Regulon of PurR in Streptococcus pyogenes M1 GAS
Regulator type: | Transcription factor |
TF locus tag: | SPy0268 |
Regulator family: | PurR |
Regulation mode: | repressor |
Biological process: | Purine metabolism |
Effector: | 5-phosphoribosyl 1-pyrophosphate |
Regulog: | PurR - Streptococcaceae |
Statistics of regulated genes: | |
- Genes | 11 |
- Operons | 5 |
Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |

Member of regulog collections
- By taxonomy - Streptococcaceae
- By TF family - PurR
- By effector - 5-phosphoribosyl 1-pyrophosphate
- By pathway - Purine metabolism
Locus Tag | Name | Function | |
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Position: -78
Score: 4.7 Sequence: AAAAACGAACCTT
Locus tag: SPy0024
Name: purC Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: SPy0025
Name: purL Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: SPy0026
Name: purF Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: SPy0027
Name: purM Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: SPy0028
Name: purN Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) |
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purC
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Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
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purL
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Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
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purF
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Amidophosphoribosyltransferase (EC 2.4.2.14)
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purM
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Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
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purN
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Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
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Position: -205
Score: 4.7 Sequence: AAAACCGAACTTT
Locus tag: SPy1135
Name: guaC Funciton: GMP reductase (EC 1.7.1.7) |
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guaC
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GMP reductase (EC 1.7.1.7)
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Position: -55
Score: 4.9 Sequence: AAAAGCGAACGTT
Locus tag: SPy0032
Name: purD Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: SPy0033
Name: purE Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: SPy0034
Name: purK Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) |
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purD
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Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
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purE
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Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
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purK
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Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
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Position: -93
Score: 5.1 Sequence: AAAAACGAACAAT
Locus tag: SPy1213
Name: fhs Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3) |
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fhs
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Formate--tetrahydrofolate ligase (EC 6.3.4.3)
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Position: -102
Score: 5 Sequence: AATACCGAACAAT
Locus tag: SPy1736
Name: pbuO Funciton: Guanine/hypoxanthine permease |
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pbuO
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Guanine/hypoxanthine permease
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |