Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Shewanella sp MR-4

Properties
Regulator type: Transcription factor
TF locus tag: Shewmr4_3440
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine biosynthesis; Methionine metabolism
Effector: S-adenosylmethionine
Regulog: MetJ - Shewanellaceae
Statistics of regulated genes:
- Genes 14
- Operons 12
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 397 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -101
Score: 6.4
Sequence: GGACATAT-(0)-AGACGTCC
Position: -93
Score: 6.8
Sequence: AGACGTCC-(0)-AAACGTCC
Locus tag: Shewmr4_3437
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -48
Score: 6.2
Sequence: AGGCGTAT-(0)-AGACATCC
Position: -40
Score: 6.7
Sequence: AGACATCC-(0)-AGAAGTCT
Locus tag: Shewmr4_2599
Name: COG3126
Funciton: Lipoprotein-related protein
Locus tag: Shewmr4_2598
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
COG3126
Lipoprotein-related protein
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -94
Score: 7.3
Sequence: AGACGTCT-(0)-AAACGTCT
Position: -39
Score: 7.2
Sequence: AGACGTCC-(0)-AGACATCT
Locus tag: Shewmr4_3439
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: Shewmr4_3438
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -126
Score: 6.6
Sequence: AAACTTCT-(0)-AGACGTCC
Position: -118
Score: 6.5
Sequence: AGACGTCC-(0)-AGACGCCC
Locus tag: Shewmr4_3299
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -59
Score: 5.8
Sequence: AGCCGTCT-(0)-AGATGTAG
Locus tag: Shewmr4_0772
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)

Position: -160
Score: 6.2
Sequence: AAACATTT-(0)-AGACTTCT
Position: -152
Score: 6.6
Sequence: AGACTTCT-(0)-AGATGTCC
Locus tag: Shewmr4_0928
Name: metY
Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)

Position: -97
Score: 6.3
Sequence: GGGCGTCT-(0)-GGACGTCT
Position: -89
Score: 6.4
Sequence: GGACGTCT-(0)-AGAAGTTT
Locus tag: Shewmr4_3300
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -118
Score: 6.3
Sequence: GGACGTCT-(0)-ATACGTAT
Position: -110
Score: 5.7
Sequence: ATACGTAT-(0)-AAATGTCC
Locus tag: Shewmr4_0838
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -181
Score: 7
Sequence: AGATGTCT-(0)-GGACGTCT
Position: -173
Score: 6
Sequence: GGACGTCT-(0)-AAATGTAC
Position: -134
Score: 5.6
Sequence: AGGCGTTA-(0)-AGACGTTT
Position: -126
Score: 7.3
Sequence: AGACGTTT-(0)-AGACGTCT
Position: -118
Score: 6.1
Sequence: AGACGTCT-(0)-AAACATAA
Locus tag: Shewmr4_3440
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -29
Score: 6.5
Sequence: AGCCATCT-(0)-AGACTTCT
Locus tag: Shewmr4_2030
Name: msrA
Funciton: Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)
msrA
Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)

Position: -152
Score: 7.1
Sequence: AAACATCT-(0)-AGACGTCT
Position: -144
Score: 5.6
Sequence: AGACGTCT-(0)-AGATTGAC
Locus tag: Shewmr4_0919
Name: metT
Funciton: Methionine transporter MetT, NhaC antiporter family
metT
Methionine transporter MetT, NhaC antiporter family

Position: -431
Score: 6.2
Sequence: ATCCGTAT-(0)-AGACGTCT
Locus tag: Shewmr4_3302
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
btuB
TonB-dependent outer membrane transporter for vitamin B12
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