Regulon of Fnr in Shewanella pealeana ATCC 700345

Properties
Regulator type:	Transcription factor
TF locus tag:	Spea_2222
Regulator family:	CRP
Regulation mode:
Biological process:	Anaerobic metabolism
Effector:	Oxygen
Regulog:	Fnr - Shewanellaceae
Statistics of regulated genes:
- Genes	90
- Operons	34
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 541 sites [see more]

Member of regulog collections

By taxonomy - Shewanellaceae
By TF family - CRP
By effector - Oxygen
By pathway - Anaerobic metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -150 Score: 3.9 Sequence: GTGAAGTGTATCAT Locus tag: Spea_1964 Name: ydhD Funciton: Glutaredoxin-related protein
	Spea_1964	ydhD	Glutaredoxin-related protein
Position: -138 Score: 4.2 Sequence: ATGATCTACAACAT Position: -78 Score: 4.2 Sequence: TTGACTGAGATCAA Locus tag: Spea_0593 Name: Sama_0549 Funciton: Conserved hypothetical protein
	Spea_0593	Sama_0549	Conserved hypothetical protein
Position: -344 Score: 4.2 Sequence: TTTACCTAGATCAA Locus tag: Spea_2692 Name: mtrD Funciton: Periplasmic decaheme cytochrome c, MtrD Locus tag: Spea_2693 Name: mtrE Funciton: Outer membrane protein, MtrE Locus tag: Spea_2694 Name: mtrF Funciton: Decaheme cytochrome c, MtrF
	Spea_2692	mtrD	Periplasmic decaheme cytochrome c, MtrD
	Spea_2693	mtrE	Outer membrane protein, MtrE
	Spea_2694	mtrF	Decaheme cytochrome c, MtrF
Position: -96 Score: 4 Sequence: TTGACTTAGATCAC Locus tag: Spea_1019 Name: cyaB Funciton: Adenylate cyclase (EC 4.6.1.1)
	Spea_1019	cyaB	Adenylate cyclase (EC 4.6.1.1)
Position: -337 Score: 4.9 Sequence: TTGATTTGAATCAA Position: -51 Score: 4.4 Sequence: TTGATGGGGATCTA Locus tag: Spea_1318 Name: cydA Funciton: Cytochrome d ubiquinol oxidase, subunit I (EC 1.10.3.-) Locus tag: Spea_1319 Name: cydB Funciton: Cytochrome d ubiquinol oxidase, subunit II (EC 1.10.3.-) Locus tag: Spea_1320 Name: ybgT Funciton: Cyd operon protein YbgT
	Spea_1318	cydA	Cytochrome d ubiquinol oxidase, subunit I (EC 1.10.3.-)
	Spea_1319	cydB	Cytochrome d ubiquinol oxidase, subunit II (EC 1.10.3.-)
	Spea_1320	ybgT	Cyd operon protein YbgT
Position: -215 Score: 5.6 Sequence: TTGATCTAGATCAA Position: -172 Score: 4.9 Sequence: TTGATATAGCTCAA Locus tag: Spea_2214 Name: ccoN Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoN (EC 1.9.3.1) Locus tag: Spea_2215 Name: ccoO Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoO (EC 1.9.3.1) Locus tag: Spea_2216 Name: ccoQ Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoQ (EC 1.9.3.1) Locus tag: Spea_2217 Name: ccoP Funciton: Cytochrome c oxidase, cbb3-type, subunit CcoP (EC 1.9.3.1) Locus tag: Spea_2218 Name: ccoH Funciton: Cytochrome c oxidase, cbb3-type, biogenesis protein CcoH Locus tag: Spea_2219 Name: ccoI Funciton: Cytochrome c oxidase, maturation protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) Locus tag: Spea_2220 Name: ccoS Funciton: Cytochrome c oxidase, maturation protein CcoS, involved in heme b insertion Locus tag: Spea_2221 Name: ccoX Funciton: Cytochrome c oxidase, cbb3-type, predicted component Locus tag: Spea_2222 Name: fnr Funciton: Anaerobic metabolism transcriptional regulator Fnr, Fnr family
	Spea_2214	ccoN	Cytochrome c oxidase, cbb3-type, subunit CcoN (EC 1.9.3.1)
	Spea_2215	ccoO	Cytochrome c oxidase, cbb3-type, subunit CcoO (EC 1.9.3.1)
	Spea_2216	ccoQ	Cytochrome c oxidase, cbb3-type, subunit CcoQ (EC 1.9.3.1)
	Spea_2217	ccoP	Cytochrome c oxidase, cbb3-type, subunit CcoP (EC 1.9.3.1)
	Spea_2218	ccoH	Cytochrome c oxidase, cbb3-type, biogenesis protein CcoH
	Spea_2219	ccoI	Cytochrome c oxidase, maturation protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4)
	Spea_2220	ccoS	Cytochrome c oxidase, maturation protein CcoS, involved in heme b insertion
	Spea_2221	ccoX	Cytochrome c oxidase, cbb3-type, predicted component
	Spea_2222	fnr	Anaerobic metabolism transcriptional regulator Fnr, Fnr family
Position: -119 Score: 5 Sequence: TTGATCTAGTTCAA Locus tag: Spea_4142 Name: SO4504 Funciton: Conserved hypothetical protein Locus tag: Spea_4141 Name: SO4505 Funciton: Predicted formate dehydrogenase associated protein Locus tag: Spea_4140 Name: SO4506 Funciton: Predicted iron-sulfur cluster-binding protein Locus tag: Spea_4139 Name: SO4507 Funciton: Predicted formate dehydrogenase-specific chaperone Locus tag: Spea_4138 Name: fdhX Funciton: Formate dehydrogenase subunit or accessory protein Locus tag: Spea_4137 Name: fdhA1 Funciton: Formate dehydrogenase, major subunit (EC 1.2.1.2) Locus tag: Spea_4136 Name: fdhB1 Funciton: Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2) Locus tag: Spea_4135 Name: fdhC1 Funciton: Formate dehydrogenase, gamma subunit
	Spea_4142	SO4504	Conserved hypothetical protein
	Spea_4141	SO4505	Predicted formate dehydrogenase associated protein
	Spea_4140	SO4506	Predicted iron-sulfur cluster-binding protein
	Spea_4139	SO4507	Predicted formate dehydrogenase-specific chaperone
	Spea_4138	fdhX	Formate dehydrogenase subunit or accessory protein
	Spea_4137	fdhA1	Formate dehydrogenase, major subunit (EC 1.2.1.2)
	Spea_4136	fdhB1	Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
	Spea_4135	fdhC1	Formate dehydrogenase, gamma subunit
Position: -134 Score: 4.4 Sequence: GTGATCTTGATCTA Locus tag: Spea_0392 Name: frdC2 Funciton: Fumarate reductase, cytochrome b subunit Locus tag: Spea_0393 Name: frdC1 Funciton: Fumarate reductase, cytochrome b subunit Locus tag: Spea_0394 Name: frdA Funciton: Fumarate reductase, flavoprotein subunit Locus tag: Spea_0395 Name: frdB Funciton: Fumarate reductase, iron-sulfur protein (EC 1.3.99.1)
	Spea_0392	frdC2	Fumarate reductase, cytochrome b subunit
	Spea_0393	frdC1	Fumarate reductase, cytochrome b subunit
	Spea_0394	frdA	Fumarate reductase, flavoprotein subunit
	Spea_0395	frdB	Fumarate reductase, iron-sulfur protein (EC 1.3.99.1)
Position: -199 Score: 3.9 Sequence: CGGATTTAGATCAA Locus tag: Spea_4130 Name: fdhX2 Funciton: Formate dehydrogenase, subunit or accessory protein Locus tag: Spea_4129 Name: fdhA2 Funciton: Formate dehydrogenase, major subunit (EC 1.2.1.2) Locus tag: Spea_4128 Name: fdhB2 Funciton: Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2) Locus tag: Spea_4127 Name: fdhC2 Funciton: Formate dehydrogenase, gamma subunit (EC 1.2.1.2)
	Spea_4130	fdhX2	Formate dehydrogenase, subunit or accessory protein
	Spea_4129	fdhA2	Formate dehydrogenase, major subunit (EC 1.2.1.2)
	Spea_4128	fdhB2	Formate dehydrogenase, iron-sulfur subunit (EC 1.2.1.2)
	Spea_4127	fdhC2	Formate dehydrogenase, gamma subunit (EC 1.2.1.2)
Position: -191 Score: 5.4 Sequence: ATGATCTGGATCAA Locus tag: Spea_2429 Name: napE2 Funciton: Periplasmic nitrate reductase component NapE Locus tag: Spea_2428 Name: napD2 Funciton: Periplasmic nitrate reductase component NapD Locus tag: Spea_2427 Name: napA2 Funciton: Periplasmic nitrate reductase precursor (EC 1.7.99.4) Locus tag: Spea_2426 Name: napB2 Funciton: Nitrate reductase cytochrome c550-type subunit Locus tag: Spea_2425 Name: napC2 Funciton: Cytochrome c-type protein NapC
	Spea_2429	napE2	Periplasmic nitrate reductase component NapE
	Spea_2428	napD2	Periplasmic nitrate reductase component NapD
	Spea_2427	napA2	Periplasmic nitrate reductase precursor (EC 1.7.99.4)
	Spea_2426	napB2	Nitrate reductase cytochrome c550-type subunit
	Spea_2425	napC2	Cytochrome c-type protein NapC
Position: -128 Score: 4.6 Sequence: TTGATCTACCGCAA Locus tag: Spea_0831 Name: nrfA Funciton: Nitrite reductase, cytochrome c(552) (EC 1.7.2.2)
	Spea_0831	nrfA	Nitrite reductase, cytochrome c(552) (EC 1.7.2.2)
Position: -128 Score: 4.6 Sequence: TTGCGGTAGATCAA Locus tag: Spea_0830 Name: narQ Funciton: Nitrate/nitrite sensor protein NarQ (EC 2.7.3.-) Locus tag: Spea_0829 Name: narP Funciton: Nitrate/nitrite response regulator protein NarP, LuxR family
	Spea_0830	narQ	Nitrate/nitrite sensor protein NarQ (EC 2.7.3.-)
	Spea_0829	narP	Nitrate/nitrite response regulator protein NarP, LuxR family
Position: -74 Score: 4.6 Sequence: TTGATCTAAAACAA Locus tag: Spea_2223 Name: uspE Funciton: Universal stress protein E
	Spea_2223	uspE	Universal stress protein E
Position: -33 Score: 5.2 Sequence: TTGATATAGATCAA Locus tag: Spea_3095 Name: bfr2 Funciton: Bacterioferritin Locus tag: Spea_3094 Name: bfr1 Funciton: Bacterioferritin
	Spea_3095	bfr2	Bacterioferritin
	Spea_3094	bfr1	Bacterioferritin
Position: -108 Score: 4.9 Sequence: GTGATGTAGATCAT Locus tag: Spea_0775 Name: gltP Funciton: Sodium/glutamate symport protein
	Spea_0775	gltP	Sodium/glutamate symport protein
Position: -155 Score: 4.3 Sequence: GTGATCTAGATCCT Position: -104 Score: 5.3 Sequence: TTGATTTAGATCAA Locus tag: Spea_2787 Name: ompW Funciton: Outer membrane protein W precursor
	Spea_2787	ompW	Outer membrane protein W precursor
Position: -181 Score: 5.3 Sequence: TTGATCTAGCTCAA Locus tag: Spea_3494 Name: cydD Funciton: Transport ATP-binding protein CydD Locus tag: Spea_3493 Name: cydC Funciton: Transport ATP-binding protein CydC
	Spea_3494	cydD	Transport ATP-binding protein CydD
	Spea_3493	cydC	Transport ATP-binding protein CydC
Position: -95 Score: 4.7 Sequence: TTGAGTTAGATCAT Locus tag: Spea_2337 Name: pykA Funciton: Pyruvate kinase (EC 2.7.1.40)
	Spea_2337	pykA	Pyruvate kinase (EC 2.7.1.40)
Position: -93 Score: 4.7 Sequence: TTGATTTATATCAA Locus tag: Spea_3968 Name: nrfX Funciton: Nitrite reductase, predicted component Locus tag: Spea_3967 Name: nrfB Funciton: Nitrite reductase, subunit B Locus tag: Spea_3966 Name: nrfC Funciton: Nitrite reductase, 4Fe-4S ferredoxin subunit Locus tag: Spea_3965 Name: nrfD Funciton: Nitrite reductase, cytochrome c subunit
	Spea_3968	nrfX	Nitrite reductase, predicted component
	Spea_3967	nrfB	Nitrite reductase, subunit B
	Spea_3966	nrfC	Nitrite reductase, 4Fe-4S ferredoxin subunit
	Spea_3965	nrfD	Nitrite reductase, cytochrome c subunit
Position: -190 Score: 4.9 Sequence: ATGATCCAGATCAT Locus tag: Spea_2994 Name: lldP Funciton: L-lactate permease Locus tag: Spea_2995 Name: dld Funciton: Predicted lactate dehydrogenase, Fe-S protein, FAD/FMN-containing
	Spea_2994	lldP	L-lactate permease
	Spea_2995	dld	Predicted lactate dehydrogenase, Fe-S protein, FAD/FMN-containing
Position: -349 Score: 4.9 Sequence: GTGATCTTGATCAA Position: -246 Score: 4.2 Sequence: TAGATCCTGATCAA Locus tag: Spea_3999 Name: coxB Funciton: Cytochrome c oxidase, polypeptide II (EC 1.9.3.1) Locus tag: Spea_4000 Name: coxA Funciton: Cytochrome c oxidase, polypeptide I (EC 1.9.3.1) Locus tag: Spea_4001 Name: coxZ Funciton: Cytochrome c oxidase biogenesis protein, predicted copper delivery Locus tag: Spea_4002 Name: coxC Funciton: Cytochrome c oxidase, polypeptide III (EC 1.9.3.1)
	Spea_3999	coxB	Cytochrome c oxidase, polypeptide II (EC 1.9.3.1)
	Spea_4000	coxA	Cytochrome c oxidase, polypeptide I (EC 1.9.3.1)
	Spea_4001	coxZ	Cytochrome c oxidase biogenesis protein, predicted copper delivery
	Spea_4002	coxC	Cytochrome c oxidase, polypeptide III (EC 1.9.3.1)
Position: -240 Score: 3.8 Sequence: TTAATATAGCGCAA Position: -169 Score: 4.9 Sequence: GTGAACTAGATCAA Position: -145 Score: 4.1 Sequence: TTGATCTCGGTCTA Locus tag: Spea_0624 Name: napD Funciton: Periplasmic nitrate reductase component NapD Locus tag: Spea_0623 Name: napA Funciton: Periplasmic nitrate reductase precursor (EC 1.7.99.4) Locus tag: Spea_0622 Name: napG Funciton: Periplasmic nitrate reductase, ferredoxin-type protein NapG Locus tag: Spea_0621 Name: napH Funciton: Polyferredoxin NapH (periplasmic nitrate reductase) Locus tag: Spea_0620 Name: napB Funciton: Nitrate reductase cytochrome c550-type subunit
	Spea_0624	napD	Periplasmic nitrate reductase component NapD
	Spea_0623	napA	Periplasmic nitrate reductase precursor (EC 1.7.99.4)
	Spea_0622	napG	Periplasmic nitrate reductase, ferredoxin-type protein NapG
	Spea_0621	napH	Polyferredoxin NapH (periplasmic nitrate reductase)
	Spea_0620	napB	Nitrate reductase cytochrome c550-type subunit
Position: -179 Score: 5.2 Sequence: TTGAACTAGATCAA Locus tag: Spea_4143 Name: fdhD Funciton: Formate dehydrogenase chain D (EC 1.2.1.2) Locus tag: Spea_4144 Name: SO4502 Funciton: Conserved hupothetical protein
	Spea_4143	fdhD	Formate dehydrogenase chain D (EC 1.2.1.2)
	Spea_4144	SO4502	Conserved hupothetical protein
Position: -113 Score: 4.7 Sequence: GTGATCTTGATCAT Locus tag: Spea_0544 Name: nifS Funciton: Cysteine desulfurase (EC 2.8.1.7)
	Spea_0544	nifS	Cysteine desulfurase (EC 2.8.1.7)
Position: -264 Score: 4.3 Sequence: ATAATTTAGATCAA Locus tag: Spea_0425 Name: acnB Funciton: Aconitate hydratase 2 (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
	Spea_0425	acnB	Aconitate hydratase 2 (EC 4.2.1.3) / 2-methylisocitrate dehydratase (EC 4.2.1.99)
Position: -147 Score: 5.2 Sequence: ATGATCTAGCTCAA Position: -86 Score: 3.8 Sequence: TTGACTCATATCAA Locus tag: Spea_2033 Name: hyaA Funciton: Ni/Fe-hydrogenase, small chain precursor (EC 1.12.5.1) Locus tag: Spea_2032 Name: hyaB Funciton: Ni/Fe-hydrogenase, large chain (EC 1.12.5.1) Locus tag: Spea_2031 Name: hyaC Funciton: Ni/Fe hydrogenase, cytochrome b subunit (EC 1.12.5.1) Locus tag: Spea_2030 Name: hyaD Funciton: Ni/Fe hydrogenase, maturation protease (EC 1.12.5.1) Locus tag: Spea_2029 Name: hyaE Funciton: Ni/Fe hydrogenase, predicted component (EC 1.12.5.1) Locus tag: Spea_2028 Name: hyaF Funciton: Ni/Fe hydrogenase, metallocenter assembly protein (EC 1.12.5.1)
	Spea_2033	hyaA	Ni/Fe-hydrogenase, small chain precursor (EC 1.12.5.1)
	Spea_2032	hyaB	Ni/Fe-hydrogenase, large chain (EC 1.12.5.1)
	Spea_2031	hyaC	Ni/Fe hydrogenase, cytochrome b subunit (EC 1.12.5.1)
	Spea_2030	hyaD	Ni/Fe hydrogenase, maturation protease (EC 1.12.5.1)
	Spea_2029	hyaE	Ni/Fe hydrogenase, predicted component (EC 1.12.5.1)
	Spea_2028	hyaF	Ni/Fe hydrogenase, metallocenter assembly protein (EC 1.12.5.1)
Position: -80 Score: 4.4 Sequence: ATGAACTAGCGCAA Locus tag: Spea_3602 Name: Spea_3602 Funciton: Predicted sensor histidine kinase, two-component system Locus tag: Spea_3601 Name: Spea_3601 Funciton: Predicted response regulator, two-component system Locus tag: Spea_3600 Name: Shal_3689 Funciton: Doubled CXXCH motif protein
	Spea_3602	Spea_3602	Predicted sensor histidine kinase, two-component system
	Spea_3601	Spea_3601	Predicted response regulator, two-component system
	Spea_3600	Shal_3689	Doubled CXXCH motif protein
Position: -157 Score: 4.7 Sequence: TTGATGTTAATCAA Locus tag: Spea_2437 Name: Sama_1615 Funciton: Predicted exported protein
	Spea_2437	Sama_1615	Predicted exported protein
Position: -161 Score: 4.3 Sequence: TTGTTGTAAATCAA Locus tag: Spea_1290 Name: aceB Funciton: Malate synthase (EC 2.3.3.9)
	Spea_1290	aceB	Malate synthase (EC 2.3.3.9)
Position: -186 Score: 4.4 Sequence: TTGATATAGCTCTA Locus tag: Spea_1788 Name: sucA Funciton: 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) Locus tag: Spea_1789 Name: sucB Funciton: 2-oxoglutarate dehydrogenase, E2 component (EC 1.2.4.2) Locus tag: Spea_1790 Name: sucC Funciton: Succinyl-CoA ligase, ADP-forming, beta chain (EC 6.2.1.5) Locus tag: Spea_1791 Name: sucD Funciton: Succinyl-CoA ligase, alpha chain (EC 6.2.1.5)
	Spea_1788	sucA	2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)
	Spea_1789	sucB	2-oxoglutarate dehydrogenase, E2 component (EC 1.2.4.2)
	Spea_1790	sucC	Succinyl-CoA ligase, ADP-forming, beta chain (EC 6.2.1.5)
	Spea_1791	sucD	Succinyl-CoA ligase, alpha chain (EC 6.2.1.5)
Position: -123 Score: 5.4 Sequence: ATGATCTGGATCAA Locus tag: Spea_2619 Name: nrdD Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) Locus tag: Spea_2618 Name: nrdG Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
	Spea_2619	nrdD	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
	Spea_2618	nrdG	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
Position: -92 Score: 4.3 Sequence: TTGATCTAGGTAAA Locus tag: Spea_2691 Name: feoA Funciton: Ferrous iron transport protein A Locus tag: Spea_2690 Name: feoB Funciton: Ferrous iron transport protein B
	Spea_2691	feoA	Ferrous iron transport protein A
	Spea_2690	feoB	Ferrous iron transport protein B
Position: -123 Score: 4.8 Sequence: TTGATATGCATCAA Locus tag: Spea_0586 Name: SO0579 Funciton: Predicted serine/threonine protein kinase
	Spea_0586	SO0579	Predicted serine/threonine protein kinase
Position: -79 Score: 4.5 Sequence: TTGTTTTAGATCAA Locus tag: Spea_3233 Name: Shew_2655 Funciton: Conserved hypothetical protein
	Spea_3233	Shew_2655	Conserved hypothetical protein

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Fnr in Shewanella pealeana ATCC 700345

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --