Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Mesorhizobium loti MAFF303099

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Rhizobiales
Under regulation:
- Genes 19
- Operons 6
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -414
Score: 122.4
Sequence: CTAAATCCGCTCCAG...
Locus tag: mlr1374
Name: cfrX
Funciton: Predicted metal-binding protein
Locus tag: mlr1375
Name: cobW
Funciton: CobW GTPase involved in cobalt insertion for B12 biosynthesis
Locus tag: mlr1377
Name: cobN
Funciton: CobN component of cobalt chelatase involved in B12 biosynthesis
Locus tag: mlr1378
Name: cobG
Funciton: Cobalamin biosynthesis protein CobG
Locus tag: mlr1379
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: mlr1380
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: mlr1381
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
cfrX
Predicted metal-binding protein
cobW
CobW GTPase involved in cobalt insertion for B12 biosynthesis
cobN
CobN component of cobalt chelatase involved in B12 biosynthesis
cobG
Cobalamin biosynthesis protein CobG
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiH
Cobalt-precorrin-3b C17-methyltransferase

Position: -212
Score: 131.3
Sequence: TACGGTGGGTGCGTG...
Locus tag: mlr8225
Name: cfrX
Funciton: unknown protein
Locus tag: mlr8227
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: mlr8228
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: mlr8229
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
cfrX
unknown protein
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC

Position: -241
Score: 92.1
Sequence: AAGGTCGCCGCCACT...
Locus tag: mll7468
Name: bluB
Funciton: Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family
bluB
Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family

Position: -317
Score: 130.9
Sequence: GTGATTGTGCGCATG...
Locus tag: mll6123
Name: null
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -217
Score: 120.7
Sequence: CTATAGTCATGCAGT...
Locus tag: msl1310
Name: cbtB
Funciton: Putative cobalt transporter, subunit CbtB
Locus tag: mll1309
Name: cbtA
Funciton: Predicted cobalt transporter CbtA
Locus tag: mll1308
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: mll1306
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbtB
Putative cobalt transporter, subunit CbtB
cbtA
Predicted cobalt transporter CbtA
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

Position: -316
Score: 105.8
Sequence: ATTAGATCATGTCAT...
Locus tag: mll5101
Name: ardX
Funciton: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
Locus tag: mll5100
Name: frdX
Funciton: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
ardX
Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit
frdX
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1
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