Regulon of PurR in Streptococcus mutans UA159

Properties
Regulator type:	Transcription factor
TF locus tag:	SMU.356
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Regulog:	PurR - Streptococcaceae
Statistics of regulated genes:
- Genes	14
- Operons	3
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 100 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - PurR
By effector - 5-phosphoribosyl 1-pyrophosphate
By pathway - Purine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -109 Score: 4.8 Sequence: AAATGCGAACGAT Position: -16 Score: 4.7 Sequence: AAAGGCGAACAAT Locus tag: SMU.29 Name: purC Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) Locus tag: SMU.30 Name: purL Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3) Locus tag: SMU.31 Name: null Funciton: DNA alkylation repair enzyme Locus tag: SMU.32 Name: purF Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14) Locus tag: SMU.33 Name: SMU.33 Funciton: Hypothetical protein Locus tag: SMU.34 Name: purM Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) Locus tag: SMU.35 Name: purN Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) Locus tag: SMU.36 Name: SMU.36 Funciton: Hypothetical protein Locus tag: SMU.37 Name: purH Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
	SMU.29	purC	Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
	SMU.30	purL	Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
	SMU.31		DNA alkylation repair enzyme
	SMU.32	purF	Amidophosphoribosyltransferase (EC 2.4.2.14)
	SMU.33	SMU.33	Hypothetical protein
	SMU.34	purM	Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
	SMU.35	purN	Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
	SMU.36	SMU.36	Hypothetical protein
	SMU.37	purH	IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Position: -90 Score: 5.1 Sequence: AAATCCGAACATT Locus tag: SMU.1073 Name: fhs Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
	SMU.1073	fhs	Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Position: -122 Score: 3.5 Sequence: ACTCCCGAACAAA Locus tag: SMU.48 Name: purD Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) Locus tag: SMU.49 Name: carB2 Funciton: Carbamoyl-phosphate synthase large subunit (EC 6.3.5.5) paralog Locus tag: SMU.50 Name: purE Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) Locus tag: SMU.51 Name: purK Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
	SMU.48	purD	Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
	SMU.49	carB2	Carbamoyl-phosphate synthase large subunit (EC 6.3.5.5) paralog
	SMU.50	purE	Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
	SMU.51	purK	Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD