Regulon of Cobalamin in Paracoccus denitrificans PD1222

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Regulog:	Cobalamin - Rhodobacterales
Under regulation:
- Genes	39
- Operons	10

Member of regulog collections

By taxonomy - Rhodobacterales
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -241 Score: 133.6 Sequence: TAACATATGCGTGTA... Locus tag: Pden_2524 Name: cbtB Funciton: Putative cobalt transporter, subunit CbtB Locus tag: Pden_2525 Name: cbtA Funciton: Predicted cobalt transporter CbtA Locus tag: Pden_2526 Name: Pden_2526 Funciton: hypothetical protein Locus tag: Pden_2527 Name: bluB Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
	Pden_2524	cbtB	Putative cobalt transporter, subunit CbtB
	Pden_2525	cbtA	Predicted cobalt transporter CbtA
	Pden_2526	Pden_2526	hypothetical protein
	Pden_2527	bluB	Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
Position: -414 Score: 119 Sequence: CCCTATATGTAGGCA... Locus tag: Pden_2989 Name: nrdD Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) Locus tag: Pden_2988 Name: Pden_2988 Funciton: hypothetical protein Locus tag: Pden_2987 Name: nrdG Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
	Pden_2989	nrdD	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
	Pden_2988	Pden_2988	hypothetical protein
	Pden_2987	nrdG	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
Position: -408 Score: 127.9 Sequence: CTACACGGTCGGGTG... Locus tag: Pden_4827 Name: btuB Funciton: Outer membrane (iron.B12.siderophore.hemin) receptor Locus tag: Pden_4828 Name: btuD Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component Locus tag: Pden_4829 Name: btuF Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component Locus tag: Pden_4830 Name: btuC Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component
	Pden_4827	btuB	Outer membrane (iron.B12.siderophore.hemin) receptor
	Pden_4828	btuD	ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
	Pden_4829	btuF	ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
	Pden_4830	btuC	ABC transporter (iron.B12.siderophore.hemin) , permease component
Position: -326 Score: 132.3 Sequence: TTTTACCGTCAGATC... Locus tag: Pden_1354 Name: Cseg_1811 Funciton: hypothetical protein Locus tag: Pden_1355 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	Pden_1354	Cseg_1811	hypothetical protein
	Pden_1355	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -284 Score: 121.4 Sequence: CTAACTGCAACGGTC... Locus tag: Pden_4375 Name: nrdH Funciton: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib Locus tag: Pden_4376 Name: nrdI Funciton: Ribonucleotide reduction protein NrdI Locus tag: Pden_4377 Name: nrdA Funciton: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1) Locus tag: Pden_4378 Name: nrdB Funciton: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
	Pden_4375	nrdH	Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
	Pden_4376	nrdI	Ribonucleotide reduction protein NrdI
	Pden_4377	nrdA	Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
	Pden_4378	nrdB	Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
Position: -322 Score: 101.5 Sequence: TACCAAGTCGCTGCA... Locus tag: Pden_2980 Name: btuF Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component Locus tag: Pden_2981 Name: btuC Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component Locus tag: Pden_2982 Name: btuD Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component Locus tag: Pden_2983 Name: petE Funciton: Pseudoazurin precursor
	Pden_2980	btuF	ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
	Pden_2981	btuC	ABC transporter (iron.B12.siderophore.hemin) , permease component
	Pden_2982	btuD	ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
	Pden_2983	petE	Pseudoazurin precursor
Position: -293 Score: 104.1 Sequence: GCGCTATGGCGGAGT... Locus tag: Pden_1362 Name: btuF Funciton: ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component Locus tag: Pden_1361 Name: btuC Funciton: ABC transporter (iron.B12.siderophore.hemin) , permease component Locus tag: Pden_1360 Name: btuD Funciton: ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component Locus tag: Pden_1359 Name: petE Funciton: Pseudoazurin precursor
	Pden_1362	btuF	ABC transporter (iron.B12.siderophore.hemin) , periplasmic substrate-binding component
	Pden_1361	btuC	ABC transporter (iron.B12.siderophore.hemin) , permease component
	Pden_1360	btuD	ABC transporter (iron.B12.siderophore.hemin) , ATP-binding component
	Pden_1359	petE	Pseudoazurin precursor
Position: -349 Score: 101.9 Sequence: CAATGCGGGGCCGCT... Locus tag: Pden_4382 Name: btuB Funciton: Outer membrane vitamin B12 receptor BtuB Locus tag: Pden_4383 Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: Pden_4384 Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC Locus tag: Pden_4385 Name: btuD Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
	Pden_4382	btuB	Outer membrane vitamin B12 receptor BtuB
	Pden_4383	btuF	Vitamin B12 ABC transporter, B12-binding component BtuF
	Pden_4384	btuC	Vitamin B12 ABC transporter, permease component BtuC
	Pden_4385	btuD	Vitamin B12 ABC transporter, ATPase component BtuD
Position: -347 Score: 131.2 Sequence: GCCATGAGGGCCGAG... Locus tag: Pden_1368 Name: btuB Funciton: Outer membrane vitamin B12 receptor BtuB Locus tag: Pden_1367 Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: Pden_1366 Name: COG3313 Funciton: COG3313: Predicted Fe-S protein
	Pden_1368	btuB	Outer membrane vitamin B12 receptor BtuB
	Pden_1367	btuF	Vitamin B12 ABC transporter, B12-binding component BtuF
	Pden_1366	COG3313	COG3313: Predicted Fe-S protein
Position: -277 Score: 85.2 Sequence: CACAGACATGGGGCG... Locus tag: Pden_2530 Name: cfrX Funciton: Predicted metal-binding protein Locus tag: Pden_2531 Name: cobW Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis Locus tag: Pden_2532 Name: cobN Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis Locus tag: Pden_2533 Name: cobG Funciton: Cobalamin biosynthesis protein CobG Locus tag: Pden_2534 Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Locus tag: Pden_2535 Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Locus tag: Pden_2536 Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase
	Pden_2530	cfrX	Predicted metal-binding protein
	Pden_2531	cobW	CobW GTPase involved in cobalt insertion for B12 biosynthesis
	Pden_2532	cobN	CobN component of cobalt chelatase involved in B12 biosynthesis
	Pden_2533	cobG	Cobalamin biosynthesis protein CobG
	Pden_2534	cbiC	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
	Pden_2535	cbiL	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
	Pden_2536	cbiH	Cobalt-precorrin-3b C17-methyltransferase

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Cobalamin in Paracoccus denitrificans PD1222

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --