (EC 3.6.3.14)
|
||
|
atpD
|
ATP synthase beta chain (EC 3.6.3.14)
|
||
|
atpC
|
ATP synthase epsilon chain (EC 3.6.3.14)
|
||
|
Position: -29
Score: 3.9 Sequence: TGTGAATATTGATACC
Locus tag: cur_1859
Name: cg0360 Funciton: Predicted phosphatase |
|||
|
cg0360
|
Predicted phosphatase
|
||
|
Position: -49
Score: 4.5 Sequence: TGAGACCCGCATCACA
Locus tag: cur_0212
Name: fadD6 Funciton: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) |
|||
|
fadD6
|
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
|
||
|
Position: -317
Score: 4.1 Sequence: TGTGGTTCAGTTCTCA
Position: -238
Score: 3.8 Sequence: TGTCGCGTAGCTCACA
Locus tag: cur_1557
Name: gltA Funciton: Citrate synthase (EC 2.3.3.1) |
|||
|
gltA
|
Citrate synthase (EC 2.3.3.1)
|
||
|
Position: -401
Score: 4.1 Sequence: TGTTACGGGGGTCACA
Position: -191
Score: 4.5 Sequence: TGTGATGCGCCCCACA
Locus tag: cur_1872
Name: pbp1B Funciton: Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) |
|||
|
pbp1B
|
Multimodular transpeptidase-transglycosylase (EC 2.4.1.129)
|
||
|
Position: -140
Score: 4 Sequence: TGTTAGTATCATCACA
Locus tag: cur_0753
Name: ilvB Funciton: Acetolactate synthase, large subunit (EC 2.2.1.6)
Locus tag: cur_0754
Name: ilvN Funciton: Acetolactate synthase, small subunit (EC 2.2.1.6)
Locus tag: cur_0755
Name: ilvC Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86) |
|||
|
ilvB
|
Acetolactate synthase, large subunit (EC 2.2.1.6)
|
||
|
ilvN
|
Acetolactate synthase, small subunit (EC 2.2.1.6)
|
||
|
ilvC
|
Ketol-acid reductoisomerase (EC 1.1.1.86)
|
||
|
Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |