Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Paracoccus denitrificans PD1222

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Rhodobacterales
Under regulation:
- Genes 39
- Operons 10
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -241
Score: 133.6
Sequence: TAACATATGCGTGTA...
Locus tag: Pden_2524
Name: cbtB
Funciton: Putative cobalt transporter, subunit CbtB
Locus tag: Pden_2525
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: Pden_2526
Name: Pden_2526
Funciton: hypothetical protein
Locus tag: Pden_2527
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
cbtB
Putative cobalt transporter, subunit CbtB
cbtA
Predicted cobalt transporter CbtA
Pden_2526
hypothetical protein
bluB
Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family

Position: -414
Score: 119
Sequence: CCCTATATGTAGGCA...
Locus tag: Pden_2989
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: Pden_2988
Name: Pden_2988
Funciton: hypothetical protein
Locus tag: Pden_2987
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Pden_2988
hypothetical protein
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

Position: -408
Score: 127.9
Sequence: CTACACGGTCGGGTG...
Locus tag: Pden_4827
Name: btuB
Funciton: Outer membrane (iron.B12.siderophore.hemin) receptor
Locus tag: Pden_4828
Name: btuD
Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
Locus tag: Pden_4829
Name: btuF
Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
Locus tag: Pden_4830
Name: btuC
Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component
btuB
Outer membrane (iron.B12.siderophore.hemin) receptor
btuD
ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
btuF
ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
btuC
ABC transporter (iron.B12.siderophore.hemin) , permease component

Position: -326
Score: 132.3
Sequence: TTTTACCGTCAGATC...
Locus tag: Pden_1354
Name: Cseg_1811
Funciton: hypothetical protein
Locus tag: Pden_1355
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Cseg_1811
hypothetical protein
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -284
Score: 121.4
Sequence: CTAACTGCAACGGTC...
Locus tag: Pden_4375
Name: nrdH
Funciton: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
Locus tag: Pden_4376
Name: nrdI
Funciton: Ribonucleotide reduction protein NrdI
Locus tag: Pden_4377
Name: nrdA
Funciton: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: Pden_4378
Name: nrdB
Funciton: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
nrdH
Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
nrdI
Ribonucleotide reduction protein NrdI
nrdA
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
nrdB
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)

Position: -322
Score: 101.5
Sequence: TACCAAGTCGCTGCA...
Locus tag: Pden_2980
Name: btuF
Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
Locus tag: Pden_2981
Name: btuC
Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component
Locus tag: Pden_2982
Name: btuD
Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
Locus tag: Pden_2983
Name: petE
Funciton: Pseudoazurin precursor
btuF
ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
btuC
ABC transporter (iron.B12.siderophore.hemin) , permease component
btuD
ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
petE
Pseudoazurin precursor

Position: -293
Score: 104.1
Sequence: GCGCTATGGCGGAGT...
Locus tag: Pden_1362
Name: btuF
Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
Locus tag: Pden_1361
Name: btuC
Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component
Locus tag: Pden_1360
Name: btuD
Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
Locus tag: Pden_1359
Name: petE
Funciton: Pseudoazurin precursor
btuF
ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
btuC
ABC transporter (iron.B12.siderophore.hemin) , permease component
btuD
ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
petE
Pseudoazurin precursor

Position: -349
Score: 101.9
Sequence: CAATGCGGGGCCGCT...
Locus tag: Pden_4382
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Pden_4383
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Pden_4384
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Pden_4385
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
btuB
Outer membrane vitamin B12 receptor BtuB
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD

Position: -347
Score: 131.2
Sequence: GCCATGAGGGCCGAG...
Locus tag: Pden_1368
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Pden_1367
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Pden_1366
Name: COG3313
Funciton: COG3313: Predicted Fe-S protein
btuB
Outer membrane vitamin B12 receptor BtuB
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
COG3313
COG3313: Predicted Fe-S protein

Position: -277
Score: 85.2
Sequence: CACAGACATGGGGCG...
Locus tag: Pden_2530
Name: cfrX
Funciton: Predicted metal-binding protein
Locus tag: Pden_2531
Name: cobW
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: Pden_2532
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: Pden_2533
Name: cobG
Funciton: Cobalamin biosynthesis protein CobG
Locus tag: Pden_2534
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Pden_2535
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Pden_2536
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
cfrX
Predicted metal-binding protein
cobW
CobW GTPase involved in cobalt insertion for B12 biosynthesis
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
cobG
Cobalamin biosynthesis protein CobG
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiH
Cobalt-precorrin-3b C17-methyltransferase
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Regulated Genes [ Tab delimited format ] DOWNLOAD
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