Regulon of CodY in Streptococcus mutans UA159

Properties
Regulator type:	Transcription factor
TF locus tag:	SMU.1824c
Regulator family:	CodY
Regulation mode:	repressor (activator)
Biological process:	Amino acid metabolism
Effector:	Guanosine triphosphate; Branched-chain amino acids
Regulog:	CodY - Streptococcaceae
Statistics of regulated genes:
- Genes	58
- Operons	24
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 273 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - CodY
By effector - Guanosine triphosphate
By effector - Branched-chain amino acids
By pathway - Amino acid metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -84 Score: 5.3 Sequence: AAAATTCTGAAAATT Locus tag: SMU.1990 Name: rpoB Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) Locus tag: SMU.1989 Name: rpoC Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
	SMU.1990	rpoB	DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
	SMU.1989	rpoC	DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
Position: -59 Score: 5.2 Sequence: AATTGTCTGATAATT Locus tag: SMU.70 Name: thrC Funciton: Threonine synthase (EC 4.2.3.1)
	SMU.70	thrC	Threonine synthase (EC 4.2.3.1)
Position: -68 Score: 5.6 Sequence: AATATTCAGAAAATT Locus tag: SMU.913 Name: gdhA Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
	SMU.913	gdhA	NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
Position: -89 Score: 5.3 Sequence: AATTTTCTGAATTTT Locus tag: SMU.676 Name: gapN Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
	SMU.676	gapN	Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
Position: -75 Score: 5.4 Sequence: AATTTTCTGACAATT Locus tag: SMU.1824c Name: codY Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family Locus tag: SMU.1823 Name: pncA Funciton: Nicotinamidase (EC 3.5.1.19)
	SMU.1824c	codY	Nutrient limitation global transcriptional regulator CodY, CodY family
	SMU.1823	pncA	Nicotinamidase (EC 3.5.1.19)
Position: -105 Score: 5.3 Sequence: AATTTTCTGAAAATA Locus tag: SMU.1109c Name: SMU.1109 Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
	SMU.1109c	SMU.1109	Predicted Mn2+/Fe2+ transporter, NRAMP family
Position: -36 Score: 5.3 Sequence: AATTTTCAGATTATT Locus tag: SMU.255 Name: oppA1 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1) Locus tag: SMU.256 Name: oppB1 Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1) Locus tag: SMU.257 Name: oppC1 Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1) Locus tag: SMU.258 Name: oppD1 Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1) Locus tag: SMU.259 Name: oppF1 Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
	SMU.255	oppA1	Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
	SMU.256	oppB1	Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
	SMU.257	oppC1	Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
	SMU.258	oppD1	Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
	SMU.259	oppF1	Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
Position: -50 Score: 5.3 Sequence: AAAATTCTGAAAATT Locus tag: SMU.1656 Name: serC Funciton: Phosphoserine aminotransferase (EC 2.6.1.52) Locus tag: SMU.1655c Name: SMU.1655c Funciton: Hypothetical protein Locus tag: SMU.1654c Name: yesJ Funciton: Acetyltransferase (EC 2.3.1.-), GNAT family Locus tag: SMU.1653 Name: serA Funciton: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
	SMU.1656	serC	Phosphoserine aminotransferase (EC 2.6.1.52)
	SMU.1655c	SMU.1655c	Hypothetical protein
	SMU.1654c	yesJ	Acetyltransferase (EC 2.3.1.-), GNAT family
	SMU.1653	serA	D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
Position: -310 Score: 5.1 Sequence: AATATTCAGAATTTT Locus tag: SMU.1273 Name: hisC Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9) Locus tag: SMU.1272 Name: hisZ Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) Locus tag: SMU.1271 Name: hisG Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17) Locus tag: SMU.1270 Name: hisD Funciton: Histidinol dehydrogenase (EC 1.1.1.23) Locus tag: SMU.1269 Name: serB Funciton: Phosphoserine phosphatase (EC 3.1.3.3) Locus tag: SMU.1268 Name: hisB Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) Locus tag: SMU.1267c Name: null Funciton: hypothetical protein Locus tag: SMU.1266 Name: hisH Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
	SMU.1273	hisC	Histidinol-phosphate aminotransferase (EC 2.6.1.9)
	SMU.1272	hisZ	ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
	SMU.1271	hisG	ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
	SMU.1270	hisD	Histidinol dehydrogenase (EC 1.1.1.23)
	SMU.1269	serB	Phosphoserine phosphatase (EC 3.1.3.3)
	SMU.1268	hisB	Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
	SMU.1267c		hypothetical protein
	SMU.1266	hisH	Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
Position: -85 Score: 5.5 Sequence: AATTTTTAGAAAATT Locus tag: SMU.1658 Name: nrgA Funciton: Ammonium transporter Locus tag: SMU.1657c Name: nrgB Funciton: Nitrogen regulatory protein P-II
	SMU.1658	nrgA	Ammonium transporter
	SMU.1657c	nrgB	Nitrogen regulatory protein P-II
Position: -108 Score: 5.3 Sequence: AATTTTCAGAATTTT Locus tag: SMU.365 Name: gltB Funciton: Glutamate synthase [NADPH] large chain (EC 1.4.1.13) Locus tag: SMU.366 Name: gltD Funciton: Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
	SMU.365	gltB	Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
	SMU.366	gltD	Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
Position: -83 Score: 5.3 Sequence: AATTTTCAGAATTTT Locus tag: SMU.1203 Name: ilvE Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
	SMU.1203	ilvE	Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Position: -246 Score: 5.4 Sequence: ATTTTTCAGAAAATT Locus tag: SMU.1384 Name: leuA Funciton: 2-isopropylmalate synthase (EC 2.3.3.13) Locus tag: SMU.1383 Name: leuB Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85) Locus tag: SMU.1382 Name: leuC Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) Locus tag: SMU.1381 Name: leuD Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
	SMU.1384	leuA	2-isopropylmalate synthase (EC 2.3.3.13)
	SMU.1383	leuB	3-isopropylmalate dehydrogenase (EC 1.1.1.85)
	SMU.1382	leuC	3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
	SMU.1381	leuD	3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Position: -65 Score: 5.1 Sequence: TATTTTCAGAATATT Locus tag: SMU.1301c Name: ubiE Funciton: SAM-dependent methyltransferase
	SMU.1301c	ubiE	SAM-dependent methyltransferase
Position: -42 Score: 5.5 Sequence: AATTTTTTGAAAATT Locus tag: SMU.231 Name: ilvB Funciton: Acetolactate synthase large subunit (EC 2.2.1.6) Locus tag: SMU.232 Name: ilvN Funciton: Acetolactate synthase small subunit (EC 2.2.1.6) Locus tag: SMU.233 Name: ilvC Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86) Locus tag: SMU.234 Name: ilvA Funciton: Threonine dehydratase (EC 4.3.1.19)
	SMU.231	ilvB	Acetolactate synthase large subunit (EC 2.2.1.6)
	SMU.232	ilvN	Acetolactate synthase small subunit (EC 2.2.1.6)
	SMU.233	ilvC	Ketol-acid reductoisomerase (EC 1.1.1.86)
	SMU.234	ilvA	Threonine dehydratase (EC 4.3.1.19)
Position: -136 Score: 5.1 Sequence: AAAATTCTGAATATT Locus tag: SMU.1595 Name: cah Funciton: Carbonic anhydrase precursor (EC 4.2.1.1)
	SMU.1595	cah	Carbonic anhydrase precursor (EC 4.2.1.1)
Position: -139 Score: 5.3 Sequence: AATTTTCTGAATTTT Locus tag: SMU.63c Name: SMU.63c Funciton: Conserved hypothetical secreted protein
	SMU.63c	SMU.63c	Conserved hypothetical secreted protein
Position: -291 Score: 4.7 Sequence: AATTTTCAGAAAAGA Locus tag: SMU.1175 Name: dagA Funciton: Sodium/glycine symporter
	SMU.1175	dagA	Sodium/glycine symporter
Position: -101 Score: 5.1 Sequence: AATTTTCTGATAATA Locus tag: SMU.1519 Name: gluQ Funciton: Glutamate ABC transporter, ATP-binding protein Locus tag: SMU.1520 Name: gluH Funciton: Glutamate ABC transporter, substrate-binding protein Locus tag: SMU.1521 Name: gluM Funciton: Glutamate ABC transporter, permease protein 1 Locus tag: SMU.1522 Name: gluP Funciton: Glutamate ABC transporter, permease protein 2
	SMU.1519	gluQ	Glutamate ABC transporter, ATP-binding protein
	SMU.1520	gluH	Glutamate ABC transporter, substrate-binding protein
	SMU.1521	gluM	Glutamate ABC transporter, permease protein 1
	SMU.1522	gluP	Glutamate ABC transporter, permease protein 2
Position: -39 Score: 5.1 Sequence: AATTTTCAGAATATA Locus tag: SMU.363 Name: glnR Funciton: Nitrogen metabolism transcriptional regulator GlnR, MerR family Locus tag: SMU.364 Name: glnA Funciton: Glutamine synthetase type I (EC 6.3.1.2)
	SMU.363	glnR	Nitrogen metabolism transcriptional regulator GlnR, MerR family
	SMU.364	glnA	Glutamine synthetase type I (EC 6.3.1.2)
Position: -53 Score: 5.3 Sequence: AATTTTCTGAATTTT Locus tag: SMU.1748 Name: thrA Funciton: Aspartokinase (EC 2.7.2.4)
	SMU.1748	thrA	Aspartokinase (EC 2.7.2.4)
Position: -154 Score: 5 Sequence: AATCTTCTGAATATT Locus tag: SMU.1309c Name: gldA2 Funciton: Glycerol dehydrogenase (EC 1.1.1.6)
	SMU.1309c	gldA2	Glycerol dehydrogenase (EC 1.1.1.6)
Position: -61 Score: 5.2 Sequence: AATTTTCTAAAATTT Locus tag: SMU.784 Name: aroA Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) Locus tag: SMU.785 Name: aroK Funciton: Shikimate kinase I (EC 2.7.1.71) Locus tag: SMU.786 Name: pheA Funciton: Prephenate dehydratase (EC 4.2.1.51)
	SMU.784	aroA	5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
	SMU.785	aroK	Shikimate kinase I (EC 2.7.1.71)
	SMU.786	pheA	Prephenate dehydratase (EC 4.2.1.51)
Position: -66 Score: 5.3 Sequence: AATATTCAGATAATT Locus tag: SMU.1669 Name: livK Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1) Locus tag: SMU.1668 Name: livH Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1) Locus tag: SMU.1667 Name: livM Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1) Locus tag: SMU.1666 Name: livG Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1) Locus tag: SMU.1665 Name: livF Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
	SMU.1669	livK	Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
	SMU.1668	livH	Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
	SMU.1667	livM	Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
	SMU.1666	livG	Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
	SMU.1665	livF	Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of CodY in Streptococcus mutans UA159

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --