Regulon of CodY in Streptococcus thermophilus CNRZ1066

Properties
Regulator type:	Transcription factor
TF locus tag:	str1635
Regulator family:	CodY
Regulation mode:	repressor (activator)
Biological process:	Amino acid metabolism
Effector:	Guanosine triphosphate; Branched-chain amino acids
Regulog:	CodY - Streptococcaceae
Statistics of regulated genes:
- Genes	45
- Operons	24
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 273 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - CodY
By effector - Guanosine triphosphate
By effector - Branched-chain amino acids
By pathway - Amino acid metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -81 Score: 4.9 Sequence: AATATTTTGACAATT Locus tag: str0645 Name: aroA Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) Locus tag: str0646 Name: aroK Funciton: Shikimate kinase I (EC 2.7.1.71) Locus tag: str0647 Name: pheA Funciton: Prephenate dehydratase (EC 4.2.1.51)
	str0645	aroA	5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
	str0646	aroK	Shikimate kinase I (EC 2.7.1.71)
	str0647	pheA	Prephenate dehydratase (EC 4.2.1.51)
Position: -106 Score: 5 Sequence: ATTTTTCAGAAAATA Position: -33 Score: 5.2 Sequence: ATTATTCTGAAAATT Locus tag: str0745 Name: SMU.1109 Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
	str0745	SMU.1109	Predicted Mn2+/Fe2+ transporter, NRAMP family
Position: -59 Score: 5.4 Sequence: AATTTTCTGACAATT Locus tag: str1878 Name: thrC Funciton: Threonine synthase (EC 4.2.3.1)
	str1878	thrC	Threonine synthase (EC 4.2.3.1)
Position: -90 Score: 4.9 Sequence: AATTGTCAGAATTTT Locus tag: str0590 Name: ilvE Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
	str0590	ilvE	Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Position: -52 Score: 5 Sequence: AAGATTCTGAAAATT Locus tag: str0430 Name: gdhA Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
	str0430	gdhA	NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
Position: -76 Score: 4.7 Sequence: AATTTTCTGATAAAA Locus tag: str1445 Name: oppA2 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	str1445	oppA2	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Position: -194 Score: 4.6 Sequence: ATTTTTTAGAAAATA Position: -121 Score: 4.9 Sequence: ATTATTCTGAAAAAT Locus tag: str1443 Name: oppA2 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1) Locus tag: str1442 Name: oppA2 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1) Locus tag: str1441 Name: oppB2 Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1) Locus tag: str1440 Name: oppC2 Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1) Locus tag: str1439 Name: oppD2 Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1) Locus tag: str1438 Name: oppF2 Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
	str1443	oppA2	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	str1442	oppA2	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	str1441	oppB2	Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
	str1440	oppC2	Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
	str1439	oppD2	Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
	str1438	oppF2	Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
Position: -45 Score: 5.2 Sequence: AATTATCAAAAAATT Locus tag: str0494 Name: nrgA Funciton: Ammonium transporter Locus tag: str0495 Name: nrgB Funciton: Nitrogen regulatory protein P-II
	str0494	nrgA	Ammonium transporter
	str0495	nrgB	Nitrogen regulatory protein P-II
Position: -89 Score: 5 Sequence: AATTTTCTGAATACT Locus tag: str1263 Name: gapN Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
	str1263	gapN	Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Position: -27 Score: 5.2 Sequence: AATTTTTAGATAATT Locus tag: str1873 Name: ilvB Funciton: Acetolactate synthase large subunit (EC 2.2.1.6) Locus tag: str1872 Name: ilvN Funciton: Acetolactate synthase small subunit (EC 2.2.1.6) Locus tag: str1871 Name: ilvC Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
	str1873	ilvB	Acetolactate synthase large subunit (EC 2.2.1.6)
	str1872	ilvN	Acetolactate synthase small subunit (EC 2.2.1.6)
	str1871	ilvC	Ketol-acid reductoisomerase (EC 1.1.1.86)
Position: -60 Score: 5.4 Sequence: ATTTTTCTGAAAATT Locus tag: str0150 Name: ilvA Funciton: Threonine dehydratase (EC 4.3.1.19)
	str0150	ilvA	Threonine dehydratase (EC 4.3.1.19)
Position: -132 Score: 5.4 Sequence: AATTTTCAGACAATT Locus tag: str1635 Name: codY Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family Locus tag: str1634 Name: pncA Funciton: Nicotinamidase (EC 3.5.1.19)
	str1635	codY	Nutrient limitation global transcriptional regulator CodY, CodY family
	str1634	pncA	Nicotinamidase (EC 3.5.1.19)
Position: -61 Score: 4.7 Sequence: ATTTTTTAGACAATT Locus tag: str1604 Name: ilvD Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
	str1604	ilvD	Dihydroxy-acid dehydratase (EC 4.2.1.9)
Position: -57 Score: 5.1 Sequence: AATTTTCAGAAATTA Locus tag: str0229 Name: pepC Funciton: Aminopeptidase C (EC 3.4.22.40)
	str0229	pepC	Aminopeptidase C (EC 3.4.22.40)
Position: -70 Score: 4.6 Sequence: AATATTCTGTCAATT Locus tag: str0469 Name: hom Funciton: Homoserine dehydrogenase (EC 1.1.1.3) Locus tag: str0470 Name: thrB Funciton: Homoserine kinase (EC 2.7.1.39)
	str0469	hom	Homoserine dehydrogenase (EC 1.1.1.3)
	str0470	thrB	Homoserine kinase (EC 2.7.1.39)
Position: -74 Score: 5.5 Sequence: AAATTTCTGAAAATT Locus tag: str0280 Name: ureI Funciton: Urea channel UreI Locus tag: str0281 Name: ureA Funciton: Urease gamma subunit (EC 3.5.1.5) Locus tag: str0282 Name: ureB Funciton: Urease beta subunit (EC 3.5.1.5) Locus tag: str0283 Name: ureC Funciton: Urease alpha subunit (EC 3.5.1.5)
	str0280	ureI	Urea channel UreI
	str0281	ureA	Urease gamma subunit (EC 3.5.1.5)
	str0282	ureB	Urease beta subunit (EC 3.5.1.5)
	str0283	ureC	Urease alpha subunit (EC 3.5.1.5)
Position: -80 Score: 5 Sequence: AATATTCCGAAAATT Locus tag: str1199 Name: yfjA Funciton: Conserved hypothetical protein
	str1199	yfjA	Conserved hypothetical protein
Position: -38 Score: 4.6 Sequence: AAAATTCAGAATATA Locus tag: str1777 Name: glnR Funciton: Nitrogen metabolism transcriptional regulator GlnR, MerR family Locus tag: str1776 Name: glnA Funciton: Glutamine synthetase type I (EC 6.3.1.2)
	str1777	glnR	Nitrogen metabolism transcriptional regulator GlnR, MerR family
	str1776	glnA	Glutamine synthetase type I (EC 6.3.1.2)
Position: -108 Score: 4.9 Sequence: AAAAGTCAGAAAATT Locus tag: str0718 Name: ppc Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
	str0718	ppc	Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
Position: -171 Score: 4.6 Sequence: AAAGTTCTAAAAATT Locus tag: str1868 Name: rpoB Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) Locus tag: str1867 Name: rpoC Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
	str1868	rpoB	DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
	str1867	rpoC	DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
Position: -53 Score: 4.5 Sequence: CGTTTTCAGAAAATT Locus tag: str1297 Name: dapA Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
	str1297	dapA	Dihydrodipicolinate synthase (EC 4.2.1.52)
Position: -56 Score: 5.1 Sequence: AATTATCAGAATTTT Locus tag: str0378 Name: thrA Funciton: Aspartokinase (EC 2.7.2.4)
	str0378	thrA	Aspartokinase (EC 2.7.2.4)
Position: -108 Score: 4.7 Sequence: AATATTCTGAATTAT Locus tag: str0509 Name: aapA Funciton: Amino acid permease
	str0509	aapA	Amino acid permease
Position: -65 Score: 5.6 Sequence: AATTTTCTGATAATT Locus tag: str0359 Name: livK Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1) Locus tag: str0360 Name: livH Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1) Locus tag: str0361 Name: livM Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1) Locus tag: str0362 Name: livG Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1) Locus tag: str0363 Name: livF Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
	str0359	livK	Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
	str0360	livH	Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
	str0361	livM	Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
	str0362	livG	Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
	str0363	livF	Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of CodY in Streptococcus thermophilus CNRZ1066

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --