Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Streptococcus pneumoniae TIGR4

Properties
Regulator type: Transcription factor
TF locus tag: SP_1979
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Streptococcaceae
Statistics of regulated genes:
- Genes 13
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 100 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -56
Score: 4.2
Sequence: TAAAACGAACTTT
Locus tag: SP_0051
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: SP_0052
Name: SP_0052
Funciton: Hypothetical protein
Locus tag: SP_0053
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: SP_0054
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
SP_0052
Hypothetical protein
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -16
Score: 4.3
Sequence: AAAGGCGAACTTT
Locus tag: SP_0044
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: SP_0045
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: SP_0046
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: SP_0047
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: SP_0048
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: SP_0049
Name: ykjJ
Funciton: Teicoplanin resistance protein, predicted
Locus tag: SP_0050
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
ykjJ
Teicoplanin resistance protein, predicted
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

Position: -141
Score: 4.6
Sequence: AAACCCGAACGAT
Locus tag: SP_1249
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -172
Score: 4.6
Sequence: AAAAACGAAGATT
Position: -89
Score: 4.7
Sequence: ATTTACGAACGTT
Locus tag: SP_1229
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD