Regulon of GlxR in Corynebacterium kroppenstedtii DSM 44385
| Regulator type: | Transcription factor |
| TF locus tag: | ckrop_2008 |
| Regulator family: | CRP |
| Regulation mode: | repressor (activator) |
| Biological process: | Energy metabolism; Carbohydrate metabolism |
| Effector: | Cyclic 3',5'-AMP |
| Regulog: | GlxR - Corynebacteriaceae |
| Statistics of regulated genes: | |
| - Genes | 68 |
| - Operons | 47 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Corynebacteriaceae
- By TF family - CRP
- By effector - Cyclic 3',5'-AMP
- By pathway - Energy metabolism
- By pathway - Carbohydrate metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -252
Score: 4.4 Sequence: TGTGAAGTGAGTCTCA
Position: -151
Score: 3.8 Sequence: TGTGATGTAGTCGACA
Position: -123
Score: 3.7 Sequence: TGTGAATAGACTTACA
Locus tag: ckrop_2012
Name: whiB4 Funciton: Predicted transcriptional regulator, WhiB family |
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whiB4
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Predicted transcriptional regulator, WhiB family
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Position: 12
Score: 3.8 Sequence: AGTGACGTTGATCTCG
Locus tag: ckrop_0939
Name: acnR Funciton: Aconitase gene transcriptional regulator AcnR, TetR family |
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acnR
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Aconitase gene transcriptional regulator AcnR, TetR family
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Position: -242
Score: 3.2 Sequence: GGTGAATAAGGCCCCA
Locus tag: ckrop_0938
Name: acn Funciton: Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99) |
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acn
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Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
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Position: -332
Score: 3.8 Sequence: TGTGAGATTCGTCAAA
Locus tag: ckrop_2079
Name: dnaB Funciton: Replicative DNA helicase (EC 3.6.1.-) |
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dnaB
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Replicative DNA helicase (EC 3.6.1.-)
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Position: -272
Score: 3.8 Sequence: TGTCGTCCACGTCACA
Position: -196
Score: 3.8 Sequence: AGTGAGGTTCTACACT
Locus tag: ckrop_0444
Name: gltA Funciton: Citrate synthase (EC 2.3.3.1) |
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gltA
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Citrate synthase (EC 2.3.3.1)
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Position: -199
Score: 4.1 Sequence: TGTGTGTTTGCTCACT
Locus tag: ckrop_1407
Name: serB Funciton: Phosphoserine phosphatase (EC 3.1.3.3)
Locus tag: ckrop_1406
Name: cg2778 Funciton: Putative hydrolase |
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serB
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Phosphoserine phosphatase (EC 3.1.3.3)
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cg2778
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Putative hydrolase
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Position: -261
Score: 3.9 Sequence: CGTGACCAACCGCACA
Position: -98
Score: 3.9 Sequence: TGTGAGGTGCGATACA
Locus tag: ckrop_2008
Name: glxR Funciton: Carbohydrate and energy metabolism global transcriptional regulator GlxR, Crp family |
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glxR
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Carbohydrate and energy metabolism global transcriptional regulator GlxR, Crp family
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Position: -265
Score: 4.2 Sequence: TATGTTTCAGATCACA
Position: -212
Score: 3.9 Sequence: TATGATCTAGATAACT
Position: -190
Score: 4.4 Sequence: TGTGGTTCGCGTCACT
Position: -168
Score: 4.2 Sequence: TGTTTTGTGCGTCACA
Position: -100
Score: 3.7 Sequence: AGTGTTTCGCCGCACA
Locus tag: ckrop_1956
Name: glcB Funciton: Malate synthase G (EC 2.3.3.9) |
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glcB
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Malate synthase G (EC 2.3.3.9)
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Position: 36
Score: 3.9 Sequence: AGTGACAATCAGCACA
Locus tag: ckrop_0533
Name: echA3 Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) |
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echA3
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3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
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Position: -387
Score: 4 Sequence: AGTGATTCGGGCCACC
Locus tag: ckrop_1726
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
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metE
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5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
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Position: -278
Score: 4.5 Sequence: TGTGACTTTTAACACA
Locus tag: ckrop_1487
Name: whiB1 Funciton: Predicted transcriptional regulator, WhiB family |
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whiB1
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Predicted transcriptional regulator, WhiB family
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Position: -214
Score: 3.8 Sequence: AGTGTAGAACCTCACT
Position: -138
Score: 3.8 Sequence: TGTGACGTGGACGACA
Locus tag: ckrop_0443
Name: serC Funciton: Phosphoserine aminotransferase (EC 2.6.1.52) |
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serC
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Phosphoserine aminotransferase (EC 2.6.1.52)
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Position: -173
Score: 3.5 Sequence: AGTGTTGTTAGCCATA
Locus tag: ckrop_0449
Name: accDA Funciton: Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) / Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2) |
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accDA
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Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) / Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2)
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Position: -224
Score: 4.4 Sequence: TGTGTCCTCTATCACA
Locus tag: ckrop_0524
Name: rpf2 Funciton: Cell wall-binding protein
Locus tag: ckrop_0525
Name: ksgA Funciton: Dimethyladenosine transferase (EC 2.1.1.-)
Locus tag: ckrop_0526
Name: ispE Funciton: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)
Locus tag: ckrop_0527
Name: cg1040 Funciton: Predicted ABC transporter, ATP-binding protein |
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rpf2
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Cell wall-binding protein
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ksgA
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Dimethyladenosine transferase (EC 2.1.1.-)
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ispE
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4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)
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cg1040
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Predicted ABC transporter, ATP-binding protein
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Position: -28
Score: 3.5 Sequence: TATGAGATAGGTCATT
Locus tag: ckrop_0568
Name: coaA Funciton: Pantothenate kinase (EC 2.7.1.33) |
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coaA
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Pantothenate kinase (EC 2.7.1.33)
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Position: -140
Score: 4.1 Sequence: TATGACCTACACCACT
Position: -15
Score: 3.8 Sequence: TGGGACTTACATAACA
Locus tag: ckrop_0578
Name: fum Funciton: Fumarate hydratase class II (EC 4.2.1.2) |
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fum
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Fumarate hydratase class II (EC 4.2.1.2)
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Position: -162
Score: 3.9 Sequence: GGTGACCCAGGCCACC
Locus tag: ckrop_1939
Name: cg3286 Funciton: conserved hypothetical protein
Locus tag: ckrop_1938
Name: copO Funciton: Multicopper oxidase, secreted |
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cg3286
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conserved hypothetical protein
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copO
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Multicopper oxidase, secreted
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Position: -96
Score: 4.4 Sequence: TGAGATTCATATCACT
Locus tag: ckrop_0819
Name: fabG2 Funciton: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
Locus tag: ckrop_0818
Name: fas Funciton: Acyl dehydratase |
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fabG2
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3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
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fas
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Acyl dehydratase
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Position: -30
Score: 4.4 Sequence: AGTGATATGAATCTCA
Locus tag: ckrop_0820
Name: fadA2 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9) |
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fadA2
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3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
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Position: -44
Score: 3.9 Sequence: AGTAGCGTAGGTCACA
Locus tag: ckrop_1328
Name: fadD5 Funciton: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) |
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fadD5
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Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
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Position: -109
Score: 4.4 Sequence: TGTGGCGAGCCTCACA
Locus tag: ckrop_0817
Name: ptsG Funciton: Glucose-specific PTS system, IIABC component |
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ptsG
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Glucose-specific PTS system, IIABC component
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Position: -81
Score: 3.8 Sequence: TGTGATCCGACATACA
Locus tag: ckrop_0879
Name: ndh Funciton: NADH dehydrogenase (EC 1.6.99.3) |
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ndh
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NADH dehydrogenase (EC 1.6.99.3)
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Position: -144
Score: 3.9 Sequence: AGTGTTGTTTGTCTCA
Locus tag: ckrop_0969
Name: gap Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
Locus tag: ckrop_0968
Name: pgk Funciton: Phosphoglycerate kinase (EC 2.7.2.3)
Locus tag: ckrop_0967
Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1) |
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gap
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NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
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pgk
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Phosphoglycerate kinase (EC 2.7.2.3)
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tpiA
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Triosephosphate isomerase (EC 5.3.1.1)
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Position: 5
Score: 3.6 Sequence: CGTGAAGCTTGTCACC
Locus tag: ckrop_1188
Name: glnK Funciton: Nitrogen regulatory protein PII
Locus tag: ckrop_1187
Name: glnD Funciton: [Protein-PII] Uridylyltransferase |
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glnK
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Nitrogen regulatory protein PII
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glnD
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[Protein-PII] Uridylyltransferase
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Position: -251
Score: 3.8 Sequence: TGGGTTTTATTTCACA
Locus tag: ckrop_1189
Name: amtB Funciton: ammonium transporter NrgA |
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amtB
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ammonium transporter NrgA
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Position: -180
Score: 3.8 Sequence: TGTGGCACATAGCACT
Locus tag: ckrop_1094
Name: ptsH Funciton: Phosphocarrier protein of PTS system |
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ptsH
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Phosphocarrier protein of PTS system
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Position: -247
Score: 4.1 Sequence: AGTGGGAAAAGTCACA
Locus tag: ckrop_1090
Name: sugR Funciton: Sugar metabolism transcriptional regulator SugR, DeoR family
Locus tag: ckrop_1091
Name: pfkB Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: ckrop_1092
Name: ptsF Funciton: Fructose-specific PTS, IIABC component |
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sugR
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Sugar metabolism transcriptional regulator SugR, DeoR family
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pfkB
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1-phosphofructokinase (EC 2.7.1.56)
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ptsF
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Fructose-specific PTS, IIABC component
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Position: -89
Score: 4.1 Sequence: TGTGACTTTTCCCACT
Locus tag: ckrop_1089
Name: ptsI Funciton: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) |
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ptsI
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Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
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Position: -218
Score: 4.4 Sequence: AGTGTTCTTAATCACA
Locus tag: ckrop_0433
Name: rpf1 Funciton: Resuscitation-promoting factor Rpf1 |
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rpf1
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Resuscitation-promoting factor Rpf1
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Position: -101
Score: 4.2 Sequence: TGTGATACCGATCACG
Locus tag: ckrop_1642
Name: fadE3 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2)
Locus tag: ckrop_1641
Name: fadE4 Funciton: Probable acyl-CoA dehydrogenase (EC 1.3.99.3) |
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fadE3
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Butyryl-CoA dehydrogenase (EC 1.3.99.2)
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fadE4
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Probable acyl-CoA dehydrogenase (EC 1.3.99.3)
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Position: -174
Score: 3.9 Sequence: GGTGGCCTGGGTCACC
Locus tag: ckrop_1940
Name: copR Funciton: Copper homeostasis transcriptional regulator CopR, OmpR family
Locus tag: ckrop_1941
Name: copS Funciton: Copper homeostasis regulatory system, sensor kinase
Locus tag: ckrop_1942
Name: copZ Funciton: Copper insertion chaperone and transporter component
Locus tag: ckrop_1943
Name: copB Funciton: Copper-translocating P-type ATPase (EC 3.6.3.4) |
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copR
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Copper homeostasis transcriptional regulator CopR, OmpR family
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copS
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Copper homeostasis regulatory system, sensor kinase
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copZ
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Copper insertion chaperone and transporter component
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copB
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Copper-translocating P-type ATPase (EC 3.6.3.4)
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Position: -22
Score: 3.4 Sequence: TGTGAGAAAGGTATCT
Locus tag: ckrop_1234
Name: leuB Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85) |
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leuB
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3-isopropylmalate dehydrogenase (EC 1.1.1.85)
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Position: -87
Score: 3.5 Sequence: TGTGACGACTATAACC
Locus tag: ckrop_1677
Name: famR Funciton: Fatty acids metabolism transcriptional regulator FamR, MarR family |
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famR
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Fatty acids metabolism transcriptional regulator FamR, MarR family
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Position: -139
Score: 3.5 Sequence: TGTGAAATCCGTCGCT
Locus tag: ckrop_0253
Name: pck Funciton: Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) |
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pck
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Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)
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Position: -126
Score: 3.9 Sequence: TGTGCCAAACCCCACA
Position: -97
Score: 3.4 Sequence: GGTGGTTCAGCACACG
Locus tag: ckrop_1687
Name: pta Funciton: Phosphate acetyltransferase (EC 2.3.1.8)
Locus tag: ckrop_1686
Name: ackA Funciton: Acetate kinase (EC 2.7.2.1) |
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pta
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Phosphate acetyltransferase (EC 2.3.1.8)
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ackA
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Acetate kinase (EC 2.7.2.1)
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Position: -257
Score: 3.5 Sequence: TGTGAGGATGCTGACA
Locus tag: ckrop_0708
Name: ctaC Funciton: Cytochrome c oxidase polypeptide II (EC 1.9.3.1)
Locus tag: ckrop_0709
Name: ctaF Funciton: Cytochrome c oxidase polypeptide IV (EC 1.9.3.1) |
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ctaC
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Cytochrome c oxidase polypeptide II (EC 1.9.3.1)
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ctaF
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Cytochrome c oxidase polypeptide IV (EC 1.9.3.1)
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Position: -234
Score: 4.4 Sequence: TGTTATTCGCGTCACA
Locus tag: ckrop_0707
Name: ltsA Funciton: Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) |
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ltsA
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Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)
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Position: -105
Score: 3.6 Sequence: CATGATCCATACCACA
Locus tag: ckrop_1972
Name: cg3090 Funciton: Predicted permease, MFS family |
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cg3090
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Predicted permease, MFS family
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Position: -132
Score: 4.4 Sequence: AGTGACTCATAACACA
Locus tag: ckrop_0258
Name: fadA1 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Locus tag: ckrop_0257
Name: fadB1 Funciton: Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) |
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fadA1
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3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
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fadB1
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Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)
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Position: 16
Score: 4.2 Sequence: TGAGGGATAAGTCACA
Locus tag: ckrop_0600
Name: gdh Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) |
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gdh
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NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
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Position: -256
Score: 4.2 Sequence: TGTGATCTGAAACATA
Locus tag: ckrop_1958
Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30) |
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aceA
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Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30)
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Position: -128
Score: 3.8 Sequence: TGTGACATGGGTTACG
Locus tag: ckrop_0571
Name: fadE6 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2) |
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fadE6
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Butyryl-CoA dehydrogenase (EC 1.3.99.2)
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Position: -1
Score: 3.8 Sequence: GGTGAAATACATCTCC
Locus tag: ckrop_0694
Name: thrC Funciton: Threonine synthase (EC 4.2.3.1) |
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thrC
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Threonine synthase (EC 4.2.3.1)
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Position: -82
Score: 4.3 Sequence: AGTGATGTGTATCACG
Locus tag: ckrop_1953
Name: sdhC Funciton: Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1)
Locus tag: ckrop_1952
Name: sdhA Funciton: Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1)
Locus tag: ckrop_1951
Name: sdhB Funciton: Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1)
Locus tag: ckrop_1950
Name: cg0448 Funciton: Conserved hypothetical protein |
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sdhC
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Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1)
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sdhA
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Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1)
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sdhB
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Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1)
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cg0448
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Conserved hypothetical protein
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Position: -205
Score: 4.1 Sequence: TGAGAGAAAGTTCACA
Locus tag: ckrop_0422
Name: ramA Funciton: Acetate metabolism transcriptional regulator RamA, LuxR family |
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ramA
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Acetate metabolism transcriptional regulator RamA, LuxR family
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Position: -263
Score: 4.1 Sequence: TGTTAGGTAGGTCTCA
Locus tag: ckrop_0693
Name: pqo Funciton: Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2) |
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pqo
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Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2)
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Position: -144
Score: 3.8 Sequence: TGTCGACTACATCACA
Position: -43
Score: 4.4 Sequence: TGAGACTCACTTCACA
Locus tag: ckrop_2013
Name: pbp1B Funciton: Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) |
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pbp1B
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Multimodular transpeptidase-transglycosylase (EC 2.4.1.129)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |