Regulon of CodY in Streptococcus pneumoniae TIGR4

Properties
Regulator type:	Transcription factor
TF locus tag:	SP_1584
Regulator family:	CodY
Regulation mode:	repressor (activator)
Biological process:	Amino acid metabolism
Effector:	Guanosine triphosphate; Branched-chain amino acids
Regulog:	CodY - Streptococcaceae
Statistics of regulated genes:
- Genes	42
- Operons	20
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 273 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - CodY
By effector - Guanosine triphosphate
By effector - Branched-chain amino acids
By pathway - Amino acid metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -71 Score: 5.3 Sequence: AAAATTCTGAAAATT Locus tag: SP_0366 Name: oppA2 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	SP_0366	oppA2	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Position: -87 Score: 5.6 Sequence: AATATTCTGAAAATT Locus tag: SP_1891 Name: oppA2 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1) Locus tag: SP_1890 Name: oppB2 Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1) Locus tag: SP_1889 Name: oppC2 Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1) Locus tag: SP_1888 Name: oppD2 Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1) Locus tag: SP_1887 Name: oppF2 Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
	SP_1891	oppA2	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	SP_1890	oppB2	Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
	SP_1889	oppC2	Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
	SP_1888	oppD2	Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
	SP_1887	oppF2	Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
Position: -71 Score: 5.6 Sequence: AATTTTCAGATAATT Locus tag: SP_1584 Name: codY Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family Locus tag: SP_1583 Name: pncA Funciton: Nicotinamidase (EC 3.5.1.19)
	SP_1584	codY	Nutrient limitation global transcriptional regulator CodY, CodY family
	SP_1583	pncA	Nicotinamidase (EC 3.5.1.19)
Position: -94 Score: 5.5 Sequence: AATTTTTAGAAAATT Locus tag: SP_1306 Name: gdhA Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
	SP_1306	gdhA	NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
Position: -88 Score: 5.8 Sequence: AATTTTCTGAAAATT Locus tag: SP_0856 Name: ilvE Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
	SP_0856	ilvE	Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Position: -33 Score: 5.2 Sequence: ATTATTCTGAAAATT Locus tag: SP_0159 Name: SMU.1109 Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
	SP_0159	SMU.1109	Predicted Mn2+/Fe2+ transporter, NRAMP family
Position: -55 Score: 5.2 Sequence: GATTTTCTGAAAATT Locus tag: SP_1119 Name: gapN Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
	SP_1119	gapN	Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Position: -55 Score: 4.7 Sequence: AATTGTCAGATAATA Locus tag: SP_1578 Name: ubiE Funciton: SAM-dependent methyltransferase
	SP_1578	ubiE	SAM-dependent methyltransferase
Position: -57 Score: 5.4 Sequence: AATTTTCTGAAAAAT Locus tag: SP_2066 Name: thrC Funciton: Threonine synthase (EC 4.2.3.1)
	SP_2066	thrC	Threonine synthase (EC 4.2.3.1)
Position: -93 Score: 5.3 Sequence: AAAATTCAGAAAATT Locus tag: SP_0445 Name: ilvB Funciton: Acetolactate synthase large subunit (EC 2.2.1.6) Locus tag: SP_0446 Name: ilvN Funciton: Acetolactate synthase small subunit (EC 2.2.1.6) Locus tag: SP_0447 Name: ilvC Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86) Locus tag: SP_0448 Name: SP_0448 Funciton: Hypothetical protein Locus tag: SP_0449 Name: SP_0449 Funciton: Hypothetical protein Locus tag: SP_0450 Name: ilvA Funciton: Threonine dehydratase (EC 4.3.1.19)
	SP_0445	ilvB	Acetolactate synthase large subunit (EC 2.2.1.6)
	SP_0446	ilvN	Acetolactate synthase small subunit (EC 2.2.1.6)
	SP_0447	ilvC	Ketol-acid reductoisomerase (EC 1.1.1.86)
	SP_0448	SP_0448	Hypothetical protein
	SP_0449	SP_0449	Hypothetical protein
	SP_0450	ilvA	Threonine dehydratase (EC 4.3.1.19)
Position: -112 Score: 5 Sequence: AAGATTCTGAAAATT Locus tag: SP_1961 Name: rpoB Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) Locus tag: SP_1960 Name: rpoC Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
	SP_1961	rpoB	DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
	SP_1960	rpoC	DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
Position: -85 Score: 5.8 Sequence: AATTTTCTGAAAATT Locus tag: SP_2126 Name: ilvD Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
	SP_2126	ilvD	Dihydroxy-acid dehydratase (EC 4.2.1.9)
Position: -80 Score: 5.2 Sequence: AATTGTCAGAAATTT Locus tag: SP_1869 Name: fatD Funciton: Iron-siderophore ABC transporter, permease protein 1 Locus tag: SP_1870 Name: fatC Funciton: Iron-siderophore ABC transporter, permease protein 2 Locus tag: SP_1871 Name: fatA Funciton: Iron-siderophore ABC transporter, ATP-binding protein Locus tag: SP_1872 Name: fatB Funciton: Iron-siderophore ABC transporter, substrate-binding protein
	SP_1869	fatD	Iron-siderophore ABC transporter, permease protein 1
	SP_1870	fatC	Iron-siderophore ABC transporter, permease protein 2
	SP_1871	fatA	Iron-siderophore ABC transporter, ATP-binding protein
	SP_1872	fatB	Iron-siderophore ABC transporter, substrate-binding protein
Position: -31 Score: 5.5 Sequence: AATTTTTAGAAAATT Locus tag: SP_1013 Name: asd Funciton: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Locus tag: SP_1014 Name: dapA Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
	SP_1013	asd	Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
	SP_1014	dapA	Dihydrodipicolinate synthase (EC 4.2.1.52)
Position: -183 Score: 4.4 Sequence: TAATTTCTAATAATT Locus tag: SP_0754 Name: acuB Funciton: Acetoin utilization protein AcuB
	SP_0754	acuB	Acetoin utilization protein AcuB
Position: -69 Score: 4.7 Sequence: AACTATCAGAATATT Locus tag: SP_0141 Name: mutR Funciton: Predicted transcriptional regulator, Xre family
	SP_0141	mutR	Predicted transcriptional regulator, Xre family
Position: -56 Score: 5.2 Sequence: AATTTTCACAAAATT Locus tag: SP_1361 Name: hom Funciton: Homoserine dehydrogenase (EC 1.1.1.3) Locus tag: SP_1360 Name: thrB Funciton: Homoserine kinase (EC 2.7.1.39)
	SP_1361	hom	Homoserine dehydrogenase (EC 1.1.1.3)
	SP_1360	thrB	Homoserine kinase (EC 2.7.1.39)
Position: -41 Score: 5 Sequence: AAAATTTAGAAAATT Locus tag: SP_0095 Name: ymdE Funciton: Conserved hypothetical protein
	SP_0095	ymdE	Conserved hypothetical protein
Position: -183 Score: 5.3 Sequence: AAATTTCAGAAATTT Locus tag: SP_0711 Name: str1582 Funciton: Predicted amino acid ABC transporter, permease protein 1 Locus tag: SP_0710 Name: str1581 Funciton: Predicted amino acid ABC transporter, permease protein 2 Locus tag: SP_0709 Name: str1580 Funciton: Predicted amino acid ABC transporter, ATP-binding protein
	SP_0711	str1582	Predicted amino acid ABC transporter, permease protein 1
	SP_0710	str1581	Predicted amino acid ABC transporter, permease protein 2
	SP_0709	str1580	Predicted amino acid ABC transporter, ATP-binding protein
Position: -60 Score: 5.6 Sequence: AATTTTCTGATAATT Locus tag: SP_0749 Name: livK Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1) Locus tag: SP_0750 Name: livH Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1) Locus tag: SP_0751 Name: livM Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1) Locus tag: SP_0752 Name: livG Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1) Locus tag: SP_0753 Name: livF Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
	SP_0749	livK	Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
	SP_0750	livH	Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
	SP_0751	livM	Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
	SP_0752	livG	Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
	SP_0753	livF	Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of CodY in Streptococcus pneumoniae TIGR4

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --