Regulon of CodY in Streptococcus mutans UA159
| Regulator type: | Transcription factor |
| TF locus tag: | SMU.1824c |
| Regulator family: | CodY |
| Regulation mode: | repressor (activator) |
| Biological process: | Amino acid metabolism |
| Effector: | Guanosine triphosphate; Branched-chain amino acids |
| Regulog: | CodY - Streptococcaceae |
| Statistics of regulated genes: | |
| - Genes | 58 |
| - Operons | 24 |
| Visualization: | |
|
Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Streptococcaceae
- By TF family - CodY
- By effector - Guanosine triphosphate
- By effector - Branched-chain amino acids
- By pathway - Amino acid metabolism
| Locus Tag | Name | Function | |
|---|---|---|---|
|
Position: -84
Score: 5.3 Sequence: AAAATTCTGAAAATT
Locus tag: SMU.1990
Name: rpoB Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
Locus tag: SMU.1989
Name: rpoC Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6) |
|||
|
rpoB
|
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
|
||
|
rpoC
|
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
|
||
|
Position: -59
Score: 5.2 Sequence: AATTGTCTGATAATT
Locus tag: SMU.70
Name: thrC Funciton: Threonine synthase (EC 4.2.3.1) |
|||
|
thrC
|
Threonine synthase (EC 4.2.3.1)
|
||
|
Position: -68
Score: 5.6 Sequence: AATATTCAGAAAATT
Locus tag: SMU.913
Name: gdhA Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4) |
|||
|
gdhA
|
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
|
||
|
Position: -89
Score: 5.3 Sequence: AATTTTCTGAATTTT
Locus tag: SMU.676
Name: gapN Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9) |
|||
|
gapN
|
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
|
||
|
Position: -75
Score: 5.4 Sequence: AATTTTCTGACAATT
Locus tag: SMU.1824c
Name: codY Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family
Locus tag: SMU.1823
Name: pncA Funciton: Nicotinamidase (EC 3.5.1.19) |
|||
|
codY
|
Nutrient limitation global transcriptional regulator CodY, CodY family
|
||
|
pncA
|
Nicotinamidase (EC 3.5.1.19)
|
||
|
Position: -105
Score: 5.3 Sequence: AATTTTCTGAAAATA
Locus tag: SMU.1109c
Name: SMU.1109 Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family |
|||
|
SMU.1109
|
Predicted Mn2+/Fe2+ transporter, NRAMP family
|
||
|
Position: -36
Score: 5.3 Sequence: AATTTTCAGATTATT
Locus tag: SMU.255
Name: oppA1 Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: SMU.256
Name: oppB1 Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
Locus tag: SMU.257
Name: oppC1 Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
Locus tag: SMU.258
Name: oppD1 Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
Locus tag: SMU.259
Name: oppF1 Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1) |
|||
|
oppA1
|
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
|
||
|
oppB1
|
Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
|
||
|
oppC1
|
Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
|
||
|
oppD1
|
Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
|
||
|
oppF1
|
Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
|
||
|
Position: -50
Score: 5.3 Sequence: AAAATTCTGAAAATT
Locus tag: SMU.1656
Name: serC Funciton: Phosphoserine aminotransferase (EC 2.6.1.52)
Locus tag: SMU.1655c
Name: SMU.1655c Funciton: Hypothetical protein
Locus tag: SMU.1654c
Name: yesJ Funciton: Acetyltransferase (EC 2.3.1.-), GNAT family
Locus tag: SMU.1653
Name: serA Funciton: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) |
|||
|
serC
|
Phosphoserine aminotransferase (EC 2.6.1.52)
|
||
|
SMU.1655c
|
Hypothetical protein
|
||
|
yesJ
|
Acetyltransferase (EC 2.3.1.-), GNAT family
|
||
|
serA
|
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
|
||
|
Position: -310
Score: 5.1 Sequence: AATATTCAGAATTTT
Locus tag: SMU.1273
Name: hisC Funciton: Histidinol-phosphate aminotransferase (EC 2.6.1.9)
Locus tag: SMU.1272
Name: hisZ Funciton: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
Locus tag: SMU.1271
Name: hisG Funciton: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
Locus tag: SMU.1270
Name: hisD Funciton: Histidinol dehydrogenase (EC 1.1.1.23)
Locus tag: SMU.1269
Name: serB Funciton: Phosphoserine phosphatase (EC 3.1.3.3)
Locus tag: SMU.1268
Name: hisB Funciton: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
Locus tag: SMU.1267c
Name: null Funciton: hypothetical protein
Locus tag: SMU.1266
Name: hisH Funciton: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) |
|||
|
hisC
|
Histidinol-phosphate aminotransferase (EC 2.6.1.9)
|
||
|
hisZ
|
ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
|
||
|
hisG
|
ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
|
||
|
hisD
|
Histidinol dehydrogenase (EC 1.1.1.23)
|
||
|
serB
|
Phosphoserine phosphatase (EC 3.1.3.3)
|
||
|
hisB
|
Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
|
||
|
hypothetical protein
|
|||
|
hisH
|
Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
|
||
|
Position: -85
Score: 5.5 Sequence: AATTTTTAGAAAATT
Locus tag: SMU.1658
Name: nrgA Funciton: Ammonium transporter
Locus tag: SMU.1657c
Name: nrgB Funciton: Nitrogen regulatory protein P-II |
|||
|
nrgA
|
Ammonium transporter
|
||
|
nrgB
|
Nitrogen regulatory protein P-II
|
||
|
Position: -108
Score: 5.3 Sequence: AATTTTCAGAATTTT
Locus tag: SMU.365
Name: gltB Funciton: Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
Locus tag: SMU.366
Name: gltD Funciton: Glutamate synthase [NADPH] small chain (EC 1.4.1.13) |
|||
|
gltB
|
Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
|
||
|
gltD
|
Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
|
||
|
Position: -83
Score: 5.3 Sequence: AATTTTCAGAATTTT
Locus tag: SMU.1203
Name: ilvE Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42) |
|||
|
ilvE
|
Branched-chain amino acid aminotransferase (EC 2.6.1.42)
|
||
|
Position: -246
Score: 5.4 Sequence: ATTTTTCAGAAAATT
Locus tag: SMU.1384
Name: leuA Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: SMU.1383
Name: leuB Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: SMU.1382
Name: leuC Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: SMU.1381
Name: leuD Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) |
|||
|
leuA
|
2-isopropylmalate synthase (EC 2.3.3.13)
|
||
|
leuB
|
3-isopropylmalate dehydrogenase (EC 1.1.1.85)
|
||
|
leuC
|
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
|
||
|
leuD
|
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
|
||
|
Position: -65
Score: 5.1 Sequence: TATTTTCAGAATATT
Locus tag: SMU.1301c
Name: ubiE Funciton: SAM-dependent methyltransferase |
|||
|
ubiE
|
SAM-dependent methyltransferase
|
||
|
Position: -42
Score: 5.5 Sequence: AATTTTTTGAAAATT
Locus tag: SMU.231
Name: ilvB Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: SMU.232
Name: ilvN Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: SMU.233
Name: ilvC Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
Locus tag: SMU.234
Name: ilvA Funciton: Threonine dehydratase (EC 4.3.1.19) |
|||
|
ilvB
|
Acetolactate synthase large subunit (EC 2.2.1.6)
|
||
|
ilvN
|
Acetolactate synthase small subunit (EC 2.2.1.6)
|
||
|
ilvC
|
Ketol-acid reductoisomerase (EC 1.1.1.86)
|
||
|
ilvA
|
Threonine dehydratase (EC 4.3.1.19)
|
||
|
Position: -136
Score: 5.1 Sequence: AAAATTCTGAATATT
Locus tag: SMU.1595
Name: cah Funciton: Carbonic anhydrase precursor (EC 4.2.1.1) |
|||
|
cah
|
Carbonic anhydrase precursor (EC 4.2.1.1)
|
||
|
Position: -139
Score: 5.3 Sequence: AATTTTCTGAATTTT
Locus tag: SMU.63c
Name: SMU.63c Funciton: Conserved hypothetical secreted protein |
|||
|
SMU.63c
|
Conserved hypothetical secreted protein
|
||
|
Position: -291
Score: 4.7 Sequence: AATTTTCAGAAAAGA
Locus tag: SMU.1175
Name: dagA Funciton: Sodium/glycine symporter |
|||
|
dagA
|
Sodium/glycine symporter
|
||
|
Position: -101
Score: 5.1 Sequence: AATTTTCTGATAATA
Locus tag: SMU.1519
Name: gluQ Funciton: Glutamate ABC transporter, ATP-binding protein
Locus tag: SMU.1520
Name: gluH Funciton: Glutamate ABC transporter, substrate-binding protein
Locus tag: SMU.1521
Name: gluM Funciton: Glutamate ABC transporter, permease protein 1
Locus tag: SMU.1522
Name: gluP Funciton: Glutamate ABC transporter, permease protein 2 |
|||
|
gluQ
|
Glutamate ABC transporter, ATP-binding protein
|
||
|
gluH
|
Glutamate ABC transporter, substrate-binding protein
|
||
|
gluM
|
Glutamate ABC transporter, permease protein 1
|
||
|
gluP
|
Glutamate ABC transporter, permease protein 2
|
||
|
Position: -39
Score: 5.1 Sequence: AATTTTCAGAATATA
Locus tag: SMU.363
Name: glnR Funciton: Nitrogen metabolism transcriptional regulator GlnR, MerR family
Locus tag: SMU.364
Name: glnA Funciton: Glutamine synthetase type I (EC 6.3.1.2) |
|||
|
glnR
|
Nitrogen metabolism transcriptional regulator GlnR, MerR family
|
||
|
glnA
|
Glutamine synthetase type I (EC 6.3.1.2)
|
||
|
Position: -53
Score: 5.3 Sequence: AATTTTCTGAATTTT
Locus tag: SMU.1748
Name: thrA Funciton: Aspartokinase (EC 2.7.2.4) |
|||
|
thrA
|
Aspartokinase (EC 2.7.2.4)
|
||
|
Position: -154
Score: 5 Sequence: AATCTTCTGAATATT
Locus tag: SMU.1309c
Name: gldA2 Funciton: Glycerol dehydrogenase (EC 1.1.1.6) |
|||
|
gldA2
|
Glycerol dehydrogenase (EC 1.1.1.6)
|
||
|
Position: -61
Score: 5.2 Sequence: AATTTTCTAAAATTT
Locus tag: SMU.784
Name: aroA Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
Locus tag: SMU.785
Name: aroK Funciton: Shikimate kinase I (EC 2.7.1.71)
Locus tag: SMU.786
Name: pheA Funciton: Prephenate dehydratase (EC 4.2.1.51) |
|||
|
aroA
|
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
|
||
|
aroK
|
Shikimate kinase I (EC 2.7.1.71)
|
||
|
pheA
|
Prephenate dehydratase (EC 4.2.1.51)
|
||
|
Position: -66
Score: 5.3 Sequence: AATATTCAGATAATT
Locus tag: SMU.1669
Name: livK Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
Locus tag: SMU.1668
Name: livH Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
Locus tag: SMU.1667
Name: livM Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
Locus tag: SMU.1666
Name: livG Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
Locus tag: SMU.1665
Name: livF Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1) |
|||
|
livK
|
Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
|
||
|
livH
|
Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
|
||
|
livM
|
Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
|
||
|
livG
|
Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
|
||
|
livF
|
Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
|
||
|
Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |