Regulon of PurR in Streptococcus uberis 0140J

Properties
Regulator type:	Transcription factor
TF locus tag:	SUB1636
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Regulog:	PurR - Streptococcaceae
Statistics of regulated genes:
- Genes	12
- Operons	5
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 100 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - PurR
By effector - 5-phosphoribosyl 1-pyrophosphate
By pathway - Purine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -57 Score: 4 Sequence: ATTCACGAACAAA Locus tag: SUB0053 Name: purD Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) Locus tag: SUB0054 Name: purE Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) Locus tag: SUB0055 Name: purK Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
	SUB0053	purD	Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
	SUB0054	purE	Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
	SUB0055	purK	Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
Position: -187 Score: 4.6 Sequence: AAATCCGAACAAA Locus tag: SUB0865 Name: guaC Funciton: GMP reductase (EC 1.7.1.7)
	SUB0865	guaC	GMP reductase (EC 1.7.1.7)
Position: -108 Score: 5.2 Sequence: AAAAACGAACATT Position: -15 Score: 4.7 Sequence: AAAGGCGAACAAT Locus tag: SUB0025 Name: purC Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) Locus tag: SUB0026 Name: purL Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) Locus tag: SUB0027 Name: purF Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14) Locus tag: SUB0028 Name: purM Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) Locus tag: SUB0029 Name: purN Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Locus tag: SUB0030 Name: purH Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
	SUB0025	purC	Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
	SUB0026	purL	Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
	SUB0027	purF	Amidophosphoribosyltransferase (EC 2.4.2.14)
	SUB0028	purM	Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
	SUB0029	purN	Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
	SUB0030	purH	IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Position: -166 Score: 4.9 Sequence: AAAAGCGAACGTT Locus tag: SUB1480 Name: pbuO Funciton: Guanine/hypoxanthine permease
	SUB1480	pbuO	Guanine/hypoxanthine permease
Position: -88 Score: 4.2 Sequence: AAAGATGAACAAT Locus tag: SUB1636 Name: purR Funciton: Purine metabolism transcriptional regulator PurR, PurR family
	SUB1636	purR	Purine metabolism transcriptional regulator PurR, PurR family

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