Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Fnr in Shewanella sp MR-4

Properties
Regulator type: Transcription factor
TF locus tag: Shewmr4_2014
Regulator family: CRP
Regulation mode:
Biological process: Anaerobic metabolism
Effector: Oxygen
Regulog: Fnr - Shewanellaceae
Statistics of regulated genes:
- Genes 94
- Operons 33
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 541 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -153
Score: 4.5
Sequence: GTGATGTGAATCAT
Locus tag: Shewmr4_1573
Name: ydhD
Funciton: Glutaredoxin-related protein
ydhD
Glutaredoxin-related protein

Position: -353
Score: 4.2
Sequence: TTTACCTAGATCAA
Locus tag: Shewmr4_2506
Name: mtrD
Funciton: Periplasmic decaheme cytochrome c, MtrD
Locus tag: Shewmr4_2507
Name: mtrE
Funciton: Outer membrane protein, MtrE
Locus tag: Shewmr4_2508
Name: mtrF
Funciton: Decaheme cytochrome c, MtrF
mtrD
Periplasmic decaheme cytochrome c, MtrD
mtrE
Outer membrane protein, MtrE
mtrF
Decaheme cytochrome c, MtrF

Position: -75
Score: 4.9
Sequence: TTGATTTACATCAA
Locus tag: Shewmr4_2225
Name: narK
Funciton: Nitrate/nitrite antiporter
narK
Nitrate/nitrite antiporter

Position: -158
Score: 4.6
Sequence: TTGATCCAGATCAC
Locus tag: Shewmr4_2867
Name: cyaB
Funciton: Adenylate cyclase (EC 4.6.1.1)
cyaB
Adenylate cyclase (EC 4.6.1.1)

Position: -91
Score: 4.2
Sequence: GTGATAAGGATCAA
Locus tag: Shewmr4_0396
Name: hupE
Funciton: Predicted metal transporter
hupE
Predicted metal transporter

Position: -182
Score: 4.3
Sequence: CTGTTCTAGATCAA
Locus tag: Shewmr4_3723
Name: fdhX2
Funciton: Formate dehydrogenase, subunit or accessory protein
Locus tag: Shewmr4_3724
Name: fdhA2
Funciton: Formate dehydrogenase, major subunit (EC 1.2.1.2)
Locus tag: Shewmr4_3725
Name: fdhB2
Funciton: Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
Locus tag: Shewmr4_3726
Name: fdhC2
Funciton: Formate dehydrogenase, gamma subunit (EC 1.2.1.2)
fdhX2
Formate dehydrogenase, subunit or accessory protein
fdhA2
Formate dehydrogenase, major subunit (EC 1.2.1.2)
fdhB2
Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
fdhC2
Formate dehydrogenase, gamma subunit (EC 1.2.1.2)

Position: -104
Score: 5
Sequence: TTGATCTAGCGCAA
Locus tag: Shewmr4_0659
Name: nrfA
Funciton: Nitrite reductase, cytochrome c(552) (EC 1.7.2.2)
nrfA
Nitrite reductase, cytochrome c(552) (EC 1.7.2.2)

Position: -183
Score: 4.8
Sequence: TTGAGGTGGATCAT
Locus tag: Shewmr4_3714
Name: fdhD
Funciton: Formate dehydrogenase chain D (EC 1.2.1.2)
Locus tag: Shewmr4_3713
Name: SO4502
Funciton: Conserved hupothetical protein
fdhD
Formate dehydrogenase chain D (EC 1.2.1.2)
SO4502
Conserved hupothetical protein

Position: -338
Score: 4.9
Sequence: TTGATTTGAATCAA
Locus tag: Shewmr4_1239
Name: cydA
Funciton: Cytochrome d ubiquinol oxidase, subunit I (EC 1.10.3.-)
Locus tag: Shewmr4_1240
Name: cydB
Funciton: Cytochrome d ubiquinol oxidase, subunit II (EC 1.10.3.-)
Locus tag: Shewmr4_1241
Name: ybgT
Funciton: Cyd operon protein YbgT
cydA
Cytochrome d ubiquinol oxidase, subunit I (EC 1.10.3.-)
cydB
Cytochrome d ubiquinol oxidase, subunit II (EC 1.10.3.-)
ybgT
Cyd operon protein YbgT

Position: -164
Score: 5.4
Sequence: ATGATCTGGATCAA
Locus tag: Shewmr4_1840
Name: napE2
Funciton: Periplasmic nitrate reductase component NapE
Locus tag: Shewmr4_1841
Name: napD2
Funciton: Periplasmic nitrate reductase component NapD
Locus tag: Shewmr4_1842
Name: napA2
Funciton: Periplasmic nitrate reductase precursor (EC 1.7.99.4)
Locus tag: Shewmr4_1843
Name: napB2
Funciton: Nitrate reductase cytochrome c550-type subunit
Locus tag: Shewmr4_1844
Name: napC2
Funciton: Cytochrome c-type protein NapC
napE2
Periplasmic nitrate reductase component NapE
napD2
Periplasmic nitrate reductase component NapD
napA2
Periplasmic nitrate reductase precursor (EC 1.7.99.4)
napB2
Nitrate reductase cytochrome c550-type subunit
napC2
Cytochrome c-type protein NapC

Position: -314
Score: 4.9
Sequence: GTGATCTTGATCAA
Locus tag: Shewmr4_3791
Name: coxB
Funciton: Cytochrome c oxidase, polypeptide II (EC 1.9.3.1)
Locus tag: Shewmr4_3792
Name: coxA
Funciton: Cytochrome c oxidase, polypeptide I (EC 1.9.3.1)
Locus tag: Shewmr4_3793
Name: coxZ
Funciton: Cytochrome c oxidase biogenesis protein, predicted copper delivery
Locus tag: Shewmr4_3794
Name: coxC
Funciton: Cytochrome c oxidase, polypeptide III (EC 1.9.3.1)
coxB
Cytochrome c oxidase, polypeptide II (EC 1.9.3.1)
coxA
Cytochrome c oxidase, polypeptide I (EC 1.9.3.1)
coxZ
Cytochrome c oxidase biogenesis protein, predicted copper delivery
coxC
Cytochrome c oxidase, polypeptide III (EC 1.9.3.1)

Position: -122
Score: 4.7
Sequence: GTGATATAGATCAT
Locus tag: Shewmr4_0764
Name: gltP
Funciton: Sodium/glutamate symport protein
gltP
Sodium/glutamate symport protein

Position: -103
Score: 5.2
Sequence: TTGATTTGGATCAA
Locus tag: Shewmr4_2601
Name: ompW
Funciton: Outer membrane protein W precursor
ompW
Outer membrane protein W precursor

Position: -135
Score: 4.9
Sequence: TTGCGCTAGATCAA
Locus tag: Shewmr4_0658
Name: narQ
Funciton: Nitrate/nitrite sensor protein NarQ (EC 2.7.3.-)
Locus tag: Shewmr4_0657
Name: narP
Funciton: Nitrate/nitrite response regulator protein NarP, LuxR family
narQ
Nitrate/nitrite sensor protein NarQ (EC 2.7.3.-)
narP
Nitrate/nitrite response regulator protein NarP, LuxR family

Position: -202
Score: 4.3
Sequence: TTGATCCGCTTCAA
Locus tag: Shewmr4_0272
Name: etfD
Funciton: Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)
etfD
Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)

Position: -341
Score: 5.1
Sequence: TTGATGTAAATCAA
Locus tag: Shewmr4_2224
Name: narX
Funciton: Nitrate/nitrite sensor protein NarX (EC 2.7.3.-)
Locus tag: Shewmr4_2223
Name: narL
Funciton: Nitrate/nitrite response regulator protein NarL, LuxR family
narX
Nitrate/nitrite sensor protein NarX (EC 2.7.3.-)
narL
Nitrate/nitrite response regulator protein NarL, LuxR family

Position: -95
Score: 4.2
Sequence: GTGATCTATGTCAA
Locus tag: Shewmr4_3765
Name: nrfX
Funciton: Nitrite reductase, predicted component
Locus tag: Shewmr4_3764
Name: nrfB
Funciton: Nitrite reductase, subunit B
Locus tag: Shewmr4_3763
Name: nrfC
Funciton: Nitrite reductase, 4Fe-4S ferredoxin subunit
Locus tag: Shewmr4_3762
Name: nrfD
Funciton: Nitrite reductase, cytochrome c subunit
nrfX
Nitrite reductase, predicted component
nrfB
Nitrite reductase, subunit B
nrfC
Nitrite reductase, 4Fe-4S ferredoxin subunit
nrfD
Nitrite reductase, cytochrome c subunit

Position: -42
Score: 5.3
Sequence: TTGATTTAGATCAA
Locus tag: Shewmr4_0944
Name: bfr2
Funciton: Bacterioferritin
Locus tag: Shewmr4_0945
Name: bfr1
Funciton: Bacterioferritin
bfr2
Bacterioferritin
bfr1
Bacterioferritin

Position: -145
Score: 4.5
Sequence: TTGATGTGAATCTA
Locus tag: Shewmr4_0748
Name: nqrA1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit A (EC 1.6.5.-)
Locus tag: Shewmr4_0749
Name: nqrB1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit B (EC 1.6.5.-)
Locus tag: Shewmr4_0750
Name: nqrC1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit C (EC 1.6.5.-)
Locus tag: Shewmr4_0751
Name: nqrD1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit D (EC 1.6.5.-)
Locus tag: Shewmr4_0752
Name: nqrE1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit E (EC 1.6.5.-)
Locus tag: Shewmr4_0753
Name: nqrF1
Funciton: Na(+)-translocating NADH-quinone reductase, subunit F (EC 1.6.5.-)
nqrA1
Na(+)-translocating NADH-quinone reductase, subunit A (EC 1.6.5.-)
nqrB1
Na(+)-translocating NADH-quinone reductase, subunit B (EC 1.6.5.-)
nqrC1
Na(+)-translocating NADH-quinone reductase, subunit C (EC 1.6.5.-)
nqrD1
Na(+)-translocating NADH-quinone reductase, subunit D (EC 1.6.5.-)
nqrE1
Na(+)-translocating NADH-quinone reductase, subunit E (EC 1.6.5.-)
nqrF1
Na(+)-translocating NADH-quinone reductase, subunit F (EC 1.6.5.-)

Position: -145
Score: 4.2
Sequence: TTGATCCCGATCGA
Locus tag: Shewmr4_0705
Name: napD
Funciton: Periplasmic nitrate reductase component NapD
Locus tag: Shewmr4_0704
Name: napA
Funciton: Periplasmic nitrate reductase precursor (EC 1.7.99.4)
Locus tag: Shewmr4_0703
Name: napG
Funciton: Periplasmic nitrate reductase, ferredoxin-type protein NapG
Locus tag: Shewmr4_0702
Name: napH
Funciton: Polyferredoxin NapH (periplasmic nitrate reductase)
Locus tag: Shewmr4_0701
Name: napB
Funciton: Nitrate reductase cytochrome c550-type subunit
napD
Periplasmic nitrate reductase component NapD
napA
Periplasmic nitrate reductase precursor (EC 1.7.99.4)
napG
Periplasmic nitrate reductase, ferredoxin-type protein NapG
napH
Polyferredoxin NapH (periplasmic nitrate reductase)
napB
Nitrate reductase cytochrome c550-type subunit

Position: -72
Score: 4.9
Sequence: TTGATCTAGAACAA
Locus tag: Shewmr4_2015
Name: uspE
Funciton: Universal stress protein E
uspE
Universal stress protein E

Position: -210
Score: 5.6
Sequence: TTGATCTAGATCAA
Position: -167
Score: 4.2
Sequence: TTGACATGGCTCAA
Locus tag: Shewmr4_2006
Name: ccoN
Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoN (EC 1.9.3.1)
Locus tag: Shewmr4_2007
Name: ccoO
Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoO (EC 1.9.3.1)
Locus tag: Shewmr4_2008
Name: ccoQ
Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoQ (EC 1.9.3.1)
Locus tag: Shewmr4_2009
Name: ccoP
Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoP (EC 1.9.3.1)
Locus tag: Shewmr4_2010
Name: ccoH
Funciton: Cytochrome c oxidase, cbb3-type, biogenesis protein CcoH
Locus tag: Shewmr4_2011
Name: ccoI
Funciton: Cytochrome c oxidase, maturation protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4)
Locus tag: Shewmr4_2012
Name: ccoS
Funciton: Cytochrome c oxidase, maturation protein CcoS, involved in heme b insertion
Locus tag: Shewmr4_2013
Name: ccoX
Funciton: Cytochrome c oxidase, cbb3-type, predicted component
Locus tag: Shewmr4_2014
Name: fnr
Funciton: Anaerobic metabolism transcriptional regulator Fnr, Fnr family
ccoN
Cytochrome c oxidase, cbb3-type, subunit CcoN (EC 1.9.3.1)
ccoO
Cytochrome c oxidase, cbb3-type, subunit CcoO (EC 1.9.3.1)
ccoQ
Cytochrome c oxidase, cbb3-type, subunit CcoQ (EC 1.9.3.1)
ccoP
Cytochrome c oxidase, cbb3-type, subunit CcoP (EC 1.9.3.1)
ccoH
Cytochrome c oxidase, cbb3-type, biogenesis protein CcoH
ccoI
Cytochrome c oxidase, maturation protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4)
ccoS
Cytochrome c oxidase, maturation protein CcoS, involved in heme b insertion
ccoX
Cytochrome c oxidase, cbb3-type, predicted component
fnr
Anaerobic metabolism transcriptional regulator Fnr, Fnr family

Position: -177
Score: 5.3
Sequence: ATGATCTAGATCAT
Locus tag: Shewmr4_2734
Name: lldP
Funciton: L-lactate permease
Locus tag: Shewmr4_2735
Name: dld
Funciton: Predicted lactate dehydrogenase, Fe-S protein, FAD/FMN-containing
lldP
L-lactate permease
dld
Predicted lactate dehydrogenase, Fe-S protein, FAD/FMN-containing

Position: -68
Score: 5
Sequence: TTGATCCAAATCAA
Locus tag: Shewmr4_2996
Name: hmp
Funciton: Nitric oxide dioxygenase (EC 1.14.12.17)
hmp
Nitric oxide dioxygenase (EC 1.14.12.17)

Position: -162
Score: 4.3
Sequence: TAGATCTGCATCAT
Position: -102
Score: 4.8
Sequence: TTGATATGCATCAA
Locus tag: Shewmr4_1822
Name: hyaA
Funciton: Ni/Fe-hydrogenase, small chain precursor (EC 1.12.5.1)
Locus tag: Shewmr4_1821
Name: hyaB
Funciton: Ni/Fe-hydrogenase, large chain (EC 1.12.5.1)
Locus tag: Shewmr4_1820
Name: hyaC
Funciton: Ni/Fe hydrogenase, cytochrome b subunit (EC 1.12.5.1)
Locus tag: Shewmr4_1819
Name: hyaD
Funciton: Ni/Fe hydrogenase, maturation protease (EC 1.12.5.1)
Locus tag: Shewmr4_1818
Name: hyaE
Funciton: Ni/Fe hydrogenase, predicted component (EC 1.12.5.1)
Locus tag: Shewmr4_1817
Name: hyaF
Funciton: Ni/Fe hydrogenase, metallocenter assembly protein (EC 1.12.5.1)
hyaA
Ni/Fe-hydrogenase, small chain precursor (EC 1.12.5.1)
hyaB
Ni/Fe-hydrogenase, large chain (EC 1.12.5.1)
hyaC
Ni/Fe hydrogenase, cytochrome b subunit (EC 1.12.5.1)
hyaD
Ni/Fe hydrogenase, maturation protease (EC 1.12.5.1)
hyaE
Ni/Fe hydrogenase, predicted component (EC 1.12.5.1)
hyaF
Ni/Fe hydrogenase, metallocenter assembly protein (EC 1.12.5.1)

Position: -82
Score: 4.3
Sequence: TTGATTTACATCAC
Locus tag: Shewmr4_1948
Name: Sama_2599
Funciton: Predicted lipoprotein
Sama_2599
Predicted lipoprotein

Position: -121
Score: 5.2
Sequence: ATGATCTGGATCAT
Locus tag: Shewmr4_2441
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: Shewmr4_2440
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

Position: -87
Score: 4.3
Sequence: TTGATCTAGGTAAA
Locus tag: Shewmr4_2505
Name: feoA
Funciton: Ferrous iron transport protein A
Locus tag: Shewmr4_2504
Name: feoB
Funciton: Ferrous iron transport protein B
feoA
Ferrous iron transport protein A
feoB
Ferrous iron transport protein B

Position: -154
Score: 4.9
Sequence: TTGATATAAATCAA
Locus tag: Shewmr4_0579
Name: SO0579
Funciton: Predicted serine/threonine protein kinase
SO0579
Predicted serine/threonine protein kinase

Position: -103
Score: 4.3
Sequence: TTGATCTAACTCAG
Locus tag: Shewmr4_0403
Name: frdC1
Funciton: Fumarate reductase, cytochrome b subunit
Locus tag: Shewmr4_0404
Name: frdA
Funciton: Fumarate reductase, flavoprotein subunit
Locus tag: Shewmr4_0405
Name: frdB
Funciton: Fumarate reductase, iron-sulfur protein (EC 1.3.99.1)
frdC1
Fumarate reductase, cytochrome b subunit
frdA
Fumarate reductase, flavoprotein subunit
frdB
Fumarate reductase, iron-sulfur protein (EC 1.3.99.1)

Position: -152
Score: 4.7
Sequence: TTGAAGCGGATCAA
Locus tag: Shewmr4_0273
Name: moaA
Funciton: Molybdenum cofactor biosynthesis protein MoaA
Locus tag: Shewmr4_0274
Name: moaC
Funciton: Molybdenum cofactor biosynthesis protein MoaC
Locus tag: Shewmr4_0275
Name: moaD
Funciton: Molybdenum cofactor biosynthesis protein D
Locus tag: Shewmr4_0276
Name: moaE
Funciton: Molybdenum cofactor biosynthesis protein MoaE
Locus tag: Shewmr4_0277
Name: modA
Funciton: Molybdenum ABC transporter, substrate-binding protein (TC 3.A.1.8.1)
Locus tag: Shewmr4_0278
Name: modB
Funciton: Molybdenum ABC transporter, permease protein (TC 3.A.1.8.1)
Locus tag: Shewmr4_0279
Name: modC
Funciton: Molybdenum ABC transporter, ATP-binding protein (TC 3.A.1.8.1)
moaA
Molybdenum cofactor biosynthesis protein MoaA
moaC
Molybdenum cofactor biosynthesis protein MoaC
moaD
Molybdenum cofactor biosynthesis protein D
moaE
Molybdenum cofactor biosynthesis protein MoaE
modA
Molybdenum ABC transporter, substrate-binding protein (TC 3.A.1.8.1)
modB
Molybdenum ABC transporter, permease protein (TC 3.A.1.8.1)
modC
Molybdenum ABC transporter, ATP-binding protein (TC 3.A.1.8.1)

Position: -80
Score: 4.2
Sequence: GTGAGCTTAATCAA
Locus tag: Shewmr4_1149
Name: aer
Funciton: Aerotaxis sensor receptor protein
aer
Aerotaxis sensor receptor protein

Position: -127
Score: 4.5
Sequence: ATGATCCACCTCAA
Locus tag: Shewmr4_3715
Name: SO4504
Funciton: Conserved hypothetical protein
Locus tag: Shewmr4_3716
Name: SO4505
Funciton: Predicted formate dehydrogenase associated protein
Locus tag: Shewmr4_3717
Name: SO4506
Funciton: Predicted iron-sulfur cluster-binding protein
Locus tag: Shewmr4_3718
Name: SO4507
Funciton: Predicted formate dehydrogenase-specific chaperone
Locus tag: Shewmr4_3719
Name: fdhX
Funciton: Formate dehydrogenase subunit or accessory protein
Locus tag: Shewmr4_3720
Name: fdhA1
Funciton: Formate dehydrogenase, major subunit (EC 1.2.1.2)
Locus tag: Shewmr4_3721
Name: fdhB1
Funciton: Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
Locus tag: Shewmr4_3722
Name: fdhC1
Funciton: Formate dehydrogenase, gamma subunit
SO4504
Conserved hypothetical protein
SO4505
Predicted formate dehydrogenase associated protein
SO4506
Predicted iron-sulfur cluster-binding protein
SO4507
Predicted formate dehydrogenase-specific chaperone
fdhX
Formate dehydrogenase subunit or accessory protein
fdhA1
Formate dehydrogenase, major subunit (EC 1.2.1.2)
fdhB1
Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
fdhC1
Formate dehydrogenase, gamma subunit
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