Regulon of GlxR in Corynebacterium kroppenstedtii DSM 44385

Properties
Regulator type:	Transcription factor
TF locus tag:	ckrop_2008
Regulator family:	CRP
Regulation mode:	repressor (activator)
Biological process:	Energy metabolism; Carbohydrate metabolism
Effector:	Cyclic 3',5'-AMP
Regulog:	GlxR - Corynebacteriaceae
Statistics of regulated genes:
- Genes	68
- Operons	47
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 562 sites [see more]

Member of regulog collections

By taxonomy - Corynebacteriaceae
By TF family - CRP
By effector - Cyclic 3',5'-AMP
By pathway - Energy metabolism
By pathway - Carbohydrate metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -252 Score: 4.4 Sequence: TGTGAAGTGAGTCTCA Position: -151 Score: 3.8 Sequence: TGTGATGTAGTCGACA Position: -123 Score: 3.7 Sequence: TGTGAATAGACTTACA Locus tag: ckrop_2012 Name: whiB4 Funciton: Predicted transcriptional regulator, WhiB family
	ckrop_2012	whiB4	Predicted transcriptional regulator, WhiB family
Position: 12 Score: 3.8 Sequence: AGTGACGTTGATCTCG Locus tag: ckrop_0939 Name: acnR Funciton: Aconitase gene transcriptional regulator AcnR, TetR family
	ckrop_0939	acnR	Aconitase gene transcriptional regulator AcnR, TetR family
Position: -242 Score: 3.2 Sequence: GGTGAATAAGGCCCCA Locus tag: ckrop_0938 Name: acn Funciton: Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
	ckrop_0938	acn	Aconitate hydratase (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
Position: -332 Score: 3.8 Sequence: TGTGAGATTCGTCAAA Locus tag: ckrop_2079 Name: dnaB Funciton: Replicative DNA helicase (EC 3.6.1.-)
	ckrop_2079	dnaB	Replicative DNA helicase (EC 3.6.1.-)
Position: -272 Score: 3.8 Sequence: TGTCGTCCACGTCACA Position: -196 Score: 3.8 Sequence: AGTGAGGTTCTACACT Locus tag: ckrop_0444 Name: gltA Funciton: Citrate synthase (EC 2.3.3.1)
	ckrop_0444	gltA	Citrate synthase (EC 2.3.3.1)
Position: -199 Score: 4.1 Sequence: TGTGTGTTTGCTCACT Locus tag: ckrop_1407 Name: serB Funciton: Phosphoserine phosphatase (EC 3.1.3.3) Locus tag: ckrop_1406 Name: cg2778 Funciton: Putative hydrolase
	ckrop_1407	serB	Phosphoserine phosphatase (EC 3.1.3.3)
	ckrop_1406	cg2778	Putative hydrolase
Position: -261 Score: 3.9 Sequence: CGTGACCAACCGCACA Position: -98 Score: 3.9 Sequence: TGTGAGGTGCGATACA Locus tag: ckrop_2008 Name: glxR Funciton: Carbohydrate and energy metabolism global transcriptional regulator GlxR, Crp family
	ckrop_2008	glxR	Carbohydrate and energy metabolism global transcriptional regulator GlxR, Crp family
Position: -265 Score: 4.2 Sequence: TATGTTTCAGATCACA Position: -212 Score: 3.9 Sequence: TATGATCTAGATAACT Position: -190 Score: 4.4 Sequence: TGTGGTTCGCGTCACT Position: -168 Score: 4.2 Sequence: TGTTTTGTGCGTCACA Position: -100 Score: 3.7 Sequence: AGTGTTTCGCCGCACA Locus tag: ckrop_1956 Name: glcB Funciton: Malate synthase G (EC 2.3.3.9)
	ckrop_1956	glcB	Malate synthase G (EC 2.3.3.9)
Position: 36 Score: 3.9 Sequence: AGTGACAATCAGCACA Locus tag: ckrop_0533 Name: echA3 Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
	ckrop_0533	echA3	3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Position: -387 Score: 4 Sequence: AGTGATTCGGGCCACC Locus tag: ckrop_1726 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	ckrop_1726	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -278 Score: 4.5 Sequence: TGTGACTTTTAACACA Locus tag: ckrop_1487 Name: whiB1 Funciton: Predicted transcriptional regulator, WhiB family
	ckrop_1487	whiB1	Predicted transcriptional regulator, WhiB family
Position: -214 Score: 3.8 Sequence: AGTGTAGAACCTCACT Position: -138 Score: 3.8 Sequence: TGTGACGTGGACGACA Locus tag: ckrop_0443 Name: serC Funciton: Phosphoserine aminotransferase (EC 2.6.1.52)
	ckrop_0443	serC	Phosphoserine aminotransferase (EC 2.6.1.52)
Position: -173 Score: 3.5 Sequence: AGTGTTGTTAGCCATA Locus tag: ckrop_0449 Name: accDA Funciton: Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) / Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2)
	ckrop_0449	accDA	Acetyl-coenzyme A carboxyl transferase alpha chain (EC 6.4.1.2) / Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2)
Position: -224 Score: 4.4 Sequence: TGTGTCCTCTATCACA Locus tag: ckrop_0524 Name: rpf2 Funciton: Cell wall-binding protein Locus tag: ckrop_0525 Name: ksgA Funciton: Dimethyladenosine transferase (EC 2.1.1.-) Locus tag: ckrop_0526 Name: ispE Funciton: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148) Locus tag: ckrop_0527 Name: cg1040 Funciton: Predicted ABC transporter, ATP-binding protein
	ckrop_0524	rpf2	Cell wall-binding protein
	ckrop_0525	ksgA	Dimethyladenosine transferase (EC 2.1.1.-)
	ckrop_0526	ispE	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)
	ckrop_0527	cg1040	Predicted ABC transporter, ATP-binding protein
Position: -28 Score: 3.5 Sequence: TATGAGATAGGTCATT Locus tag: ckrop_0568 Name: coaA Funciton: Pantothenate kinase (EC 2.7.1.33)
	ckrop_0568	coaA	Pantothenate kinase (EC 2.7.1.33)
Position: -140 Score: 4.1 Sequence: TATGACCTACACCACT Position: -15 Score: 3.8 Sequence: TGGGACTTACATAACA Locus tag: ckrop_0578 Name: fum Funciton: Fumarate hydratase class II (EC 4.2.1.2)
	ckrop_0578	fum	Fumarate hydratase class II (EC 4.2.1.2)
Position: -162 Score: 3.9 Sequence: GGTGACCCAGGCCACC Locus tag: ckrop_1939 Name: cg3286 Funciton: conserved hypothetical protein Locus tag: ckrop_1938 Name: copO Funciton: Multicopper oxidase, secreted
	ckrop_1939	cg3286	conserved hypothetical protein
	ckrop_1938	copO	Multicopper oxidase, secreted
Position: -96 Score: 4.4 Sequence: TGAGATTCATATCACT Locus tag: ckrop_0819 Name: fabG2 Funciton: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) Locus tag: ckrop_0818 Name: fas Funciton: Acyl dehydratase
	ckrop_0819	fabG2	3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
	ckrop_0818	fas	Acyl dehydratase
Position: -30 Score: 4.4 Sequence: AGTGATATGAATCTCA Locus tag: ckrop_0820 Name: fadA2 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
	ckrop_0820	fadA2	3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Position: -44 Score: 3.9 Sequence: AGTAGCGTAGGTCACA Locus tag: ckrop_1328 Name: fadD5 Funciton: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
	ckrop_1328	fadD5	Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
Position: -109 Score: 4.4 Sequence: TGTGGCGAGCCTCACA Locus tag: ckrop_0817 Name: ptsG Funciton: Glucose-specific PTS system, IIABC component
	ckrop_0817	ptsG	Glucose-specific PTS system, IIABC component
Position: -81 Score: 3.8 Sequence: TGTGATCCGACATACA Locus tag: ckrop_0879 Name: ndh Funciton: NADH dehydrogenase (EC 1.6.99.3)
	ckrop_0879	ndh	NADH dehydrogenase (EC 1.6.99.3)
Position: -144 Score: 3.9 Sequence: AGTGTTGTTTGTCTCA Locus tag: ckrop_0969 Name: gap Funciton: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) Locus tag: ckrop_0968 Name: pgk Funciton: Phosphoglycerate kinase (EC 2.7.2.3) Locus tag: ckrop_0967 Name: tpiA Funciton: Triosephosphate isomerase (EC 5.3.1.1)
	ckrop_0969	gap	NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
	ckrop_0968	pgk	Phosphoglycerate kinase (EC 2.7.2.3)
	ckrop_0967	tpiA	Triosephosphate isomerase (EC 5.3.1.1)
Position: 5 Score: 3.6 Sequence: CGTGAAGCTTGTCACC Locus tag: ckrop_1188 Name: glnK Funciton: Nitrogen regulatory protein PII Locus tag: ckrop_1187 Name: glnD Funciton: [Protein-PII] Uridylyltransferase
	ckrop_1188	glnK	Nitrogen regulatory protein PII
	ckrop_1187	glnD	[Protein-PII] Uridylyltransferase
Position: -251 Score: 3.8 Sequence: TGGGTTTTATTTCACA Locus tag: ckrop_1189 Name: amtB Funciton: ammonium transporter NrgA
	ckrop_1189	amtB	ammonium transporter NrgA
Position: -180 Score: 3.8 Sequence: TGTGGCACATAGCACT Locus tag: ckrop_1094 Name: ptsH Funciton: Phosphocarrier protein of PTS system
	ckrop_1094	ptsH	Phosphocarrier protein of PTS system
Position: -247 Score: 4.1 Sequence: AGTGGGAAAAGTCACA Locus tag: ckrop_1090 Name: sugR Funciton: Sugar metabolism transcriptional regulator SugR, DeoR family Locus tag: ckrop_1091 Name: pfkB Funciton: 1-phosphofructokinase (EC 2.7.1.56) Locus tag: ckrop_1092 Name: ptsF Funciton: Fructose-specific PTS, IIABC component
	ckrop_1090	sugR	Sugar metabolism transcriptional regulator SugR, DeoR family
	ckrop_1091	pfkB	1-phosphofructokinase (EC 2.7.1.56)
	ckrop_1092	ptsF	Fructose-specific PTS, IIABC component
Position: -89 Score: 4.1 Sequence: TGTGACTTTTCCCACT Locus tag: ckrop_1089 Name: ptsI Funciton: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
	ckrop_1089	ptsI	Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9)
Position: -218 Score: 4.4 Sequence: AGTGTTCTTAATCACA Locus tag: ckrop_0433 Name: rpf1 Funciton: Resuscitation-promoting factor Rpf1
	ckrop_0433	rpf1	Resuscitation-promoting factor Rpf1
Position: -101 Score: 4.2 Sequence: TGTGATACCGATCACG Locus tag: ckrop_1642 Name: fadE3 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2) Locus tag: ckrop_1641 Name: fadE4 Funciton: Probable acyl-CoA dehydrogenase (EC 1.3.99.3)
	ckrop_1642	fadE3	Butyryl-CoA dehydrogenase (EC 1.3.99.2)
	ckrop_1641	fadE4	Probable acyl-CoA dehydrogenase (EC 1.3.99.3)
Position: -174 Score: 3.9 Sequence: GGTGGCCTGGGTCACC Locus tag: ckrop_1940 Name: copR Funciton: Copper homeostasis transcriptional regulator CopR, OmpR family Locus tag: ckrop_1941 Name: copS Funciton: Copper homeostasis regulatory system, sensor kinase Locus tag: ckrop_1942 Name: copZ Funciton: Copper insertion chaperone and transporter component Locus tag: ckrop_1943 Name: copB Funciton: Copper-translocating P-type ATPase (EC 3.6.3.4)
	ckrop_1940	copR	Copper homeostasis transcriptional regulator CopR, OmpR family
	ckrop_1941	copS	Copper homeostasis regulatory system, sensor kinase
	ckrop_1942	copZ	Copper insertion chaperone and transporter component
	ckrop_1943	copB	Copper-translocating P-type ATPase (EC 3.6.3.4)
Position: -22 Score: 3.4 Sequence: TGTGAGAAAGGTATCT Locus tag: ckrop_1234 Name: leuB Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
	ckrop_1234	leuB	3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Position: -87 Score: 3.5 Sequence: TGTGACGACTATAACC Locus tag: ckrop_1677 Name: famR Funciton: Fatty acids metabolism transcriptional regulator FamR, MarR family
	ckrop_1677	famR	Fatty acids metabolism transcriptional regulator FamR, MarR family
Position: -139 Score: 3.5 Sequence: TGTGAAATCCGTCGCT Locus tag: ckrop_0253 Name: pck Funciton: Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)
	ckrop_0253	pck	Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)
Position: -126 Score: 3.9 Sequence: TGTGCCAAACCCCACA Position: -97 Score: 3.4 Sequence: GGTGGTTCAGCACACG Locus tag: ckrop_1687 Name: pta Funciton: Phosphate acetyltransferase (EC 2.3.1.8) Locus tag: ckrop_1686 Name: ackA Funciton: Acetate kinase (EC 2.7.2.1)
	ckrop_1687	pta	Phosphate acetyltransferase (EC 2.3.1.8)
	ckrop_1686	ackA	Acetate kinase (EC 2.7.2.1)
Position: -257 Score: 3.5 Sequence: TGTGAGGATGCTGACA Locus tag: ckrop_0708 Name: ctaC Funciton: Cytochrome c oxidase polypeptide II (EC 1.9.3.1) Locus tag: ckrop_0709 Name: ctaF Funciton: Cytochrome c oxidase polypeptide IV (EC 1.9.3.1)
	ckrop_0708	ctaC	Cytochrome c oxidase polypeptide II (EC 1.9.3.1)
	ckrop_0709	ctaF	Cytochrome c oxidase polypeptide IV (EC 1.9.3.1)
Position: -234 Score: 4.4 Sequence: TGTTATTCGCGTCACA Locus tag: ckrop_0707 Name: ltsA Funciton: Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)
	ckrop_0707	ltsA	Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)
Position: -105 Score: 3.6 Sequence: CATGATCCATACCACA Locus tag: ckrop_1972 Name: cg3090 Funciton: Predicted permease, MFS family
	ckrop_1972	cg3090	Predicted permease, MFS family
Position: -132 Score: 4.4 Sequence: AGTGACTCATAACACA Locus tag: ckrop_0258 Name: fadA1 Funciton: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9) Locus tag: ckrop_0257 Name: fadB1 Funciton: Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)
	ckrop_0258	fadA1	3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
	ckrop_0257	fadB1	Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)
Position: 16 Score: 4.2 Sequence: TGAGGGATAAGTCACA Locus tag: ckrop_0600 Name: gdh Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
	ckrop_0600	gdh	NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
Position: -256 Score: 4.2 Sequence: TGTGATCTGAAACATA Locus tag: ckrop_1958 Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30)
	ckrop_1958	aceA	Isocitrate lyase (EC 4.1.3.1) / Methylisocitrate lyase (EC 4.1.3.30)
Position: -128 Score: 3.8 Sequence: TGTGACATGGGTTACG Locus tag: ckrop_0571 Name: fadE6 Funciton: Butyryl-CoA dehydrogenase (EC 1.3.99.2)
	ckrop_0571	fadE6	Butyryl-CoA dehydrogenase (EC 1.3.99.2)
Position: -1 Score: 3.8 Sequence: GGTGAAATACATCTCC Locus tag: ckrop_0694 Name: thrC Funciton: Threonine synthase (EC 4.2.3.1)
	ckrop_0694	thrC	Threonine synthase (EC 4.2.3.1)
Position: -82 Score: 4.3 Sequence: AGTGATGTGTATCACG Locus tag: ckrop_1953 Name: sdhC Funciton: Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1) Locus tag: ckrop_1952 Name: sdhA Funciton: Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1) Locus tag: ckrop_1951 Name: sdhB Funciton: Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1) Locus tag: ckrop_1950 Name: cg0448 Funciton: Conserved hypothetical protein
	ckrop_1953	sdhC	Succinate dehydrogenase, cytochrome b subunit (EC 1.3.99.1)
	ckrop_1952	sdhA	Succinate dehydrogenase, flavoprotein subunit (EC 1.3.99.1)
	ckrop_1951	sdhB	Succinate dehydrogenase, iron-sulfur cluster subunit (EC 1.3.99.1)
	ckrop_1950	cg0448	Conserved hypothetical protein
Position: -205 Score: 4.1 Sequence: TGAGAGAAAGTTCACA Locus tag: ckrop_0422 Name: ramA Funciton: Acetate metabolism transcriptional regulator RamA, LuxR family
	ckrop_0422	ramA	Acetate metabolism transcriptional regulator RamA, LuxR family
Position: -263 Score: 4.1 Sequence: TGTTAGGTAGGTCTCA Locus tag: ckrop_0693 Name: pqo Funciton: Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2)
	ckrop_0693	pqo	Pyruvate oxidase [ubiquinone, cytochrome] (EC 1.2.2.2)
Position: -144 Score: 3.8 Sequence: TGTCGACTACATCACA Position: -43 Score: 4.4 Sequence: TGAGACTCACTTCACA Locus tag: ckrop_2013 Name: pbp1B Funciton: Multimodular transpeptidase-transglycosylase (EC 2.4.1.129)
	ckrop_2013	pbp1B	Multimodular transpeptidase-transglycosylase (EC 2.4.1.129)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of GlxR in Corynebacterium kroppenstedtii DSM 44385

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --